Bus Palermo to Brindisi: Compare prices and save money

Compare all timetables for the bus from Palermo to Brindisi

Here is a selection of the cheapest bus trips from the schedule from Palermo to Brindisi from various bus operators like FlixBus for the next days.

today

tomorrow

$49

Friday

$62

Saturday

Sunday

$62

Monday

Tuesday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 20m	9:10 PM	Palermo	Via Tommaso Fazello Bus Stop	4:30 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop		Economy	$49	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 6/25/2026 9:10:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 6/26/2026 4:30:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 19h 20m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	11h 45m	6:15 PM	Palermo	Via Tommaso Fazello Bus Stop	6:00 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop		Economy	$62	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 6/26/2026 6:15:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 6/27/2026 6:00:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 45m

Did you know that if you travel from Palermo to Brindisi via Lamezia Terme, you can save more than $8? You can find the corresponding connections below.
- FlixBus
  
  14h 35m
  
  0
  
  3:25 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  1:10 AM
  
  Lamezia Terme
  Central Station
  
  0
  
  Economy
  
  $31
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 6/26/2026 3:25:00 PM to Central Station, Lamezia Terme (Italy) arriving at 6/27/2026 1:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 9h 45m
- FlixBus
  
  4h 45m
  
  0
  
  1:15 AM
  
  Lamezia Terme
  Central Station
  
  6:00 AM
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Economy
  
  $23
  
  A Bus from FlixBus goes from Central Station, Lamezia Terme (Italy) at 6/27/2026 1:15:00 AM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 6/27/2026 6:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 4h 45m
Travel time is 2h 50m longer, but you will save $8

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	11h 45m	6:15 PM	Palermo	Via Tommaso Fazello Bus Stop	6:00 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop		Economy	$62	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 6/28/2026 6:15:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 6/29/2026 6:00:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 45m

Did you know that if you travel from Palermo to Brindisi via Lamezia Terme, you can save more than $8? You can find the corresponding connections below.
- FlixBus
  
  14h 35m
  
  0
  
  3:25 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  1:10 AM
  
  Lamezia Terme
  Central Station
  
  0
  
  Economy
  
  $31
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 6/26/2026 3:25:00 PM to Central Station, Lamezia Terme (Italy) arriving at 6/27/2026 1:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 9h 45m
- FlixBus
  
  4h 45m
  
  0
  
  1:15 AM
  
  Lamezia Terme
  Central Station
  
  6:00 AM
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Economy
  
  $23
  
  A Bus from FlixBus goes from Central Station, Lamezia Terme (Italy) at 6/27/2026 1:15:00 AM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 6/27/2026 6:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 4h 45m
Travel time is 2h 50m longer, but you will save $8

Best Price Offer: The price for the cheapest bus from Palermo to Brindisi is $48 on 7/11/2026. Flexible travelers save on ticket prices.

Facts about the bus from Palermo to Brindisi

Compare all providers like FlixBus that travel 1 times every day by bus from Palermo to Brindisi in one click! Book your bus ticket from Palermo to Brindisi starting from $48!

Cheapest Bus	$48
Fastest Bus	11h 45m
Earliest Bus	9:10 PM
Latest Bus	6:15 PM
Daily Bus Routes	1 Ø
Distance	300.2 miles
Bus Companies	FlixBus

Cheapest bus connections from Palermo to Brindisi

Every day, 1 buses from 1 bus companies leave Palermo for Brindisi: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

Tuesday 06/23

Wednesday 06/24

Thursday 06/25

$49

Friday 06/26

$62

Saturday 06/27

Sunday 06/28

$62

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

Saturday 07/11

$48

Sunday 07/12

Monday 07/13

$62

Tuesday 07/14

Wednesday 07/15

Thursday 07/16

Friday 07/17

$70

Saturday 07/18

How to save money travelling from Palermo to Brindisi

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Brindisi in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Brindisi, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Palermo to Brindisi are also emptier.

All bus stations and stops in Palermo and Brindisi

In the map below, you can see where to find all bus stations in Palermo and Brindisi.

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Via Giuseppe Maria Galanti Bus Stop

Via Giuseppe Maria Galanti 8

Port

Ospedale "A. Perrino" Bus Stop

Costa Morena Bus Stop

Viale Arno Bus Stop

Viale Arno

Service and Comfort on the bus from Palermo to Brindisi

Want to know which seat classes are available on the buses from Palermo to Brindisi? Or which bus companies serve the route Palermo to Brindisi? Below you will find answers to your questions.

FAQs about the Palermo to Brindisi bus

How much does a Palermo Brindisi bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $48 and takes 19h 20m to reach Brindisi. Compare offers to save money!

How much could I save by comparing buses from Palermo to Brindisi?

This route is offered by 1 companies with a range of ticket prices between $48 and $62. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brindisi.

On average, how many connections are available from Palermo to Brindisi each day?

Every day, the Palermo to Brindisi bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Palermo to Brindisi take?

The fastest bus from Palermo to Brindisi is offered by FlixBus and takes 11h 45m. Bus tickets for this connection cost $62. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Palermo to Brindisi?

The earliest bus arriving in Brindisi from Palermo starts at 9:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Palermo to Brindisi?

The latest bus trip departing from Palermo for Brindisi starts at 6:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Palermo Brindisi route?

When traveling by bus from Palermo to Brindisi, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Palermo and Brindisi?

You can check all the direct connections between Palermo and Brindisi by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Palermo to Brindisi bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Palermo Brindisi bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Brindisi bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Brindisi on your planned travel date.

How does CheckMyBus find the best bus deals from Palermo to Brindisi?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Palermo and Brindisi. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Palermo to Brindisi?

Prices and availability for 1 trips between Palermo and Brindisi change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Palermo to Brindisi

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Brindisi

Here’s an overview of the most popular bus routes to Palermo and to Brindisi. Simply click on the connection of your choice, and you will find all the details about your bus route!