Which bus from Messina to Milan is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $42
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Messina to Milan

Here is a selection of the cheapest bus trips from the schedule from Messina to Milan from various bus operators like FlixBus, Itabus or Autoservizi Salemi for the next days.

today
$75
tomorrow
$48
Wednesday
$48
Thursday
$42
Friday
$79
Saturday
$57
Sunday
$57

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 20m 10:55 AM Messina Piazza della Repubblica 5:15 AM Milan San Donato Bus Station  Economy $75
FlixBus 19h 0m 10:55 AM Messina Piazza della Repubblica 5:55 AM Milan Lampugnano Bus Station  Economy $75
FlixBus 17h 25m 8:15 PM Messina Piazza della Repubblica 1:40 PM Milan Lampugnano Bus Station  Economy $84
FlixBus 18h 20m 8:15 PM Messina Piazza della Repubblica 2:35 PM Milan San Donato Bus Station  Economy $94
FlixBus 19h 40m 9:30 PM Messina Piazza della Repubblica 5:10 PM Milan Lampugnano Bus Station  Economy $100
  • Did you know that if you travel from Messina to Milan via Villa San Giovanni, you can save more than $16? You will find the corresponding connections below.
    • FlixBus
      Save more than 21%
      17h 30m
      Messina
      5 mi
      11:45 AM
      Villa San Giovanni
      Station
      5:15 AM
      Milan
      San Donato Bus Station
      0 mi
      FlixBus
      Economy
      $59
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $39? You can find the corresponding connections below.
    • FlixBus
      18h 20m
      0
      10:50 PM
      Messina
      Piazza della Repubblica
      8:10 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $25
      • Waiting Time 0h 20m
    • FlixBus
      8h 40m
      0
      8:30 AM
      Rome
      Tiburtina Bus Station
      5:10 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is 0h 55m longer, but you will save $39

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 20m 10:55 AM Messina Piazza della Repubblica 5:15 AM Milan San Donato Bus Station  Economy $48
FlixBus 19h 0m 10:55 AM Messina Piazza della Repubblica 5:55 AM Milan Lampugnano Bus Station  Economy $48
FlixBus 19h 40m 10:50 PM Messina Piazza della Repubblica 6:30 PM Milan San Donato Bus Station  Economy $91
FlixBus 19h 5m 10:50 PM Messina Piazza della Repubblica 5:55 PM Milan Lampugnano Bus Station  Economy $93
FlixBus 17h 25m 8:15 PM Messina Piazza della Repubblica 1:40 PM Milan Lampugnano Bus Station  Economy $95
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $12? You can find the corresponding connections below.
    • FlixBus
      18h 20m
      0
      10:50 PM
      Messina
      Piazza della Repubblica
      8:10 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $25
      • Waiting Time 0h 20m
    • FlixBus
      8h 40m
      0
      8:30 AM
      Rome
      Tiburtina Bus Station
      5:10 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is 0h 55m longer, but you will save $12

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 20m 10:55 AM Messina Piazza della Repubblica 5:15 AM Milan San Donato Bus Station  Economy $48
FlixBus 19h 0m 10:55 AM Messina Piazza della Repubblica 5:55 AM Milan Lampugnano Bus Station  Economy $48
FlixBus 18h 20m 8:15 PM Messina Piazza della Repubblica 2:35 PM Milan San Donato Bus Station  Economy $76
FlixBus 17h 25m 8:15 PM Messina Piazza della Repubblica 1:40 PM Milan Lampugnano Bus Station  Economy $90
FlixBus 19h 40m 10:50 PM Messina Piazza della Repubblica 6:30 PM Milan San Donato Bus Station  Economy $107
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $12? You can find the corresponding connections below.
    • FlixBus
      18h 20m
      0
      10:50 PM
      Messina
      Piazza della Repubblica
      8:10 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $25
      • Waiting Time 0h 20m
    • FlixBus
      8h 40m
      0
      8:30 AM
      Rome
      Tiburtina Bus Station
      5:10 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is 0h 55m longer, but you will save $12

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 18h 25m 9:35 PM Messina Piazza della Repubblica 4:00 PM Milan Lampugnano Bus Station  Basic $42
FlixBus 18h 20m 8:15 PM Messina Piazza della Repubblica 2:35 PM Milan San Donato Bus Station  Economy $80
FlixBus 18h 20m 10:55 AM Messina Piazza della Repubblica 5:15 AM Milan San Donato Bus Station  Economy $82
Autoservizi Salemi 15h 55m 9:15 PM Messina Piazza della Repubblica 1:10 PM Milan San Donato Bus Station  Basic $107
Autoservizi Salemi 16h 35m 9:15 PM Messina Piazza della Repubblica 1:50 PM Milan Lampugnano Bus Station  Basic $107
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $6? You can find the corresponding connections below.
    • FlixBus
      18h 20m
      0
      10:50 PM
      Messina
      Piazza della Repubblica
      8:10 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $25
      • Waiting Time 0h 20m
    • FlixBus
      8h 40m
      0
      8:30 AM
      Rome
      Tiburtina Bus Station
      5:10 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is 2h 25m longer, but you will save $6

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 40m 9:30 PM Messina Piazza della Repubblica 5:10 PM Milan Lampugnano Bus Station  Economy $79
FlixBus 18h 20m 8:15 PM Messina Piazza della Repubblica 2:35 PM Milan San Donato Bus Station  Economy $87
FlixBus 19h 40m 10:50 PM Messina Piazza della Repubblica 6:30 PM Milan San Donato Bus Station  Economy $89
FlixBus 19h 5m 10:50 PM Messina Piazza della Repubblica 5:55 PM Milan Lampugnano Bus Station  Economy $95
FlixBus 17h 25m 8:15 PM Messina Piazza della Repubblica 1:40 PM Milan Lampugnano Bus Station  Economy $104
  • Did you know that if you travel from Messina to Milan via Villa San Giovanni, you can save more than $38? You will find the corresponding connections below.
    • Save more than 48%
      17h 25m
      Messina
      5 mi
      10:35 PM
      Villa San Giovanni
      Station
      4:00 PM
      Milan
      Lampugnano Bus Station
      0 mi
      Premium Economy
      $41
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $43? You can find the corresponding connections below.
    • FlixBus
      18h 20m
      0
      10:50 PM
      Messina
      Piazza della Repubblica
      8:10 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $25
      • Waiting Time 0h 20m
    • FlixBus
      8h 40m
      0
      8:30 AM
      Rome
      Tiburtina Bus Station
      5:10 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is 0h 55m longer, but you will save $43

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 23h 59m 11:50 PM Messina Central Station 11:49 PM Milan San Donato Bus Station  Premium Economy $57
Itabus 19h 55m 11:20 PM Messina Piazza della Repubblica 7:15 PM Milan San Donato Bus Station  Basic $58
FlixBus 19h 25m 9:45 PM Messina Piazza della Repubblica 5:10 PM Milan Lampugnano Bus Station  Economy $71
FlixBus 19h 40m 10:50 PM Messina Piazza della Repubblica 6:30 PM Milan San Donato Bus Station  Economy $73
Autoservizi Salemi 15h 55m 9:15 PM Messina Piazza della Repubblica 1:10 PM Milan San Donato Bus Station  Basic $106
  • Did you know that if you travel from Messina to Milan via Villa San Giovanni, you can save more than $16? You will find the corresponding connections below.
    • Save more than 28%
      17h 25m
      Messina
      5 mi
      10:35 PM
      Villa San Giovanni
      Station
      4:00 PM
      Milan
      Lampugnano Bus Station
      0 mi
      Premium Economy
      $41
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $21? You can find the corresponding connections below.
    • FlixBus
      18h 20m
      0
      10:50 PM
      Messina
      Piazza della Repubblica
      8:10 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $25
      • Waiting Time 0h 20m
    • FlixBus
      8h 40m
      0
      8:30 AM
      Rome
      Tiburtina Bus Station
      5:10 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is 2h 25m longer, but you will save $21

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 19h 55m 11:20 PM Messina Central Station 7:15 PM Milan San Donato Bus Station  Premium Economy $57
Itabus 23h 59m 11:50 PM Messina Central Station 11:49 PM Milan San Donato Bus Station  Premium Economy $57
FlixBus 19h 40m 9:30 PM Messina Piazza della Repubblica 5:10 PM Milan Lampugnano Bus Station  Economy $88
FlixBus 18h 20m 8:15 PM Messina Piazza della Repubblica 2:35 PM Milan San Donato Bus Station  Economy $93
FlixBus 19h 40m 10:50 PM Messina Piazza della Repubblica 6:30 PM Milan San Donato Bus Station  Economy $94
  • Did you know that if you travel from Messina to Milan via Villa San Giovanni, you can save more than $16? You will find the corresponding connections below.
    • Save more than 28%
      17h 25m
      Messina
      5 mi
      10:35 PM
      Villa San Giovanni
      Station
      4:00 PM
      Milan
      Lampugnano Bus Station
      0 mi
      Premium Economy
      $41
  • Did you know that if you travel from Messina to Milan via Rome, you can save more than $21? You can find the corresponding connections below.
    • FlixBus
      18h 20m
      0
      10:50 PM
      Messina
      Piazza della Repubblica
      8:10 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $25
      • Waiting Time 0h 20m
    • FlixBus
      8h 40m
      0
      8:30 AM
      Rome
      Tiburtina Bus Station
      5:10 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is the same as the direct connection, but you will save $21

Best Price Offer: The price for the cheapest bus from Messina to Milan is $42 on 12/18/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Messina and Milan

See here how frequent the connections between Messina and Milan are, during different times and days of the week.
Saturday is the busiest day, with more than 21 daily buses from Messina to Milan. Tuesday has instead the fewest connections, with only 5 daily coaches between Messina and Milan.
The busiest time of the day is the Evening, with 51 buses from Messina to Milan, while Morning sees the fewest connections between Messina and Milan, with 14 offers.

Facts about the bus from Messina to Milan

Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 9 times every day by bus from Messina to Milan in one click! Book your bus ticket from Messina to Milan starting from $42!

Cheapest Bus $42
Fastest Bus 15h 55m
Earliest Bus 10:55 AM
Latest Bus 11:50 PM
Daily Bus Routes 9 Ø
Distance 599.7 miles
Bus Companies FlixBus, Itabus and Autoservizi Salemi

Cheapest bus connections from Messina to Milan

Every day, 9 buses from 3 bus companies leave Messina for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/15/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
$75
Tuesday 12/16
$48
Wednesday 12/17
$48
Thursday 12/18
$80
Friday 12/19
$79
Saturday 12/20
$71
Sunday 12/21
$57
Monday 12/22
$69
Tuesday 12/23
$99
Wednesday 12/24
$99
Thursday 12/25
$88
Friday 12/26
$110
Saturday 12/27
$117
Sunday 12/28
$106
Monday 12/29
$110
Tuesday 12/30
$104
Wednesday 12/31
$101
Thursday 01/01
$110
Friday 01/02
$126
Saturday 01/03
$155
Sunday 01/04
$145
Monday 01/05
$73
Tuesday 01/06
$144
Wednesday 01/07
$118
Thursday 01/08
$73
Friday 01/09
$62
Saturday 01/10

The cheapest time to travel from Messina to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Messina to Milan, for the next 30 days.
With a price starting from $42, Thursday is the cheapest day for a bus from Messina to Milan. Monday instead is the most expensive day with prices starting from $69.
Evening is the cheapest day time for bus tickets from Messina to Milan, with $42. Morning is the most expensive time of the day with prices starting from $48.

How to save money travelling from Messina to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Messina to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Messina to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Messina to Milan are also emptier.

Beloved bus companies from Messina to Milan

These are the most booked bus companies between Messina to Milan from our users.

Itabus from Messina to Milan

Itabus

Here you will find the key facts about the Itabus bus route Messina to Milan:

Cheapest Price $42
Fastest Bus 18h 25m
Earliest Bus 9:35 PM
Last Bus 11:50 PM
Daily Connections 4 Ø
Found on 12/13/2025

All bus stations and stops in Messina and Milan

In the map below, you can see where to find all bus stations in Messina and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Messina to Milan? Compare all modes of transports from Messina to Milan.

Service and Comfort on the bus from Messina to Milan

Want to know which seat classes are available on the buses from Messina to Milan? Or which bus companies serve the route Messina to Milan? Below you will find answers to your questions.

FAQs about the Messina to Milan bus

How much does a Messina Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 18h 25m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Messina to Milan?

This route is offered by 3 companies with a range of ticket prices between $42 and $134. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Messina to Milan each day?

Every day, the Messina to Milan bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Messina to Milan take?

The fastest bus from Messina to Milan is offered by Autoservizi Salemi and takes 15h 55m. Bus tickets for this connection cost $107. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Messina to Milan?

The earliest bus arriving in Milan from Messina starts at 10:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Messina to Milan?

The latest bus trip departing from Messina for Milan starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Messina Milan route?

When traveling by bus from Messina to Milan, passengers can travel with FlixBus, Itabus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Messina and Milan?

You can check all the direct connections between Messina and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Autoservizi Salemi.

What can I take with me on the Messina to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Messina Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Messina Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Messina to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Messina to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Messina and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Messina to Milan?

Prices and availability for 9 trips between Messina and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Messina to Milan

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Messina and to Milan

Here’s an overview of the most popular bus routes to Messina and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Messina from Randazzo Buses to Messina from Randazzo
Bus Taranto to Messina Bus Taranto to Messina
Caltanissetta to Messina bus Caltanissetta to Messina bus
Buses from Vibo Valentia to Messina Buses from Vibo Valentia to Messina
Bus Chamonix to Milan Bus Chamonix to Milan
Bus from Bolzano to Milan Bus from Bolzano to Milan
Buses from Ljubljana to Milan Buses from Ljubljana to Milan
Buses Frankfurt am Main - Milan Buses Frankfurt am Main - Milan
Popular Airport Shuttles to Messina and to Milan
CheckMyBus › Buses in Italy › Bus to Messina › Bus to Milan

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.