Bus Pisa to Milan: Compare prices and save money

Compare all timetables for the bus from Pisa to Milan

Here is a selection of the cheapest bus trips from the schedule from Pisa to Milan from various bus operators like FlixBus for the next days.

today

$27

tomorrow

$30

Sunday

$33

Monday

$36

Tuesday

Wednesday

$31

Thursday

$23

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 0m	4:45 PM	Pisa	Pietrasantina Bus Station	9:45 PM	Milan	Lampugnano Bus Station	Economy	$27	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/5/2025 4:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/5/2025 9:45:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
FlixBus	5h 35m	4:50 AM	Pisa	Pietrasantina Bus Station	10:25 AM	Milan	San Donato Bus Station	Economy	$33	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/5/2025 4:50:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/5/2025 10:25:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 5h 35m
FlixBus	6h 20m	4:50 AM	Pisa	Pietrasantina Bus Station	11:10 AM	Milan	Lampugnano Bus Station	Economy	$33	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/5/2025 4:50:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/5/2025 11:10:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 6h 20m
FlixBus	5h 15m	6:25 AM	Pisa	Pietrasantina Bus Station	11:40 AM	Milan	San Donato Bus Station	Economy	$34	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/5/2025 6:25:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/5/2025 11:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 15m
FlixBus	6h 50m	6:15 PM	Pisa	Pietrasantina Bus Station	1:05 AM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/5/2025 6:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/6/2025 1:05:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 6h 50m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 50m	6:15 PM	Pisa	Pietrasantina Bus Station	1:05 AM	Milan	Lampugnano Bus Station	Economy	$30	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/6/2025 6:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 1:05:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 50m
FlixBus	6h 15m	4:45 PM	Pisa	Pietrasantina Bus Station	11:00 PM	Milan	San Donato Bus Station	Economy	$31	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/6/2025 4:45:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/6/2025 11:00:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 6h 15m
FlixBus	5h 15m	1:40 PM	Pisa	Pietrasantina Bus Station	6:55 PM	Milan	Lampugnano Bus Station	Economy	$31	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/6/2025 1:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/6/2025 6:55:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 15m
FlixBus	5h 0m	4:45 PM	Pisa	Pietrasantina Bus Station	9:45 PM	Milan	Lampugnano Bus Station	Economy	$31	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/6/2025 4:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/6/2025 9:45:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 0m
FlixBus	6h 0m	10:00 PM	Pisa	Pietrasantina Bus Station	4:00 AM	Milan	Lampugnano Bus Station	Economy	$32	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/6/2025 10:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 4:00:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 15m	1:40 PM	Pisa	Pietrasantina Bus Station	6:55 PM	Milan	Lampugnano Bus Station	Economy	$33	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/7/2025 1:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 6:55:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 5h 15m
FlixBus	5h 0m	4:45 PM	Pisa	Pietrasantina Bus Station	9:45 PM	Milan	Lampugnano Bus Station	Economy	$33	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/7/2025 4:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 9:45:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 5h 0m
FlixBus	5h 15m	6:25 AM	Pisa	Pietrasantina Bus Station	11:40 AM	Milan	San Donato Bus Station	Economy	$36	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/7/2025 6:25:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/7/2025 11:40:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 5h 15m
FlixBus	6h 50m	6:15 PM	Pisa	Pietrasantina Bus Station	1:05 AM	Milan	Lampugnano Bus Station	Economy	$36	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/7/2025 6:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 1:05:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 6h 50m
FlixBus	6h 0m	10:00 PM	Pisa	Pietrasantina Bus Station	4:00 AM	Milan	Lampugnano Bus Station	Economy	$36	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/7/2025 10:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 4:00:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 6h 0m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 15m	1:40 PM	Pisa	Pietrasantina Bus Station	6:55 PM	Milan	Lampugnano Bus Station	Economy	$36	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/8/2025 1:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 6:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 5h 15m
FlixBus	5h 35m	4:50 AM	Pisa	Pietrasantina Bus Station	10:25 AM	Milan	San Donato Bus Station	Economy	$37	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/8/2025 4:50:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/8/2025 10:25:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 5h 35m
FlixBus	6h 20m	4:50 AM	Pisa	Pietrasantina Bus Station	11:10 AM	Milan	Lampugnano Bus Station	Economy	$37	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/8/2025 4:50:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 11:10:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 20m
FlixBus	5h 15m	6:25 AM	Pisa	Pietrasantina Bus Station	11:40 AM	Milan	San Donato Bus Station	Economy	$41	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/8/2025 6:25:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/8/2025 11:40:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 5h 15m
FlixBus	6h 0m	10:00 PM	Pisa	Pietrasantina Bus Station	4:00 AM	Milan	Lampugnano Bus Station	Economy	$49	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/8/2025 10:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/9/2025 4:00:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 6h 0m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	6h 50m	6:15 PM	Pisa	Pietrasantina Bus Station	1:05 AM	Milan	Lampugnano Bus Station		Economy	$31	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/10/2025 6:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/11/2025 1:05:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 6h 50m

Did you know that if you travel from Pisa to Milan via La Spezia, you can save more than $13? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  11:45 PM
  
  Pisa
  Pietrasantina Bus Station
  
  1:05 AM
  
  La Spezia
  Via Carducci Bus Stop
  
  0
  
  Economy
  
  $8
  
  A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/11/2025 11:45:00 PM to Via Carducci Bus Stop, La Spezia (Italy) arriving at 12/12/2025 1:05:00 AM. 50 Economy ticket for $8 per person are available. Travel duration is 1h 20m
- Distribusion
  
  4h 5m
  
  0
  
  2:45 AM
  
  La Spezia
  Via Carducci Bus Stop
  
  6:50 AM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Premium Economy
  
  $10
  
  A Bus from Distribusion goes from Via Carducci Bus Stop, La Spezia (Italy) at 12/12/2025 2:45:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 6:50:00 AM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 4h 5m
Travel time is 0h 15m longer, but you will save $13

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 15m	6:25 AM	Pisa	Pietrasantina Bus Station	11:40 AM	Milan	San Donato Bus Station	Economy	$23	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/11/2025 6:25:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/11/2025 11:40:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 5h 15m
FlixBus	6h 15m	4:45 PM	Pisa	Pietrasantina Bus Station	11:00 PM	Milan	San Donato Bus Station	Economy	$23	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/11/2025 4:45:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/11/2025 11:00:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 6h 15m
FlixBus	6h 50m	6:15 PM	Pisa	Pietrasantina Bus Station	1:05 AM	Milan	Lampugnano Bus Station	Economy	$23	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/11/2025 6:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 1:05:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 6h 50m
FlixBus	6h 0m	10:00 PM	Pisa	Pietrasantina Bus Station	4:00 AM	Milan	Lampugnano Bus Station	Economy	$23	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/11/2025 10:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 4:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 6h 0m
FlixBus	5h 15m	1:40 PM	Pisa	Pietrasantina Bus Station	6:55 PM	Milan	Lampugnano Bus Station	Economy	$24	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/11/2025 1:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/11/2025 6:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 5h 15m

Did you know that if you travel from Pisa to Milan via La Spezia, you can save more than $5? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  11:45 PM
  
  Pisa
  Pietrasantina Bus Station
  
  1:05 AM
  
  La Spezia
  Via Carducci Bus Stop
  
  0
  
  Economy
  
  $8
  
  A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 12/11/2025 11:45:00 PM to Via Carducci Bus Stop, La Spezia (Italy) arriving at 12/12/2025 1:05:00 AM. 50 Economy ticket for $8 per person are available. Travel duration is 1h 20m
- Distribusion
  
  4h 5m
  
  0
  
  2:45 AM
  
  La Spezia
  Via Carducci Bus Stop
  
  6:50 AM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Premium Economy
  
  $10
  
  A Bus from Distribusion goes from Via Carducci Bus Stop, La Spezia (Italy) at 12/12/2025 2:45:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 6:50:00 AM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 4h 5m
Travel time is 1h 50m longer, but you will save $5

Best Price Offer: The price for the cheapest bus from Pisa to Milan is $22 on 12/3/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Pisa and Milan

See here how frequent the connections between Pisa and Milan are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Pisa to Milan. Wednesday has instead the fewest connections, with only 1 daily coaches between Pisa and Milan.

The busiest time of the day is the Afternoon, with 15 buses from Pisa to Milan, while Morning sees the fewest connections between Pisa and Milan, with 5 offers.

Facts about the bus from Pisa to Milan

Compare all providers like FlixBus that travel 6 times every day by bus from Pisa to Milan in one click! Book your bus ticket from Pisa to Milan starting from $22!

Cheapest Bus	$22
Fastest Bus	5h 0m
Earliest Bus	4:50 AM
Latest Bus	10:00 PM
Daily Bus Routes	6 Ø
Distance	134.5 miles
Bus Companies	FlixBus

Cheapest bus connections from Pisa to Milan

Every day, 6 buses from 1 bus companies leave Pisa for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$27

Saturday 12/06

$30

Sunday 12/07

$33

Monday 12/08

$36

Tuesday 12/09

Wednesday 12/10

$31

Thursday 12/11

$23

Friday 12/12

$23

Saturday 12/13

$23

Sunday 12/14

$24

Monday 12/15

$23

Tuesday 12/16

Wednesday 12/17

$22

Thursday 12/18

$22

Friday 12/19

$24

Saturday 12/20

$27

Sunday 12/21

$33

Monday 12/22

$33

Tuesday 12/23

$29

Wednesday 12/24

$28

Thursday 12/25

$28

Friday 12/26

$26

Saturday 12/27

The cheapest time to travel from Pisa to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Pisa to Milan, for the next 30 days.

With a price starting from $22, Wednesday is the cheapest day for a bus from Pisa to Milan. Sunday instead is the most expensive day with prices starting from $24.

Night is the cheapest day time for bus tickets from Pisa to Milan, with $22. Afternoon is the most expensive time of the day with prices starting from $23.

How to save money travelling from Pisa to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pisa to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pisa to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Pisa to Milan are also emptier.

All bus stations and stops in Pisa and Milan

In the map below, you can see where to find all bus stations in Pisa and Milan.

Pietrasantina Bus Station

Via Pietrasantina

Central Bus Station

V.Brennero Porta A Lucca

Parking Aurelia

Ospedale Cisanello Bus Stop

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Pisa to Milan? Compare all modes of transports from Pisa to Milan.

Service and Comfort on the bus from Pisa to Milan

Want to know which seat classes are available on the buses from Pisa to Milan? Or which bus companies serve the route Pisa to Milan? Below you will find answers to your questions.

FAQs about the Pisa to Milan bus

How much does a Pisa Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $22 and takes 5h 15m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Pisa to Milan?

This route is offered by 1 companies with a range of ticket prices between $22 and $72. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Pisa to Milan each day?

Every day, the Pisa to Milan bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Pisa to Milan take?

The fastest bus from Pisa to Milan is offered by FlixBus and takes 5h 0m. Bus tickets for this connection cost $27. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Pisa to Milan?

The earliest bus arriving in Milan from Pisa starts at 4:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Pisa to Milan?

The latest bus trip departing from Pisa for Milan starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Pisa Milan route?

When traveling by bus from Pisa to Milan, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Pisa and Milan?

You can check all the direct connections between Pisa and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Pisa to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Pisa Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Pisa Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pisa to Milan on your planned travel date.

Available seat classes which are offered on the bus route Pisa to Milan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pisa and to Milan

Here’s an overview of the most popular bus routes to Pisa and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!