Bus Karlsruhe to Milan - Compare all Companies

Compare all timetables for the bus from Karlsruhe to Milan

Here is a selection of the cheapest bus trips from the schedule from Karlsruhe to Milan from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

$41

tomorrow

$44

Thursday

$41

Friday

$40

Saturday

$39

Sunday

$40

Monday

$40

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station		Economy	$41	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/5/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/6/2026 5:05:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 55m
	FlixBus	8h 10m	11:00 PM	Karlsruhe	Central Station	7:10 AM	Milan	Lampugnano Bus Station		Economy	$72	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/5/2026 11:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/6/2026 7:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 8h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/6/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/6/2026 4:50:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 7h 20m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$46	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/6/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/6/2026 7:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 8h 10m
FlixBus	7h 55m	3:20 AM	Karlsruhe	Central Station	11:15 AM	Milan	Lampugnano Bus Station	Economy	$48	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/6/2026 3:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/6/2026 11:15:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 7h 55m
FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station	Economy	$49	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/6/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/7/2026 5:05:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 8h 55m
FlixBus	8h 10m	11:00 PM	Karlsruhe	Central Station	7:10 AM	Milan	Lampugnano Bus Station	Economy	$98	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/6/2026 11:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/7/2026 7:10:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 8h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$41	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/7/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/7/2026 4:50:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 7h 20m
FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station	Economy	$42	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/7/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/8/2026 5:05:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 55m
FlixBus	8h 25m	11:40 PM	Karlsruhe	Central Station	8:05 AM	Milan	Lampugnano Bus Station	Economy	$54	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/7/2026 11:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/8/2026 8:05:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 8h 25m
FlixBus	7h 55m	3:20 AM	Karlsruhe	Central Station	11:15 AM	Milan	Lampugnano Bus Station	Economy	$61	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/7/2026 3:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/7/2026 11:15:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 7h 55m
FlixBus	8h 10m	11:00 PM	Karlsruhe	Central Station	7:10 AM	Milan	Lampugnano Bus Station	Economy	$72	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/7/2026 11:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/8/2026 7:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 8h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	17h 0m	9:05 PM	Karlsruhe	Central Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 5/8/2026 9:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 2:05:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 17h 0m
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$47	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/8/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/8/2026 4:50:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 7h 20m
FlixBus	8h 25m	11:40 PM	Karlsruhe	Central Station	8:05 AM	Milan	Lampugnano Bus Station	Economy	$47	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/8/2026 11:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 8:05:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 25m
FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station	Economy	$49	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/8/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 5:05:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 8h 55m
BlaBlaCar Bus	18h 45m	11:15 AM	Karlsruhe	Central Station	6:00 AM	Milan	Lampugnano Bus Station	Economy	$74	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 5/8/2026 11:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 6:00:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 18h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	17h 0m	9:05 PM	Karlsruhe	Central Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$39	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 5/9/2026 9:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/10/2026 2:05:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 17h 0m
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/9/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 4:50:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 20m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/9/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 7:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 10m
FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station	Economy	$42	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/9/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/10/2026 5:05:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 55m
BlaBlaCar Bus	21h 0m	12:25 AM	Karlsruhe	Central Station	9:25 PM	Milan	Lampugnano Bus Station	Economy	$105	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 5/9/2026 12:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 9:25:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 21h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	17h 0m	9:05 PM	Karlsruhe	Central Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 5/10/2026 9:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/11/2026 2:05:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 17h 0m
FlixBus	7h 55m	3:20 AM	Karlsruhe	Central Station	11:15 AM	Milan	Lampugnano Bus Station	Economy	$47	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/10/2026 3:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/10/2026 11:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 7h 55m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$47	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/10/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/10/2026 7:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 10m
FlixBus	8h 25m	11:40 PM	Karlsruhe	Central Station	8:05 AM	Milan	Lampugnano Bus Station	Economy	$48	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/10/2026 11:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/11/2026 8:05:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 8h 25m
BlaBlaCar Bus	21h 0m	12:25 AM	Karlsruhe	Central Station	9:25 PM	Milan	Lampugnano Bus Station	Economy	$78	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 5/10/2026 12:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/10/2026 9:25:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 21h 0m

Did you know that if you travel from Karlsruhe to Milan via Zurich, you can save more than $8? You can find the corresponding connections below.
- FlixBus
  
  11h 25m
  
  0
  
  11:05 AM
  
  Karlsruhe
  Central Station
  
  3:10 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $19
  
  A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/9/2026 11:05:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 5/9/2026 3:10:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 5m
- Itabus
  
  5h 10m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  10:30 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Basic
  
  $13
  
  A Bus from Itabus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 5/9/2026 5:20:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 5/9/2026 10:30:00 PM. 50 Basic ticket for $13 per person are available. Travel duration is 5h 10m
Travel time is 3h 30m longer, but you will save $8

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/11/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/11/2026 4:50:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 20m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$41	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/11/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/11/2026 7:15:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 10m
FlixBus	7h 55m	3:20 AM	Karlsruhe	Central Station	11:15 AM	Milan	Lampugnano Bus Station	Economy	$42	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 5/11/2026 3:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/11/2026 11:15:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 7h 55m
BlaBlaCar Bus	21h 0m	12:25 AM	Karlsruhe	Central Station	9:25 PM	Milan	Lampugnano Bus Station	Economy	$88	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 5/11/2026 12:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 5/11/2026 9:25:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 21h 0m

Best Price Offer: The price for the cheapest bus from Karlsruhe to Milan is $36 on 5/12/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Karlsruhe and Milan

See here how frequent the connections between Karlsruhe and Milan are, during different times and days of the week.

Sunday is the busiest day, with more than 10 daily buses from Karlsruhe to Milan. Tuesday has instead the fewest connections, with only 2 daily coaches between Karlsruhe and Milan.

The busiest time of the day is the Evening, with 22 buses from Karlsruhe to Milan, while Night sees the fewest connections between Karlsruhe and Milan, with 10 offers.

Facts about the bus from Karlsruhe to Milan

Compare all providers like FlixBus and BlaBlaCar Bus that travel 7 times every day by bus from Karlsruhe to Milan in one click! Book your bus ticket from Karlsruhe to Milan starting from $36!

Cheapest Bus	$36
Fastest Bus	7h 20m
Earliest Bus	8:10 PM
Latest Bus	11:40 PM
Daily Bus Routes	7 Ø
Distance	247.5 miles
Bus Companies	FlixBus and BlaBlaCar Bus

Cheapest bus connections from Karlsruhe to Milan

Every day, 7 buses from 2 bus companies leave Karlsruhe for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

$37

Wednesday 05/06

$44

Thursday 05/07

$41

Friday 05/08

$40

Saturday 05/09

$39

Sunday 05/10

$40

Monday 05/11

$40

Tuesday 05/12

$36

Wednesday 05/13

$40

Thursday 05/14

$42

Friday 05/15

$42

Saturday 05/16

$41

Sunday 05/17

$44

Monday 05/18

$37

Tuesday 05/19

$36

Wednesday 05/20

$39

Thursday 05/21

$41

Friday 05/22

$55

Saturday 05/23

$42

Sunday 05/24

$37

Monday 05/25

$51

Tuesday 05/26

$48

Wednesday 05/27

$44

Thursday 05/28

$42

Friday 05/29

$44

Saturday 05/30

The cheapest time to travel from Karlsruhe to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Karlsruhe to Milan, for the next 30 days.

With a price starting from $36, Tuesday is the cheapest day for a bus from Karlsruhe to Milan. Thursday instead is the most expensive day with prices starting from $41.

Night is the cheapest day time for bus tickets from Karlsruhe to Milan, with $36. Morning is the most expensive time of the day with prices starting from $40.

How to save money travelling from Karlsruhe to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlsruhe to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Milan are also emptier.

All bus stations and stops in Karlsruhe and Milan

In the map below, you can see where to find all bus stations in Karlsruhe and Milan.

Central Bus Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Bannwaldallee Station

Kühler Krug Train Station

Sudetenstraße Bus Stop

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Service and Comfort on the bus from Karlsruhe to Milan

Want to know which seat classes are available on the buses from Karlsruhe to Milan? Or which bus companies serve the route Karlsruhe to Milan? Below you will find answers to your questions.

FAQs about the Karlsruhe to Milan bus

How much does a Karlsruhe Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $36 and takes 17h 0m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Karlsruhe to Milan?

This route is offered by 2 companies with a range of ticket prices between $36 and $105. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Karlsruhe to Milan each day?

Every day, the Karlsruhe to Milan bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlsruhe to Milan take?

The fastest bus from Karlsruhe to Milan is offered by FlixBus and takes 7h 20m. Bus tickets for this connection cost $44. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlsruhe to Milan?

The earliest bus arriving in Milan from Karlsruhe starts at 8:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlsruhe to Milan?

The latest bus trip departing from Karlsruhe for Milan starts at 11:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlsruhe Milan route?

When traveling by bus from Karlsruhe to Milan, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlsruhe and Milan?

You can check all the direct connections between Karlsruhe and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Karlsruhe to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlsruhe Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlsruhe Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlsruhe to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Karlsruhe to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Karlsruhe and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Karlsruhe to Milan?

Prices and availability for 7 trips between Karlsruhe and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Karlsruhe to Milan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlsruhe and to Milan

Here’s an overview of the most popular bus routes to Karlsruhe and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!