Bus Rome to Luxembourg City: Compare prices and save money

Compare all timetables for the bus from Rome to Luxembourg City

Here is a selection of the cheapest bus trips from the schedule from Rome to Luxembourg City from various bus operators like FlixBus for the next days.

today

$128

tomorrow

$142

Sunday

$157

Monday

$140

Tuesday

$156

Wednesday

$133

Thursday

$132

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 55m	11:35 PM	Rome	Anagnina Bus Station	3:30 AM	Luxembourg City	P+R Bouillon	Economy	$128	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 11:35:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/21/2025 3:30:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 27h 55m
FlixBus	25h 40m	1:05 PM	Rome	Anagnina Bus Station	2:45 PM	Luxembourg City	P+R Bouillon	Economy	$135	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 1:05:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/20/2025 2:45:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 25h 40m
FlixBus	26h 25m	11:50 PM	Rome	Tiburtina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$136	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 11:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/21/2025 2:15:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 26h 25m
FlixBus	28h 25m	11:50 PM	Rome	Tiburtina Bus Station	4:15 AM	Luxembourg City	P+R Bouillon	Economy	$140	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 11:50:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/21/2025 4:15:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 28h 25m
FlixBus	20h 35m	10:40 AM	Rome	Tiburtina Bus Station	7:15 AM	Luxembourg City	P+R Bouillon	Economy	$143	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 10:40:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/20/2025 7:15:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 20h 35m

Did you know that if you travel from Rome to Luxembourg City via Zurich, you can save more than $35? You can find the corresponding connections below.
- Distribusion
  
  28h 0m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Bus Station
  
  12:15 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 10:15:00 PM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/21/2025 12:15:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 14h 0m
- FlixBus
  
  6h 15m
  
  0
  
  8:00 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  2:15 AM
  
  Luxembourg City
  Central Bus Station
  
  0
  
  Economy
  
  $58
  
  A Bus from FlixBus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/21/2025 8:00:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/22/2025 2:15:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 6h 15m
Travel time is 7h 25m longer, but you will save $35

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	26h 40m	11:35 PM	Rome	Anagnina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$142	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/20/2025 11:35:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/22/2025 2:15:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 26h 40m
FlixBus	26h 25m	11:50 PM	Rome	Tiburtina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$148	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 11:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/22/2025 2:15:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 26h 25m
FlixBus	19h 20m	10:10 AM	Rome	Tiburtina Bus Station	5:30 AM	Luxembourg City	P+R Bouillon	Economy	$152	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 10:10:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/21/2025 5:30:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 19h 20m
FlixBus	20h 35m	10:40 AM	Rome	Tiburtina Bus Station	7:15 AM	Luxembourg City	P+R Bouillon	Economy	$152	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 10:40:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/21/2025 7:15:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 20h 35m
FlixBus	27h 55m	11:35 PM	Rome	Anagnina Bus Station	3:30 AM	Luxembourg City	P+R Bouillon	Economy	$156	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/20/2025 11:35:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/22/2025 3:30:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 27h 55m

Did you know that if you travel from Rome to Luxembourg City via Zurich, you can save more than $70? You can find the corresponding connections below.
- INFOBUS
  
  27h 45m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Bus Station
  
  12:15 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $40
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:15:00 PM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 12:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 14h 0m
- BlaBlaCar Bus
  
  6h 10m
  
  0
  
  7:50 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  2:00 AM
  
  Luxembourg City
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 7:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:00:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 10m
Travel time is 8h 25m longer, but you will save $70

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	26h 40m	11:35 PM	Rome	Anagnina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$157	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 11:35:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:15:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 26h 40m
FlixBus	19h 20m	10:10 AM	Rome	Tiburtina Bus Station	5:30 AM	Luxembourg City	P+R Bouillon	Economy	$160	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:10:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/22/2025 5:30:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 19h 20m
FlixBus	20h 35m	10:40 AM	Rome	Tiburtina Bus Station	7:15 AM	Luxembourg City	P+R Bouillon	Economy	$160	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:40:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/22/2025 7:15:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 20h 35m
FlixBus	26h 25m	11:50 PM	Rome	Tiburtina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$165	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 11:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:15:00 AM. 50 Economy ticket for $165 per person are available. Travel duration is 26h 25m
FlixBus	27h 55m	11:35 PM	Rome	Anagnina Bus Station	3:30 AM	Luxembourg City	P+R Bouillon	Economy	$168	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 11:35:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/23/2025 3:30:00 AM. 50 Economy ticket for $168 per person are available. Travel duration is 27h 55m

Did you know that if you travel from Rome to Luxembourg City via Zurich, you can save more than $85? You can find the corresponding connections below.
- INFOBUS
  
  27h 45m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Bus Station
  
  12:15 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $40
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:15:00 PM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 12:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 14h 0m
- BlaBlaCar Bus
  
  6h 10m
  
  0
  
  7:50 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  2:00 AM
  
  Luxembourg City
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 7:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:00:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 10m
Travel time is 8h 25m longer, but you will save $85

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 0m	1:05 PM	Rome	Anagnina Bus Station	4:05 PM	Luxembourg City	P+R Bouillon	Economy	$140	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 1:05:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/23/2025 4:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 27h 0m
FlixBus	28h 0m	12:15 AM	Rome	Tiburtina Bus Station	4:15 AM	Luxembourg City	P+R Bouillon	Economy	$145	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 12:15:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/23/2025 4:15:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 28h 0m
FlixBus	24h 35m	1:40 AM	Rome	Tiburtina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$146	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 1:40:00 AM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:15:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 24h 35m
FlixBus	20h 5m	9:25 AM	Rome	Tiburtina Bus Station	5:30 AM	Luxembourg City	P+R Bouillon	Economy	$149	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 9:25:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/23/2025 5:30:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 20h 5m
FlixBus	26h 25m	11:50 PM	Rome	Tiburtina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$153	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 11:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/24/2025 2:15:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 26h 25m

Did you know that if you travel from Rome to Luxembourg City via Zurich, you can save more than $68? You can find the corresponding connections below.
- INFOBUS
  
  27h 45m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Bus Station
  
  12:15 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $40
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:15:00 PM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 12:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 14h 0m
- BlaBlaCar Bus
  
  6h 10m
  
  0
  
  7:50 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  2:00 AM
  
  Luxembourg City
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 7:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:00:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 10m
Travel time is 7h 40m longer, but you will save $68

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 35m	1:40 AM	Rome	Tiburtina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$156	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:40:00 AM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/24/2025 2:15:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 24h 35m
FlixBus	27h 0m	1:05 PM	Rome	Anagnina Bus Station	4:05 PM	Luxembourg City	P+R Bouillon	Economy	$160	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/23/2025 1:05:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/24/2025 4:05:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 27h 0m
FlixBus	26h 25m	11:50 PM	Rome	Tiburtina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$163	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 11:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/25/2025 2:15:00 AM. 50 Economy ticket for $163 per person are available. Travel duration is 26h 25m
FlixBus	20h 5m	9:25 AM	Rome	Tiburtina Bus Station	5:30 AM	Luxembourg City	P+R Bouillon	Economy	$165	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 9:25:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/24/2025 5:30:00 AM. 50 Economy ticket for $165 per person are available. Travel duration is 20h 5m
FlixBus	20h 40m	8:30 AM	Rome	Tiburtina Bus Station	5:10 AM	Luxembourg City	P+R Bouillon	Economy	$186	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 8:30:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/24/2025 5:10:00 AM. 50 Economy ticket for $186 per person are available. Travel duration is 20h 40m

Did you know that if you travel from Rome to Luxembourg City via Zurich, you can save more than $84? You can find the corresponding connections below.
- INFOBUS
  
  27h 45m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Bus Station
  
  12:15 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $40
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:15:00 PM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 12:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 14h 0m
- BlaBlaCar Bus
  
  6h 10m
  
  0
  
  7:50 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  2:00 AM
  
  Luxembourg City
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 7:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:00:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 10m
Travel time is 7h 40m longer, but you will save $84

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 55m	11:35 PM	Rome	Anagnina Bus Station	3:30 AM	Luxembourg City	P+R Bouillon	Economy	$133	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 11:35:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/26/2025 3:30:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 27h 55m
FlixBus	26h 40m	11:35 PM	Rome	Anagnina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$133	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 11:35:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/26/2025 2:15:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 26h 40m
FlixBus	28h 25m	11:50 PM	Rome	Tiburtina Bus Station	4:15 AM	Luxembourg City	P+R Bouillon	Economy	$136	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 11:50:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/26/2025 4:15:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 28h 25m
FlixBus	27h 0m	1:05 PM	Rome	Anagnina Bus Station	4:05 PM	Luxembourg City	P+R Bouillon	Economy	$137	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 1:05:00 PM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/25/2025 4:05:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 27h 0m
FlixBus	28h 20m	8:50 AM	Rome	Tiburtina Bus Station	1:10 PM	Luxembourg City	P+R Bouillon	Economy	$145	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 8:50:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/25/2025 1:10:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 28h 20m

Did you know that if you travel from Rome to Luxembourg City via Zurich, you can save more than $61? You can find the corresponding connections below.
- INFOBUS
  
  27h 45m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Bus Station
  
  12:15 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $40
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:15:00 PM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 12:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 14h 0m
- BlaBlaCar Bus
  
  6h 10m
  
  0
  
  7:50 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  2:00 AM
  
  Luxembourg City
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 7:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:00:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 10m
Travel time is 1h 5m longer, but you will save $61

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 5m	10:10 AM	Rome	Tiburtina Bus Station	7:15 AM	Luxembourg City	P+R Bouillon	Economy	$132	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/25/2025 10:10:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/26/2025 7:15:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 21h 5m
FlixBus	26h 40m	11:35 PM	Rome	Anagnina Bus Station	2:15 AM	Luxembourg City	Central Bus Station	Economy	$132	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/25/2025 11:35:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/27/2025 2:15:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 26h 40m
FlixBus	27h 35m	11:10 AM	Rome	Anagnina Bus Station	2:45 PM	Luxembourg City	P+R Bouillon	Economy	$133	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/25/2025 11:10:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/26/2025 2:45:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 27h 35m
FlixBus	28h 0m	12:15 AM	Rome	Tiburtina Bus Station	4:15 AM	Luxembourg City	P+R Bouillon	Economy	$136	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/25/2025 12:15:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/26/2025 4:15:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 28h 0m
FlixBus	20h 40m	8:30 AM	Rome	Tiburtina Bus Station	5:10 AM	Luxembourg City	P+R Bouillon	Economy	$138	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/25/2025 8:30:00 AM to P+R Bouillon, Luxembourg City (Luxembourg) arriving at 12/26/2025 5:10:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 20h 40m

Did you know that if you travel from Rome to Luxembourg City via Zurich, you can save more than $60? You can find the corresponding connections below.
- INFOBUS
  
  27h 45m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Bus Station
  
  12:15 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $40
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 10:15:00 PM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 12:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 14h 0m
- BlaBlaCar Bus
  
  6h 10m
  
  0
  
  7:50 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  2:00 AM
  
  Luxembourg City
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 7:50:00 PM to Central Bus Station, Luxembourg City (Luxembourg) arriving at 12/23/2025 2:00:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 10m
Travel time is 7h 5m longer, but you will save $60

Best Price Offer: The price for the cheapest bus from Rome to Luxembourg City is $70 on 12/16/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Rome and Luxembourg City

See here how frequent the connections between Rome and Luxembourg City are, during different times and days of the week.

Sunday is the busiest day, with more than 11 daily buses from Rome to Luxembourg City. Tuesday has instead the fewest connections, with only 8 daily coaches between Rome and Luxembourg City.

The busiest time of the day is the Evening, with 29 buses from Rome to Luxembourg City, while Night sees the fewest connections between Rome and Luxembourg City, with 8 offers.

Facts about the bus from Rome to Luxembourg City

Compare all providers like FlixBus that travel 9 times every day by bus from Rome to Luxembourg City in one click! Book your bus ticket from Rome to Luxembourg City starting from $70!

Cheapest Bus	$70
Fastest Bus	19h 20m
Earliest Bus	10:40 AM
Latest Bus	11:50 PM
Daily Bus Routes	9 Ø
Distance	614.5 miles
Bus Companies	FlixBus

Cheapest bus connections from Rome to Luxembourg City

Every day, 9 buses from 1 bus companies leave Rome for Luxembourg City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$128

Saturday 12/20

$142

Sunday 12/21

$157

Monday 12/22

$140

Tuesday 12/23

$156

Wednesday 12/24

$133

Thursday 12/25

$132

Friday 12/26

$156

Saturday 12/27

$167

Sunday 12/28

$176

Monday 12/29

$152

Tuesday 12/30

$162

Wednesday 12/31

$146

Thursday 01/01

$176

Friday 01/02

$194

Saturday 01/03

$174

Sunday 01/04

$152

Monday 01/05

$109

Tuesday 01/06

$109

Wednesday 01/07

$100

Thursday 01/08

$83

Friday 01/09

$76

Saturday 01/10

The cheapest time to travel from Rome to Luxembourg City

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Luxembourg City, for the next 30 days.

With a price starting from $61, Wednesday is the cheapest day for a bus from Rome to Luxembourg City. Thursday instead is the most expensive day with prices starting from $83.

Night is the cheapest day time for bus tickets from Rome to Luxembourg City, with $61. Afternoon is the most expensive time of the day with prices starting from $135.

How to save money travelling from Rome to Luxembourg City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Luxembourg City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Luxembourg City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Luxembourg City are also emptier.

All bus stations and stops in Rome and Luxembourg City

In the map below, you can see where to find all bus stations in Rome and Luxembourg City.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Central Bus Station

Place de la Gare

P+R Bouillon

Rue de Bouillon

Bus Stop

Rue Mercier 2

Gasperich

Rue In Bouler 1

Kirchberg (Alphonse Weicker)

Rue Alphonse Weicker 4

Service and Comfort on the bus from Rome to Luxembourg City

Want to know which seat classes are available on the buses from Rome to Luxembourg City? Or which bus companies serve the route Rome to Luxembourg City? Below you will find answers to your questions.

FAQs about the Rome to Luxembourg City bus

How much does a Rome Luxembourg City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $70 and takes 27h 55m to reach Luxembourg City. Compare offers to save money!

How much could I save by comparing buses from Rome to Luxembourg City?

This route is offered by 1 companies with a range of ticket prices between $70 and $221. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Luxembourg City.

On average, how many connections are available from Rome to Luxembourg City each day?

Every day, the Rome to Luxembourg City bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Luxembourg City take?

The fastest bus from Rome to Luxembourg City is offered by FlixBus and takes 19h 20m. Bus tickets for this connection cost $152. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Luxembourg City?

The earliest bus arriving in Luxembourg City from Rome starts at 10:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Luxembourg City?

The latest bus trip departing from Rome for Luxembourg City starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Luxembourg City route?

When traveling by bus from Rome to Luxembourg City, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Luxembourg City?

You can check all the direct connections between Rome and Luxembourg City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Luxembourg City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Luxembourg City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Luxembourg City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Luxembourg City on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Luxembourg City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Rome and Luxembourg City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Luxembourg City?

Prices and availability for 9 trips between Rome and Luxembourg City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Luxembourg City

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Luxembourg City

Here’s an overview of the most popular bus routes to Rome and to Luxembourg City. Simply click on the connection of your choice, and you will find all the details about your bus route!