Bus Hesperia, CA to San Diego - Compare all Companies

Compare all timetables for the bus from Hesperia, CA to San Diego

Here is a selection of the cheapest bus trips from the schedule from Hesperia, CA to San Diego from various bus operators like Las Vegas Shuttles for the next days.

today

$78

tomorrow

$79

Monday

$79

Tuesday

$77

Wednesday

Thursday

$79

Friday

$79

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Las Vegas Shuttles	3h 12m	1:26 AM	Hesperia, CA	Key Pointe Ave NB	4:38 AM	San Diego	San Ysidro Transit Center	Economy	$78	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/20/2026 1:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/20/2026 4:38:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	9:26 AM	Hesperia, CA	Key Pointe Ave NB	12:38 PM	San Diego	San Ysidro Transit Center	Economy	$78	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/20/2026 9:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/20/2026 12:38:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	12:26 PM	Hesperia, CA	Key Pointe Ave NB	3:38 PM	San Diego	San Ysidro Transit Center	Economy	$78	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/20/2026 12:26:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/20/2026 3:38:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 3h 12m

Did you know that if you travel from Hesperia, CA to San Diego via Victorville, CA, you can save more than $30? You will find the corresponding connections below.
- Save more than 38%
  
  7h 10m
  
  Hesperia, CA
  
  8 mi
  
  10:40 AM
  
  Victorville, CA
  Bus Stop
  
  5:50 PM
  
  San Diego
  Old Town Transit Center
  
  0 mi
  
  Economy
  
  $48
  
  A Bus from goes from Bus Stop, Victorville, CA (USA) at 6/20/2026 10:40:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/20/2026 5:50:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 7h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Las Vegas Shuttles	3h 12m	1:26 AM	Hesperia, CA	Key Pointe Ave NB	4:38 AM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/21/2026 1:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/21/2026 4:38:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	9:26 AM	Hesperia, CA	Key Pointe Ave NB	12:38 PM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/21/2026 9:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/21/2026 12:38:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	12:26 PM	Hesperia, CA	Key Pointe Ave NB	3:38 PM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/21/2026 12:26:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/21/2026 3:38:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m

Did you know that if you travel from Hesperia, CA to San Diego via Victorville, CA, you can save more than $31? You will find the corresponding connections below.
- Save more than 39%
  
  7h 10m
  
  Hesperia, CA
  
  8 mi
  
  10:40 AM
  
  Victorville, CA
  Bus Stop
  
  5:50 PM
  
  San Diego
  Old Town Transit Center
  
  0 mi
  
  Economy
  
  $48
  
  A Bus from goes from Bus Stop, Victorville, CA (USA) at 6/21/2026 10:40:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/21/2026 5:50:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 7h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Las Vegas Shuttles	3h 12m	1:26 AM	Hesperia, CA	Key Pointe Ave NB	4:38 AM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/22/2026 1:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/22/2026 4:38:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	9:26 AM	Hesperia, CA	Key Pointe Ave NB	12:38 PM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/22/2026 9:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/22/2026 12:38:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	12:26 PM	Hesperia, CA	Key Pointe Ave NB	3:38 PM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/22/2026 12:26:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/22/2026 3:38:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m

Did you know that if you travel from Hesperia, CA to San Diego via Victorville, CA, you can save more than $33? You will find the corresponding connections below.
- Save more than 42%
  
  7h 40m
  
  Hesperia, CA
  
  8 mi
  
  10:40 AM
  
  Victorville, CA
  Bus Stop
  
  6:20 PM
  
  San Diego
  San Ysidro Transit Center
  
  0 mi
  
  Economy
  
  $46
  
  A Bus from goes from Bus Stop, Victorville, CA (USA) at 6/22/2026 10:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/22/2026 6:20:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 7h 40m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Las Vegas Shuttles	2h 51m	1:26 AM	Hesperia, CA	Key Pointe Ave NB	4:17 AM	San Diego	University Av & 39th St		Economy	$77	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/23/2026 1:26:00 AM to University Av & 39th St, San Diego (USA) arriving at 6/23/2026 4:17:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 2h 51m
	Las Vegas Shuttles	2h 51m	12:26 PM	Hesperia, CA	Key Pointe Ave NB	3:17 PM	San Diego	University Av & 39th St		Economy	$77	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/23/2026 12:26:00 PM to University Av & 39th St, San Diego (USA) arriving at 6/23/2026 3:17:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 2h 51m

Did you know that if you travel from Hesperia, CA to San Diego via Victorville, CA, you can save more than $12? You will find the corresponding connections below.
- Tufesa International
  
  Save more than 16%
  
  4h 0m
  
  Hesperia, CA
  
  8 mi
  
  1:00 AM
  
  Victorville, CA
  Bus Stop
  
  5:00 AM
  
  San Diego
  San Ysidro Transit Center
  
  0 mi
  
  Economy
  
  $65
  
  A Bus from Tufesa International goes from Bus Stop, Victorville, CA (USA) at 6/23/2026 1:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/23/2026 5:00:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 4h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Las Vegas Shuttles	2h 51m	1:26 AM	Hesperia, CA	Key Pointe Ave NB	4:17 AM	San Diego	University Av & 39th St	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/25/2026 1:26:00 AM to University Av & 39th St, San Diego (USA) arriving at 6/25/2026 4:17:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 2h 51m
Las Vegas Shuttles	2h 51m	9:26 AM	Hesperia, CA	Key Pointe Ave NB	12:17 PM	San Diego	University Av & 39th St	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/25/2026 9:26:00 AM to University Av & 39th St, San Diego (USA) arriving at 6/25/2026 12:17:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 2h 51m
Las Vegas Shuttles	2h 51m	12:26 PM	Hesperia, CA	Key Pointe Ave NB	3:17 PM	San Diego	University Av & 39th St	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/25/2026 12:26:00 PM to University Av & 39th St, San Diego (USA) arriving at 6/25/2026 3:17:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 2h 51m

Did you know that if you travel from Hesperia, CA to San Diego via Victorville, CA, you can save more than $14? You will find the corresponding connections below.
- Tufesa International
  
  Save more than 18%
  
  4h 0m
  
  Hesperia, CA
  
  8 mi
  
  2:45 AM
  
  Victorville, CA
  Bus Stop
  
  6:45 AM
  
  San Diego
  San Ysidro Transit Center
  
  0 mi
  
  Economy
  
  $65
  
  A Bus from Tufesa International goes from Bus Stop, Victorville, CA (USA) at 6/25/2026 2:45:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/25/2026 6:45:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 4h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Las Vegas Shuttles	3h 12m	1:26 AM	Hesperia, CA	Key Pointe Ave NB	4:38 AM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/26/2026 1:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/26/2026 4:38:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	9:26 AM	Hesperia, CA	Key Pointe Ave NB	12:38 PM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/26/2026 9:26:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/26/2026 12:38:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	3h 12m	12:26 PM	Hesperia, CA	Key Pointe Ave NB	3:38 PM	San Diego	San Ysidro Transit Center	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/26/2026 12:26:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/26/2026 3:38:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 3h 12m
Las Vegas Shuttles	2h 51m	1:26 AM	Hesperia, CA	Key Pointe Ave NB	4:17 AM	San Diego	University Av & 39th St	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/26/2026 1:26:00 AM to University Av & 39th St, San Diego (USA) arriving at 6/26/2026 4:17:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 2h 51m
Las Vegas Shuttles	2h 51m	9:26 AM	Hesperia, CA	Key Pointe Ave NB	12:17 PM	San Diego	University Av & 39th St	Economy	$79	A Bus from Las Vegas Shuttles goes from Key Pointe Ave NB, Hesperia, CA (USA) at 6/26/2026 9:26:00 AM to University Av & 39th St, San Diego (USA) arriving at 6/26/2026 12:17:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 2h 51m

Did you know that if you travel from Hesperia, CA to San Diego via Victorville, CA, you can save more than $40? You will find the corresponding connections below.
- Save more than 51%
  
  7h 10m
  
  Hesperia, CA
  
  8 mi
  
  10:40 AM
  
  Victorville, CA
  Bus Stop
  
  5:50 PM
  
  San Diego
  Old Town Transit Center
  
  0 mi
  
  Economy
  
  $39
  
  A Bus from goes from Bus Stop, Victorville, CA (USA) at 6/26/2026 10:40:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/26/2026 5:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 7h 10m

Best Price Offer: The price for the cheapest bus from Hesperia, CA to San Diego is $69 on 6/17/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Hesperia, CA and San Diego

See here how frequent the connections between Hesperia, CA and San Diego are, during different times and days of the week.

Friday is the busiest day, with more than 6 daily buses from Hesperia, CA to San Diego. Tuesday has instead the fewest connections, with only 2 daily coaches between Hesperia, CA and San Diego.

The busiest time of the day is the Afternoon, with 7 buses from Hesperia, CA to San Diego, while Morning sees the fewest connections between Hesperia, CA and San Diego, with 6 offers.

Facts about the bus from Hesperia, CA to San Diego

Compare all providers like Las Vegas Shuttles that travel 3 times every day by bus from Hesperia, CA to San Diego in one click! Book your bus ticket from Hesperia, CA to San Diego starting from $69!

Cheapest Bus	$69
Fastest Bus	2h 51m
Earliest Bus	1:26 AM
Latest Bus	12:26 PM
Daily Bus Routes	3 Ø
Distance	118.1 miles
Bus Companies	Las Vegas Shuttles

Cheapest bus connections from Hesperia, CA to San Diego

Every day, 3 buses from 1 bus companies leave Hesperia, CA for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/14

Monday 06/15

Tuesday 06/16

Wednesday 06/17

Thursday 06/18

Friday 06/19

Saturday 06/20

$78

Sunday 06/21

$79

Monday 06/22

$69

Tuesday 06/23

$69

Wednesday 06/24

$77

Thursday 06/25

$77

Friday 06/26

$79

Saturday 06/27

$79

Sunday 06/28

$77

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

$78

Saturday 07/11

The cheapest time to travel from Hesperia, CA to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Hesperia, CA to San Diego, for the next 30 days.

With a price starting from $69, Sunday is the cheapest day for a bus from Hesperia, CA to San Diego. Friday instead is the most expensive day with prices starting from $78.

Night is the cheapest day time for bus tickets from Hesperia, CA to San Diego, with $69. Morning is the most expensive time of the day with prices starting from $78.

How to save money travelling from Hesperia, CA to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Hesperia, CA to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Hesperia, CA to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Hesperia, CA to San Diego are also emptier.

All bus stations and stops in Hesperia, CA and San Diego

In the map below, you can see where to find all bus stations in Hesperia, CA and San Diego.

Key Pointe Ave NB

Bear Valley Rd EB

Bus Stop

Mountain Vista Ave FS

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Hesperia, CA to San Diego

Want to know which seat classes are available on the buses from Hesperia, CA to San Diego? Or which bus companies serve the route Hesperia, CA to San Diego? Below you will find answers to your questions.

FAQs about the Hesperia, CA to San Diego bus

How much does a Hesperia, CA San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $69 and takes 2h 51m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Hesperia, CA to San Diego?

This route is offered by 1 companies with a range of ticket prices between $69 and $79. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Hesperia, CA to San Diego each day?

Every day, the Hesperia, CA to San Diego bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Hesperia, CA to San Diego take?

The fastest bus from Hesperia, CA to San Diego is offered by Las Vegas Shuttles and takes 2h 51m. Bus tickets for this connection cost $77. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Hesperia, CA to San Diego?

The earliest bus arriving in San Diego from Hesperia, CA starts at 1:26 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Hesperia, CA to San Diego?

The latest bus trip departing from Hesperia, CA for San Diego starts at 12:26 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Hesperia, CA San Diego route?

When traveling by bus from Hesperia, CA to San Diego, passengers can travel with Las Vegas Shuttles. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Hesperia, CA and San Diego?

You can check all the direct connections between Hesperia, CA and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Las Vegas Shuttles.

What can I take with me on the Hesperia, CA to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Hesperia, CA San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Hesperia, CA San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Hesperia, CA to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Hesperia, CA to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Hesperia, CA and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Hesperia, CA to San Diego?

Prices and availability for 3 trips between Hesperia, CA and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Hesperia, CA to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Hesperia, CA and to San Diego

Here’s an overview of the most popular bus routes to Hesperia, CA and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!