Bus St. Louis, MO to Tuscaloosa, AL - Compare all Companies

Compare all timetables for the bus from St. Louis, MO to Tuscaloosa, AL

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Tuscaloosa, AL from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$79

Wednesday

Thursday

$83

Friday

$86

Saturday

$76

Sunday

$82

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	1:00 AM	St. Louis, MO	Gateway Station	5:30 PM	Tuscaloosa, AL	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/21/2026 1:00:00 AM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/21/2026 5:30:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 16h 30m
Greyhound US	25h 35m	2:00 AM	St. Louis, MO	Gateway Station	3:35 AM	Tuscaloosa, AL	Greyhound Bus Station	Economy	$80	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/21/2026 2:00:00 AM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/22/2026 3:35:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 25h 35m
Greyhound US	19h 15m	1:45 PM	St. Louis, MO	Gateway Station	9:00 AM	Tuscaloosa, AL	Greyhound Bus Station	Economy	$81	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/21/2026 1:45:00 PM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/22/2026 9:00:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 19h 15m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	16h 30m	1:00 AM	St. Louis, MO	Gateway Station	5:30 PM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$83	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 1:00:00 AM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/23/2026 5:30:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 16h 30m
	FlixBus	11h 35m	4:00 PM	St. Louis, MO	Gateway Station	3:35 AM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$84	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 4:00:00 PM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/24/2026 3:35:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 11h 35m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	11h 35m	4:00 PM	St. Louis, MO	Gateway Station	3:35 AM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$86	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 4:00:00 PM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/25/2026 3:35:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 11h 35m
	Greyhound US	16h 30m	1:00 AM	St. Louis, MO	Gateway Station	5:30 PM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$87	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 1:00:00 AM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/24/2026 5:30:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 16h 30m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	16h 30m	1:00 AM	St. Louis, MO	Gateway Station	5:30 PM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$76	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 1:00:00 AM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/25/2026 5:30:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 16h 30m
	FlixBus	11h 35m	4:00 PM	St. Louis, MO	Gateway Station	3:35 AM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$77	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 4:00:00 PM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/26/2026 3:35:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 11h 35m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	16h 30m	1:00 AM	St. Louis, MO	Gateway Station	5:30 PM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$82	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 1:00:00 AM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/26/2026 5:30:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 16h 30m
	FlixBus	11h 35m	4:00 PM	St. Louis, MO	Gateway Station	3:35 AM	Tuscaloosa, AL	Greyhound Bus Station		Economy	$83	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 4:00:00 PM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/27/2026 3:35:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 11h 35m

Did you know that if you travel from St. Louis, MO to Tuscaloosa, AL via Birmingham, AL, you can save more than $9? You can find the corresponding connections below.
- FlixBus
  
  11h 35m
  
  0
  
  4:00 PM
  
  St. Louis, MO
  Gateway Station
  
  1:55 AM
  
  Birmingham, AL
  MAX Central Station
  
  0
  
  Economy
  
  $63
  
  A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/27/2026 4:00:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 4/28/2026 1:55:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 9h 55m
- Greyhound US
  
  1h 10m
  
  0
  
  2:25 AM
  
  Birmingham, AL
  MAX Central Station
  
  3:35 AM
  
  Tuscaloosa, AL
  Greyhound Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from Greyhound US goes from MAX Central Station, Birmingham, AL (USA) at 4/28/2026 2:25:00 AM to Greyhound Bus Station, Tuscaloosa, AL (USA) arriving at 4/28/2026 3:35:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 10m
Travel time is the same as the direct connection, but you will save $9

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Tuscaloosa, AL is $72 on 4/30/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Tuscaloosa, AL

See here how frequent the connections between St. Louis, MO and Tuscaloosa, AL are, during different times and days of the week.

Tuesday is the busiest day, with more than 6 daily buses from St. Louis, MO to Tuscaloosa, AL. Sunday has instead the fewest connections, with only 2 daily coaches between St. Louis, MO and Tuscaloosa, AL.

The busiest time of the day is the Night, with 9 buses from St. Louis, MO to Tuscaloosa, AL, while Afternoon sees the fewest connections between St. Louis, MO and Tuscaloosa, AL, with 7 offers.

Facts about the bus from St. Louis, MO to Tuscaloosa, AL

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from St. Louis, MO to Tuscaloosa, AL in one click! Book your bus ticket from St. Louis, MO to Tuscaloosa, AL starting from $72!

Cheapest Bus	$72
Fastest Bus	11h 35m
Earliest Bus	1:00 AM
Latest Bus	4:00 PM
Daily Bus Routes	3 Ø
Distance	403.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Tuscaloosa, AL

Every day, 3 buses from 2 bus companies leave St. Louis, MO for Tuscaloosa, AL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

Tuesday 04/21

$83

Wednesday 04/22

Thursday 04/23

$83

Friday 04/24

$86

Saturday 04/25

$80

Sunday 04/26

$82

Monday 04/27

Tuesday 04/28

Wednesday 04/29

$78

Thursday 04/30

$72

Friday 05/01

$75

Saturday 05/02

$82

Sunday 05/03

$74

Monday 05/04

$76

Tuesday 05/05

$88

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

$86

Sunday 05/10

$85

Monday 05/11

$79

Tuesday 05/12

$85

Wednesday 05/13

$89

Thursday 05/14

$82

Friday 05/15

$85

Saturday 05/16

The cheapest time to travel from St. Louis, MO to Tuscaloosa, AL

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Tuscaloosa, AL, for the next 30 days.

With a price starting from $72, Thursday is the cheapest day for a bus from St. Louis, MO to Tuscaloosa, AL. Tuesday instead is the most expensive day with prices starting from $79.

Night is the cheapest day time for bus tickets from St. Louis, MO to Tuscaloosa, AL, with $72. Afternoon is the most expensive time of the day with prices starting from $77.

How to save money travelling from St. Louis, MO to Tuscaloosa, AL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Tuscaloosa, AL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Tuscaloosa, AL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Tuscaloosa, AL are also emptier.

All bus stations and stops in St. Louis, MO and Tuscaloosa, AL

In the map below, you can see where to find all bus stations in St. Louis, MO and Tuscaloosa, AL.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Bus Stop

Hwy 82 E 7022

I-20/Exit 73

McFarland Blvd E 4711

Embassy Suites by Hilton Tuscaloosa Alabama Dowtown

Greyhound Bus Station

Greensboro Ave

TA Gas Station

Buttermilk Rd

Service and Comfort on the bus from St. Louis, MO to Tuscaloosa, AL

Want to know which seat classes are available on the buses from St. Louis, MO to Tuscaloosa, AL? Or which bus companies serve the route St. Louis, MO to Tuscaloosa, AL? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Tuscaloosa, AL bus

How much does a St. Louis, MO Tuscaloosa, AL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $72 and takes 16h 30m to reach Tuscaloosa, AL. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Tuscaloosa, AL?

This route is offered by 2 companies with a range of ticket prices between $72 and $87. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Tuscaloosa, AL.

On average, how many connections are available from St. Louis, MO to Tuscaloosa, AL each day?

Every day, the St. Louis, MO to Tuscaloosa, AL bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Tuscaloosa, AL take?

The fastest bus from St. Louis, MO to Tuscaloosa, AL is offered by FlixBus and takes 11h 35m. Bus tickets for this connection cost $84. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Tuscaloosa, AL?

The earliest bus arriving in Tuscaloosa, AL from St. Louis, MO starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Tuscaloosa, AL?

The latest bus trip departing from St. Louis, MO for Tuscaloosa, AL starts at 4:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Tuscaloosa, AL route?

When traveling by bus from St. Louis, MO to Tuscaloosa, AL, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Tuscaloosa, AL?

You can check all the direct connections between St. Louis, MO and Tuscaloosa, AL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Tuscaloosa, AL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Tuscaloosa, AL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Tuscaloosa, AL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Tuscaloosa, AL on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Tuscaloosa, AL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between St. Louis, MO and Tuscaloosa, AL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Tuscaloosa, AL?

Prices and availability for 3 trips between St. Louis, MO and Tuscaloosa, AL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Tuscaloosa, AL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Tuscaloosa, AL

Here’s an overview of the most popular bus routes to St. Louis, MO and to Tuscaloosa, AL. Simply click on the connection of your choice, and you will find all the details about your bus route!