Bus from San Diego to Chicago from $141

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Compare all timetables for the bus from San Diego to Chicago

Here is a selection of the cheapest bus trips from the schedule from San Diego to Chicago from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
$235
Thursday
Friday
Saturday
$142
Sunday
$167
Monday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 55h 10m 6:45 AM San Diego Old Town Transit Center 3:55 PM Chicago 95th Red Line Station  Economy $235
FlixBus 54h 20m 7:35 AM San Diego Old Town Transit Center 3:55 PM Chicago 95th Red Line Station  Economy $237
FlixBus 51h 0m 1:35 PM San Diego La Jolla Village 6:35 PM Chicago 95th Red Line Station  Economy $237
FlixBus 51h 25m 1:10 PM San Diego Seaport Village 6:35 PM Chicago 95th Red Line Station  Economy $237
Greyhound US 55h 45m 7:35 PM San Diego Old Town Transit Center 5:20 AM Chicago 95th Red Line Station  Economy $238

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 59h 25m 3:55 PM San Diego Old Town Transit Center 5:20 AM Chicago 95th Red Line Station  Economy $142
FlixBus 54h 20m 7:35 AM San Diego Old Town Transit Center 3:55 PM Chicago 95th Red Line Station  Economy $143
Greyhound US 51h 55m 10:00 AM San Diego Old Town Transit Center 3:55 PM Chicago 95th Red Line Station  Economy $144
FlixBus 52h 20m 12:15 PM San Diego Old Town Transit Center 6:35 PM Chicago 95th Red Line Station  Economy $144
Greyhound US 55h 45m 7:35 PM San Diego Old Town Transit Center 5:20 AM Chicago 95th Red Line Station  Economy $145

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 52h 5m 9:50 AM San Diego Old Town Transit Center 3:55 PM Chicago 95th Red Line Station  Economy $167
FlixBus 59h 25m 3:55 PM San Diego Old Town Transit Center 5:20 AM Chicago 95th Red Line Station  Economy $168
FlixBus 51h 0m 1:35 PM San Diego La Jolla Village 6:35 PM Chicago 95th Red Line Station  Economy $168
FlixBus 59h 5m 4:15 PM San Diego La Jolla Village 5:20 AM Chicago 95th Red Line Station  Economy $168
Greyhound US 55h 45m 7:35 PM San Diego Old Town Transit Center 5:20 AM Chicago 95th Red Line Station  Economy $169

Best Price Offer: The price for the cheapest bus from San Diego to Chicago is $141 on 4/4/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between San Diego and Chicago

See here how frequent the connections between San Diego and Chicago are, during different times and days of the week.
Sunday is the busiest day, with more than 21 daily buses from San Diego to Chicago. Wednesday has instead the fewest connections, with only 7 daily coaches between San Diego and Chicago.
The busiest time of the day is the Afternoon, with 23 buses from San Diego to Chicago, while Evening sees the fewest connections between San Diego and Chicago, with 7 offers.

Facts about the bus from San Diego to Chicago

Compare all providers like FlixBus and Greyhound US that travel 14 times every day by bus from San Diego to Chicago in one click! Book your bus ticket from San Diego to Chicago starting from $141!

Cheapest Bus $141
Fastest Bus 50h 50m
Earliest Bus 6:45 AM
Latest Bus 7:35 PM
Daily Bus Routes 14 Ø
Distance 1,730.9 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from San Diego to Chicago

Every day, 14 buses from 2 bus companies leave San Diego for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/22
Monday 03/23
Tuesday 03/24
Wednesday 03/25
$235
Thursday 03/26
Friday 03/27
Saturday 03/28
$142
Sunday 03/29
$167
Monday 03/30
Tuesday 03/31
$163
Wednesday 04/01
Thursday 04/02
$156
Friday 04/03
Saturday 04/04
$141
Sunday 04/05
$171
Monday 04/06
$157
Tuesday 04/07
$181
Wednesday 04/08
$186
Thursday 04/09
$168
Friday 04/10
$164
Saturday 04/11
$161
Sunday 04/12
$148
Monday 04/13
$167
Tuesday 04/14
$162
Wednesday 04/15
$198
Thursday 04/16
$169
Friday 04/17
Saturday 04/18

The cheapest time to travel from San Diego to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Chicago, for the next 30 days.
With a price starting from $141, Saturday is the cheapest day for a bus from San Diego to Chicago. Wednesday instead is the most expensive day with prices starting from $186.
Afternoon is the cheapest day time for bus tickets from San Diego to Chicago, with $142. Evening is the most expensive time of the day with prices starting from $145.

How to save money travelling from San Diego to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Chicago are also emptier.

Beloved bus companies from San Diego to Chicago

These are the most booked bus companies between San Diego to Chicago from our users.

FlixBus from San Diego to Chicago

FlixBus

Here you will find the key facts about the FlixBus bus route San Diego to Chicago:

Cheapest Price $142
Fastest Bus 50h 50m
Earliest Bus 7:35 AM
Last Bus 4:15 PM
Daily Connections 9 Ø
Found on 2/27/2026

All bus stations and stops in San Diego and Chicago

In the map below, you can see where to find all bus stations in San Diego and Chicago.

Service and Comfort on the bus from San Diego to Chicago

Want to know which seat classes are available on the buses from San Diego to Chicago? Or which bus companies serve the route San Diego to Chicago? Below you will find answers to your questions.

FAQs about the San Diego to Chicago bus

How much does a San Diego Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $141 and takes 61h 25m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from San Diego to Chicago?

This route is offered by 2 companies with a range of ticket prices between $141 and $239. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from San Diego to Chicago each day?

Every day, the San Diego to Chicago bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Chicago take?

The fastest bus from San Diego to Chicago is offered by FlixBus and takes 50h 50m. Bus tickets for this connection cost $172. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Chicago?

The earliest bus arriving in Chicago from San Diego starts at 6:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Chicago?

The latest bus trip departing from San Diego for Chicago starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Chicago route?

When traveling by bus from San Diego to Chicago, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Chicago?

You can check all the direct connections between San Diego and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between San Diego and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to Chicago?

Prices and availability for 14 trips between San Diego and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Chicago

Here’s an overview of the most popular bus routes to San Diego and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus to San Diego from Escondido, CA Bus to San Diego from Escondido, CA
From Tijuana, BC to Chicago bus From Tijuana, BC to Chicago bus
Bus to Chicago from Queens Village, NY Bus to Chicago from Queens Village, NY
From Baton Rouge to Chicago bus From Baton Rouge to Chicago bus
From Toledo, OH to Chicago bus From Toledo, OH to Chicago bus
Popular Airport Shuttles to San Diego and to Chicago
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