Bus from Talca, ML to La Serena from $18

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Compare all timetables for the bus from Talca, ML to La Serena

Here is a selection of the cheapest bus trips from the schedule from Talca, ML to La Serena from various bus operators like FlixBus or Turbus for the next days.

today
$38
tomorrow
$18
Tuesday
$26
Wednesday
$20
Thursday
$26
Friday
$20
Saturday
$29

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Turbus 10h 0m 12:10 PM Talca, ML Central Bus Station 10:10 PM La Serena Avda. Fco de Aguirre Station  Premium Economy $38
  • Did you know that if you travel from Talca, ML to La Serena via Santiago, RM, you can save more than $21? You can find the corresponding connections below.
    • FlixBus
      12h 35m
      0
      4:45 PM
      Talca, ML
      Cruce Varoli
      8:25 PM
      Santiago, RM
      Terminal San Borja
      0
      FlixBus
      Economy
      $5
      • Waiting Time 2h 35m
    • Pluss Chile
      6h 20m
      0
      11:00 PM
      Santiago, RM
      Sur Bus Station
      5:20 AM
      La Serena
      Central Bus Station
      0
      Pluss Chile
      Premium Economy
      $12
    Travel time is 2h 35m longer, but you will save $21

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 12h 50m 11:30 AM Talca, ML Cruce Varoli 12:20 AM La Serena Central Bus Station  Economy $18
FlixBus 11h 30m 10:30 AM Talca, ML Cruce Varoli 10:00 PM La Serena Central Bus Station  Economy $21
FlixBus 11h 15m 4:45 PM Talca, ML Cruce Varoli 4:00 AM La Serena Central Bus Station  Economy $22
FlixBus 11h 40m 10:20 AM Talca, ML Ocho Sur/ Veintiuno y Medio Ote Bus Stop 10:00 PM La Serena Central Bus Station  Economy $25
FlixBus 13h 0m 11:20 AM Talca, ML Ocho Sur/ Veintiuno y Medio Ote Bus Stop 12:20 AM La Serena Central Bus Station  Economy $25

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 0m 11:20 AM Talca, ML Cruce Varoli 12:20 AM La Serena Central Bus Station  Economy $26
Turbus 10h 0m 12:10 PM Talca, ML Central Bus Station 10:10 PM La Serena Avda. Fco de Aguirre Station  Premium Economy $30
  • Did you know that if you travel from Coquimbo to Talca, ML via La Serena, you can save more than $15? You will find the corresponding connections below.
    • Save more than 58%
      0h 15m
      0 mi
      6:50 PM
      Coquimbo
      Bus Station
      7:05 PM
      La Serena
      Central Bus Station
      378 mi
      Talca, ML
      Premium Economy
      $11
  • Did you know that if you travel from Talca, ML to La Serena via Santiago, RM, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      12h 35m
      0
      4:45 PM
      Talca, ML
      Cruce Varoli
      8:25 PM
      Santiago, RM
      Terminal San Borja
      0
      FlixBus
      Economy
      $5
      • Waiting Time 2h 35m
    • Pluss Chile
      6h 20m
      0
      11:00 PM
      Santiago, RM
      Sur Bus Station
      5:20 AM
      La Serena
      Central Bus Station
      0
      Pluss Chile
      Premium Economy
      $12
    Travel time is 2h 35m longer, but you will save $9

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 0m 11:20 AM Talca, ML Ocho Sur/ Veintiuno y Medio Ote Bus Stop 12:20 AM La Serena Central Bus Station  Economy $20
Turbus 10h 0m 12:10 PM Talca, ML Central Bus Station 10:10 PM La Serena Avda. Fco de Aguirre Station  Premium Economy $30
  • Did you know that if you travel from Talca, ML to La Serena via Santiago, RM, you can save more than $3? You can find the corresponding connections below.
    • FlixBus
      9h 55m
      0
      10:30 AM
      Talca, ML
      Cruce Varoli
      1:50 PM
      Santiago, RM
      Terminal San Borja
      0
      FlixBus
      Business
      $5
      • Waiting Time 0h 25m
    • FlixBus
      6h 10m
      0
      2:15 PM
      Santiago, RM
      Terminal San Borja
      8:25 PM
      La Serena
      Central Bus Station
      0
      FlixBus
      Economy
      $12
    Travel Time is 0h 5m shorter, and you will save $3

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 0m 11:20 AM Talca, ML Cruce Varoli 12:20 AM La Serena Central Bus Station  Economy $26
FlixBus 11h 10m 4:50 PM Talca, ML Cruce Varoli 4:00 AM La Serena Central Bus Station  Economy $31
  • Did you know that if you travel from Talca, ML to La Serena via Santiago, RM, you can save more than $10? You can find the corresponding connections below.
    • FlixBus
      14h 5m
      0
      11:30 AM
      Talca, ML
      Cruce Varoli
      2:50 PM
      Santiago, RM
      Terminal San Borja
      0
      FlixBus
      Business
      $5
      • Waiting Time 3h 10m
    • Pullman Bus
      7h 35m
      0
      6:00 PM
      Santiago, RM
      Terminal San Borja
      1:35 AM
      La Serena
      El Sto, 1060
      0
      Pullman Bus
      First Class
      $11
    Travel time is 2h 55m longer, but you will save $10

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 0m 11:20 AM Talca, ML Cruce Varoli 12:20 AM La Serena Central Bus Station  Economy $20
FlixBus 11h 40m 10:20 AM Talca, ML Cruce Varoli 10:00 PM La Serena Central Bus Station  Economy $22
FlixBus 11h 10m 4:50 PM Talca, ML Cruce Varoli 4:00 AM La Serena Central Bus Station  Economy $23
Turbus 10h 0m 12:10 PM Talca, ML Central Bus Station 10:10 PM La Serena Avda. Fco de Aguirre Station  Premium Economy $38
  • Did you know that if you travel from Talca, ML to La Serena via Santiago, RM, you can save more than $4? You can find the corresponding connections below.
    • FlixBus
      14h 5m
      0
      11:30 AM
      Talca, ML
      Cruce Varoli
      2:50 PM
      Santiago, RM
      Terminal San Borja
      0
      FlixBus
      Business
      $5
      • Waiting Time 3h 10m
    • Pullman Bus
      7h 35m
      0
      6:00 PM
      Santiago, RM
      Terminal San Borja
      1:35 AM
      La Serena
      El Sto, 1060
      0
      Pullman Bus
      First Class
      $11
    Travel time is 4h 5m longer, but you will save $4

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 0m 11:20 AM Talca, ML Ocho Sur/ Veintiuno y Medio Ote Bus Stop 12:20 AM La Serena Central Bus Station  Economy $29
Turbus 10h 0m 12:10 PM Talca, ML Central Bus Station 10:10 PM La Serena Avda. Fco de Aguirre Station  Premium Economy $30
FlixBus 11h 10m 4:50 PM Talca, ML Ocho Sur/ Veintiuno y Medio Ote Bus Stop 4:00 AM La Serena Central Bus Station  Economy $32
  • Did you know that if you travel from Talca, ML to La Serena via Santiago, RM, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      14h 5m
      0
      11:30 AM
      Talca, ML
      Cruce Varoli
      2:50 PM
      Santiago, RM
      Terminal San Borja
      0
      FlixBus
      Business
      $5
      • Waiting Time 3h 10m
    • Pullman Bus
      7h 35m
      0
      6:00 PM
      Santiago, RM
      Terminal San Borja
      1:35 AM
      La Serena
      El Sto, 1060
      0
      Pullman Bus
      First Class
      $11
    Travel time is 4h 5m longer, but you will save $13

Best Price Offer: The price for the cheapest bus from Talca, ML to La Serena is $18 on 10/19/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Talca, ML and La Serena

See here how frequent the connections between Talca, ML and La Serena are, during different times and days of the week.
Friday is the busiest day, with more than 7 daily buses from Talca, ML to La Serena. Sunday has instead the fewest connections, with only 1 daily coaches between Talca, ML and La Serena.
The busiest time of the day is the Morning, with 13 buses from Talca, ML to La Serena, while Afternoon sees the fewest connections between Talca, ML and La Serena, with 11 offers.

Facts about the bus from Talca, ML to La Serena

Compare all providers like FlixBus and Turbus that travel 3 times every day by bus from Talca, ML to La Serena in one click! Book your bus ticket from Talca, ML to La Serena starting from $18!

Cheapest Bus $18
Fastest Bus 10h 0m
Earliest Bus 12:10 PM
Latest Bus 4:50 PM
Daily Bus Routes 3 Ø
Distance 382.3 miles
Bus Companies FlixBus and Turbus

Cheapest bus connections from Talca, ML to La Serena

Every day, 3 buses from 2 bus companies leave Talca, ML for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/18/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
$38
Monday 10/19
$18
Tuesday 10/20
$26
Wednesday 10/21
$20
Thursday 10/22
$26
Friday 10/23
$20
Saturday 10/24
$30
Sunday 10/25
$33
Monday 10/26
$30
Tuesday 10/27
$30
Wednesday 10/28
$30
Thursday 10/29
$28
Friday 10/30
$25
Saturday 10/31
$23
Sunday 11/01
Monday 11/02
$33
Tuesday 11/03
Wednesday 11/04
$27
Thursday 11/05
$28
Friday 11/06
$28
Saturday 11/07
$28
Sunday 11/08
$34
Monday 11/09
$30
Tuesday 11/10
$20
Wednesday 11/11
$30
Thursday 11/12
$30
Friday 11/13
Saturday 11/14

The cheapest time to travel from Talca, ML to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Talca, ML to La Serena, for the next 30 days.
With a price starting from $18, Monday is the cheapest day for a bus from Talca, ML to La Serena. Sunday instead is the most expensive day with prices starting from $33.
Morning is the cheapest day time for bus tickets from Talca, ML to La Serena, with $18. Afternoon is the most expensive time of the day with prices starting from $22.

How to save money travelling from Talca, ML to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Talca, ML to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Talca, ML to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Talca, ML to La Serena are also emptier.

All bus stations and stops in Talca, ML and La Serena

In the map below, you can see where to find all bus stations in Talca, ML and La Serena.

Service and Comfort on the bus from Talca, ML to La Serena

Want to know which seat classes are available on the buses from Talca, ML to La Serena? Or which bus companies serve the route Talca, ML to La Serena? Below you will find answers to your questions.

FAQs about the Talca, ML to La Serena bus

How much does a Talca, ML La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $18 and takes 12h 50m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Talca, ML to La Serena?

This route is offered by 2 companies with a range of ticket prices between $18 and $38. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Talca, ML to La Serena each day?

Every day, the Talca, ML to La Serena bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Talca, ML to La Serena take?

The fastest bus from Talca, ML to La Serena is offered by Turbus and takes 10h 0m. Bus tickets for this connection cost $38. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Talca, ML to La Serena?

The earliest bus arriving in La Serena from Talca, ML starts at 12:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Talca, ML to La Serena?

The latest bus trip departing from Talca, ML for La Serena starts at 4:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Talca, ML La Serena route?

When traveling by bus from Talca, ML to La Serena, passengers can travel with FlixBus and Turbus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Talca, ML and La Serena?

You can check all the direct connections between Talca, ML and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Turbus.

What can I take with me on the Talca, ML to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Talca, ML La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Talca, ML La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Talca, ML to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Talca, ML to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Talca, ML and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Talca, ML to La Serena?

Prices and availability for 3 trips between Talca, ML and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Talca, ML to La Serena

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Talca, ML and to La Serena

Here’s an overview of the most popular bus routes to Talca, ML and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Talca, ML from Chillán Bus to Talca, ML from Chillán
Buses Rancagua to Talca, ML Buses Rancagua to Talca, ML
Bus to Talca, ML from Temuco Bus to Talca, ML from Temuco
Bus Viña del Mar - Talca, ML Bus Viña del Mar - Talca, ML
From Sierra Gorda to La Serena bus From Sierra Gorda to La Serena bus
Bus Ovalle - La Serena Bus Ovalle - La Serena
Buses Alto Hospicio to La Serena Buses Alto Hospicio to La Serena
Buses from Curicó to La Serena Buses from Curicó to La Serena
CheckMyBus › Buses in Chile › Bus to Talca, ML › Bus to La Serena

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