Compare all timetables for the bus from Karlsruhe to Madrid
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $133 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 8:40:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 28h 35m
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| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $165 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 11:30:00 AM. 50 Economy ticket for $165 per person are available. Travel duration is 27h 20m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $189 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 1:20:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 26h 20m
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| FlixBus | 26h 20m | 6:35 AM | Karlsruhe | Central Station | 8:55 AM | Madrid | Sur Bus Station | Economy | $195 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 8:55:00 AM. 50 Economy ticket for $195 per person are available. Travel duration is 26h 20m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $201 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/2/2026 7:55:00 AM. 50 Economy ticket for $201 per person are available. Travel duration is 32h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $171 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/1/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/2/2026 8:40:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 28h 35m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $173 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/1/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/2/2026 1:20:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 26h 20m
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| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $175 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/1/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/2/2026 11:30:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 27h 20m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $199 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/1/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/3/2026 7:55:00 AM. 50 Economy ticket for $199 per person are available. Travel duration is 32h 45m
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| FlixBus | 26h 20m | 6:35 AM | Karlsruhe | Central Station | 8:55 AM | Madrid | Sur Bus Station | Economy | $209 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/1/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/2/2026 8:55:00 AM. 50 Economy ticket for $209 per person are available. Travel duration is 26h 20m
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FlixBus30h 40m07:25 AMKarlsruheCentral Station8:35 AMStrasbourgPlace de l'Etoile0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/2/2026 7:25:00 AM to Place de l'Etoile, Strasbourg (France) arriving at 8/2/2026 8:35:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 10m
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ALSA24h 55m01:10 PMStrasbourgPlace de l'Etoile2:05 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Place de l'Etoile, Strasbourg (France) at 8/2/2026 1:10:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 8/3/2026 2:05:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 24h 55m
Waiting Time 4h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $169 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/2/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/3/2026 8:40:00 AM. 50 Economy ticket for $169 per person are available. Travel duration is 28h 35m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $175 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/2/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/3/2026 1:20:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 26h 20m
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| BlaBlaCar Bus | 27h 35m | 9:05 PM | Karlsruhe | Central Station | 12:40 AM | Madrid | Sur Bus Station | Economy | $177 |
A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 8/2/2026 9:05:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/4/2026 12:40:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 27h 35m
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| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $182 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/2/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/3/2026 11:30:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 27h 20m
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| BlaBlaCar Bus | 26h 50m | 11:15 AM | Karlsruhe | Central Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $240 |
A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 8/2/2026 11:15:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/3/2026 2:05:00 PM. 50 Economy ticket for $240 per person are available. Travel duration is 26h 50m
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FlixBus30h 40m07:25 AMKarlsruheCentral Station8:35 AMStrasbourgPlace de l'Etoile0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/2/2026 7:25:00 AM to Place de l'Etoile, Strasbourg (France) arriving at 8/2/2026 8:35:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 10m
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ALSA24h 55m01:10 PMStrasbourgPlace de l'Etoile2:05 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Place de l'Etoile, Strasbourg (France) at 8/2/2026 1:10:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 8/3/2026 2:05:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 24h 55m
Waiting Time 4h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $137 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/3/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/4/2026 11:30:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 27h 20m
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| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $142 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/3/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/4/2026 8:40:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 28h 35m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $143 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/3/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/5/2026 7:55:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 32h 45m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $153 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/3/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/4/2026 1:20:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 26h 20m
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| FlixBus | 34h 50m | 11:40 PM | Karlsruhe | Central Station | 10:30 AM | Madrid | Sur Bus Station | Economy | $159 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/3/2026 11:40:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/5/2026 10:30:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 34h 50m
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BlaBlaCar Bus35h 35m09:05 PMKarlsruheCentral Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 8/4/2026 9:05:00 PM to Perrache Train Station, Lyon (France) arriving at 8/5/2026 5:10:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 5m
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FlixBus16h 40m04:00 PMLyonLyon Avenue Tony Garnier Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 8/5/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/6/2026 8:40:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 16h 40m
Waiting Time 10h 50m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $118 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/4/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/5/2026 11:30:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 27h 20m
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| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $122 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/4/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/5/2026 8:40:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 28h 35m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $136 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/4/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/5/2026 1:20:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 26h 20m
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| FlixBus | 27h 40m | 6:35 AM | Karlsruhe | Central Station | 10:15 AM | Madrid | Sur Bus Station | Economy | $143 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/4/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/5/2026 10:15:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 27h 40m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $148 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 8/4/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/6/2026 7:55:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 32h 45m
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BlaBlaCar Bus35h 35m09:05 PMKarlsruheCentral Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 8/4/2026 9:05:00 PM to Perrache Train Station, Lyon (France) arriving at 8/5/2026 5:10:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 5m
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FlixBus16h 40m04:00 PMLyonLyon Avenue Tony Garnier Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 8/5/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/6/2026 8:40:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 16h 40m
Waiting Time 10h 50m -
Best Price Offer: The price for the cheapest bus from Karlsruhe to Madrid is $98 on 7/28/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Karlsruhe and Madrid
Facts about the bus from Karlsruhe to Madrid
Compare all providers like FlixBus and BlaBlaCar Bus that travel 8 times every day by bus from Karlsruhe to Madrid in one click! Book your bus ticket from Karlsruhe to Madrid starting from $98!
| Cheapest Bus | $98 |
| Fastest Bus | 26h 20m |
| Earliest Bus | 12:35 AM |
| Latest Bus | 11:10 PM |
| Daily Bus Routes | 8 Ø |
| Distance | 838.4 miles |
| Bus Companies | FlixBus and BlaBlaCar Bus |
Cheapest bus connections from Karlsruhe to Madrid
Every day, 8 buses from 2 bus companies leave Karlsruhe for Madrid: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/30/2026 and for the following days.
The cheapest time to travel from Karlsruhe to Madrid
How to save money travelling from Karlsruhe to Madrid
Book the ticket from Karlsruhe to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Madrid are also emptier.All bus stations and stops in Karlsruhe and Madrid
In the map below, you can see where to find all bus stations in Karlsruhe and Madrid.
Service and Comfort on the bus from Karlsruhe to Madrid
FAQs about the Karlsruhe to Madrid bus
How much does a Karlsruhe Madrid bus trip cost?
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On average, how many connections are available from Karlsruhe to Madrid each day?
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What time is the first bus from Karlsruhe to Madrid?
What time is the last bus from Karlsruhe to Madrid?
Which bus companies operate the Karlsruhe Madrid route?
Is there a direct bus between Karlsruhe and Madrid?
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What equipment is available for the Karlsruhe Madrid bus route?
How does CheckMyBus find the best bus deals from Karlsruhe to Madrid?
How does CheckMyBus technology work for trips from Karlsruhe to Madrid?
Available seat classes which are offered on the bus route Karlsruhe to Madrid
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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