Bus Karlsruhe to Brno: Compare prices and save money

Compare all timetables for the bus from Karlsruhe to Brno

Here is a selection of the cheapest bus trips from the schedule from Karlsruhe to Brno from various bus operators like FlixBus, Openline or Like Bus for the next days.

today

$42

tomorrow

Wednesday

Thursday

Friday

Saturday

$48

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 50m	12:30 PM	Karlsruhe	Central Station	1:20 AM	Brno	Hotel Grand	Economy	$42	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 1/19/2026 12:30:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 1/20/2026 1:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 12h 50m
FlixBus	15h 50m	2:00 PM	Karlsruhe	Central Station	5:50 AM	Brno	Hotel Grand	Economy	$43	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 1/19/2026 2:00:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 1/20/2026 5:50:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 15h 50m
FlixBus	13h 25m	6:35 AM	Karlsruhe	Central Station	8:00 PM	Brno	Hotel Grand	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 1/19/2026 6:35:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 1/19/2026 8:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 13h 25m
Openline	13h 35m	7:50 AM	Karlsruhe	Central Station	9:25 PM	Brno	Hotel Grand	Economy	$58	A Bus from Openline goes from Central Station, Karlsruhe (Germany) at 1/19/2026 7:50:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 1/19/2026 9:25:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 13h 35m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 45m	2:15 AM	Karlsruhe	Central Station	3:00 PM	Brno	Hotel Grand	Economy	$48	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 1/24/2026 2:15:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 1/24/2026 3:00:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 12h 45m
FlixBus	13h 25m	6:35 AM	Karlsruhe	Central Station	8:00 PM	Brno	Hotel Grand	Economy	$48	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 1/24/2026 6:35:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 1/24/2026 8:00:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 13h 25m
FlixBus	13h 40m	10:15 AM	Karlsruhe	Central Station	11:55 PM	Brno	Hotel Grand	Economy	$48	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 1/24/2026 10:15:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 1/24/2026 11:55:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 13h 40m
Openline	13h 35m	7:50 AM	Karlsruhe	Central Station	9:25 PM	Brno	Hotel Grand	Economy	$58	A Bus from Openline goes from Central Station, Karlsruhe (Germany) at 1/24/2026 7:50:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 1/24/2026 9:25:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 13h 35m

Best Price Offer: The price for the cheapest bus from Karlsruhe to Brno is $42 on 1/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Karlsruhe and Brno

See here how frequent the connections between Karlsruhe and Brno are, during different times and days of the week.

Saturday is the busiest day, with more than 11 daily buses from Karlsruhe to Brno. Monday has instead the fewest connections, with only 9 daily coaches between Karlsruhe and Brno.

The busiest time of the day is the Morning, with 10 buses from Karlsruhe to Brno, while Night sees the fewest connections between Karlsruhe and Brno, with 1 offers.

Facts about the bus from Karlsruhe to Brno

Compare all providers like FlixBus, Openline and Like Bus that travel 10 times every day by bus from Karlsruhe to Brno in one click! Book your bus ticket from Karlsruhe to Brno starting from $42!

Cheapest Bus	$42
Fastest Bus	12h 25m
Earliest Bus	6:35 AM
Latest Bus	11:30 PM
Daily Bus Routes	10 Ø
Distance	371.3 miles
Bus Companies	FlixBus, Openline and Like Bus

Cheapest bus connections from Karlsruhe to Brno

Every day, 10 buses from 3 bus companies leave Karlsruhe for Brno: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$58

Tuesday 01/20

Wednesday 01/21

Thursday 01/22

Friday 01/23

Saturday 01/24

$48

Sunday 01/25

Monday 01/26

$58

Tuesday 01/27

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Karlsruhe to Brno

See here on which day and which time of the day you can find the cheapest bus ticket from Karlsruhe to Brno, for the next 30 days.

With a price starting from $42, Monday is the cheapest day for a bus from Karlsruhe to Brno. Saturday instead is the most expensive day with prices starting from $48.

Afternoon is the cheapest day time for bus tickets from Karlsruhe to Brno, with $42. Night is the most expensive time of the day with prices starting from $48.

How to save money travelling from Karlsruhe to Brno

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlsruhe to Brno in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Brno, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Brno are also emptier.

All bus stations and stops in Karlsruhe and Brno

In the map below, you can see where to find all bus stations in Karlsruhe and Brno.

Central Bus Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Bannwaldallee Station

Kühler Krug Train Station

Stadtwerke Bus Stop

Hotel Grand

Benešova

ÚAN Zvonařka

Zvonařka 470/2b

Ikea

Dolní Nádraží

Service and Comfort on the bus from Karlsruhe to Brno

Want to know which seat classes are available on the buses from Karlsruhe to Brno? Or which bus companies serve the route Karlsruhe to Brno? Below you will find answers to your questions.

FAQs about the Karlsruhe to Brno bus

How much does a Karlsruhe Brno bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 12h 50m to reach Brno. Compare offers to save money!

How much could I save by comparing buses from Karlsruhe to Brno?

This route is offered by 3 companies with a range of ticket prices between $42 and $58. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brno.

On average, how many connections are available from Karlsruhe to Brno each day?

Every day, the Karlsruhe to Brno bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlsruhe to Brno take?

The fastest bus from Karlsruhe to Brno is offered by FlixBus and takes 12h 25m. Bus tickets for this connection cost $48. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlsruhe to Brno?

The earliest bus arriving in Brno from Karlsruhe starts at 6:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlsruhe to Brno?

The latest bus trip departing from Karlsruhe for Brno starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlsruhe Brno route?

When traveling by bus from Karlsruhe to Brno, passengers can travel with FlixBus, Openline and Like Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlsruhe and Brno?

You can check all the direct connections between Karlsruhe and Brno by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Openline and Like Bus.

What can I take with me on the Karlsruhe to Brno bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlsruhe Brno bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlsruhe Brno bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlsruhe to Brno on your planned travel date.

How does CheckMyBus find the best bus deals from Karlsruhe to Brno?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Karlsruhe and Brno. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Karlsruhe to Brno?

Prices and availability for 10 trips between Karlsruhe and Brno change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Karlsruhe to Brno

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlsruhe and to Brno

Here’s an overview of the most popular bus routes to Karlsruhe and to Brno. Simply click on the connection of your choice, and you will find all the details about your bus route!