Compare all timetables for the bus from San Diego to Chicago
Cheapest bus trips today
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FlixBus56h 30m012:00 PMSan DiegoOld Town Transit Center8:30 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/23/2025 12:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/25/2025 8:30:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 56h 30m
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Greyhound US60h 45m07:35 PMSan DiegoOld Town Transit Center8:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/23/2025 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2025 8:20:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 60h 45m
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FlixBus67h 55m012:00 PMSan DiegoSeaport Village7:55 AMChicagoCanal & Van Buren0EconomyA Bus from FlixBus goes from Seaport Village, San Diego (USA) at 6/23/2025 12:00:00 PM to Canal & Van Buren, Chicago (USA) arriving at 6/26/2025 7:55:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 67h 55m
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FlixBus67h 35m012:20 PMSan DiegoBalboa Park7:55 AMChicagoCanal & Van Buren0EconomyA Bus from FlixBus goes from Balboa Park, San Diego (USA) at 6/23/2025 12:20:00 PM to Canal & Van Buren, Chicago (USA) arriving at 6/26/2025 7:55:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 67h 35m
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Greyhound US60h 20m07:35 PMSan DiegoOld Town Transit Center7:55 AMChicagoCanal & Van Buren0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/23/2025 7:35:00 PM to Canal & Van Buren, Chicago (USA) arriving at 6/26/2025 7:55:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 60h 20m
Cheapest bus trips tomorrow
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Greyhound US56h 55m07:15 AMSan DiegoOld Town Transit Center4:10 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/24/2025 7:15:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2025 4:10:00 PM. 50 Economy ticket for $327 per person are available. Travel duration is 56h 55m
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FlixBus56h 35m07:35 AMSan DiegoOld Town Transit Center4:10 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/24/2025 7:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2025 4:10:00 PM. 50 Economy ticket for $334 per person are available. Travel duration is 56h 35m
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FlixBus56h 15m07:55 AMSan DiegoLa Jolla Village4:10 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/24/2025 7:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2025 4:10:00 PM. 50 Economy ticket for $337 per person are available. Travel duration is 56h 15m
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Greyhound US60h 45m07:35 PMSan DiegoOld Town Transit Center8:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/24/2025 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2025 8:20:00 AM. 50 Economy ticket for $353 per person are available. Travel duration is 60h 45m
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Greyhound US55h 50m02:00 PMSan DiegoOld Town Transit Center9:50 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/24/2025 2:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2025 9:50:00 PM. 50 Economy ticket for $356 per person are available. Travel duration is 55h 50m
Cheapest bus trips Thursday
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FlixBus56h 35m08:10 AMSan DiegoOld Town Transit Center4:45 PMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/26/2025 8:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/28/2025 4:45:00 PM. 50 Economy ticket for $333 per person are available. Travel duration is 56h 35m
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FlixBus56h 5m08:40 AMSan DiegoLa Jolla Village4:45 PMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/26/2025 8:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/28/2025 4:45:00 PM. 50 Economy ticket for $333 per person are available. Travel duration is 56h 5m
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Greyhound US54h 45m010:00 AMSan DiegoOld Town Transit Center4:45 PMChicagoDowntown Bus Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/26/2025 10:00:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/28/2025 4:45:00 PM. 50 Economy ticket for $333 per person are available. Travel duration is 54h 45m
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FlixBus57h 25m06:15 PMSan DiegoSDSU Transit Center3:40 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from SDSU Transit Center, San Diego (USA) at 6/26/2025 6:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/29/2025 3:40:00 AM. 50 Economy ticket for $351 per person are available. Travel duration is 57h 25m
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Greyhound US56h 5m07:35 PMSan DiegoOld Town Transit Center3:40 AMChicagoDowntown Bus Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/26/2025 7:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/29/2025 3:40:00 AM. 50 Economy ticket for $362 per person are available. Travel duration is 56h 5m
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Busbud79h 45m09:00 AMSan DiegoOld Town Transit Center10:59 PMGlendale, AZCentral Bus Station0EconomyA Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 6/26/2025 9:00:00 AM to Central Bus Station, Glendale, AZ (USA) arriving at 6/26/2025 10:59:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 59m
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FlixBus41h 40m011:05 PMGlendale, AZCentral Bus Station4:45 PMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, Glendale, AZ (USA) at 6/27/2025 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/29/2025 4:45:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 41h 40m
Waiting Time 24h 6m -
Cheapest bus trips Friday
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Greyhound US55h 50m02:00 PMSan DiegoOld Town Transit Center9:50 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/27/2025 2:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/29/2025 9:50:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 55h 50m
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FlixBus55h 10m09:00 AMSan DiegoOld Town Transit Center4:10 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/27/2025 9:00:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/29/2025 4:10:00 PM. 50 Economy ticket for $213 per person are available. Travel duration is 55h 10m
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FlixBus61h 45m06:35 PMSan DiegoOld Town Transit Center8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/27/2025 6:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/30/2025 8:20:00 AM. 50 Economy ticket for $214 per person are available. Travel duration is 61h 45m
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FlixBus61h 20m07:00 PMSan DiegoLa Jolla Village8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/27/2025 7:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/30/2025 8:20:00 AM. 50 Economy ticket for $214 per person are available. Travel duration is 61h 20m
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Greyhound US60h 45m07:35 PMSan DiegoOld Town Transit Center8:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/27/2025 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/30/2025 8:20:00 AM. 50 Economy ticket for $214 per person are available. Travel duration is 60h 45m
Cheapest bus trips Sunday
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FlixBus61h 45m06:35 PMSan DiegoOld Town Transit Center8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/29/2025 6:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/2/2025 8:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 61h 45m
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FlixBus61h 20m07:00 PMSan DiegoLa Jolla Village8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/29/2025 7:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/2/2025 8:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 61h 20m
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FlixBus62h 5m06:15 PMSan DiegoSDSU Transit Center8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from SDSU Transit Center, San Diego (USA) at 6/29/2025 6:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/2/2025 8:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 62h 5m
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Greyhound US54h 0m010:00 AMSan DiegoOld Town Transit Center4:00 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/29/2025 10:00:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/1/2025 4:00:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 54h 0m
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Greyhound US60h 45m07:35 PMSan DiegoOld Town Transit Center8:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/29/2025 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/2/2025 8:20:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 60h 45m
Frequency of bus connections between San Diego and Chicago
Facts about the bus from San Diego to Chicago
Compare all providers like FlixBus and Greyhound US that travel 16 times every day by bus from San Diego to Chicago in one click! Book your bus ticket from San Diego to Chicago starting from $116!
Cheapest Bus | $116 |
Fastest Bus | 54h 0m |
Earliest Bus | 8:10 AM |
Latest Bus | 7:35 PM |
Daily Bus Routes | 16 Ø |
Distance | 1,730.9 miles |
Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from San Diego to Chicago
Every day, 16 buses from 2 bus companies leave San Diego for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/23/2025 and for the following days.
The cheapest time to travel from San Diego to Chicago
How to save money travelling from San Diego to Chicago
Book the ticket from San Diego to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Chicago, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Chicago are also emptier.All bus stations and stops in San Diego and Chicago
In the map below, you can see where to find all bus stations in San Diego and Chicago.
Compare the bus with other modes of transport
Service and Comfort on the bus from San Diego to Chicago
FAQs about the San Diego to Chicago bus
How much does a San Diego Chicago bus trip cost?
How much could I save by comparing buses from San Diego to Chicago?
On average, how many connections are available from San Diego to Chicago each day?
How long does a bus journey from San Diego to Chicago take?
What time is the first bus from San Diego to Chicago?
What time is the last bus from San Diego to Chicago?
Which bus companies operate the San Diego Chicago route?
Is there a direct bus between San Diego and Chicago?
What can I take with me on the San Diego to Chicago bus route?
What equipment is available for the San Diego Chicago bus route?
Available seat classes which are offered on the bus route San Diego to Chicago
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to San Diego and to Chicago
- Bus Routes to San Diego
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- Buses Atlanta, GA to San Diego
- Bus Burbank, CA - San Diego
- Bus to San Diego from Calexico, CA
- Bus to San Diego from Denver
- Bus from Downey, CA to San Diego
- Bus El Centro, CA - San Diego
- From El Paso, TX to San Diego bus
- Buses to San Diego from Indianapolis
- Buses to San Diego from Mexicali
- Buses from Modesto, CA to San Diego
- Bus from Olympia, WA to San Diego
- Buses Ontario, CA - San Diego
- Bus to San Diego from Perris, CA
- Bus Phoenix, AZ - San Diego
- Bus from Riverside, CA to San Diego
- Buses from Sacramento to San Diego
- Bus from San Bernardino, CA to San Diego
- Bus San Jose, CA to San Diego
- Bus to San Diego from Tucson, AZ
- Bus Routes to Chicago
- From Bloomington, IL to Chicago bus
- Bloomington, IN to Chicago bus
- Bus Cincinnati - Chicago
- From Cleveland to Chicago bus
- Bus Dallas to Chicago
- From Gary, IN to Chicago bus
- Indianapolis to Chicago bus
- Iowa City, IA to Chicago bus
- Bus to Chicago from Lansing, MI
- Bus from Los Angeles to Chicago
- Buses from Louisville, KY to Chicago
- Bus Madison, WI - Chicago
- New York to Chicago bus
- Bus Niagara Falls, ON - Chicago
- Bus Orlando, FL to Chicago
- Bus from Philadelphia to Chicago
- Buses Phoenix, AZ - Chicago
- Buses Richmond, VA to Chicago
- Bus Seattle, WA - Chicago
- Buses Springfield, IL to Chicago