Bus Manchester, TN to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Manchester, TN to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Manchester, TN to Florence, SC from various bus operators like Greyhound US for the next days.

today

tomorrow

$68

Wednesday

Thursday

Friday

Saturday

$68

Sunday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	13h 25m	11:05 PM	Manchester, TN	Bus Stop	1:30 PM	Florence, SC	Bus Station		Economy	$68	A Bus from Greyhound US goes from Bus Stop, Manchester, TN (USA) at 1/20/2026 11:05:00 PM to Bus Station, Florence, SC (USA) arriving at 1/21/2026 1:30:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 13h 25m
	Greyhound US	14h 40m	12:40 AM	Manchester, TN	Bus Stop	4:20 PM	Florence, SC	Bus Station		Economy	$87	A Bus from Greyhound US goes from Bus Stop, Manchester, TN (USA) at 1/20/2026 12:40:00 AM to Bus Station, Florence, SC (USA) arriving at 1/20/2026 4:20:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 25m	11:05 PM	Manchester, TN	Bus Stop	1:30 PM	Florence, SC	Bus Station	Economy	$68	A Bus from Greyhound US goes from Bus Stop, Manchester, TN (USA) at 1/24/2026 11:05:00 PM to Bus Station, Florence, SC (USA) arriving at 1/25/2026 1:30:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 13h 25m
Greyhound US	14h 40m	12:40 AM	Manchester, TN	Bus Stop	4:20 PM	Florence, SC	Bus Station	Economy	$87	A Bus from Greyhound US goes from Bus Stop, Manchester, TN (USA) at 1/24/2026 12:40:00 AM to Bus Station, Florence, SC (USA) arriving at 1/24/2026 4:20:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 40m
Greyhound US	15h 15m	7:50 AM	Manchester, TN	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$95	A Bus from Greyhound US goes from Bus Stop, Manchester, TN (USA) at 1/24/2026 7:50:00 AM to TA Travel Center, Florence, SC (USA) arriving at 1/25/2026 12:05:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 15h 15m
Greyhound US	24h 0m	11:05 PM	Manchester, TN	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$106	A Bus from Greyhound US goes from Bus Stop, Manchester, TN (USA) at 1/24/2026 11:05:00 PM to TA Travel Center, Florence, SC (USA) arriving at 1/26/2026 12:05:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 0m

Best Price Offer: The price for the cheapest bus from Manchester, TN to Florence, SC is $68 on 1/20/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Manchester, TN and Florence, SC

See here how frequent the connections between Manchester, TN and Florence, SC are, during different times and days of the week.

Saturday is the busiest day, with more than 4 daily buses from Manchester, TN to Florence, SC. Tuesday has instead the fewest connections, with only 2 daily coaches between Manchester, TN and Florence, SC.

The busiest time of the day is the Evening, with 3 buses from Manchester, TN to Florence, SC, while Morning sees the fewest connections between Manchester, TN and Florence, SC, with 1 offers.

Facts about the bus from Manchester, TN to Florence, SC

Compare all providers like Greyhound US that travel 3 times every day by bus from Manchester, TN to Florence, SC in one click! Book your bus ticket from Manchester, TN to Florence, SC starting from $68!

Cheapest Bus	$68
Fastest Bus	14h 25m
Earliest Bus	12:40 AM
Latest Bus	11:05 PM
Daily Bus Routes	3 Ø
Distance	369.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Manchester, TN to Florence, SC

Every day, 3 buses from 1 bus companies leave Manchester, TN for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

Tuesday 01/20

$68

Wednesday 01/21

Thursday 01/22

Friday 01/23

Saturday 01/24

$68

Sunday 01/25

Monday 01/26

$68

Tuesday 01/27

$68

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Manchester, TN to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Manchester, TN to Florence, SC, for the next 30 days.

With a price starting from $68, Tuesday is the cheapest day for a bus from Manchester, TN to Florence, SC. Tuesday instead is the most expensive day with prices starting from $68.

Evening is the cheapest day time for bus tickets from Manchester, TN to Florence, SC, with $68. Morning is the most expensive time of the day with prices starting from $94.

How to save money travelling from Manchester, TN to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Manchester, TN to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Manchester, TN to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Manchester, TN to Florence, SC are also emptier.

All bus stations and stops in Manchester, TN and Florence, SC

In the map below, you can see where to find all bus stations in Manchester, TN and Florence, SC.

Bus Stop

Woodbury Hwy 617

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Service and Comfort on the bus from Manchester, TN to Florence, SC

Want to know which seat classes are available on the buses from Manchester, TN to Florence, SC? Or which bus companies serve the route Manchester, TN to Florence, SC? Below you will find answers to your questions.

FAQs about the Manchester, TN to Florence, SC bus

How much does a Manchester, TN Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $68 and takes 14h 25m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Manchester, TN to Florence, SC?

This route is offered by 1 companies with a range of ticket prices between $68 and $106. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Manchester, TN to Florence, SC each day?

Every day, the Manchester, TN to Florence, SC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Manchester, TN to Florence, SC take?

The fastest bus from Manchester, TN to Florence, SC is offered by Greyhound US and takes 14h 25m. Bus tickets for this connection cost $68. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Manchester, TN to Florence, SC?

The earliest bus arriving in Florence, SC from Manchester, TN starts at 12:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Manchester, TN to Florence, SC?

The latest bus trip departing from Manchester, TN for Florence, SC starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Manchester, TN Florence, SC route?

When traveling by bus from Manchester, TN to Florence, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Manchester, TN and Florence, SC?

You can check all the direct connections between Manchester, TN and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Manchester, TN to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Manchester, TN Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Manchester, TN Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Manchester, TN to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Manchester, TN to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Manchester, TN and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Manchester, TN to Florence, SC?

Prices and availability for 3 trips between Manchester, TN and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Manchester, TN to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Manchester, TN and to Florence, SC

Here’s an overview of the most popular bus routes to Manchester, TN and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!