Compare all timetables for the bus from San Diego to Chicago
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 55h 45m | 7:35 PM | San Diego | Old Town Transit Center | 5:20 AM | Chicago | 95th Red Line Station | Economy | $139 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/8/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/11/2026 5:20:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 55h 45m
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| FlixBus | 51h 25m | 1:10 PM | San Diego | Seaport Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $140 |
A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/8/2026 1:10:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/10/2026 6:35:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 51h 25m
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| Greyhound US | 54h 45m | 9:50 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $140 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/8/2026 9:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/10/2026 6:35:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 54h 45m
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| FlixBus | 55h 10m | 9:25 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $141 |
A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/8/2026 9:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/10/2026 6:35:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 55h 10m
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| FlixBus | 51h 0m | 1:35 PM | San Diego | La Jolla Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $150 |
A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/8/2026 1:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/10/2026 6:35:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 51h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 51h 25m | 1:10 PM | San Diego | Seaport Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $142 |
A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/9/2026 1:10:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/11/2026 6:35:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 51h 25m
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| Greyhound US | 54h 45m | 9:50 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $143 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/9/2026 9:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/11/2026 6:35:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 54h 45m
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| Greyhound US | 55h 45m | 7:35 PM | San Diego | Old Town Transit Center | 5:20 AM | Chicago | 95th Red Line Station | Economy | $143 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/9/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/12/2026 5:20:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 55h 45m
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| FlixBus | 55h 10m | 9:25 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $144 |
A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/9/2026 9:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/11/2026 6:35:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 55h 10m
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| Greyhound US | 58h 25m | 7:35 PM | San Diego | Old Town Transit Center | 8:00 AM | Chicago | Canal & Van Buren | Economy | $188 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/9/2026 7:35:00 PM to Canal & Van Buren, Chicago (USA) arriving at 5/12/2026 8:00:00 AM. 50 Economy ticket for $188 per person are available. Travel duration is 58h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 59h 25m | 3:55 PM | San Diego | Old Town Transit Center | 5:20 AM | Chicago | 95th Red Line Station | Economy | $130 |
A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/10/2026 3:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/13/2026 5:20:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 59h 25m
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| Greyhound US | 55h 45m | 7:35 PM | San Diego | Old Town Transit Center | 5:20 AM | Chicago | 95th Red Line Station | Economy | $131 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/10/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/13/2026 5:20:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 55h 45m
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| FlixBus | 52h 20m | 12:15 PM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $132 |
A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/10/2026 12:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/12/2026 6:35:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 52h 20m
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| FlixBus | 51h 25m | 1:10 PM | San Diego | Seaport Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $132 |
A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/10/2026 1:10:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/12/2026 6:35:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 51h 25m
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| Greyhound US | 54h 45m | 9:50 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $134 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/10/2026 9:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/12/2026 6:35:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 54h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 51h 25m | 1:10 PM | San Diego | Seaport Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $144 |
A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/11/2026 1:10:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/13/2026 6:35:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 51h 25m
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| Greyhound US | 54h 45m | 9:50 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $144 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/11/2026 9:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/13/2026 6:35:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 54h 45m
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| FlixBus | 55h 10m | 9:25 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $146 |
A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/11/2026 9:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/13/2026 6:35:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 55h 10m
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| FlixBus | 51h 0m | 1:35 PM | San Diego | La Jolla Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $149 |
A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/11/2026 1:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/13/2026 6:35:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 51h 0m
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| Greyhound US | 52h 15m | 9:50 AM | San Diego | Old Town Transit Center | 4:05 PM | Chicago | Downtown Bus Station | Economy | $179 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/11/2026 9:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 5/13/2026 4:05:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 52h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 55h 45m | 7:35 PM | San Diego | Old Town Transit Center | 5:20 AM | Chicago | 95th Red Line Station | Economy | $156 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/12/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/15/2026 5:20:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 55h 45m
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| FlixBus | 51h 25m | 1:10 PM | San Diego | Seaport Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $157 |
A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/12/2026 1:10:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/14/2026 6:35:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 51h 25m
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| Greyhound US | 57h 50m | 6:45 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $158 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/12/2026 6:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/14/2026 6:35:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 57h 50m
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| FlixBus | 55h 10m | 9:25 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $159 |
A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/12/2026 9:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/14/2026 6:35:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 55h 10m
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| FlixBus | 51h 0m | 1:35 PM | San Diego | La Jolla Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $161 |
A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/12/2026 1:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/14/2026 6:35:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 51h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 51h 0m | 1:35 PM | San Diego | La Jolla Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $149 |
A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/13/2026 1:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/15/2026 6:35:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 51h 0m
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| Greyhound US | 55h 45m | 7:35 PM | San Diego | Old Town Transit Center | 5:20 AM | Chicago | 95th Red Line Station | Economy | $150 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/13/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/16/2026 5:20:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 55h 45m
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| FlixBus | 51h 25m | 1:10 PM | San Diego | Seaport Village | 6:35 PM | Chicago | 95th Red Line Station | Economy | $150 |
A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/13/2026 1:10:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/15/2026 6:35:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 51h 25m
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| FlixBus | 55h 10m | 9:25 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $151 |
A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/13/2026 9:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/15/2026 6:35:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 55h 10m
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| Greyhound US | 57h 50m | 6:45 AM | San Diego | Old Town Transit Center | 6:35 PM | Chicago | 95th Red Line Station | Economy | $153 |
A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/13/2026 6:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/15/2026 6:35:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 57h 50m
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Best Price Offer: The price for the cheapest bus from San Diego to Chicago is $118 on 5/27/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between San Diego and Chicago
Facts about the bus from San Diego to Chicago
Compare all providers like FlixBus and Greyhound US that travel 21 times every day by bus from San Diego to Chicago in one click! Book your bus ticket from San Diego to Chicago starting from $118!
| Cheapest Bus | $118 |
| Fastest Bus | 50h 50m |
| Earliest Bus | 7:35 AM |
| Latest Bus | 7:35 PM |
| Daily Bus Routes | 21 Ø |
| Distance | 1,730.9 miles |
| Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from San Diego to Chicago
Every day, 21 buses from 2 bus companies leave San Diego for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.
The cheapest time to travel from San Diego to Chicago
How to save money travelling from San Diego to Chicago
Book the ticket from San Diego to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Chicago, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Chicago are also emptier.Beloved bus companies from San Diego to Chicago
FlixBus from San Diego to Chicago
Here you will find the key facts about the FlixBus bus route San Diego to Chicago:
| Cheapest Price | $130 |
| Fastest Bus | 50h 50m |
| Earliest Bus | 7:35 AM |
| Last Bus | 1:35 PM |
| Daily Connections | 14 Ø |
| Found on | 4/13/2026 |
All bus stations and stops in San Diego and Chicago
In the map below, you can see where to find all bus stations in San Diego and Chicago.
Service and Comfort on the bus from San Diego to Chicago
FAQs about the San Diego to Chicago bus
How much does a San Diego Chicago bus trip cost?
How much could I save by comparing buses from San Diego to Chicago?
On average, how many connections are available from San Diego to Chicago each day?
How long does a bus journey from San Diego to Chicago take?
What time is the first bus from San Diego to Chicago?
What time is the last bus from San Diego to Chicago?
Which bus companies operate the San Diego Chicago route?
Is there a direct bus between San Diego and Chicago?
What can I take with me on the San Diego to Chicago bus route?
What equipment is available for the San Diego Chicago bus route?
How does CheckMyBus find the best bus deals from San Diego to Chicago?
How does CheckMyBus technology work for trips from San Diego to Chicago?
Available seat classes which are offered on the bus route San Diego to Chicago
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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