Compare all timetables for the bus from Karlsruhe to Madrid
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $104 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/16/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/17/2026 1:20:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 26h 20m
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| FlixBus | 26h 20m | 6:35 AM | Karlsruhe | Central Station | 8:55 AM | Madrid | Sur Bus Station | Economy | $122 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/16/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/17/2026 8:55:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 26h 20m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $122 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/16/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/18/2026 7:55:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 32h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $120 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/20/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/21/2026 8:40:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 28h 35m
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| FlixBus | 34h 50m | 11:40 PM | Karlsruhe | Central Station | 10:30 AM | Madrid | Sur Bus Station | Economy | $140 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/20/2026 11:40:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/22/2026 10:30:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 34h 50m
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| FlixBus | 31h 20m | 12:35 AM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $149 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/20/2026 12:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/21/2026 7:55:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 31h 20m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $158 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/20/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/22/2026 7:55:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 32h 45m
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| FlixBus | 26h 20m | 6:35 AM | Karlsruhe | Central Station | 8:55 AM | Madrid | Sur Bus Station | Economy | $160 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/20/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/21/2026 8:55:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 26h 20m
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BlaBlaCar Bus27h 55m011:15 AMKarlsruheCentral Station1:05 PMStrasbourgPlace de l'Etoile0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 9/18/2026 11:15:00 AM to Place de l'Etoile, Strasbourg (France) arriving at 9/18/2026 1:05:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 50m
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BlaBlaCar Bus25h 0m02:10 PMStrasbourgPlace de l'Etoile3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Place de l'Etoile, Strasbourg (France) at 9/18/2026 2:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/19/2026 3:10:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 25h 0m
Waiting Time 1h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $99 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/21/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/22/2026 8:40:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 28h 35m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $105 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/21/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/23/2026 7:55:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 32h 45m
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| FlixBus | 34h 50m | 11:40 PM | Karlsruhe | Central Station | 10:30 AM | Madrid | Sur Bus Station | Economy | $116 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/21/2026 11:40:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/23/2026 10:30:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 34h 50m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $125 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/21/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/22/2026 1:20:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 26h 20m
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| FlixBus | 26h 20m | 6:35 AM | Karlsruhe | Central Station | 8:55 AM | Madrid | Sur Bus Station | Economy | $141 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/21/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/22/2026 8:55:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 26h 20m
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BlaBlaCar Bus27h 55m011:15 AMKarlsruheCentral Station1:05 PMStrasbourgPlace de l'Etoile0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 9/18/2026 11:15:00 AM to Place de l'Etoile, Strasbourg (France) arriving at 9/18/2026 1:05:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 50m
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BlaBlaCar Bus25h 0m02:10 PMStrasbourgPlace de l'Etoile3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Place de l'Etoile, Strasbourg (France) at 9/18/2026 2:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/19/2026 3:10:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 25h 0m
Waiting Time 1h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $88 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/22/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/23/2026 8:40:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 28h 35m
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| FlixBus | 27h 40m | 6:35 AM | Karlsruhe | Central Station | 10:15 AM | Madrid | Sur Bus Station | Economy | $89 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/22/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/23/2026 10:15:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 27h 40m
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| FlixBus | 26h 20m | 6:35 AM | Karlsruhe | Central Station | 8:55 AM | Madrid | Sur Bus Station | Economy | $99 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/22/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/23/2026 8:55:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 26h 20m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $99 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/22/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/24/2026 7:55:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 32h 45m
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| FlixBus | 31h 20m | 12:35 AM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $100 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 9/22/2026 12:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 9/23/2026 7:55:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 31h 20m
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BlaBlaCar Bus27h 55m011:15 AMKarlsruheCentral Station1:05 PMStrasbourgPlace de l'Etoile0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 9/18/2026 11:15:00 AM to Place de l'Etoile, Strasbourg (France) arriving at 9/18/2026 1:05:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 50m
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BlaBlaCar Bus25h 0m02:10 PMStrasbourgPlace de l'Etoile3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Place de l'Etoile, Strasbourg (France) at 9/18/2026 2:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 9/19/2026 3:10:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 25h 0m
Waiting Time 1h 5m -
Best Price Offer: The price for the cheapest bus from Karlsruhe to Madrid is $69 on 10/7/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Karlsruhe and Madrid
Facts about the bus from Karlsruhe to Madrid
Compare all providers like FlixBus that travel 5 times every day by bus from Karlsruhe to Madrid in one click! Book your bus ticket from Karlsruhe to Madrid starting from $69!
| Cheapest Bus | $69 |
| Fastest Bus | 26h 20m |
| Earliest Bus | 6:35 AM |
| Latest Bus | 11:10 PM |
| Daily Bus Routes | 5 Ø |
| Distance | 838.4 miles |
| Bus Companies | FlixBus |
Cheapest bus connections from Karlsruhe to Madrid
Every day, 5 buses from 1 bus companies leave Karlsruhe for Madrid: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/16/2026 and for the following days.
The cheapest time to travel from Karlsruhe to Madrid
How to save money travelling from Karlsruhe to Madrid
Book the ticket from Karlsruhe to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Madrid are also emptier.All bus stations and stops in Karlsruhe and Madrid
In the map below, you can see where to find all bus stations in Karlsruhe and Madrid.
Service and Comfort on the bus from Karlsruhe to Madrid
FAQs about the Karlsruhe to Madrid bus
How much does a Karlsruhe Madrid bus trip cost?
How much could I save by comparing buses from Karlsruhe to Madrid?
On average, how many connections are available from Karlsruhe to Madrid each day?
How long does a bus journey from Karlsruhe to Madrid take?
What time is the first bus from Karlsruhe to Madrid?
What time is the last bus from Karlsruhe to Madrid?
Which bus companies operate the Karlsruhe Madrid route?
Is there a direct bus between Karlsruhe and Madrid?
What can I take with me on the Karlsruhe to Madrid bus route?
What equipment is available for the Karlsruhe Madrid bus route?
How does CheckMyBus find the best bus deals from Karlsruhe to Madrid?
How does CheckMyBus technology work for trips from Karlsruhe to Madrid?
Available seat classes which are offered on the bus route Karlsruhe to Madrid
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Karlsruhe and to Madrid
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