Bus Florence, SC to Birmingham, AL: Compare prices and save money

Compare all timetables for the bus from Florence, SC to Birmingham, AL

Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Birmingham, AL from various bus operators like FlixBus for the next days.

today

tomorrow

Saturday

Sunday

from $100

Monday

Tuesday

Wednesday

Cheapest bus trips Sunday

Prices are for one way and one person

FlixBus

12h 35m

0

5:35 AM

Florence, SC
TA Travel Center

6:10 PM

Birmingham, AL
MAX Central Station

0

Economy

$100

A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 6/15/2025 5:35:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 6/15/2025 6:10:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 12h 35m
FlixBus

14h 55m

0

4:15 PM

Florence, SC
Bus Station

7:10 AM

Birmingham, AL
MAX Central Station

0

Economy

$111

A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/15/2025 4:15:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/16/2025 7:10:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 14h 55m
FlixBus

13h 5m

0

12:55 PM

Florence, SC
Bus Station

2:00 AM

Birmingham, AL
MAX Central Station

0

Economy

$112

A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/15/2025 12:55:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/16/2025 2:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 13h 5m
FlixBus

18h 11m

0

11:59 PM

Florence, SC
TA Travel Center

6:10 PM

Birmingham, AL
MAX Central Station

0

Economy

$159

A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 6/15/2025 11:59:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/16/2025 6:10:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 18h 11m
Did you know that if you travel from Florence, SC to Birmingham, AL via Atlanta, GA, you can save more than $10? You can find the corresponding connections below.
- FlixBus
  
  13h 5m
  
  0
  
  12:55 PM
  
  Florence, SC
  Bus Station
  
  11:35 PM
  
  Atlanta, GA
  Civic Center MARTA Station
  
  0
  
  Economy
  
  $66
  
  A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/15/2025 12:55:00 PM to Civic Center MARTA Station, Atlanta, GA (USA) arriving at 6/15/2025 11:35:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 10h 40m
- Busbud
  
  1h 30m
  
  0
  
  12:30 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  2:00 AM
  
  Birmingham, AL
  MAX Central Station
  
  0
  
  Economy
  
  $24
  
  A Bus from Busbud goes from Garnett Transit Station, Atlanta, GA (USA) at 6/16/2025 12:30:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 6/16/2025 2:00:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 30m
Travel time is 0h 30m longer, but you will save $10

Facts about the bus from Florence, SC to Birmingham, AL

Compare all providers like FlixBus that travel 4 times every day by bus from Florence, SC to Birmingham, AL in one click! Book your bus ticket from Florence, SC to Birmingham, AL starting from $100!

Cheapest Bus	$100
Fastest Bus	12h 35m
Earliest Bus	5:35 AM
Latest Bus	11:59 PM
Daily Bus Routes	4 Ø
Distance	407.1 miles
Bus Companies	FlixBus

Cheapest bus connections from Florence, SC to Birmingham, AL

Every day, 4 buses from 1 bus companies leave Florence, SC for Birmingham, AL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/12/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/08

Monday 06/09

Tuesday 06/10

Wednesday 06/11

Thursday 06/12

Friday 06/13

Saturday 06/14

Sunday 06/15

$100

Monday 06/16

Tuesday 06/17

Wednesday 06/18

Thursday 06/19

Friday 06/20

Saturday 06/21

Sunday 06/22

Monday 06/23

Tuesday 06/24

Wednesday 06/25

Thursday 06/26

Friday 06/27

Saturday 06/28

Sunday 06/29

Monday 06/30

Tuesday 07/01

Wednesday 07/02

Thursday 07/03

Friday 07/04

Saturday 07/05

How to save money travelling from Florence, SC to Birmingham, AL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence, SC to Birmingham, AL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Birmingham, AL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Birmingham, AL are also emptier.

All bus stations and stops in Florence, SC and Birmingham, AL

In the map below, you can see where to find all bus stations in Florence, SC and Birmingham, AL.

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

MAX Central Station

Morris Ave 1735

Homewood

Green Springs Hwy 22

Cahaba

7th Ave S #205 2717

Service and Comfort on the bus from Florence, SC to Birmingham, AL

Want to know which seat classes are available on the buses from Florence, SC to Birmingham, AL? Or which bus companies serve the route Florence, SC to Birmingham, AL? Below you will find answers to your questions.

FAQs about the Florence, SC to Birmingham, AL bus

How much does a Florence, SC Birmingham, AL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $100 and takes 12h 35m to reach Birmingham, AL. Compare offers to save money!

How much could I save by comparing buses from Florence, SC to Birmingham, AL?

This route is offered by 1 companies with a range of ticket prices between $100 and $159. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Birmingham, AL.

On average, how many connections are available from Florence, SC to Birmingham, AL each day?

Every day, the Florence, SC to Birmingham, AL bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence, SC to Birmingham, AL take?

The fastest bus from Florence, SC to Birmingham, AL is offered by FlixBus and takes 12h 35m. Bus tickets for this connection cost $100. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence, SC to Birmingham, AL?

The earliest bus arriving in Birmingham, AL from Florence, SC starts at 5:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence, SC to Birmingham, AL?

The latest bus trip departing from Florence, SC for Birmingham, AL starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence, SC Birmingham, AL route?

When traveling by bus from Florence, SC to Birmingham, AL, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence, SC and Birmingham, AL?

You can check all the direct connections between Florence, SC and Birmingham, AL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Florence, SC to Birmingham, AL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Birmingham, AL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence, SC Birmingham, AL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Birmingham, AL on your planned travel date.

Available seat classes which are offered on the bus route Florence, SC to Birmingham, AL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Florence, SC and to Birmingham, AL

Here’s an overview of the most popular bus routes to Florence, SC and to Birmingham, AL. Simply click on the connection of your choice, and you will find all the details about your bus route!