Compare all timetables for the bus from Florence to Messina
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 20m | 6:00 PM | Florence | Villa Costanza Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $39 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 4/29/2026 6:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 4/30/2026 6:20:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 12h 20m
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| FlixBus | 13h 10m | 10:00 PM | Florence | Villa Costanza Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $43 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 4/29/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 4/30/2026 11:10:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 10m
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| Itabus | 14h 20m | 3:25 PM | Florence | Villa Costanza Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $58 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 4/29/2026 3:25:00 PM to Central Station, Messina (Italy) arriving at 4/30/2026 5:45:00 AM. 50 Premium Economy ticket for $58 per person are available. Travel duration is 14h 20m
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| Trenitalia | 14h 55m | 12:40 AM | Florence | Santa Maria Novella Central Station | 3:35 PM | Messina | Central Station | Economy | $100 |
A Bus from Trenitalia goes from Santa Maria Novella Central Station, Florence (Italy) at 4/29/2026 12:40:00 AM to Central Station, Messina (Italy) arriving at 4/29/2026 3:35:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 14h 55m
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Save more than 67%0h 54m0 mi4:51 AMVilla San GiovanniStation5:45 AMMessinaCentral Station447 miFlorencePremium EconomyA Bus from goes from Station, Villa San Giovanni (Italy) at 4/29/2026 4:51:00 AM to Central Station, Messina (Italy) arriving at 4/29/2026 5:45:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 0h 54m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 20m | 6:00 PM | Florence | Villa Costanza Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $49 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 4/30/2026 6:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/1/2026 6:20:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 12h 20m
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| Itabus | 19h 45m | 11:05 AM | Florence | Villa Costanza Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $61 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 4/30/2026 11:05:00 AM to Central Station, Messina (Italy) arriving at 5/1/2026 6:50:00 AM. 50 Premium Economy ticket for $61 per person are available. Travel duration is 19h 45m
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| FlixBus | 13h 10m | 10:00 PM | Florence | Villa Costanza Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $68 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 4/30/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/1/2026 11:10:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 13h 10m
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| Itabus | 18h 30m | 12:20 PM | Florence | Villa Costanza Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $78 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 4/30/2026 12:20:00 PM to Central Station, Messina (Italy) arriving at 5/1/2026 6:50:00 AM. 50 Premium Economy ticket for $78 per person are available. Travel duration is 18h 30m
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| Trenitalia | 14h 55m | 12:40 AM | Florence | Santa Maria Novella Central Station | 3:35 PM | Messina | Central Station | Economy | $123 |
A Bus from Trenitalia goes from Santa Maria Novella Central Station, Florence (Italy) at 4/30/2026 12:40:00 AM to Central Station, Messina (Italy) arriving at 4/30/2026 3:35:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 14h 55m
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Save more than 47%0h 54m0 mi4:51 AMVilla San GiovanniStation5:45 AMMessinaCentral Station447 miFlorencePremium EconomyA Bus from goes from Station, Villa San Giovanni (Italy) at 4/30/2026 4:51:00 AM to Central Station, Messina (Italy) arriving at 4/30/2026 5:45:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 0h 54m
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BlaBlaCar Bus13h 45m04:45 PMFlorencePiazza della Stazione Bus Station11:10 PMNaplesMetropark Centrale0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 5/1/2026 4:45:00 PM to Metropark Centrale, Naples (Italy) arriving at 5/1/2026 11:10:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 6h 25m
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FlixBus6h 45m011:45 PMNaplesMetropark Centrale6:30 AMMessinaPiazza della Repubblica0EconomyA Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 5/1/2026 11:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/2/2026 6:30:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 45m
Waiting Time 0h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 20m | 3:25 PM | Florence | Villa Costanza Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $58 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/1/2026 3:25:00 PM to Central Station, Messina (Italy) arriving at 5/2/2026 5:45:00 AM. 50 Premium Economy ticket for $58 per person are available. Travel duration is 14h 20m
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| FlixBus | 16h 0m | 3:50 AM | Florence | Villa Costanza Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $65 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/1/2026 3:50:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 5/1/2026 7:50:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 0m
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| FlixBus | 12h 20m | 6:00 PM | Florence | Villa Costanza Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $68 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/1/2026 6:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/2/2026 6:20:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 12h 20m
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| Itabus | 19h 45m | 11:05 AM | Florence | Villa Costanza Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $70 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/1/2026 11:05:00 AM to Central Station, Messina (Italy) arriving at 5/2/2026 6:50:00 AM. 50 Premium Economy ticket for $70 per person are available. Travel duration is 19h 45m
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| FlixBus | 13h 10m | 10:00 PM | Florence | Villa Costanza Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $76 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/1/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/2/2026 11:10:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 13h 10m
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0h 54m0 mi4:51 AMVilla San GiovanniStation5:45 AMMessinaCentral Station447 miFlorencePremium EconomyA Bus from goes from Station, Villa San Giovanni (Italy) at 5/1/2026 4:51:00 AM to Central Station, Messina (Italy) arriving at 5/1/2026 5:45:00 AM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 0h 54m
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Itabus13h 35m04:55 PMFlorenceVilla Costanza Bus Station8:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/2/2026 4:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 8:45:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 3h 50m
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FlixBus9h 30m09:00 PMRomeTiburtina Bus Station6:30 AMMessinaPiazza della Repubblica0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/2/2026 9:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/3/2026 6:30:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 9h 30m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 20m | 6:00 PM | Florence | Villa Costanza Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $43 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/2/2026 6:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/3/2026 6:20:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 12h 20m
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| FlixBus | 13h 10m | 10:00 PM | Florence | Villa Costanza Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $44 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/2/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/3/2026 11:10:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 13h 10m
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| FlixBus | 15h 50m | 4:00 AM | Florence | Piazzale Montelungo Bus Stop | 7:50 PM | Messina | Piazza della Repubblica | Economy | $45 |
A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 5/2/2026 4:00:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 5/2/2026 7:50:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 15h 50m
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| Itabus | 19h 45m | 11:05 AM | Florence | Villa Costanza Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $53 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/2/2026 11:05:00 AM to Central Station, Messina (Italy) arriving at 5/3/2026 6:50:00 AM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 19h 45m
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| Itabus | 14h 20m | 3:25 PM | Florence | Villa Costanza Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Premium Economy | $55 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/2/2026 3:25:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/3/2026 5:45:00 AM. 50 Premium Economy ticket for $55 per person are available. Travel duration is 14h 20m
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Itabus13h 35m04:55 PMFlorenceVilla Costanza Bus Station8:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/2/2026 4:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 8:45:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 3h 50m
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FlixBus9h 30m09:00 PMRomeTiburtina Bus Station6:30 AMMessinaPiazza della Repubblica0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 5/2/2026 9:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/3/2026 6:30:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 9h 30m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 10m | 10:00 PM | Florence | Villa Costanza Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $63 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/3/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/4/2026 11:10:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 13h 10m
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| Itabus | 19h 45m | 11:05 AM | Florence | Villa Costanza Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $63 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/3/2026 11:05:00 AM to Central Station, Messina (Italy) arriving at 5/4/2026 6:50:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 19h 45m
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| Itabus | 18h 30m | 12:20 PM | Florence | Villa Costanza Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $63 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/3/2026 12:20:00 PM to Central Station, Messina (Italy) arriving at 5/4/2026 6:50:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 18h 30m
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| Itabus | 14h 20m | 3:25 PM | Florence | Villa Costanza Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $70 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/3/2026 3:25:00 PM to Central Station, Messina (Italy) arriving at 5/4/2026 5:45:00 AM. 50 Premium Economy ticket for $70 per person are available. Travel duration is 14h 20m
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| FlixBus | 12h 20m | 6:00 PM | Florence | Villa Costanza Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $97 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/3/2026 6:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/4/2026 6:20:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 12h 20m
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Save more than 79%0h 59m0 mi5:51 AMVilla San GiovanniStation6:50 AMMessinaCentral Station447 miFlorencePremium EconomyA Bus from goes from Station, Villa San Giovanni (Italy) at 5/3/2026 5:51:00 AM to Central Station, Messina (Italy) arriving at 5/3/2026 6:50:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 0h 59m
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FlixBus16h 0m03:50 AMFlorenceVilla Costanza Bus Station9:50 AMNaplesMetropark Centrale0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/5/2026 3:50:00 AM to Metropark Centrale, Naples (Italy) arriving at 5/5/2026 9:50:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 6h 0m
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FlixBus7h 55m011:55 AMNaplesMetropark Centrale7:50 PMMessinaPiazza della Repubblica0EconomyA Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 5/5/2026 11:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 5/5/2026 7:50:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 7h 55m
Waiting Time 2h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 10m | 10:00 PM | Florence | Villa Costanza Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/4/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/5/2026 11:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 13h 10m
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| FlixBus | 12h 20m | 6:00 PM | Florence | Villa Costanza Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $39 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/4/2026 6:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/5/2026 6:20:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 12h 20m
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| FlixBus | 15h 25m | 4:25 AM | Florence | Villa Costanza Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $47 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/4/2026 4:25:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 5/4/2026 7:50:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 25m
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| Itabus | 14h 20m | 3:25 PM | Florence | Villa Costanza Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Premium Economy | $61 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 5/4/2026 3:25:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/5/2026 5:45:00 AM. 50 Premium Economy ticket for $61 per person are available. Travel duration is 14h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 20m | 6:00 PM | Florence | Villa Costanza Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $27 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/5/2026 6:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/6/2026 6:20:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 12h 20m
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| FlixBus | 13h 10m | 10:00 PM | Florence | Villa Costanza Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $27 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/5/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 5/6/2026 11:10:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 13h 10m
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| FlixBus | 15h 50m | 4:00 AM | Florence | Piazzale Montelungo Bus Stop | 7:50 PM | Messina | Piazza della Repubblica | Economy | $38 |
A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 5/5/2026 4:00:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 5/5/2026 7:50:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 15h 50m
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| FlixBus | 17h 15m | 12:40 AM | Florence | Villa Costanza Bus Station | 5:55 PM | Messina | Piazza della Repubblica | Economy | $43 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 5/5/2026 12:40:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 5/5/2026 5:55:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 17h 15m
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| FlixBus | 16h 50m | 1:05 AM | Florence | Piazzale Montelungo Bus Stop | 5:55 PM | Messina | Piazza della Repubblica | Economy | $43 |
A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 5/5/2026 1:05:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 5/5/2026 5:55:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 16h 50m
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Best Price Offer: The price for the cheapest bus from Florence to Messina is $25 on 5/11/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Florence and Messina
Facts about the bus from Florence to Messina
Compare all providers like Itabus, FlixBus and Trenitalia that travel 12 times every day by bus from Florence to Messina in one click! Book your bus ticket from Florence to Messina starting from $25!
| Cheapest Bus | $25 |
| Fastest Bus | 12h 20m |
| Earliest Bus | 12:40 AM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 12 Ø |
| Distance | 446.0 miles |
| Bus Companies | Itabus, FlixBus and Trenitalia |
Cheapest bus connections from Florence to Messina
Every day, 12 buses from 3 bus companies leave Florence for Messina: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/29/2026 and for the following days.
The cheapest time to travel from Florence to Messina
How to save money travelling from Florence to Messina
Book the ticket from Florence to Messina in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence to Messina, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence to Messina are also emptier.All bus stations and stops in Florence and Messina
In the map below, you can see where to find all bus stations in Florence and Messina.
Compare the bus with other modes of transport
Service and Comfort on the bus from Florence to Messina
FAQs about the Florence to Messina bus
How much does a Florence Messina bus trip cost?
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On average, how many connections are available from Florence to Messina each day?
How long does a bus journey from Florence to Messina take?
What time is the first bus from Florence to Messina?
What time is the last bus from Florence to Messina?
Which bus companies operate the Florence Messina route?
Is there a direct bus between Florence and Messina?
What can I take with me on the Florence to Messina bus route?
What equipment is available for the Florence Messina bus route?
How does CheckMyBus find the best bus deals from Florence to Messina?
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Available seat classes which are offered on the bus route Florence to Messina
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Florence and to Messina
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