Bus Lakeland, FL to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Lakeland, FL to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Lakeland, FL to Florence, SC from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$102

Friday

Saturday

Sunday

$109

Monday

Tuesday

$119

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 40m	11:25 PM	Lakeland, FL	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$102	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/18/2025 11:25:00 PM to TA Travel Center, Florence, SC (USA) arriving at 12/20/2025 12:05:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 24h 40m
FlixBus	13h 55m	10:10 AM	Lakeland, FL	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$103	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/18/2025 10:10:00 AM to TA Travel Center, Florence, SC (USA) arriving at 12/19/2025 12:05:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 13h 55m
FlixBus	25h 35m	10:10 AM	Lakeland, FL	Bus Stop	11:45 AM	Florence, SC	Bus Station	Economy	$103	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/18/2025 10:10:00 AM to Bus Station, Florence, SC (USA) arriving at 12/19/2025 11:45:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 25h 35m
Greyhound US	21h 15m	4:15 PM	Lakeland, FL	Bus Stop	1:30 PM	Florence, SC	Bus Station	Economy	$105	A Bus from Greyhound US goes from Bus Stop, Lakeland, FL (USA) at 12/18/2025 4:15:00 PM to Bus Station, Florence, SC (USA) arriving at 12/19/2025 1:30:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 21h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	10:10 AM	Lakeland, FL	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$109	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/21/2025 10:10:00 AM to TA Travel Center, Florence, SC (USA) arriving at 12/22/2025 12:05:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 13h 55m
FlixBus	25h 35m	10:10 AM	Lakeland, FL	Bus Stop	11:45 AM	Florence, SC	Bus Station	Economy	$109	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/21/2025 10:10:00 AM to Bus Station, Florence, SC (USA) arriving at 12/22/2025 11:45:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 25h 35m
FlixBus	14h 10m	11:25 PM	Lakeland, FL	Bus Stop	1:35 PM	Florence, SC	Bus Station	Economy	$109	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/21/2025 11:25:00 PM to Bus Station, Florence, SC (USA) arriving at 12/22/2025 1:35:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 14h 10m
Greyhound US	21h 15m	4:15 PM	Lakeland, FL	Bus Stop	1:30 PM	Florence, SC	Bus Station	Economy	$123	A Bus from Greyhound US goes from Bus Stop, Lakeland, FL (USA) at 12/21/2025 4:15:00 PM to Bus Station, Florence, SC (USA) arriving at 12/22/2025 1:30:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 21h 15m

Did you know that if you travel from Lakeland, FL to Florence, SC via Orlando, FL, you can save more than $15? You can find the corresponding connections below.
- FlixBus
  
  14h 10m
  
  0
  
  11:25 PM
  
  Lakeland, FL
  Bus Stop
  
  12:30 AM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/18/2025 11:25:00 PM to Bus Station, Orlando, FL (USA) arriving at 12/19/2025 12:30:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 5m
- FlixBus
  
  9h 35m
  
  0
  
  4:00 AM
  
  Orlando, FL
  Bus Station
  
  1:35 PM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/19/2025 4:00:00 AM to Bus Station, Florence, SC (USA) arriving at 12/19/2025 1:35:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 9h 35m
Travel time is 0h 15m longer, but you will save $15

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	14h 10m	11:25 PM	Lakeland, FL	Bus Stop	1:35 PM	Florence, SC	Bus Station	Economy	$119	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/23/2025 11:25:00 PM to Bus Station, Florence, SC (USA) arriving at 12/24/2025 1:35:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 14h 10m
Greyhound US	21h 15m	4:15 PM	Lakeland, FL	Bus Stop	1:30 PM	Florence, SC	Bus Station	Economy	$119	A Bus from Greyhound US goes from Bus Stop, Lakeland, FL (USA) at 12/23/2025 4:15:00 PM to Bus Station, Florence, SC (USA) arriving at 12/24/2025 1:30:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 21h 15m
FlixBus	25h 35m	10:10 AM	Lakeland, FL	Bus Stop	11:45 AM	Florence, SC	Bus Station	Economy	$130	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/23/2025 10:10:00 AM to Bus Station, Florence, SC (USA) arriving at 12/24/2025 11:45:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 25h 35m
FlixBus	24h 40m	11:25 PM	Lakeland, FL	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$137	A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/23/2025 11:25:00 PM to TA Travel Center, Florence, SC (USA) arriving at 12/25/2025 12:05:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 24h 40m

Did you know that if you travel from Lakeland, FL to Florence, SC via Orlando, FL, you can save more than $25? You can find the corresponding connections below.
- FlixBus
  
  14h 10m
  
  0
  
  11:25 PM
  
  Lakeland, FL
  Bus Stop
  
  12:30 AM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Bus Stop, Lakeland, FL (USA) at 12/18/2025 11:25:00 PM to Bus Station, Orlando, FL (USA) arriving at 12/19/2025 12:30:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 5m
- FlixBus
  
  9h 35m
  
  0
  
  4:00 AM
  
  Orlando, FL
  Bus Station
  
  1:35 PM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/19/2025 4:00:00 AM to Bus Station, Florence, SC (USA) arriving at 12/19/2025 1:35:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 9h 35m
Travel time is the same as the direct connection, but you will save $25

Best Price Offer: The price for the cheapest bus from Lakeland, FL to Florence, SC is $102 on 12/18/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Lakeland, FL and Florence, SC

See here how frequent the connections between Lakeland, FL and Florence, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 5 daily buses from Lakeland, FL to Florence, SC. Sunday has instead the fewest connections, with only 5 daily coaches between Lakeland, FL and Florence, SC.

The busiest time of the day is the Morning, with 6 buses from Lakeland, FL to Florence, SC, while Afternoon sees the fewest connections between Lakeland, FL and Florence, SC, with 3 offers.

Facts about the bus from Lakeland, FL to Florence, SC

Compare all providers like FlixBus and Greyhound US that travel 5 times every day by bus from Lakeland, FL to Florence, SC in one click! Book your bus ticket from Lakeland, FL to Florence, SC starting from $102!

Cheapest Bus	$102
Fastest Bus	13h 55m
Earliest Bus	10:10 AM
Latest Bus	11:25 PM
Daily Bus Routes	5 Ø
Distance	444.7 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Lakeland, FL to Florence, SC

Every day, 5 buses from 2 bus companies leave Lakeland, FL for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$102

Friday 12/19

Saturday 12/20

Sunday 12/21

$109

Monday 12/22

Tuesday 12/23

$119

Wednesday 12/24

$122

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Lakeland, FL to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Lakeland, FL to Florence, SC, for the next 30 days.

With a price starting from $102, Thursday is the cheapest day for a bus from Lakeland, FL to Florence, SC. Tuesday instead is the most expensive day with prices starting from $119.

Evening is the cheapest day time for bus tickets from Lakeland, FL to Florence, SC, with $102. Afternoon is the most expensive time of the day with prices starting from $105.

How to save money travelling from Lakeland, FL to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lakeland, FL to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lakeland, FL to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lakeland, FL to Florence, SC are also emptier.

All bus stations and stops in Lakeland, FL and Florence, SC

In the map below, you can see where to find all bus stations in Lakeland, FL and Florence, SC.

Bus Stop

N Massachusetts Ave 303

Waffle House

Gow B Fields Park and Ride

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Service and Comfort on the bus from Lakeland, FL to Florence, SC

Want to know which seat classes are available on the buses from Lakeland, FL to Florence, SC? Or which bus companies serve the route Lakeland, FL to Florence, SC? Below you will find answers to your questions.

FAQs about the Lakeland, FL to Florence, SC bus

How much does a Lakeland, FL Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $102 and takes 24h 40m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Lakeland, FL to Florence, SC?

This route is offered by 2 companies with a range of ticket prices between $102 and $166. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Lakeland, FL to Florence, SC each day?

Every day, the Lakeland, FL to Florence, SC bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lakeland, FL to Florence, SC take?

The fastest bus from Lakeland, FL to Florence, SC is offered by FlixBus and takes 13h 55m. Bus tickets for this connection cost $103. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lakeland, FL to Florence, SC?

The earliest bus arriving in Florence, SC from Lakeland, FL starts at 10:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lakeland, FL to Florence, SC?

The latest bus trip departing from Lakeland, FL for Florence, SC starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lakeland, FL Florence, SC route?

When traveling by bus from Lakeland, FL to Florence, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lakeland, FL and Florence, SC?

You can check all the direct connections between Lakeland, FL and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Lakeland, FL to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lakeland, FL Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lakeland, FL Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lakeland, FL to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Lakeland, FL to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Lakeland, FL and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lakeland, FL to Florence, SC?

Prices and availability for 5 trips between Lakeland, FL and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lakeland, FL to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lakeland, FL and to Florence, SC

Here’s an overview of the most popular bus routes to Lakeland, FL and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!