Bus from San Diego to San Antonio, TX from $124

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Compare all timetables for the bus from San Diego to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from San Diego to San Antonio, TX from various bus operators like FlixBus or Greyhound US for the next days.

today
from $203
tomorrow
from $125
Monday
from $204
Tuesday
Wednesday
from $124
Thursday
from $128
Friday

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    34h 25m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $203
  • FlixBus
    40h 15m
    0
    7:35 AM
    San Diego
    Old Town Transit Center
    11:50 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $206
  • FlixBus
    36h 15m
    0
    12:10 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $208
  • FlixBus
    36h 35m
    0
    11:50 AM
    San Diego
    Seaport Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $208
  • Greyhound US
    37h 50m
    0
    10:00 AM
    San Diego
    Old Town Transit Center
    11:50 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $210
  • Did you know that if you travel from San Diego to San Antonio, TX via Calexico, CA, you can save more than $74? You can find the corresponding connections below.
    • FlixBus
      38h 25m
      0
      10:00 AM
      San Diego
      Old Town Transit Center
      12:35 PM
      Calexico, CA
      Bus Station
      0
      FlixBus
      Economy
      $32
      • Waiting Time 5h 20m
    • FlixBus
      30h 30m
      0
      5:55 PM
      Calexico, CA
      Bus Station
      12:25 AM
      San Antonio, TX
      Bus Station
      0
      FlixBus
      Economy
      $97
    Travel time is 4h 0m longer, but you will save $74

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    34h 25m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $125
  • FlixBus
    35h 45m
    0
    12:40 PM
    San Diego
    La Jolla Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $126
  • FlixBus
    36h 15m
    0
    12:10 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $128
  • FlixBus
    36h 35m
    0
    11:50 AM
    San Diego
    Seaport Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $128
  • Greyhound US
    37h 50m
    0
    10:00 AM
    San Diego
    Old Town Transit Center
    11:50 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $130

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    35h 45m
    0
    12:40 PM
    San Diego
    La Jolla Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $204
  • FlixBus
    36h 15m
    0
    12:10 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $206
  • FlixBus
    36h 35m
    0
    11:50 AM
    San Diego
    Seaport Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $206
  • Greyhound US
    34h 25m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $207
  • Greyhound US
    37h 50m
    0
    10:00 AM
    San Diego
    Old Town Transit Center
    11:50 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $213
  • Did you know that if you travel from San Diego to San Antonio, TX via Calexico, CA, you can save more than $75? You can find the corresponding connections below.
    • FlixBus
      38h 25m
      0
      10:00 AM
      San Diego
      Old Town Transit Center
      12:35 PM
      Calexico, CA
      Bus Station
      0
      FlixBus
      Economy
      $32
      • Waiting Time 5h 20m
    • FlixBus
      30h 30m
      0
      5:55 PM
      Calexico, CA
      Bus Station
      12:25 AM
      San Antonio, TX
      Bus Station
      0
      FlixBus
      Economy
      $97
    Travel time is 4h 0m longer, but you will save $75

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    36h 15m
    0
    12:10 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $124
  • FlixBus
    36h 35m
    0
    11:50 AM
    San Diego
    Seaport Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $124
  • Greyhound US
    34h 25m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $126
  • FlixBus
    35h 45m
    0
    12:40 PM
    San Diego
    La Jolla Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $127
  • Greyhound US
    41h 20m
    0
    7:35 PM
    San Diego
    Old Town Transit Center
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $179

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    36h 15m
    0
    12:10 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $128
  • FlixBus
    36h 35m
    0
    11:50 AM
    San Diego
    Seaport Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $128
  • Greyhound US
    34h 25m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $129
  • FlixBus
    35h 45m
    0
    12:40 PM
    San Diego
    La Jolla Village
    12:25 AM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $130
  • Greyhound US
    37h 50m
    0
    10:00 AM
    San Diego
    Old Town Transit Center
    11:50 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $132

Frequency of bus connections between San Diego and San Antonio, TX

See here how frequent the connections between San Diego and San Antonio, TX are, during different times and days of the week.
Saturday is the busiest day, with more than 17 daily buses from San Diego to San Antonio, TX. Wednesday has instead the fewest connections, with only 7 daily coaches between San Diego and San Antonio, TX.
The busiest time of the day is the Morning, with 22 buses from San Diego to San Antonio, TX, while Evening sees the fewest connections between San Diego and San Antonio, TX, with 15 offers.

Facts about the bus from San Diego to San Antonio, TX

Compare all providers like FlixBus and Greyhound US that travel 10 times every day by bus from San Diego to San Antonio, TX in one click! Book your bus ticket from San Diego to San Antonio, TX starting from $124!

Cheapest Bus $124
Fastest Bus 34h 25m
Earliest Bus 7:35 AM
Latest Bus 7:35 PM
Daily Bus Routes 10 Ø
Distance 1,126.5 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from San Diego to San Antonio, TX

Every day, 10 buses from 2 bus companies leave San Diego for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/28/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
Thursday 06/26
Friday 06/27
Saturday 06/28
$203
Sunday 06/29
$125
Monday 06/30
$204
Tuesday 07/01
Wednesday 07/02
$124
Thursday 07/03
$128
Friday 07/04
Saturday 07/05
$237
Sunday 07/06
$172
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
$138
Friday 07/11
Saturday 07/12
Sunday 07/13
Monday 07/14
Tuesday 07/15
Wednesday 07/16
Thursday 07/17
Friday 07/18
Saturday 07/19

The cheapest time to travel from San Diego to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to San Antonio, TX, for the next 30 days.
With a price starting from $124, Wednesday is the cheapest day for a bus from San Diego to San Antonio, TX. Monday instead is the most expensive day with prices starting from $204.
Morning is the cheapest day time for bus tickets from San Diego to San Antonio, TX, with $124. Evening is the most expensive time of the day with prices starting from $132.

How to save money travelling from San Diego to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to San Antonio, TX are also emptier.

Beloved bus companies from San Diego to San Antonio, TX

These are the most booked bus companies between San Diego to San Antonio, TX from our users.

FlixBus from San Diego to San Antonio, TX

FlixBus

Here you will find the key facts about the FlixBus bus route San Diego to San Antonio, TX:

Cheapest Price $124
Fastest Bus 35h 45m
Earliest Bus 7:35 AM
Last Bus 7:00 PM
Daily Connections 7 Ø
Found on 6/28/2025

All bus stations and stops in San Diego and San Antonio, TX

In the map below, you can see where to find all bus stations in San Diego and San Antonio, TX.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Diego to San Antonio, TX? Compare all modes of transports from San Diego to San Antonio, TX.

Service and Comfort on the bus from San Diego to San Antonio, TX

Want to know which seat classes are available on the buses from San Diego to San Antonio, TX? Or which bus companies serve the route San Diego to San Antonio, TX? Below you will find answers to your questions.

FAQs about the San Diego to San Antonio, TX bus

How much does a San Diego San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $124 and takes 36h 15m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from San Diego to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $124 and $319. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from San Diego to San Antonio, TX each day?

Every day, the San Diego to San Antonio, TX bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to San Antonio, TX take?

The fastest bus from San Diego to San Antonio, TX is offered by Greyhound US and takes 34h 25m. Bus tickets for this connection cost $213. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from San Diego starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to San Antonio, TX?

The latest bus trip departing from San Diego for San Antonio, TX starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego San Antonio, TX route?

When traveling by bus from San Diego to San Antonio, TX, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and San Antonio, TX?

You can check all the direct connections between San Diego and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to San Antonio, TX on your planned travel date.

Available seat classes which are offered on the bus route San Diego to San Antonio, TX

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to San Antonio, TX

Here’s an overview of the most popular bus routes to San Diego and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!
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