Compare all timetables for the bus from Milan to Messina
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 50m | 12:30 PM | Milan | San Donato Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $48 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/4/2026 12:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/5/2026 6:20:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 17h 50m
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| FlixBus | 21h 50m | 10:00 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $50 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/4/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/5/2026 7:50:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 21h 50m
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| FlixBus | 17h 15m | 1:05 PM | Milan | Lampugnano Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $54 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/4/2026 1:05:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/5/2026 6:20:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 17h 15m
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Distribusion19h 5m010:40 AMMilanLampugnano Bus Station7:15 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 10:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/6/2026 7:15:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 8h 35m
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Bookaway10h 15m07:30 PMRomeTiburtina Bus Station5:45 AMMessinaPiazza della Repubblica0BasicA Bus from Bookaway goes from Tiburtina Bus Station, Rome (Italy) at 2/6/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 5:45:00 AM. 50 Basic ticket for $26 per person are available. Travel duration is 10h 15m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 21h 10m | 8:35 PM | Milan | Lampugnano Bus Station | 5:45 PM | Messina | Piazza della Repubblica | Economy | $58 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/5/2026 8:35:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/6/2026 5:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 21h 10m
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| FlixBus | 20h 25m | 9:20 PM | Milan | San Donato Bus Station | 5:45 PM | Messina | Piazza della Repubblica | Economy | $58 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/5/2026 9:20:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/6/2026 5:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 20h 25m
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| FlixBus | 17h 45m | 12:30 PM | Milan | Lampugnano Bus Station | 6:15 AM | Messina | Piazza della Repubblica | Economy | $63 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/5/2026 12:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/6/2026 6:15:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 45m
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| Itabus | 20h 0m | 9:45 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $77 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/5/2026 9:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/6/2026 5:45:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 20h 0m
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Distribusion19h 5m010:40 AMMilanLampugnano Bus Station7:15 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 10:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/6/2026 7:15:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 8h 35m
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Bookaway10h 15m07:30 PMRomeTiburtina Bus Station5:45 AMMessinaPiazza della Repubblica0BasicA Bus from Bookaway goes from Tiburtina Bus Station, Rome (Italy) at 2/6/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 5:45:00 AM. 50 Basic ticket for $26 per person are available. Travel duration is 10h 15m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 18h 40m | 3:30 PM | Milan | Lampugnano Bus Station | 10:10 AM | Messina | Piazza della Repubblica | Economy | $45 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 3:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 10:10:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 18h 40m
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| FlixBus | 20h 40m | 9:40 AM | Milan | San Donato Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $46 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/6/2026 9:40:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 6:20:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 20h 40m
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| FlixBus | 19h 25m | 2:45 PM | Milan | San Donato Bus Station | 10:10 AM | Messina | Piazza della Repubblica | Economy | $48 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/6/2026 2:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 10:10:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 19h 25m
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| Itabus | 20h 0m | 9:45 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $83 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 9:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 5:45:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 20h 0m
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FlixBus18h 20mMilan5 mi3:50 PMAssagoMilanofiori Forum10:10 AMMessinaPiazza della Repubblica0 miEconomyA Bus from FlixBus goes from Milanofiori Forum, Assago (Italy) at 2/6/2026 3:50:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 10:10:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 18h 20m
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Distribusion19h 5m010:40 AMMilanLampugnano Bus Station7:15 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 10:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/6/2026 7:15:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 8h 35m
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Bookaway10h 15m07:30 PMRomeTiburtina Bus Station5:45 AMMessinaPiazza della Repubblica0BasicA Bus from Bookaway goes from Tiburtina Bus Station, Rome (Italy) at 2/6/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/7/2026 5:45:00 AM. 50 Basic ticket for $26 per person are available. Travel duration is 10h 15m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 50m | 12:30 PM | Milan | San Donato Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/7/2026 12:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/8/2026 6:20:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 17h 50m
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| FlixBus | 20h 30m | 11:20 PM | Milan | San Donato Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/7/2026 11:20:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/8/2026 7:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 20h 30m
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| FlixBus | 21h 5m | 10:45 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $33 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/7/2026 10:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/8/2026 7:50:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 21h 5m
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| Itabus | 20h 0m | 9:45 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $77 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/7/2026 9:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/8/2026 5:45:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 20h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 21h 5m | 10:45 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $34 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/8/2026 10:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/9/2026 7:50:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 21h 5m
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| FlixBus | 20h 30m | 11:20 PM | Milan | San Donato Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $34 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/8/2026 11:20:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/9/2026 7:50:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 20h 30m
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| FlixBus | 17h 50m | 12:30 PM | Milan | San Donato Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $35 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/8/2026 12:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/9/2026 6:20:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 17h 50m
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| Itabus | 20h 0m | 9:45 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $117 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/8/2026 9:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/9/2026 5:45:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 20h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 18h 50m | 3:30 PM | Milan | Lampugnano Bus Station | 10:20 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 3:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/10/2026 10:20:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 18h 50m
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| FlixBus | 21h 5m | 10:45 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 10:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/10/2026 7:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 21h 5m
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| FlixBus | 19h 35m | 2:45 PM | Milan | San Donato Bus Station | 10:20 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/9/2026 2:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/10/2026 10:20:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 19h 35m
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| Itabus | 19h 5m | 10:40 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $74 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 10:40:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/10/2026 5:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 19h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 18h 50m | 3:30 PM | Milan | Lampugnano Bus Station | 10:20 AM | Messina | Piazza della Repubblica | Economy | $34 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/10/2026 3:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/11/2026 10:20:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 18h 50m
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| FlixBus | 21h 50m | 10:00 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $34 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/10/2026 10:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/11/2026 7:50:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 21h 50m
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| FlixBus | 22h 30m | 9:20 PM | Milan | San Donato Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $35 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/10/2026 9:20:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 2/11/2026 7:50:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 22h 30m
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| Itabus | 20h 0m | 9:45 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $63 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/10/2026 9:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/11/2026 5:45:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 20h 0m
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Distribusion27h 40m04:00 PMMilanLampugnano Bus Station11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 4:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/9/2026 11:45:00 PM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 7h 45m
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FlixBus10h 55m08:45 AMRomeTiburtina Bus Station7:40 PMMessinaPiazza della Repubblica0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 2/10/2026 8:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 2/10/2026 7:40:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 10h 55m
Waiting Time 9h 0m -
Best Price Offer: The price for the cheapest bus from Milan to Messina is $25 on 2/21/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Milan and Messina
Facts about the bus from Milan to Messina
Compare all providers like FlixBus and Itabus that travel 10 times every day by bus from Milan to Messina in one click! Book your bus ticket from Milan to Messina starting from $25!
| Cheapest Bus | $25 |
| Fastest Bus | 17h 15m |
| Earliest Bus | 12:30 PM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 10 Ø |
| Distance | 599.7 miles |
| Bus Companies | FlixBus and Itabus |
Cheapest bus connections from Milan to Messina
Every day, 10 buses from 2 bus companies leave Milan for Messina: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/04/2026 and for the following days.
The cheapest time to travel from Milan to Messina
How to save money travelling from Milan to Messina
Book the ticket from Milan to Messina in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Messina, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Messina are also emptier.All bus stations and stops in Milan and Messina
In the map below, you can see where to find all bus stations in Milan and Messina.
Compare the bus with other modes of transport
Service and Comfort on the bus from Milan to Messina
FAQs about the Milan to Messina bus
How much does a Milan Messina bus trip cost?
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On average, how many connections are available from Milan to Messina each day?
How long does a bus journey from Milan to Messina take?
What time is the first bus from Milan to Messina?
What time is the last bus from Milan to Messina?
Which bus companies operate the Milan Messina route?
Is there a direct bus between Milan and Messina?
What can I take with me on the Milan to Messina bus route?
What equipment is available for the Milan Messina bus route?
How does CheckMyBus find the best bus deals from Milan to Messina?
How does CheckMyBus technology work for trips from Milan to Messina?
Available seat classes which are offered on the bus route Milan to Messina
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Milan and to Messina
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