Bus Tupelo, MS to Los Angeles: Compare prices and save money

Compare all timetables for the bus from Tupelo, MS to Los Angeles

Here is a selection of the cheapest bus trips from the schedule from Tupelo, MS to Los Angeles from various bus operators like Greyhound US for the next days.

today

tomorrow

$154

Thursday

Friday

$162

Saturday

$138

Sunday

$147

Monday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	43h 45m	9:35 PM	Tupelo, MS	Bus Stop	3:20 PM	Los Angeles	Union Station	Economy	$154	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/25/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/27/2026 3:20:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 43h 45m
Greyhound US	43h 55m	9:35 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$154	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/25/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/27/2026 3:30:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 43h 55m
Greyhound US	49h 15m	11:15 PM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$155	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/25/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 3/27/2026 10:30:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 49h 15m
Greyhound US	42h 55m	5:35 AM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$156	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/25/2026 5:35:00 AM to Union Station, Los Angeles (USA) arriving at 3/26/2026 10:30:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 42h 55m
Greyhound US	66h 15m	11:15 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$156	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/25/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 3/28/2026 3:30:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 66h 15m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	49h 15m	11:15 PM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$162	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/27/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 3/29/2026 10:30:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 49h 15m
Greyhound US	42h 55m	5:35 AM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$163	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/27/2026 5:35:00 AM to Union Station, Los Angeles (USA) arriving at 3/28/2026 10:30:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 42h 55m
Greyhound US	66h 15m	11:15 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$163	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/27/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 3/30/2026 3:30:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 66h 15m
Greyhound US	43h 55m	9:35 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$169	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/27/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/29/2026 3:30:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 43h 55m
Greyhound US	43h 45m	9:35 PM	Tupelo, MS	Bus Stop	3:20 PM	Los Angeles	Union Station	Economy	$169	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/27/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/29/2026 3:20:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 43h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	43h 45m	9:35 PM	Tupelo, MS	Bus Stop	3:20 PM	Los Angeles	Union Station	Economy	$138	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/28/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/30/2026 3:20:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 43h 45m
Greyhound US	43h 55m	9:35 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$138	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/28/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/30/2026 3:30:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 43h 55m
Greyhound US	66h 15m	11:15 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$139	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/28/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 3/31/2026 3:30:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 66h 15m
Greyhound US	42h 55m	5:35 AM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$140	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/28/2026 5:35:00 AM to Union Station, Los Angeles (USA) arriving at 3/29/2026 10:30:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 42h 55m
Greyhound US	49h 15m	11:15 PM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$147	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/28/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 3/30/2026 10:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 49h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	66h 15m	11:15 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$147	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/29/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 4/1/2026 3:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 66h 15m
Greyhound US	43h 45m	9:35 PM	Tupelo, MS	Bus Stop	3:20 PM	Los Angeles	Union Station	Economy	$149	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/29/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/31/2026 3:20:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 43h 45m
Greyhound US	43h 55m	9:35 PM	Tupelo, MS	Bus Stop	3:30 PM	Los Angeles	Union Station	Economy	$149	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/29/2026 9:35:00 PM to Union Station, Los Angeles (USA) arriving at 3/31/2026 3:30:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 43h 55m
Greyhound US	49h 15m	11:15 PM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$149	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/29/2026 11:15:00 PM to Union Station, Los Angeles (USA) arriving at 3/31/2026 10:30:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 49h 15m
Greyhound US	42h 55m	5:35 AM	Tupelo, MS	Bus Stop	10:30 PM	Los Angeles	Union Station	Economy	$154	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 3/29/2026 5:35:00 AM to Union Station, Los Angeles (USA) arriving at 3/30/2026 10:30:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 42h 55m

Best Price Offer: The price for the cheapest bus from Tupelo, MS to Los Angeles is $138 on 3/28/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Tupelo, MS and Los Angeles

See here how frequent the connections between Tupelo, MS and Los Angeles are, during different times and days of the week.

Wednesday is the busiest day, with more than 12 daily buses from Tupelo, MS to Los Angeles. Sunday has instead the fewest connections, with only 5 daily coaches between Tupelo, MS and Los Angeles.

The busiest time of the day is the Evening, with 32 buses from Tupelo, MS to Los Angeles, while Night sees the fewest connections between Tupelo, MS and Los Angeles, with 7 offers.

Facts about the bus from Tupelo, MS to Los Angeles

Compare all providers like Greyhound US that travel 9 times every day by bus from Tupelo, MS to Los Angeles in one click! Book your bus ticket from Tupelo, MS to Los Angeles starting from $138!

Cheapest Bus	$138
Fastest Bus	40h 55m
Earliest Bus	5:35 AM
Latest Bus	11:15 PM
Daily Bus Routes	9 Ø
Distance	1,683.0 miles
Bus Companies	Greyhound US

Cheapest bus connections from Tupelo, MS to Los Angeles

Every day, 9 buses from 1 bus companies leave Tupelo, MS for Los Angeles: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

Monday 03/23

Tuesday 03/24

Wednesday 03/25

$225

Thursday 03/26

Friday 03/27

$162

Saturday 03/28

$138

Sunday 03/29

$147

Monday 03/30

Tuesday 03/31

$174

Wednesday 04/01

$189

Thursday 04/02

$172

Friday 04/03

Saturday 04/04

$221

Sunday 04/05

$157

Monday 04/06

$157

Tuesday 04/07

$220

Wednesday 04/08

$148

Thursday 04/09

$221

Friday 04/10

$222

Saturday 04/11

$162

Sunday 04/12

$144

Monday 04/13

$220

Tuesday 04/14

$155

Wednesday 04/15

$162

Thursday 04/16

$166

Friday 04/17

$221

Saturday 04/18

The cheapest time to travel from Tupelo, MS to Los Angeles

See here on which day and which time of the day you can find the cheapest bus ticket from Tupelo, MS to Los Angeles, for the next 30 days.

With a price starting from $138, Saturday is the cheapest day for a bus from Tupelo, MS to Los Angeles. Friday instead is the most expensive day with prices starting from $162.

Evening is the cheapest day time for bus tickets from Tupelo, MS to Los Angeles, with $138. Evening is the most expensive time of the day with prices starting from $138.

How to save money travelling from Tupelo, MS to Los Angeles

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tupelo, MS to Los Angeles in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tupelo, MS to Los Angeles, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tupelo, MS to Los Angeles are also emptier.

All bus stations and stops in Tupelo, MS and Los Angeles

In the map below, you can see where to find all bus stations in Tupelo, MS and Los Angeles.

Bus Stop

S Eason Blvd 2831

Downtown Bus Station

N Main St 512

Las Casas

Main Street 94

Tufesa

Maple Ave 611

Union Station

Ramirez Street 401-479

Amtrak

Alameda Street 738-788

Service and Comfort on the bus from Tupelo, MS to Los Angeles

Want to know which seat classes are available on the buses from Tupelo, MS to Los Angeles? Or which bus companies serve the route Tupelo, MS to Los Angeles? Below you will find answers to your questions.

FAQs about the Tupelo, MS to Los Angeles bus

How much does a Tupelo, MS Los Angeles bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $138 and takes 41h 45m to reach Los Angeles. Compare offers to save money!

How much could I save by comparing buses from Tupelo, MS to Los Angeles?

This route is offered by 1 companies with a range of ticket prices between $138 and $232. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Los Angeles.

On average, how many connections are available from Tupelo, MS to Los Angeles each day?

Every day, the Tupelo, MS to Los Angeles bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tupelo, MS to Los Angeles take?

The fastest bus from Tupelo, MS to Los Angeles is offered by Greyhound US and takes 40h 55m. Bus tickets for this connection cost $156. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tupelo, MS to Los Angeles?

The earliest bus arriving in Los Angeles from Tupelo, MS starts at 5:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tupelo, MS to Los Angeles?

The latest bus trip departing from Tupelo, MS for Los Angeles starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tupelo, MS Los Angeles route?

When traveling by bus from Tupelo, MS to Los Angeles, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tupelo, MS and Los Angeles?

You can check all the direct connections between Tupelo, MS and Los Angeles by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Tupelo, MS to Los Angeles bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tupelo, MS Los Angeles bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tupelo, MS Los Angeles bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tupelo, MS to Los Angeles on your planned travel date.

How does CheckMyBus find the best bus deals from Tupelo, MS to Los Angeles?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Tupelo, MS and Los Angeles. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tupelo, MS to Los Angeles?

Prices and availability for 9 trips between Tupelo, MS and Los Angeles change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tupelo, MS to Los Angeles

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tupelo, MS and to Los Angeles

Here’s an overview of the most popular bus routes to Tupelo, MS and to Los Angeles. Simply click on the connection of your choice, and you will find all the details about your bus route!