Bus Tyler, TX to San Antonio, TX: Compare prices and save money

Compare all timetables for the bus from Tyler, TX to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Tyler, TX to San Antonio, TX from various bus operators like Greyhound US for the next days.

today

tomorrow

Friday

$113

Saturday

Sunday

Monday

Tuesday

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	8h 20m	3:35 PM	Tyler, TX	Greyhound Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$113	A Bus from Greyhound US goes from Greyhound Bus Station, Tyler, TX (USA) at 12/19/2025 3:35:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/19/2025 11:55:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 8h 20m
Greyhound US	8h 5m	10:50 AM	Tyler, TX	Greyhound Bus Station	6:55 PM	San Antonio, TX	Bus Station	Economy	$118	A Bus from Greyhound US goes from Greyhound Bus Station, Tyler, TX (USA) at 12/19/2025 10:50:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/19/2025 6:55:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 8h 5m
Greyhound US	7h 55m	9:05 PM	Tyler, TX	Greyhound Bus Station	5:00 AM	San Antonio, TX	Bus Station	Economy	$142	A Bus from Greyhound US goes from Greyhound Bus Station, Tyler, TX (USA) at 12/19/2025 9:05:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/20/2025 5:00:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 7h 55m

Did you know that if you travel from Tyler, TX to San Antonio, TX via Austin, you can save more than $25? You can find the corresponding connections below.
- FlixBus
  
  7h 55m
  
  0
  
  9:05 PM
  
  Tyler, TX
  Greyhound Bus Station
  
  3:15 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  0
  
  Economy
  
  $69
  
  A Bus from FlixBus goes from Greyhound Bus Station, Tyler, TX (USA) at 12/18/2025 9:05:00 PM to 5119 Eastside Bus Plaza, Austin (USA) arriving at 12/19/2025 3:15:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 6h 10m
- FlixBus
  
  1h 30m
  
  0
  
  3:30 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:00 AM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $19
  
  A Bus from FlixBus goes from 5119 Eastside Bus Plaza, Austin (USA) at 12/19/2025 3:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/19/2025 5:00:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 1h 30m
Travel time is the same as the direct connection, but you will save $25

Best Price Offer: The price for the cheapest bus from Tyler, TX to San Antonio, TX is $89 on 12/16/2025. Flexible travelers save on ticket prices.

Facts about the bus from Tyler, TX to San Antonio, TX

Compare all providers like Greyhound US that travel 3 times every day by bus from Tyler, TX to San Antonio, TX in one click! Book your bus ticket from Tyler, TX to San Antonio, TX starting from $89!

Cheapest Bus	$89
Fastest Bus	7h 55m
Earliest Bus	10:50 AM
Latest Bus	9:05 PM
Daily Bus Routes	3 Ø
Distance	276.5 miles
Bus Companies	Greyhound US

Cheapest bus connections from Tyler, TX to San Antonio, TX

Every day, 3 buses from 1 bus companies leave Tyler, TX for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$113

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$105

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

How to save money travelling from Tyler, TX to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tyler, TX to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tyler, TX to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tyler, TX to San Antonio, TX are also emptier.

All bus stations and stops in Tyler, TX and San Antonio, TX

In the map below, you can see where to find all bus stations in Tyler, TX and San Antonio, TX.

Greyhound Bus Station

N Bois D Arc St 303

Pilot Travel Center

FM14 A 12881

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

Service and Comfort on the bus from Tyler, TX to San Antonio, TX

Want to know which seat classes are available on the buses from Tyler, TX to San Antonio, TX? Or which bus companies serve the route Tyler, TX to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Tyler, TX to San Antonio, TX bus

How much does a Tyler, TX San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $89 and takes 8h 20m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Tyler, TX to San Antonio, TX?

This route is offered by 1 companies with a range of ticket prices between $89 and $142. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Tyler, TX to San Antonio, TX each day?

Every day, the Tyler, TX to San Antonio, TX bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tyler, TX to San Antonio, TX take?

The fastest bus from Tyler, TX to San Antonio, TX is offered by Greyhound US and takes 7h 55m. Bus tickets for this connection cost $142. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tyler, TX to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Tyler, TX starts at 10:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tyler, TX to San Antonio, TX?

The latest bus trip departing from Tyler, TX for San Antonio, TX starts at 9:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tyler, TX San Antonio, TX route?

When traveling by bus from Tyler, TX to San Antonio, TX, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tyler, TX and San Antonio, TX?

You can check all the direct connections between Tyler, TX and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Tyler, TX to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tyler, TX San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tyler, TX San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tyler, TX to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Tyler, TX to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Tyler, TX and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tyler, TX to San Antonio, TX?

Prices and availability for 3 trips between Tyler, TX and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tyler, TX to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tyler, TX and to San Antonio, TX

Here’s an overview of the most popular bus routes to Tyler, TX and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!