Bus Santa Maria, RS to São Paulo - Compare all Companies

Stopover connections from Santa Maria, RS and São Paulo

There are unfortunately no direct trips between Santa Maria, RS and São Paulo at this moment. However, we found these stopover connections between the two cities. Check the offers below!

CHEAP 24:25

Santa Maria, RS

616 km - 16:45

Joinville, SC

379 km - 9:40

São Paulo

Santa Maria, RS

Joinville, SC

from $51

from $46

from $52

Joinville, SC

São Paulo

from $18

from $12

from $26

Other companies are 1001, Viação Penha, Viação Eucatur and 3 more.

FAST 23:55

Santa Maria, RS

210 km - 5:25

Passo Fundo, RS

779 km - 18:30

São Paulo

Santa Maria, RS

Passo Fundo, RS

from $18

from $27

Passo Fundo, RS

São Paulo

from $70

from $68

Cheapest bus connections from Santa Maria, RS to São Paulo

Every day, buses from bus companies leave Santa Maria, RS for São Paulo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

$87

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

How to save money travelling from Santa Maria, RS to São Paulo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Maria, RS to São Paulo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Maria, RS to São Paulo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Maria, RS to São Paulo are also emptier.

All bus stations and stops in Santa Maria, RS and São Paulo

In the map below, you can see where to find all bus stations in Santa Maria, RS and São Paulo.

Bus Station

Rua Pedro Pereira 1450

Camobi

Tietê Bus Station

Vila Guilherme

Barra Funda Bus Station

Rua Aloysio Biondi, s/n Barra Funda

Sala VIP Bella Vita

Av. Ordem e Progresso 95

Jabaquara Bus Station

Avenida Engenheiro Armando de Arruda Pereira 2022

Shopping Feira da Madrugada Bus Stop

Rua São Caetano 812

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santa Maria, RS to São Paulo? Compare all modes of transports from Santa Maria, RS to São Paulo.

Service and Comfort on the bus from Santa Maria, RS to São Paulo

Want to know which seat classes are available on the buses from Santa Maria, RS to São Paulo? Or which bus companies serve the route Santa Maria, RS to São Paulo? Below you will find answers to your questions.

FAQs about the Santa Maria, RS to São Paulo bus

How much does a Santa Maria, RS São Paulo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from and takes to reach São Paulo. Compare offers to save money!

How much could I save by comparing buses from Santa Maria, RS to São Paulo?

This route is offered by companies with a range of ticket prices between and . Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to São Paulo.

On average, how many connections are available from Santa Maria, RS to São Paulo each day?

Every day, the Santa Maria, RS to São Paulo bus route is served by approximately connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Maria, RS to São Paulo take?

The fastest bus from Santa Maria, RS to São Paulo is offered by and takes . Bus tickets for this connection cost . In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Maria, RS to São Paulo?

The earliest bus arriving in São Paulo from Santa Maria, RS starts at . However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Maria, RS to São Paulo?

The latest bus trip departing from Santa Maria, RS for São Paulo starts at . Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Maria, RS São Paulo route?

When traveling by bus from Santa Maria, RS to São Paulo, passengers can travel with . With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Maria, RS and São Paulo?

You can check all the direct connections between Santa Maria, RS and São Paulo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: .

What can I take with me on the Santa Maria, RS to São Paulo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Maria, RS São Paulo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Maria, RS São Paulo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Maria, RS to São Paulo on your planned travel date.

How does CheckMyBus find the best bus deals from Santa Maria, RS to São Paulo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for daily trips between Santa Maria, RS and São Paulo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santa Maria, RS to São Paulo?

Prices and availability for trips between Santa Maria, RS and São Paulo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

More bus routes to Santa Maria, RS and to São Paulo

Here’s an overview of the most popular bus routes to Santa Maria, RS and to São Paulo. Simply click on the connection of your choice, and you will find all the details about your bus route!