Bus St. Louis, MO to Myrtle Beach, SC: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Myrtle Beach, SC

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Myrtle Beach, SC from various bus operators like FlixBus or Greyhound US for the next days.

today

$124

tomorrow

$116

Wednesday

Thursday

Friday

Saturday

Sunday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	22h 50m	4:00 PM	St. Louis, MO	Gateway Station	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$124	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 1/19/2026 4:00:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/20/2026 3:50:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 22h 50m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 5m	1:45 PM	St. Louis, MO	Gateway Station	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$116	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 1/20/2026 1:45:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/21/2026 3:50:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 25h 5m

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Myrtle Beach, SC is $116 on 1/20/2026. Flexible travelers save on ticket prices.

Facts about the bus from St. Louis, MO to Myrtle Beach, SC

Compare all providers like FlixBus and Greyhound US that travel 1 times every day by bus from St. Louis, MO to Myrtle Beach, SC in one click! Book your bus ticket from St. Louis, MO to Myrtle Beach, SC starting from $116!

Cheapest Bus	$116
Fastest Bus	23h 50m
Earliest Bus	4:00 PM
Latest Bus	1:45 PM
Daily Bus Routes	1 Ø
Distance	717.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from St. Louis, MO to Myrtle Beach, SC

Every day, 1 buses from 2 bus companies leave St. Louis, MO for Myrtle Beach, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$124

Tuesday 01/20

$116

Wednesday 01/21

Thursday 01/22

Friday 01/23

Saturday 01/24

Sunday 01/25

Monday 01/26

$117

Tuesday 01/27

$118

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

How to save money travelling from St. Louis, MO to Myrtle Beach, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Myrtle Beach, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Myrtle Beach, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Myrtle Beach, SC are also emptier.

Beloved bus companies from St. Louis, MO to Myrtle Beach, SC

These are the most booked bus companies between St. Louis, MO to Myrtle Beach, SC from our users.

FlixBus from St. Louis, MO to Myrtle Beach, SC

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Myrtle Beach, SC:

Cheapest Price	$124
Fastest Bus	23h 50m
Earliest Bus	4:00 PM
Last Bus	4:00 PM
Daily Connections	1 Ø
Found on	1/10/2026

All bus stations and stops in St. Louis, MO and Myrtle Beach, SC

In the map below, you can see where to find all bus stations in St. Louis, MO and Myrtle Beach, SC.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Bus Stop

7th Ave N 511

Service and Comfort on the bus from St. Louis, MO to Myrtle Beach, SC

Want to know which seat classes are available on the buses from St. Louis, MO to Myrtle Beach, SC? Or which bus companies serve the route St. Louis, MO to Myrtle Beach, SC? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Myrtle Beach, SC bus

How much does a St. Louis, MO Myrtle Beach, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $116 and takes 26h 5m to reach Myrtle Beach, SC. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Myrtle Beach, SC?

This route is offered by 2 companies with a range of ticket prices between $116 and $124. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Myrtle Beach, SC.

On average, how many connections are available from St. Louis, MO to Myrtle Beach, SC each day?

Every day, the St. Louis, MO to Myrtle Beach, SC bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Myrtle Beach, SC take?

The fastest bus from St. Louis, MO to Myrtle Beach, SC is offered by FlixBus and takes 23h 50m. Bus tickets for this connection cost $124. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Myrtle Beach, SC?

The earliest bus arriving in Myrtle Beach, SC from St. Louis, MO starts at 4:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Myrtle Beach, SC?

The latest bus trip departing from St. Louis, MO for Myrtle Beach, SC starts at 1:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Myrtle Beach, SC route?

When traveling by bus from St. Louis, MO to Myrtle Beach, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Myrtle Beach, SC?

You can check all the direct connections between St. Louis, MO and Myrtle Beach, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the St. Louis, MO to Myrtle Beach, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Myrtle Beach, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Myrtle Beach, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Myrtle Beach, SC on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Myrtle Beach, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between St. Louis, MO and Myrtle Beach, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Myrtle Beach, SC?

Prices and availability for 1 trips between St. Louis, MO and Myrtle Beach, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Myrtle Beach, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Myrtle Beach, SC

Here’s an overview of the most popular bus routes to St. Louis, MO and to Myrtle Beach, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!