Bus La Serena to Talca, ML - Compare all Companies

Compare all timetables for the bus from La Serena to Talca, ML

Here is a selection of the cheapest bus trips from the schedule from La Serena to Talca, ML from various bus operators like Turbus or FlixBus for the next days.

today

$34

tomorrow

$34

Wednesday

$32

Thursday

$34

Friday

$30

Saturday

$30

Sunday

$25

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	9h 40m	9:00 AM	La Serena	Avda. Fco de Aguirre Station	6:40 PM	Talca, ML	Central Bus Station	First Class	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/20/2026 9:00:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/20/2026 6:40:00 PM. 50 First Class ticket for $34 per person are available. Travel duration is 9h 40m
Turbus	10h 5m	11:30 PM	La Serena	Avda. Fco de Aguirre Station	9:35 AM	Talca, ML	Central Bus Station	First Class	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/20/2026 11:30:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/21/2026 9:35:00 AM. 50 First Class ticket for $34 per person are available. Travel duration is 10h 5m
Turbus	10h 40m	8:20 AM	La Serena	Avda. Fco de Aguirre Station	7:00 PM	Talca, ML	Central Bus Station	Premium Economy	$42	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/20/2026 8:20:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/20/2026 7:00:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 10h 40m
Turbus	9h 50m	11:55 PM	La Serena	Avda. Fco de Aguirre Station	9:45 AM	Talca, ML	Central Bus Station	Premium Economy	$42	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/20/2026 11:55:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/21/2026 9:45:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 9h 50m
Turbus	10h 15m	5:15 PM	La Serena	Avda. Fco de Aguirre Station	3:30 AM	Talca, ML	Terminal	First Class	$55	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/20/2026 5:15:00 PM to Terminal, Talca, ML (Chile) arriving at 4/21/2026 3:30:00 AM. 50 First Class ticket for $55 per person are available. Travel duration is 10h 15m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	9h 40m	9:00 AM	La Serena	Avda. Fco de Aguirre Station	6:40 PM	Talca, ML	Central Bus Station	First Class	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/21/2026 9:00:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/21/2026 6:40:00 PM. 50 First Class ticket for $34 per person are available. Travel duration is 9h 40m
Turbus	10h 5m	11:30 PM	La Serena	Avda. Fco de Aguirre Station	9:35 AM	Talca, ML	Central Bus Station	First Class	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/21/2026 11:30:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/22/2026 9:35:00 AM. 50 First Class ticket for $34 per person are available. Travel duration is 10h 5m
Turbus	10h 40m	8:20 AM	La Serena	Avda. Fco de Aguirre Station	7:00 PM	Talca, ML	Central Bus Station	Premium Economy	$42	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/21/2026 8:20:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/21/2026 7:00:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 10h 40m
Turbus	9h 50m	11:55 PM	La Serena	Avda. Fco de Aguirre Station	9:45 AM	Talca, ML	Central Bus Station	Premium Economy	$42	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/21/2026 11:55:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/22/2026 9:45:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 9h 50m
Turbus	10h 15m	5:15 PM	La Serena	Avda. Fco de Aguirre Station	3:30 AM	Talca, ML	Terminal	First Class	$55	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/21/2026 5:15:00 PM to Terminal, Talca, ML (Chile) arriving at 4/22/2026 3:30:00 AM. 50 First Class ticket for $55 per person are available. Travel duration is 10h 15m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	9h 55m	12:30 AM	La Serena	Avda. Fco de Aguirre Station	10:25 AM	Talca, ML	Central Bus Station	Premium Economy	$32	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/22/2026 12:30:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/22/2026 10:25:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 9h 55m
Turbus	10h 40m	8:20 AM	La Serena	Avda. Fco de Aguirre Station	7:00 PM	Talca, ML	Central Bus Station	Premium Economy	$32	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/22/2026 8:20:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/22/2026 7:00:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 40m
Turbus	9h 50m	11:55 PM	La Serena	Avda. Fco de Aguirre Station	9:45 AM	Talca, ML	Central Bus Station	Premium Economy	$32	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/22/2026 11:55:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/23/2026 9:45:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 9h 50m
FlixBus	10h 50m	3:20 AM	La Serena	Central Bus Station	2:10 PM	Talca, ML	Cruce Varoli	Economy	$41	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 4/22/2026 3:20:00 AM to Cruce Varoli, Talca, ML (Chile) arriving at 4/22/2026 2:10:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 10h 50m
FlixBus	14h 20m	11:50 PM	La Serena	Central Bus Station	2:10 PM	Talca, ML	Cruce Varoli	Economy	$41	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 4/22/2026 11:50:00 PM to Cruce Varoli, Talca, ML (Chile) arriving at 4/23/2026 2:10:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 14h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	9h 40m	9:00 AM	La Serena	Avda. Fco de Aguirre Station	6:40 PM	Talca, ML	Central Bus Station	First Class	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/23/2026 9:00:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/23/2026 6:40:00 PM. 50 First Class ticket for $34 per person are available. Travel duration is 9h 40m
Turbus	10h 5m	11:30 PM	La Serena	Avda. Fco de Aguirre Station	9:35 AM	Talca, ML	Central Bus Station	First Class	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/23/2026 11:30:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/24/2026 9:35:00 AM. 50 First Class ticket for $34 per person are available. Travel duration is 10h 5m
Turbus	9h 55m	12:30 AM	La Serena	Avda. Fco de Aguirre Station	10:25 AM	Talca, ML	Central Bus Station	Premium Economy	$42	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/23/2026 12:30:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/23/2026 10:25:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 9h 55m
Turbus	10h 40m	8:20 AM	La Serena	Avda. Fco de Aguirre Station	7:00 PM	Talca, ML	Central Bus Station	Premium Economy	$42	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/23/2026 8:20:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/23/2026 7:00:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 10h 40m
Turbus	9h 50m	11:55 PM	La Serena	Avda. Fco de Aguirre Station	9:45 AM	Talca, ML	Central Bus Station	Premium Economy	$42	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/23/2026 11:55:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/24/2026 9:45:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 9h 50m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 10m	10:00 AM	La Serena	Central Bus Station	9:10 PM	Talca, ML	Cruce Varoli	Economy	$30	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 4/24/2026 10:00:00 AM to Cruce Varoli, Talca, ML (Chile) arriving at 4/24/2026 9:10:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 11h 10m
Turbus	9h 40m	9:00 AM	La Serena	Avda. Fco de Aguirre Station	6:40 PM	Talca, ML	Central Bus Station	First Class	$38	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/24/2026 9:00:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/24/2026 6:40:00 PM. 50 First Class ticket for $38 per person are available. Travel duration is 9h 40m
Turbus	10h 5m	11:30 PM	La Serena	Avda. Fco de Aguirre Station	9:35 AM	Talca, ML	Central Bus Station	First Class	$38	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/24/2026 11:30:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/25/2026 9:35:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 10h 5m
FlixBus	14h 20m	11:50 PM	La Serena	Central Bus Station	2:10 PM	Talca, ML	Cruce Varoli	Economy	$39	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 4/24/2026 11:50:00 PM to Cruce Varoli, Talca, ML (Chile) arriving at 4/25/2026 2:10:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 14h 20m
FlixBus	10h 50m	3:20 AM	La Serena	Central Bus Station	2:10 PM	Talca, ML	Cruce Varoli	Economy	$40	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 4/24/2026 3:20:00 AM to Cruce Varoli, Talca, ML (Chile) arriving at 4/24/2026 2:10:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 10h 50m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	10h 40m	8:20 AM	La Serena	Avda. Fco de Aguirre Station	7:00 PM	Talca, ML	Central Bus Station	Premium Economy	$30	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/25/2026 8:20:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/25/2026 7:00:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 10h 40m
Turbus	9h 50m	11:55 PM	La Serena	Avda. Fco de Aguirre Station	9:45 AM	Talca, ML	Central Bus Station	Premium Economy	$30	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/25/2026 11:55:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/26/2026 9:45:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 9h 50m
FlixBus	11h 10m	10:00 AM	La Serena	Central Bus Station	9:10 PM	Talca, ML	Cruce Varoli	Economy	$30	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 4/25/2026 10:00:00 AM to Cruce Varoli, Talca, ML (Chile) arriving at 4/25/2026 9:10:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 11h 10m
Turbus	9h 40m	9:00 AM	La Serena	Avda. Fco de Aguirre Station	6:40 PM	Talca, ML	Central Bus Station	First Class	$36	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/25/2026 9:00:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/25/2026 6:40:00 PM. 50 First Class ticket for $36 per person are available. Travel duration is 9h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 10m	10:00 AM	La Serena	Central Bus Station	9:10 PM	Talca, ML	Cruce Varoli	Economy	$25	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 4/26/2026 10:00:00 AM to Cruce Varoli, Talca, ML (Chile) arriving at 4/26/2026 9:10:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 11h 10m
Turbus	9h 55m	12:30 AM	La Serena	Avda. Fco de Aguirre Station	10:25 AM	Talca, ML	Central Bus Station	Premium Economy	$30	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/26/2026 12:30:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/26/2026 10:25:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 9h 55m
Turbus	10h 40m	8:20 AM	La Serena	Avda. Fco de Aguirre Station	7:00 PM	Talca, ML	Central Bus Station	Premium Economy	$37	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/26/2026 8:20:00 AM to Central Bus Station, Talca, ML (Chile) arriving at 4/26/2026 7:00:00 PM. 50 Premium Economy ticket for $37 per person are available. Travel duration is 10h 40m
Turbus	9h 50m	11:55 PM	La Serena	Avda. Fco de Aguirre Station	9:45 AM	Talca, ML	Central Bus Station	Premium Economy	$37	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 4/26/2026 11:55:00 PM to Central Bus Station, Talca, ML (Chile) arriving at 4/27/2026 9:45:00 AM. 50 Premium Economy ticket for $37 per person are available. Travel duration is 9h 50m

Best Price Offer: The price for the cheapest bus from La Serena to Talca, ML is $21 on 5/11/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between La Serena and Talca, ML

See here how frequent the connections between La Serena and Talca, ML are, during different times and days of the week.

Friday is the busiest day, with more than 10 daily buses from La Serena to Talca, ML. Monday has instead the fewest connections, with only 6 daily coaches between La Serena and Talca, ML.

The busiest time of the day is the Evening, with 23 buses from La Serena to Talca, ML, while Afternoon sees the fewest connections between La Serena and Talca, ML, with 7 offers.

Facts about the bus from La Serena to Talca, ML

Compare all providers like Turbus and FlixBus that travel 7 times every day by bus from La Serena to Talca, ML in one click! Book your bus ticket from La Serena to Talca, ML starting from $21!

Cheapest Bus	$21
Fastest Bus	9h 40m
Earliest Bus	8:20 AM
Latest Bus	11:55 PM
Daily Bus Routes	7 Ø
Distance	382.3 miles
Bus Companies	Turbus and FlixBus

Cheapest bus connections from La Serena to Talca, ML

Every day, 7 buses from 2 bus companies leave La Serena for Talca, ML: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$34

Tuesday 04/21

$36

Wednesday 04/22

$32

Thursday 04/23

$34

Friday 04/24

$30

Saturday 04/25

$30

Sunday 04/26

$25

Monday 04/27

$37

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

$37

Friday 05/01

$35

Saturday 05/02

$22

Sunday 05/03

$41

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$21

Saturday 05/09

$22

Sunday 05/10

$23

Monday 05/11

$21

Tuesday 05/12

$25

Wednesday 05/13

$32

Thursday 05/14

$25

Friday 05/15

$32

Saturday 05/16

The cheapest time to travel from La Serena to Talca, ML

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Talca, ML, for the next 30 days.

With a price starting from $21, Monday is the cheapest day for a bus from La Serena to Talca, ML. Wednesday instead is the most expensive day with prices starting from $32.

Night is the cheapest day time for bus tickets from La Serena to Talca, ML, with $21. Afternoon is the most expensive time of the day with prices starting from $36.

How to save money travelling from La Serena to Talca, ML

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from La Serena to Talca, ML in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from La Serena to Talca, ML, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from La Serena to Talca, ML are also emptier.

All bus stations and stops in La Serena and Talca, ML

In the map below, you can see where to find all bus stations in La Serena and Talca, ML.

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Bus Station

Avenida El Santo 1475

El Sto, 1060

Rotonda

terminal de buses covalle bus

Central Bus Station

Dos Sur 1932

Cruce Varoli

Calle 1 Norte / 18 ote

Terminal

Cruce Ruta 5

Service and Comfort on the bus from La Serena to Talca, ML

Want to know which seat classes are available on the buses from La Serena to Talca, ML? Or which bus companies serve the route La Serena to Talca, ML? Below you will find answers to your questions.

FAQs about the La Serena to Talca, ML bus

How much does a La Serena Talca, ML bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $21 and takes 11h 10m to reach Talca, ML. Compare offers to save money!

How much could I save by comparing buses from La Serena to Talca, ML?

This route is offered by 2 companies with a range of ticket prices between $21 and $55. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Talca, ML.

On average, how many connections are available from La Serena to Talca, ML each day?

Every day, the La Serena to Talca, ML bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from La Serena to Talca, ML take?

The fastest bus from La Serena to Talca, ML is offered by Turbus and takes 9h 40m. Bus tickets for this connection cost $34. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from La Serena to Talca, ML?

The earliest bus arriving in Talca, ML from La Serena starts at 8:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from La Serena to Talca, ML?

The latest bus trip departing from La Serena for Talca, ML starts at 11:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the La Serena Talca, ML route?

When traveling by bus from La Serena to Talca, ML, passengers can travel with Turbus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between La Serena and Talca, ML?

You can check all the direct connections between La Serena and Talca, ML by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Turbus and FlixBus.

What can I take with me on the La Serena to Talca, ML bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the La Serena Talca, ML bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Talca, ML bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Talca, ML on your planned travel date.

How does CheckMyBus find the best bus deals from La Serena to Talca, ML?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between La Serena and Talca, ML. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from La Serena to Talca, ML?

Prices and availability for 7 trips between La Serena and Talca, ML change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route La Serena to Talca, ML

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Talca, ML

Here’s an overview of the most popular bus routes to La Serena and to Talca, ML. Simply click on the connection of your choice, and you will find all the details about your bus route!