Bus Milwaukee to San Diego - Compare all Companies

Compare all timetables for the bus from Milwaukee to San Diego

Here is a selection of the cheapest bus trips from the schedule from Milwaukee to San Diego from various bus operators like FlixBus or Greyhound US for the next days.

today

$163

tomorrow

$145

Saturday

$156

Sunday

$140

Monday

$133

Tuesday

$161

Wednesday

$113

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	65h 10m	8:35 PM	Milwaukee	Central Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$163	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/3/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/6/2026 11:45:00 AM. 50 Economy ticket for $163 per person are available. Travel duration is 65h 10m
Greyhound US	63h 50m	8:35 PM	Milwaukee	Central Bus Station	10:25 AM	San Diego	Seaport Village	Economy	$166	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/3/2026 8:35:00 PM to Seaport Village, San Diego (USA) arriving at 9/6/2026 10:25:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 63h 50m
Greyhound US	63h 30m	8:35 PM	Milwaukee	Central Bus Station	10:05 AM	San Diego	Old Town Transit Center	Economy	$166	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/3/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/6/2026 10:05:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 63h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	57h 25m	9:00 AM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$145	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/4/2026 9:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/6/2026 4:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 57h 25m
Greyhound US	65h 10m	8:35 PM	Milwaukee	Central Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$163	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/4/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 11:45:00 AM. 50 Economy ticket for $163 per person are available. Travel duration is 65h 10m
FlixBus	60h 25m	11:50 AM	Milwaukee	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$164	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/4/2026 11:50:00 AM to Seaport Village, San Diego (USA) arriving at 9/6/2026 10:15:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 60h 25m
Greyhound US	69h 50m	8:35 PM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$165	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/4/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 4:25:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 69h 50m
FlixBus	55h 55m	11:50 AM	Milwaukee	Central Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$166	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/4/2026 11:50:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/6/2026 5:45:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 55h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	57h 25m	9:00 AM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$156	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/5/2026 9:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 4:25:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 57h 25m
FlixBus	56h 55m	9:00 AM	Milwaukee	Central Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$160	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/5/2026 9:00:00 AM to La Jolla Village, San Diego (USA) arriving at 9/7/2026 3:55:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 56h 55m
FlixBus	55h 55m	11:50 AM	Milwaukee	Central Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$172	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/5/2026 11:50:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 5:45:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 55h 55m
Greyhound US	65h 10m	8:35 PM	Milwaukee	Central Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$181	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/5/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/8/2026 11:45:00 AM. 50 Economy ticket for $181 per person are available. Travel duration is 65h 10m
Greyhound US	69h 50m	8:35 PM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$183	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/5/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/8/2026 4:25:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 69h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	57h 25m	9:00 AM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$140	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/6/2026 9:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/8/2026 4:25:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 57h 25m
FlixBus	56h 55m	9:00 AM	Milwaukee	Central Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$144	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/6/2026 9:00:00 AM to La Jolla Village, San Diego (USA) arriving at 9/8/2026 3:55:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 56h 55m
Greyhound US	69h 20m	8:35 PM	Milwaukee	Central Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$162	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/6/2026 8:35:00 PM to La Jolla Village, San Diego (USA) arriving at 9/9/2026 3:55:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 69h 20m
Greyhound US	65h 10m	8:35 PM	Milwaukee	Central Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$166	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/6/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/9/2026 11:45:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 65h 10m
Greyhound US	75h 40m	8:35 PM	Milwaukee	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$166	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/6/2026 8:35:00 PM to Seaport Village, San Diego (USA) arriving at 9/9/2026 10:15:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 75h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	57h 25m	9:00 AM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$133	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/7/2026 9:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/9/2026 4:25:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 57h 25m
FlixBus	56h 55m	9:00 AM	Milwaukee	Central Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$139	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/7/2026 9:00:00 AM to La Jolla Village, San Diego (USA) arriving at 9/9/2026 3:55:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 56h 55m
FlixBus	60h 25m	11:50 AM	Milwaukee	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$144	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/7/2026 11:50:00 AM to Seaport Village, San Diego (USA) arriving at 9/9/2026 10:15:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 60h 25m
Greyhound US	69h 20m	8:35 PM	Milwaukee	Central Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$149	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/7/2026 8:35:00 PM to La Jolla Village, San Diego (USA) arriving at 9/10/2026 3:55:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 69h 20m
Greyhound US	75h 40m	8:35 PM	Milwaukee	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$168	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/7/2026 8:35:00 PM to Seaport Village, San Diego (USA) arriving at 9/10/2026 10:15:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 75h 40m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	67h 20m	6:30 AM	Milwaukee	Central Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$161	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/8/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/10/2026 11:50:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 67h 20m
Greyhound US	65h 10m	8:35 PM	Milwaukee	Central Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$161	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/8/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/11/2026 11:45:00 AM. 50 Economy ticket for $161 per person are available. Travel duration is 65h 10m
FlixBus	57h 25m	9:00 AM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$161	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/8/2026 9:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/10/2026 4:25:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 57h 25m
Greyhound US	69h 50m	8:35 PM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$162	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/8/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/11/2026 4:25:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 69h 50m
FlixBus	60h 20m	11:55 AM	Milwaukee	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$162	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/8/2026 11:55:00 AM to Seaport Village, San Diego (USA) arriving at 9/10/2026 10:15:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 60h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	57h 25m	9:00 AM	Milwaukee	Central Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$113	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/9/2026 9:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/11/2026 4:25:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 57h 25m
Greyhound US	67h 20m	6:30 AM	Milwaukee	Central Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$119	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/9/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/11/2026 11:50:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 67h 20m
Greyhound US	63h 30m	8:35 PM	Milwaukee	Central Bus Station	10:05 AM	San Diego	Old Town Transit Center	Economy	$128	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/9/2026 8:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/12/2026 10:05:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 63h 30m
Greyhound US	63h 50m	8:35 PM	Milwaukee	Central Bus Station	10:25 AM	San Diego	Seaport Village	Economy	$128	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/9/2026 8:35:00 PM to Seaport Village, San Diego (USA) arriving at 9/12/2026 10:25:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 63h 50m
FlixBus	63h 15m	9:00 AM	Milwaukee	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$129	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/9/2026 9:00:00 AM to Seaport Village, San Diego (USA) arriving at 9/11/2026 10:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 63h 15m

Best Price Offer: The price for the cheapest bus from Milwaukee to San Diego is $104 on 9/15/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milwaukee and San Diego

See here how frequent the connections between Milwaukee and San Diego are, during different times and days of the week.

Saturday is the busiest day, with more than 17 daily buses from Milwaukee to San Diego. Thursday has instead the fewest connections, with only 3 daily coaches between Milwaukee and San Diego.

The busiest time of the day is the Morning, with 48 buses from Milwaukee to San Diego, while Evening sees the fewest connections between Milwaukee and San Diego, with 33 offers.

Facts about the bus from Milwaukee to San Diego

Compare all providers like FlixBus and Greyhound US that travel 11 times every day by bus from Milwaukee to San Diego in one click! Book your bus ticket from Milwaukee to San Diego starting from $104!

Cheapest Bus	$104
Fastest Bus	53h 55m
Earliest Bus	8:35 PM
Latest Bus	8:35 PM
Daily Bus Routes	11 Ø
Distance	1,735.2 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Milwaukee to San Diego

Every day, 11 buses from 2 bus companies leave Milwaukee for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/30

Monday 08/31

Tuesday 09/01

Wednesday 09/02

Thursday 09/03

$143

Friday 09/04

$145

Saturday 09/05

$227

Sunday 09/06

$140

Monday 09/07

$133

Tuesday 09/08

$161

Wednesday 09/09

$113

Thursday 09/10

$124

Friday 09/11

$123

Saturday 09/12

$220

Sunday 09/13

$114

Monday 09/14

$115

Tuesday 09/15

$104

Wednesday 09/16

$220

Thursday 09/17

$115

Friday 09/18

$223

Saturday 09/19

$120

Sunday 09/20

$150

Monday 09/21

$125

Tuesday 09/22

$224

Wednesday 09/23

$145

Thursday 09/24

$157

Friday 09/25

$140

Saturday 09/26

The cheapest time to travel from Milwaukee to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Milwaukee to San Diego, for the next 30 days.

With a price starting from $104, Tuesday is the cheapest day for a bus from Milwaukee to San Diego. Friday instead is the most expensive day with prices starting from $123.

Morning is the cheapest day time for bus tickets from Milwaukee to San Diego, with $113. Evening is the most expensive time of the day with prices starting from $128.

How to save money travelling from Milwaukee to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milwaukee to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milwaukee to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milwaukee to San Diego are also emptier.

All bus stations and stops in Milwaukee and San Diego

In the map below, you can see where to find all bus stations in Milwaukee and San Diego.

Intermodal Station

W. St Paul's Ave 433

4960 S. 13th St. Park

Badger

N James Lovell St 635

S84 & Adler

S84 & Oconnor #6533

University

N Maryland Ave 3346

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

Downtown

Service and Comfort on the bus from Milwaukee to San Diego

Want to know which seat classes are available on the buses from Milwaukee to San Diego? Or which bus companies serve the route Milwaukee to San Diego? Below you will find answers to your questions.

FAQs about the Milwaukee to San Diego bus

How much does a Milwaukee San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $104 and takes 55h 25m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Milwaukee to San Diego?

This route is offered by 2 companies with a range of ticket prices between $104 and $252. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Milwaukee to San Diego each day?

Every day, the Milwaukee to San Diego bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milwaukee to San Diego take?

The fastest bus from Milwaukee to San Diego is offered by FlixBus and takes 53h 55m. Bus tickets for this connection cost $166. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milwaukee to San Diego?

The earliest bus arriving in San Diego from Milwaukee starts at 8:35 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milwaukee to San Diego?

The latest bus trip departing from Milwaukee for San Diego starts at 8:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milwaukee San Diego route?

When traveling by bus from Milwaukee to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milwaukee and San Diego?

You can check all the direct connections between Milwaukee and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Milwaukee to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milwaukee San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milwaukee San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milwaukee to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Milwaukee to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 11 daily trips between Milwaukee and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milwaukee to San Diego?

Prices and availability for 11 trips between Milwaukee and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milwaukee to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milwaukee and to San Diego

Here’s an overview of the most popular bus routes to Milwaukee and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!