Bus Tlaquepaque to Mexico City: Compare prices and save money

Compare all timetables for the bus from Tlaquepaque to Mexico City

Here is a selection of the cheapest bus trips from the schedule from Tlaquepaque to Mexico City from various bus operators like ACN Autobuses for the next days.

today

$38

tomorrow

$37

Saturday

$38

Sunday

$37

Monday

$37

Tuesday

$38

Wednesday

$37

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ACN Autobuses	7h 5m	10:00 PM	Tlaquepaque	Central bus station	5:05 AM	Mexico City	Instituto Politécnico Nacional Bus Stop		Economy	$38	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/19/2026 10:00:00 PM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 3/20/2026 5:05:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 5m
	ACN Autobuses	7h 30m	10:00 PM	Tlaquepaque	Central bus station	5:30 AM	Mexico City	Calz. Ignacio Zaragoza		Economy	$38	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/19/2026 10:00:00 PM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 3/20/2026 5:30:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 30m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ACN Autobuses	7h 5m	10:00 PM	Tlaquepaque	Central bus station	5:05 AM	Mexico City	Instituto Politécnico Nacional Bus Stop		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/20/2026 10:00:00 PM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 3/21/2026 5:05:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 5m
	ACN Autobuses	7h 30m	10:00 PM	Tlaquepaque	Central bus station	5:30 AM	Mexico City	Calz. Ignacio Zaragoza		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/20/2026 10:00:00 PM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 3/21/2026 5:30:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 30m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ACN Autobuses	7h 5m	10:00 PM	Tlaquepaque	Central bus station	5:05 AM	Mexico City	Instituto Politécnico Nacional Bus Stop		Economy	$38	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/21/2026 10:00:00 PM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 3/22/2026 5:05:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 5m
	ACN Autobuses	7h 30m	10:00 PM	Tlaquepaque	Central bus station	5:30 AM	Mexico City	Calz. Ignacio Zaragoza		Economy	$38	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/21/2026 10:00:00 PM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 3/22/2026 5:30:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 30m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ACN Autobuses	7h 5m	10:00 PM	Tlaquepaque	Central bus station	5:05 AM	Mexico City	Instituto Politécnico Nacional Bus Stop		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/22/2026 10:00:00 PM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 3/23/2026 5:05:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 5m
	ACN Autobuses	7h 30m	10:00 PM	Tlaquepaque	Central bus station	5:30 AM	Mexico City	Calz. Ignacio Zaragoza		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/22/2026 10:00:00 PM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 3/23/2026 5:30:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 30m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ACN Autobuses	7h 5m	10:00 PM	Tlaquepaque	Central bus station	5:05 AM	Mexico City	Instituto Politécnico Nacional Bus Stop		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/23/2026 10:00:00 PM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 3/24/2026 5:05:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 5m
	ACN Autobuses	7h 30m	10:00 PM	Tlaquepaque	Central bus station	5:30 AM	Mexico City	Calz. Ignacio Zaragoza		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/23/2026 10:00:00 PM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 3/24/2026 5:30:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 30m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ACN Autobuses	7h 30m	10:00 PM	Tlaquepaque	Central bus station	5:30 AM	Mexico City	Calz. Ignacio Zaragoza		Economy	$38	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/24/2026 10:00:00 PM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 3/25/2026 5:30:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 30m
	ACN Autobuses	7h 5m	10:00 PM	Tlaquepaque	Central bus station	5:05 AM	Mexico City	Instituto Politécnico Nacional Bus Stop		Economy	$38	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/24/2026 10:00:00 PM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 3/25/2026 5:05:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 5m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ACN Autobuses	7h 30m	10:00 PM	Tlaquepaque	Central bus station	5:30 AM	Mexico City	Calz. Ignacio Zaragoza		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/25/2026 10:00:00 PM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 3/26/2026 5:30:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 30m
	ACN Autobuses	7h 5m	10:00 PM	Tlaquepaque	Central bus station	5:05 AM	Mexico City	Instituto Politécnico Nacional Bus Stop		Economy	$37	A Bus from ACN Autobuses goes from Central bus station, Tlaquepaque (Mexico) at 3/25/2026 10:00:00 PM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 3/26/2026 5:05:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 5m

Best Price Offer: The price for the cheapest bus from Tlaquepaque to Mexico City is $37 on 3/20/2026. Flexible travelers save on ticket prices.

Facts about the bus from Tlaquepaque to Mexico City

Compare all providers like ACN Autobuses that travel 2 times every day by bus from Tlaquepaque to Mexico City in one click! Book your bus ticket from Tlaquepaque to Mexico City starting from $37!

Cheapest Bus	$37
Fastest Bus	7h 5m
Earliest Bus	10:00 PM
Latest Bus	10:00 PM
Daily Bus Routes	2 Ø
Distance	283.5 miles
Bus Companies	ACN Autobuses

Cheapest bus connections from Tlaquepaque to Mexico City

Every day, 2 buses from 1 bus companies leave Tlaquepaque for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/15

Monday 03/16

Tuesday 03/17

Wednesday 03/18

Thursday 03/19

$38

Friday 03/20

$37

Saturday 03/21

$38

Sunday 03/22

$37

Monday 03/23

$37

Tuesday 03/24

$38

Wednesday 03/25

$37

Thursday 03/26

$37

Friday 03/27

$37

Saturday 03/28

$38

Sunday 03/29

$37

Monday 03/30

$38

Tuesday 03/31

$37

Wednesday 04/01

$37

Thursday 04/02

$37

Friday 04/03

$37

Saturday 04/04

$38

Sunday 04/05

$37

Monday 04/06

$37

Tuesday 04/07

$38

Wednesday 04/08

$37

Thursday 04/09

$38

Friday 04/10

$37

Saturday 04/11

How to save money travelling from Tlaquepaque to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tlaquepaque to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tlaquepaque to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tlaquepaque to Mexico City are also emptier.

All bus stations and stops in Tlaquepaque and Mexico City

In the map below, you can see where to find all bus stations in Tlaquepaque and Mexico City.

Central bus station

Carlos Salgado 6374

Tren Ligero Estación Periférico Sur

Carlos Salgado

Romita

Calle Independencia Bus Station

Calle Independencia Calle Independencia

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Terminal del Sur

Av. Taxqueña 1320

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Eje Central Bus Stop

Avenida Lázaro Cárdenas & Calle Poniente 112 Avenida Lázaro Cárdenas & Calle Poniente 112

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Tlaquepaque to Mexico City? Compare all modes of transports from Tlaquepaque to Mexico City.

Service and Comfort on the bus from Tlaquepaque to Mexico City

Want to know which seat classes are available on the buses from Tlaquepaque to Mexico City? Or which bus companies serve the route Tlaquepaque to Mexico City? Below you will find answers to your questions.

FAQs about the Tlaquepaque to Mexico City bus

How much does a Tlaquepaque Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $37 and takes 7h 5m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from Tlaquepaque to Mexico City?

This route is offered by 1 companies with a range of ticket prices between $37 and $38. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from Tlaquepaque to Mexico City each day?

Every day, the Tlaquepaque to Mexico City bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tlaquepaque to Mexico City take?

The fastest bus from Tlaquepaque to Mexico City is offered by ACN Autobuses and takes 7h 5m. Bus tickets for this connection cost $38. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tlaquepaque to Mexico City?

The earliest bus arriving in Mexico City from Tlaquepaque starts at 10:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tlaquepaque to Mexico City?

The latest bus trip departing from Tlaquepaque for Mexico City starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tlaquepaque Mexico City route?

When traveling by bus from Tlaquepaque to Mexico City, passengers can travel with ACN Autobuses. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tlaquepaque and Mexico City?

You can check all the direct connections between Tlaquepaque and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ACN Autobuses.

What can I take with me on the Tlaquepaque to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tlaquepaque Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tlaquepaque Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tlaquepaque to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from Tlaquepaque to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Tlaquepaque and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tlaquepaque to Mexico City?

Prices and availability for 2 trips between Tlaquepaque and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tlaquepaque to Mexico City

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tlaquepaque and to Mexico City

Here’s an overview of the most popular bus routes to Tlaquepaque and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!