Bus Messina to Milan - Compare all Companies

Compare all timetables for the bus from Messina to Milan

Here is a selection of the cheapest bus trips from the schedule from Messina to Milan from various bus operators like Itabus, FlixBus or Autoservizi Salemi for the next days.

today

$44

tomorrow

$38

Saturday

$42

Sunday

$43

Monday

$43

Tuesday

$43

Wednesday

$47

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 30m	8:15 PM	Messina	Piazza della Repubblica	1:45 PM	Milan	Lampugnano Bus Station	Economy	$44	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/6/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/7/2026 1:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 17h 30m
FlixBus	18h 20m	10:55 AM	Messina	Piazza della Repubblica	5:15 AM	Milan	San Donato Bus Station	Economy	$54	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/6/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/7/2026 5:15:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 20m
Itabus	19h 20m	10:20 AM	Messina	Central Station	5:40 AM	Milan	Lampugnano Bus Station	Premium Economy	$69	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/6/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/7/2026 5:40:00 AM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 19h 20m
Itabus	19h 5m	9:35 PM	Messina	Central Station	4:40 PM	Milan	Lampugnano Bus Station	Premium Economy	$69	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/6/2026 9:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/7/2026 4:40:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 19h 5m
Autoservizi Salemi	15h 55m	9:15 PM	Messina	Piazza della Repubblica	1:10 PM	Milan	San Donato Bus Station	Economy	$101	A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 8/6/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/7/2026 1:10:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Messina to Milan via Rome, you can save more than $9? You can find the corresponding connections below.
- Itabus
  
  21h 15m
  
  0
  
  9:35 PM
  
  Messina
  Central Station
  
  7:45 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Itabus goes from Central Station, Messina (Italy) at 8/7/2026 9:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/8/2026 7:45:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 10h 10m
- Itabus
  
  7h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  6:50 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 8/8/2026 11:00:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 6:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 7h 50m
Travel time is 5h 20m longer, but you will save $9

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 30m	11:20 PM	Messina	Central Station	6:50 PM	Milan	San Donato Bus Station	Premium Economy	$38	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/7/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 6:50:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 30m
FlixBus	17h 30m	8:15 PM	Messina	Piazza della Repubblica	1:45 PM	Milan	Lampugnano Bus Station	Economy	$43	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/7/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/8/2026 1:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 17h 30m
FlixBus	18h 20m	10:55 AM	Messina	Piazza della Repubblica	5:15 AM	Milan	San Donato Bus Station	Economy	$54	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/7/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 5:15:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 20m
Itabus	19h 20m	10:20 AM	Messina	Central Station	5:40 AM	Milan	Lampugnano Bus Station	Premium Economy	$69	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/7/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/8/2026 5:40:00 AM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 19h 20m
Autoservizi Salemi	15h 55m	9:15 PM	Messina	Piazza della Repubblica	1:10 PM	Milan	San Donato Bus Station	Economy	$103	A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 8/7/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 1:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 15h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 30m	11:20 PM	Messina	Central Station	6:50 PM	Milan	San Donato Bus Station	Premium Economy	$42	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/8/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/9/2026 6:50:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 19h 30m
FlixBus	17h 30m	8:15 PM	Messina	Piazza della Repubblica	1:45 PM	Milan	Lampugnano Bus Station	Economy	$44	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/8/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/9/2026 1:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 17h 30m
FlixBus	18h 20m	10:55 AM	Messina	Piazza della Repubblica	5:15 AM	Milan	San Donato Bus Station	Economy	$54	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/8/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/9/2026 5:15:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 20m
Itabus	19h 20m	10:20 AM	Messina	Central Station	5:40 AM	Milan	Lampugnano Bus Station	Premium Economy	$69	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/8/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/9/2026 5:40:00 AM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 19h 20m
Autoservizi Salemi	15h 55m	9:15 PM	Messina	Piazza della Repubblica	1:10 PM	Milan	San Donato Bus Station	Economy	$100	A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 8/8/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/9/2026 1:10:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Messina to Milan via Rome, you can save more than $7? You can find the corresponding connections below.
- Itabus
  
  21h 15m
  
  0
  
  9:35 PM
  
  Messina
  Central Station
  
  7:45 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Itabus goes from Central Station, Messina (Italy) at 8/7/2026 9:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/8/2026 7:45:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 10h 10m
- Itabus
  
  7h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  6:50 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 8/8/2026 11:00:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 6:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 7h 50m
Travel time is 5h 20m longer, but you will save $7

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 30m	11:20 PM	Messina	Central Station	6:50 PM	Milan	San Donato Bus Station	Premium Economy	$43	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/9/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/10/2026 6:50:00 PM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 19h 30m
FlixBus	17h 30m	8:15 PM	Messina	Piazza della Repubblica	1:45 PM	Milan	Lampugnano Bus Station	Economy	$44	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/9/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/10/2026 1:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 17h 30m
FlixBus	18h 20m	10:55 AM	Messina	Piazza della Repubblica	5:15 AM	Milan	San Donato Bus Station	Economy	$57	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/9/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/10/2026 5:15:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 18h 20m
Itabus	19h 20m	10:20 AM	Messina	Central Station	5:40 AM	Milan	Lampugnano Bus Station	Premium Economy	$81	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/9/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/10/2026 5:40:00 AM. 50 Premium Economy ticket for $81 per person are available. Travel duration is 19h 20m
Autoservizi Salemi	15h 55m	9:15 PM	Messina	Piazza della Repubblica	1:10 PM	Milan	San Donato Bus Station	Economy	$103	A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 8/9/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/10/2026 1:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Messina to Milan via Rome, you can save more than $8? You can find the corresponding connections below.
- Itabus
  
  21h 15m
  
  0
  
  9:35 PM
  
  Messina
  Central Station
  
  7:45 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Itabus goes from Central Station, Messina (Italy) at 8/7/2026 9:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/8/2026 7:45:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 10h 10m
- Itabus
  
  7h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  6:50 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 8/8/2026 11:00:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 6:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 7h 50m
Travel time is 5h 20m longer, but you will save $8

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 30m	8:15 PM	Messina	Piazza della Repubblica	1:45 PM	Milan	Lampugnano Bus Station	Economy	$43	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/10/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/11/2026 1:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 17h 30m
Itabus	19h 30m	11:20 PM	Messina	Central Station	6:50 PM	Milan	San Donato Bus Station	Premium Economy	$48	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/10/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/11/2026 6:50:00 PM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 19h 30m
FlixBus	18h 20m	10:55 AM	Messina	Piazza della Repubblica	5:15 AM	Milan	San Donato Bus Station	Economy	$63	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/10/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/11/2026 5:15:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 18h 20m
Itabus	19h 20m	10:20 AM	Messina	Central Station	5:40 AM	Milan	Lampugnano Bus Station	Premium Economy	$81	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/10/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/11/2026 5:40:00 AM. 50 Premium Economy ticket for $81 per person are available. Travel duration is 19h 20m
Autoservizi Salemi	15h 55m	9:15 PM	Messina	Piazza della Repubblica	1:10 PM	Milan	San Donato Bus Station	Economy	$100	A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 8/10/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/11/2026 1:10:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Messina to Milan via Rome, you can save more than $8? You can find the corresponding connections below.
- Itabus
  
  21h 15m
  
  0
  
  9:35 PM
  
  Messina
  Central Station
  
  7:45 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Itabus goes from Central Station, Messina (Italy) at 8/7/2026 9:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/8/2026 7:45:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 10h 10m
- Itabus
  
  7h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  6:50 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 8/8/2026 11:00:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 6:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 7h 50m
Travel time is 5h 20m longer, but you will save $8

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 30m	11:20 PM	Messina	Central Station	6:50 PM	Milan	San Donato Bus Station	Premium Economy	$43	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/11/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/12/2026 6:50:00 PM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 19h 30m
FlixBus	17h 30m	8:15 PM	Messina	Piazza della Repubblica	1:45 PM	Milan	Lampugnano Bus Station	Economy	$58	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/11/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/12/2026 1:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 17h 30m
FlixBus	18h 20m	10:55 AM	Messina	Piazza della Repubblica	5:15 AM	Milan	San Donato Bus Station	Economy	$63	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/11/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/12/2026 5:15:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 18h 20m
Itabus	19h 20m	10:20 AM	Messina	Central Station	5:40 AM	Milan	Lampugnano Bus Station	Premium Economy	$81	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/11/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/12/2026 5:40:00 AM. 50 Premium Economy ticket for $81 per person are available. Travel duration is 19h 20m
Autoservizi Salemi	15h 55m	9:15 PM	Messina	Piazza della Repubblica	1:10 PM	Milan	San Donato Bus Station	Economy	$103	A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 8/11/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 8/12/2026 1:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Messina to Milan via Rome, you can save more than $8? You can find the corresponding connections below.
- Itabus
  
  21h 15m
  
  0
  
  9:35 PM
  
  Messina
  Central Station
  
  7:45 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Itabus goes from Central Station, Messina (Italy) at 8/7/2026 9:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/8/2026 7:45:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 10h 10m
- Itabus
  
  7h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  6:50 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 8/8/2026 11:00:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/8/2026 6:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 7h 50m
Travel time is 5h 20m longer, but you will save $8

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 30m	8:15 PM	Messina	Piazza della Repubblica	1:45 PM	Milan	Lampugnano Bus Station	Economy	$47	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/12/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/13/2026 1:45:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 17h 30m
FlixBus	19h 0m	10:55 AM	Messina	Piazza della Repubblica	5:55 AM	Milan	Lampugnano Bus Station	Economy	$60	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/12/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/13/2026 5:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 19h 0m
FlixBus	18h 20m	10:55 AM	Messina	Piazza della Repubblica	5:15 AM	Milan	San Donato Bus Station	Economy	$60	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 8/12/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 8/13/2026 5:15:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 18h 20m
Itabus	19h 20m	10:20 AM	Messina	Central Station	5:40 AM	Milan	Lampugnano Bus Station	Premium Economy	$81	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/12/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 8/13/2026 5:40:00 AM. 50 Premium Economy ticket for $81 per person are available. Travel duration is 19h 20m
Itabus	19h 5m	9:35 PM	Messina	Central Station	4:40 PM	Milan	Lampugnano Bus Station	Premium Economy	$81	A Bus from Itabus goes from Central Station, Messina (Italy) at 8/12/2026 9:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/13/2026 4:40:00 PM. 50 Premium Economy ticket for $81 per person are available. Travel duration is 19h 5m

Did you know that if you travel from Messina to Milan via Rome, you can save more than $14? You can find the corresponding connections below.
- Itabus
  
  24h 9m
  
  0
  
  11:50 PM
  
  Messina
  Central Station
  
  2:20 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $20
  
  A Bus from Itabus goes from Central Station, Messina (Italy) at 8/8/2026 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 8/9/2026 2:20:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 14h 30m
- FlixBus
  
  8h 14m
  
  0
  
  3:45 PM
  
  Rome
  Tiburtina Bus Station
  
  11:59 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 8/9/2026 3:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 8/9/2026 11:59:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 8h 14m
Travel time is 6h 39m longer, but you will save $14

Best Price Offer: The price for the cheapest bus from Messina to Milan is $36 on 8/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Messina and Milan

See here how frequent the connections between Messina and Milan are, during different times and days of the week.

Saturday is the busiest day, with more than 46 daily buses from Messina to Milan. Wednesday has instead the fewest connections, with only 22 daily coaches between Messina and Milan.

The busiest time of the day is the Morning, with 121 buses from Messina to Milan, while Afternoon sees the fewest connections between Messina and Milan, with 10 offers.

Facts about the bus from Messina to Milan

Compare all providers like Itabus, FlixBus and Autoservizi Salemi that travel 35 times every day by bus from Messina to Milan in one click! Book your bus ticket from Messina to Milan starting from $36!

Cheapest Bus	$36
Fastest Bus	15h 55m
Earliest Bus	1:30 AM
Latest Bus	9:35 PM
Daily Bus Routes	35 Ø
Distance	599.7 miles
Bus Companies	Itabus, FlixBus and Autoservizi Salemi

Cheapest bus connections from Messina to Milan

Every day, 35 buses from 3 bus companies leave Messina for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/06/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/02

Monday 08/03

Tuesday 08/04

Wednesday 08/05

Thursday 08/06

$97

Friday 08/07

$38

Saturday 08/08

$42

Sunday 08/09

$44

Monday 08/10

$43

Tuesday 08/11

$43

Wednesday 08/12

$47

Thursday 08/13

$58

Friday 08/14

$36

Saturday 08/15

$52

Sunday 08/16

$73

Monday 08/17

$92

Tuesday 08/18

$58

Wednesday 08/19

$72

Thursday 08/20

$63

Friday 08/21

$76

Saturday 08/22

$72

Sunday 08/23

$81

Monday 08/24

$74

Tuesday 08/25

$76

Wednesday 08/26

$76

Thursday 08/27

$76

Friday 08/28

$47

Saturday 08/29

The cheapest time to travel from Messina to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Messina to Milan, for the next 30 days.

With a price starting from $36, Friday is the cheapest day for a bus from Messina to Milan. Wednesday instead is the most expensive day with prices starting from $47.

Night is the cheapest day time for bus tickets from Messina to Milan, with $36. Afternoon is the most expensive time of the day with prices starting from $108.

How to save money travelling from Messina to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Messina to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Messina to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Messina to Milan are also emptier.

All bus stations and stops in Messina and Milan

In the map below, you can see where to find all bus stations in Messina and Milan.

Piazza della Repubblica

Piazza della Repubblica 25

Via Taormina - Policlinico Bus Stop

Viale Gazzi Bus Stop

SS114 Orientale Sicula Bus Stop

SS114 Bus Stop

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Bus Station

Duomo Bus Stop

Piazza del Duomo

Service and Comfort on the bus from Messina to Milan

Want to know which seat classes are available on the buses from Messina to Milan? Or which bus companies serve the route Messina to Milan? Below you will find answers to your questions.

FAQs about the Messina to Milan bus

How much does a Messina Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $36 and takes 19h 30m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Messina to Milan?

This route is offered by 3 companies with a range of ticket prices between $36 and $175. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Messina to Milan each day?

Every day, the Messina to Milan bus route is served by approximately 35 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Messina to Milan take?

The fastest bus from Messina to Milan is offered by Autoservizi Salemi and takes 15h 55m. Bus tickets for this connection cost $101. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Messina to Milan?

The earliest bus arriving in Milan from Messina starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Messina to Milan?

The latest bus trip departing from Messina for Milan starts at 9:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Messina Milan route?

When traveling by bus from Messina to Milan, passengers can travel with Itabus, FlixBus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Messina and Milan?

You can check all the direct connections between Messina and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, FlixBus and Autoservizi Salemi.

What can I take with me on the Messina to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Messina Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Messina Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Messina to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Messina to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 35 daily trips between Messina and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Messina to Milan?

Prices and availability for 35 trips between Messina and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Messina to Milan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Messina and to Milan

Here’s an overview of the most popular bus routes to Messina and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!