Bus Midland, TX to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Midland, TX to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Midland, TX to Knoxville, TN from various bus operators like Greyhound US for the next days.

today

$109

tomorrow

Wednesday

$117

Thursday

$143

Friday

$141

Saturday

$144

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 50m	11:00 AM	Midland, TX	Younger Rd Bus Stop	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$109	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/20/2026 11:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/21/2026 9:50:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 33h 50m
Greyhound US	25h 20m	8:20 PM	Midland, TX	Younger Rd Bus Stop	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$110	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/20/2026 8:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/21/2026 10:40:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 25h 20m
Greyhound US	42h 10m	12:20 AM	Midland, TX	Younger Rd Bus Stop	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$118	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/20/2026 12:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/21/2026 7:30:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 42h 10m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 20m	8:20 PM	Midland, TX	Younger Rd Bus Stop	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$117	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/22/2026 8:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/23/2026 10:40:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 25h 20m
Greyhound US	33h 50m	11:00 AM	Midland, TX	Younger Rd Bus Stop	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$118	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/22/2026 11:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/23/2026 9:50:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 33h 50m
Greyhound US	42h 10m	12:20 AM	Midland, TX	Younger Rd Bus Stop	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$127	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/22/2026 12:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/23/2026 7:30:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 42h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 20m	8:20 PM	Midland, TX	Younger Rd Bus Stop	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$143	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/23/2026 8:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/24/2026 10:40:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 25h 20m
Greyhound US	33h 50m	11:00 AM	Midland, TX	Younger Rd Bus Stop	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$144	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/23/2026 11:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/24/2026 9:50:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 33h 50m
Greyhound US	42h 10m	12:20 AM	Midland, TX	Younger Rd Bus Stop	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$147	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/23/2026 12:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/24/2026 7:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 42h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 50m	11:00 AM	Midland, TX	Younger Rd Bus Stop	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$141	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/24/2026 11:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/25/2026 9:50:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 33h 50m
Greyhound US	25h 20m	8:20 PM	Midland, TX	Younger Rd Bus Stop	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$141	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/24/2026 8:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/25/2026 10:40:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 25h 20m
Greyhound US	42h 10m	12:20 AM	Midland, TX	Younger Rd Bus Stop	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$150	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/24/2026 12:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/25/2026 7:30:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 42h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 50m	11:00 AM	Midland, TX	Younger Rd Bus Stop	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$144	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/25/2026 11:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/26/2026 9:50:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 33h 50m
Greyhound US	25h 20m	8:20 PM	Midland, TX	Younger Rd Bus Stop	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$146	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/25/2026 8:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/26/2026 10:40:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 25h 20m
Greyhound US	42h 10m	12:20 AM	Midland, TX	Younger Rd Bus Stop	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$148	A Bus from Greyhound US goes from Younger Rd Bus Stop, Midland, TX (USA) at 4/25/2026 12:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/26/2026 7:30:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 42h 10m

Best Price Offer: The price for the cheapest bus from Midland, TX to Knoxville, TN is $109 on 4/20/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Midland, TX and Knoxville, TN

See here how frequent the connections between Midland, TX and Knoxville, TN are, during different times and days of the week.

Monday is the busiest day, with more than 3 daily buses from Midland, TX to Knoxville, TN. Monday has instead the fewest connections, with only 3 daily coaches between Midland, TX and Knoxville, TN.

The busiest time of the day is the Morning, with 5 buses from Midland, TX to Knoxville, TN, while Morning sees the fewest connections between Midland, TX and Knoxville, TN, with 5 offers.

Facts about the bus from Midland, TX to Knoxville, TN

Compare all providers like Greyhound US that travel 3 times every day by bus from Midland, TX to Knoxville, TN in one click! Book your bus ticket from Midland, TX to Knoxville, TN starting from $109!

Cheapest Bus	$109
Fastest Bus	26h 20m
Earliest Bus	12:20 AM
Latest Bus	8:20 PM
Daily Bus Routes	3 Ø
Distance	1,074.7 miles
Bus Companies	Greyhound US

Cheapest bus connections from Midland, TX to Knoxville, TN

Every day, 3 buses from 1 bus companies leave Midland, TX for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$109

Tuesday 04/21

Wednesday 04/22

$117

Thursday 04/23

$143

Friday 04/24

$141

Saturday 04/25

$144

Sunday 04/26

Monday 04/27

$134

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

Friday 05/01

Saturday 05/02

$139

Sunday 05/03

$143

Monday 05/04

$146

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$142

Saturday 05/09

$138

Sunday 05/10

Monday 05/11

$123

Tuesday 05/12

Wednesday 05/13

$139

Thursday 05/14

Friday 05/15

Saturday 05/16

The cheapest time to travel from Midland, TX to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Midland, TX to Knoxville, TN, for the next 30 days.

With a price starting from $109, Monday is the cheapest day for a bus from Midland, TX to Knoxville, TN. Thursday instead is the most expensive day with prices starting from $143.

Morning is the cheapest day time for bus tickets from Midland, TX to Knoxville, TN, with $109. Evening is the most expensive time of the day with prices starting from $110.

How to save money travelling from Midland, TX to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Midland, TX to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Midland, TX to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Midland, TX to Knoxville, TN are also emptier.

All bus stations and stops in Midland, TX and Knoxville, TN

In the map below, you can see where to find all bus stations in Midland, TX and Knoxville, TN.

Younger Rd Bus Stop

10399-9901 Pilot Ave

Main & Washington Bus Stop

Rankin Hwy

Rankin & Wolcott

Valero Gas Station

Kingston Pike

Kingston Pike 6927

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Transit Center

E Church Ave 301

Service and Comfort on the bus from Midland, TX to Knoxville, TN

Want to know which seat classes are available on the buses from Midland, TX to Knoxville, TN? Or which bus companies serve the route Midland, TX to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Midland, TX to Knoxville, TN bus

How much does a Midland, TX Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $109 and takes 34h 50m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Midland, TX to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $109 and $150. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Midland, TX to Knoxville, TN each day?

Every day, the Midland, TX to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Midland, TX to Knoxville, TN take?

The fastest bus from Midland, TX to Knoxville, TN is offered by Greyhound US and takes 26h 20m. Bus tickets for this connection cost $110. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Midland, TX to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Midland, TX starts at 12:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Midland, TX to Knoxville, TN?

The latest bus trip departing from Midland, TX for Knoxville, TN starts at 8:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Midland, TX Knoxville, TN route?

When traveling by bus from Midland, TX to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Midland, TX and Knoxville, TN?

You can check all the direct connections between Midland, TX and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Midland, TX to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Midland, TX Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Midland, TX Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Midland, TX to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Midland, TX to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Midland, TX and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Midland, TX to Knoxville, TN?

Prices and availability for 3 trips between Midland, TX and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Midland, TX to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Midland, TX and to Knoxville, TN

Here’s an overview of the most popular bus routes to Midland, TX and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!