Bus Karlsruhe to Prague - Compare all Companies

Compare all timetables for the bus from Karlsruhe to Prague

Here is a selection of the cheapest bus trips from the schedule from Karlsruhe to Prague from various bus operators like FlixBus for the next days.

today

$50

tomorrow

$38

Sunday

$44

Monday

$34

Tuesday

$31

Wednesday

$34

Thursday

$37

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 0m	4:15 PM	Karlsruhe	Central Station	3:15 AM	Prague	Wilsonova Bus Station	Economy	$50	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 4:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/6/2025 3:15:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 11h 0m
FlixBus	9h 0m	11:30 PM	Karlsruhe	Central Station	8:30 AM	Prague	Zličín	Economy	$52	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 11:30:00 PM to Zličín, Prague (Czech Republic) arriving at 12/6/2025 8:30:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 9h 0m
FlixBus	10h 25m	12:15 PM	Karlsruhe	Central Station	10:40 PM	Prague	ÚAN Florenc	Economy	$54	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 12:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/5/2025 10:40:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 10h 25m
FlixBus	8h 30m	1:20 PM	Karlsruhe	Central Station	9:50 PM	Prague	ÚAN Florenc	Economy	$54	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 1:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/5/2025 9:50:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 8h 30m
FlixBus	11h 40m	6:20 PM	Karlsruhe	Central Station	6:00 AM	Prague	Wilsonova Bus Station	Economy	$55	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 6:20:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/6/2025 6:00:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 11h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	9h 0m	6:25 AM	Karlsruhe	Central Station	3:25 PM	Prague	ÚAN Florenc	Economy	$38	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 6:25:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/6/2025 3:25:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 9h 0m
FlixBus	8h 30m	1:20 PM	Karlsruhe	Central Station	9:50 PM	Prague	ÚAN Florenc	Economy	$38	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 1:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/6/2025 9:50:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 8h 30m
FlixBus	9h 45m	6:25 AM	Karlsruhe	Central Station	4:10 PM	Prague	Černý Most	Economy	$38	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 6:25:00 AM to Černý Most, Prague (Czech Republic) arriving at 12/6/2025 4:10:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 9h 45m
FlixBus	10h 50m	3:05 AM	Karlsruhe	Central Station	1:55 PM	Prague	Wilsonova Bus Station	Economy	$43	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 3:05:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/6/2025 1:55:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 50m
FlixBus	10h 30m	11:45 AM	Karlsruhe	Central Station	10:15 PM	Prague	Wilsonova Bus Station	Economy	$43	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 11:45:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/6/2025 10:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	9h 0m	6:25 AM	Karlsruhe	Central Station	3:25 PM	Prague	ÚAN Florenc	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 6:25:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/7/2025 3:25:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 0m
FlixBus	8h 30m	1:20 PM	Karlsruhe	Central Station	9:50 PM	Prague	ÚAN Florenc	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 1:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/7/2025 9:50:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 30m
FlixBus	8h 25m	11:30 PM	Karlsruhe	Central Station	7:55 AM	Prague	ÚAN Florenc	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/8/2025 7:55:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 25m
FlixBus	9h 45m	6:25 AM	Karlsruhe	Central Station	4:10 PM	Prague	Černý Most	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 6:25:00 AM to Černý Most, Prague (Czech Republic) arriving at 12/7/2025 4:10:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 45m
FlixBus	8h 10m	11:30 PM	Karlsruhe	Central Station	7:40 AM	Prague	Na Knížecí Station	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 11:30:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/8/2025 7:40:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	9h 0m	6:25 AM	Karlsruhe	Central Station	3:25 PM	Prague	ÚAN Florenc	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/8/2025 6:25:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/8/2025 3:25:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 0m
FlixBus	8h 30m	1:20 PM	Karlsruhe	Central Station	9:50 PM	Prague	ÚAN Florenc	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/8/2025 1:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/8/2025 9:50:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 30m
FlixBus	9h 45m	6:25 AM	Karlsruhe	Central Station	4:10 PM	Prague	Černý Most	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/8/2025 6:25:00 AM to Černý Most, Prague (Czech Republic) arriving at 12/8/2025 4:10:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 45m
FlixBus	10h 30m	12:05 AM	Karlsruhe	Central Station	10:35 AM	Prague	Wilsonova Bus Station	Economy	$36	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/8/2025 12:05:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/8/2025 10:35:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 30m
FlixBus	10h 25m	4:55 AM	Karlsruhe	Central Station	3:20 PM	Prague	Wilsonova Bus Station	Economy	$36	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/8/2025 4:55:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/8/2025 3:20:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	9h 0m	6:25 AM	Karlsruhe	Central Station	3:25 PM	Prague	ÚAN Florenc	Economy	$31	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 6:25:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/9/2025 3:25:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 9h 0m
FlixBus	8h 30m	1:20 PM	Karlsruhe	Central Station	9:50 PM	Prague	ÚAN Florenc	Economy	$31	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 1:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 8h 30m
FlixBus	9h 45m	6:25 AM	Karlsruhe	Central Station	4:10 PM	Prague	Černý Most	Economy	$31	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 6:25:00 AM to Černý Most, Prague (Czech Republic) arriving at 12/9/2025 4:10:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 9h 45m
FlixBus	10h 25m	4:55 AM	Karlsruhe	Central Station	3:20 PM	Prague	Wilsonova Bus Station	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 4:55:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/9/2025 3:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 25m
FlixBus	11h 45m	8:35 AM	Karlsruhe	Central Station	8:20 PM	Prague	Na Knížecí Station	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 8:35:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/9/2025 8:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 11h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 25m	11:30 PM	Karlsruhe	Central Station	7:55 AM	Prague	ÚAN Florenc	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/11/2025 7:55:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 25m
FlixBus	8h 10m	11:30 PM	Karlsruhe	Central Station	7:40 AM	Prague	Na Knížecí Station	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 11:30:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/11/2025 7:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 10m
FlixBus	11h 30m	2:25 AM	Karlsruhe	Central Station	1:55 PM	Prague	Wilsonova Bus Station	Economy	$35	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 2:25:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/10/2025 1:55:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 11h 30m
FlixBus	10h 25m	4:55 AM	Karlsruhe	Central Station	3:20 PM	Prague	Wilsonova Bus Station	Economy	$35	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 4:55:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/10/2025 3:20:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 10h 25m
FlixBus	11h 5m	11:30 PM	Karlsruhe	Central Station	10:35 AM	Prague	Wilsonova Bus Station	Economy	$35	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 11:30:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/11/2025 10:35:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 11h 5m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 55m	8:35 AM	Karlsruhe	Central Station	5:30 PM	Prague	Wilsonova Bus Station	Economy	$37	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 8:35:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/11/2025 5:30:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 8h 55m
FlixBus	9h 10m	8:35 AM	Karlsruhe	Central Station	5:45 PM	Prague	ÚAN Florenc	Economy	$37	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 8:35:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/11/2025 5:45:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 9h 10m
FlixBus	10h 25m	4:55 AM	Karlsruhe	Central Station	3:20 PM	Prague	Wilsonova Bus Station	Economy	$39	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 4:55:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/11/2025 3:20:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 10h 25m
FlixBus	11h 0m	4:15 PM	Karlsruhe	Central Station	3:15 AM	Prague	Wilsonova Bus Station	Economy	$39	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 4:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/12/2025 3:15:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 11h 0m
FlixBus	11h 40m	6:20 PM	Karlsruhe	Central Station	6:00 AM	Prague	Wilsonova Bus Station	Economy	$39	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 6:20:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/12/2025 6:00:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 11h 40m

Best Price Offer: The price for the cheapest bus from Karlsruhe to Prague is $31 on 12/1/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Karlsruhe and Prague

See here how frequent the connections between Karlsruhe and Prague are, during different times and days of the week.

Saturday is the busiest day, with more than 24 daily buses from Karlsruhe to Prague. Wednesday has instead the fewest connections, with only 14 daily coaches between Karlsruhe and Prague.

The busiest time of the day is the Evening, with 40 buses from Karlsruhe to Prague, while Night sees the fewest connections between Karlsruhe and Prague, with 33 offers.

Facts about the bus from Karlsruhe to Prague

Compare all providers like FlixBus that travel 20 times every day by bus from Karlsruhe to Prague in one click! Book your bus ticket from Karlsruhe to Prague starting from $31!

Cheapest Bus	$31
Fastest Bus	8h 10m
Earliest Bus	12:05 AM
Latest Bus	11:30 PM
Daily Bus Routes	20 Ø
Distance	280.4 miles
Bus Companies	FlixBus

Cheapest bus connections from Karlsruhe to Prague

Every day, 20 buses from 1 bus companies leave Karlsruhe for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$50

Saturday 12/06

$38

Sunday 12/07

$44

Monday 12/08

$34

Tuesday 12/09

$31

Wednesday 12/10

$34

Thursday 12/11

$37

Friday 12/12

$36

Saturday 12/13

Sunday 12/14

$36

Monday 12/15

$36

Tuesday 12/16

$36

Wednesday 12/17

$37

Thursday 12/18

$41

Friday 12/19

$55

Saturday 12/20

$63

Sunday 12/21

$63

Monday 12/22

$53

Tuesday 12/23

$54

Wednesday 12/24

$52

Thursday 12/25

$54

Friday 12/26

$63

Saturday 12/27

The cheapest time to travel from Karlsruhe to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Karlsruhe to Prague, for the next 30 days.

With a price starting from $31, Tuesday is the cheapest day for a bus from Karlsruhe to Prague. Saturday instead is the most expensive day with prices starting from $38.

Morning is the cheapest day time for bus tickets from Karlsruhe to Prague, with $31. Evening is the most expensive time of the day with prices starting from $34.

How to save money travelling from Karlsruhe to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlsruhe to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Prague are also emptier.

All bus stations and stops in Karlsruhe and Prague

In the map below, you can see where to find all bus stations in Karlsruhe and Prague.

Central Bus Station

Central Station

Hinterm Hauptbahnhof 6

Durlach Train Station

Knielingen Train Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Bus Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Hradčanská

Milady Horákové 115/107

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Karlsruhe to Prague? Compare all modes of transports from Karlsruhe to Prague.

Service and Comfort on the bus from Karlsruhe to Prague

Want to know which seat classes are available on the buses from Karlsruhe to Prague? Or which bus companies serve the route Karlsruhe to Prague? Below you will find answers to your questions.

FAQs about the Karlsruhe to Prague bus

How much does a Karlsruhe Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $31 and takes 9h 0m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Karlsruhe to Prague?

This route is offered by 1 companies with a range of ticket prices between $31 and $91. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Karlsruhe to Prague each day?

Every day, the Karlsruhe to Prague bus route is served by approximately 20 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlsruhe to Prague take?

The fastest bus from Karlsruhe to Prague is offered by FlixBus and takes 8h 10m. Bus tickets for this connection cost $57. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlsruhe to Prague?

The earliest bus arriving in Prague from Karlsruhe starts at 12:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlsruhe to Prague?

The latest bus trip departing from Karlsruhe for Prague starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlsruhe Prague route?

When traveling by bus from Karlsruhe to Prague, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlsruhe and Prague?

You can check all the direct connections between Karlsruhe and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Karlsruhe to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlsruhe Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlsruhe Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlsruhe to Prague on your planned travel date.

Available seat classes which are offered on the bus route Karlsruhe to Prague

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlsruhe and to Prague

Here’s an overview of the most popular bus routes to Karlsruhe and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!