Bus from Karlsruhe to Brno from $43

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Compare all timetables for the bus from Karlsruhe to Brno

Here is a selection of the cheapest bus trips from the schedule from Karlsruhe to Brno from various bus operators like FlixBus, Openline or Like Bus for the next days.

today
$58
tomorrow
Wednesday
Thursday
Friday
Saturday
$58
Sunday
$49

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Openline 13h 35m 7:50 AM Karlsruhe Central Station 9:25 PM Brno Hotel Grand  Economy $58
  • Did you know that if you travel from Karlsruhe to Brno via Stuttgart Airport, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      14h 30m
      0
      6:25 PM
      Karlsruhe
      Central Station
      7:20 PM
      Stuttgart Airport
      Stuttgart Airport
      0
      FlixBus
      Economy
      $7
      • Waiting Time 1h 15m
    • FlixBus
      12h 20m
      0
      8:35 PM
      Stuttgart Airport
      Stuttgart Airport
      8:55 AM
      Brno
      Hotel Grand
      0
      FlixBus
      Economy
      $40
    Travel time is 0h 55m longer, but you will save $11

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Openline 13h 35m 7:50 AM Karlsruhe Central Station 9:25 PM Brno Hotel Grand  Economy $58
  • Did you know that if you travel from Karlsruhe to Brno via Pilsen, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      19h 30m
      0
      6:25 AM
      Karlsruhe
      Central Station
      1:50 PM
      Pilsen
      Central bus station CAN
      0
      FlixBus
      Economy
      $31
      • Waiting Time 6h 20m
    • FlixBus
      5h 45m
      0
      8:10 PM
      Pilsen
      Central bus station CAN
      1:55 AM
      Brno
      Hotel Grand
      0
      FlixBus
      Economy
      $11
    Travel time is 5h 55m longer, but you will save $16

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 12h 45m 2:15 AM Karlsruhe Central Station 3:00 PM Brno Hotel Grand  Economy $49
FlixBus 13h 25m 6:35 AM Karlsruhe Central Station 8:00 PM Brno Hotel Grand  Economy $49
FlixBus 12h 50m 12:30 PM Karlsruhe Central Station 1:20 AM Brno Hotel Grand  Economy $49
FlixBus 12h 35m 1:20 PM Karlsruhe Central Station 1:55 AM Brno Hotel Grand  Economy $49
FlixBus 13h 30m 4:20 PM Karlsruhe Central Station 5:50 AM Brno Hotel Grand  Economy $49

Best Price Offer: The price for the cheapest bus from Karlsruhe to Brno is $43 on 4/28/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Karlsruhe and Brno

See here how frequent the connections between Karlsruhe and Brno are, during different times and days of the week.
Sunday is the busiest day, with more than 8 daily buses from Karlsruhe to Brno. Monday has instead the fewest connections, with only 2 daily coaches between Karlsruhe and Brno.
The busiest time of the day is the Morning, with 7 buses from Karlsruhe to Brno, while Evening sees the fewest connections between Karlsruhe and Brno, with 1 offers.

Facts about the bus from Karlsruhe to Brno

Compare all providers like FlixBus, Openline and Like Bus that travel 4 times every day by bus from Karlsruhe to Brno in one click! Book your bus ticket from Karlsruhe to Brno starting from $43!

Cheapest Bus $43
Fastest Bus 12h 30m
Earliest Bus 7:50 AM
Latest Bus 11:25 PM
Daily Bus Routes 4 Ø
Distance 371.3 miles
Bus Companies FlixBus, Openline and Like Bus

Cheapest bus connections from Karlsruhe to Brno

Every day, 4 buses from 3 bus companies leave Karlsruhe for Brno: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/19
Monday 04/20
$58
Tuesday 04/21
Wednesday 04/22
Thursday 04/23
Friday 04/24
Saturday 04/25
$58
Sunday 04/26
$49
Monday 04/27
$58
Tuesday 04/28
$43
Wednesday 04/29
$52
Thursday 04/30
Friday 05/01
$49
Saturday 05/02
Sunday 05/03
Monday 05/04
Tuesday 05/05
$51
Wednesday 05/06
Thursday 05/07
Friday 05/08
Saturday 05/09
Sunday 05/10
$55
Monday 05/11
Tuesday 05/12
$45
Wednesday 05/13
Thursday 05/14
Friday 05/15
$56
Saturday 05/16

The cheapest time to travel from Karlsruhe to Brno

See here on which day and which time of the day you can find the cheapest bus ticket from Karlsruhe to Brno, for the next 30 days.
With a price starting from $49, Sunday is the cheapest day for a bus from Karlsruhe to Brno. Monday instead is the most expensive day with prices starting from $58.
Night is the cheapest day time for bus tickets from Karlsruhe to Brno, with $43. Morning is the most expensive time of the day with prices starting from $49.

How to save money travelling from Karlsruhe to Brno

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlsruhe to Brno in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Brno, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Brno are also emptier.

All bus stations and stops in Karlsruhe and Brno

In the map below, you can see where to find all bus stations in Karlsruhe and Brno.

Service and Comfort on the bus from Karlsruhe to Brno

Want to know which seat classes are available on the buses from Karlsruhe to Brno? Or which bus companies serve the route Karlsruhe to Brno? Below you will find answers to your questions.

FAQs about the Karlsruhe to Brno bus

How much does a Karlsruhe Brno bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $43 and takes 12h 45m to reach Brno. Compare offers to save money!

How much could I save by comparing buses from Karlsruhe to Brno?

This route is offered by 3 companies with a range of ticket prices between $43 and $69. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brno.

On average, how many connections are available from Karlsruhe to Brno each day?

Every day, the Karlsruhe to Brno bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlsruhe to Brno take?

The fastest bus from Karlsruhe to Brno is offered by FlixBus and takes 12h 30m. Bus tickets for this connection cost $49. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlsruhe to Brno?

The earliest bus arriving in Brno from Karlsruhe starts at 7:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlsruhe to Brno?

The latest bus trip departing from Karlsruhe for Brno starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlsruhe Brno route?

When traveling by bus from Karlsruhe to Brno, passengers can travel with FlixBus, Openline and Like Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlsruhe and Brno?

You can check all the direct connections between Karlsruhe and Brno by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Openline and Like Bus.

What can I take with me on the Karlsruhe to Brno bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlsruhe Brno bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlsruhe Brno bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlsruhe to Brno on your planned travel date.

How does CheckMyBus find the best bus deals from Karlsruhe to Brno?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Karlsruhe and Brno. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Karlsruhe to Brno?

Prices and availability for 4 trips between Karlsruhe and Brno change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Karlsruhe to Brno

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlsruhe and to Brno

Here’s an overview of the most popular bus routes to Karlsruhe and to Brno. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Basel - Karlsruhe Buses Basel - Karlsruhe
Buses Zurich - Karlsruhe Buses Zurich - Karlsruhe
From Hanover to Karlsruhe bus From Hanover to Karlsruhe bus
Buses to Karlsruhe from Stuttgart Buses to Karlsruhe from Stuttgart
Bus Chernivtsi - Brno Bus Chernivtsi - Brno
Ostrava to Brno bus Ostrava to Brno bus
Bus Brest (BLR) to Brno Bus Brest (BLR) to Brno
Bus to Brno from Berlin Bus to Brno from Berlin
Popular Airport Shuttles to Karlsruhe and to Brno
CheckMyBus › Buses in Germany › Bus to Karlsruhe › Bus to Brno

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