Bus Tucson, AZ to Greenville, SC: Compare prices and save money

Compare all timetables for the bus from Tucson, AZ to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Tucson, AZ to Greenville, SC from various bus operators like Greyhound US or FlixBus for the next days.

today

$167

tomorrow

Wednesday

$198

Thursday

$179

Friday

$171

Saturday

$181

Sunday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	42h 5m	9:55 AM	Tucson, AZ	Greyhound Bus Station	7:00 AM	Greenville, SC	Woodruff Rd		Economy	$167	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/20/2026 9:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/22/2026 7:00:00 AM. 50 Economy ticket for $167 per person are available. Travel duration is 42h 5m
	Greyhound US	46h 30m	8:25 PM	Tucson, AZ	Greyhound Bus Station	9:55 PM	Greenville, SC	Woodruff Rd		Economy	$167	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/20/2026 8:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/22/2026 9:55:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 46h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	46h 30m	8:25 PM	Tucson, AZ	Greyhound Bus Station	9:55 PM	Greenville, SC	Woodruff Rd	Economy	$198	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/22/2026 8:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/24/2026 9:55:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 46h 30m
FlixBus	55h 10m	6:00 AM	Tucson, AZ	University of Arizona	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$199	A Bus from FlixBus goes from University of Arizona, Tucson, AZ (USA) at 4/22/2026 6:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/24/2026 4:10:00 PM. 50 Economy ticket for $199 per person are available. Travel duration is 55h 10m
Greyhound US	42h 5m	9:55 AM	Tucson, AZ	Greyhound Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$201	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/22/2026 9:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/24/2026 7:00:00 AM. 50 Economy ticket for $201 per person are available. Travel duration is 42h 5m

Did you know that if you travel from Tucson, AZ to Greenville, SC via Birmingham, AL, you can save more than $28? You can find the corresponding connections below.
- Greyhound US
  
  42h 5m
  
  0
  
  9:55 AM
  
  Tucson, AZ
  Greyhound Bus Station
  
  10:20 PM
  
  Birmingham, AL
  MAX Central Station
  
  0
  
  Economy
  
  $127
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/24/2026 9:55:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 4/25/2026 10:20:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 34h 25m
- Greyhound US
  
  7h 20m
  
  0
  
  10:40 PM
  
  Birmingham, AL
  MAX Central Station
  
  7:00 AM
  
  Greenville, SC
  Woodruff Rd
  
  0
  
  Economy
  
  $43
  
  A Bus from Greyhound US goes from MAX Central Station, Birmingham, AL (USA) at 4/25/2026 10:40:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/26/2026 7:00:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 20m
Travel Time is 3h 0m shorter, and you will save $28

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	55h 10m	6:00 AM	Tucson, AZ	University of Arizona	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$179	A Bus from FlixBus goes from University of Arizona, Tucson, AZ (USA) at 4/23/2026 6:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/25/2026 4:10:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 55h 10m
Greyhound US	46h 30m	8:25 PM	Tucson, AZ	Greyhound Bus Station	9:55 PM	Greenville, SC	Woodruff Rd	Economy	$180	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/23/2026 8:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/25/2026 9:55:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 46h 30m
Greyhound US	42h 5m	9:55 AM	Tucson, AZ	Greyhound Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$186	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/23/2026 9:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/25/2026 7:00:00 AM. 50 Economy ticket for $186 per person are available. Travel duration is 42h 5m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 5m	9:55 AM	Tucson, AZ	Greyhound Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$171	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/24/2026 9:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/26/2026 7:00:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 42h 5m
Greyhound US	46h 30m	8:25 PM	Tucson, AZ	Greyhound Bus Station	9:55 PM	Greenville, SC	Woodruff Rd	Economy	$171	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/24/2026 8:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/26/2026 9:55:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 46h 30m
FlixBus	55h 10m	6:00 AM	Tucson, AZ	University of Arizona	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$172	A Bus from FlixBus goes from University of Arizona, Tucson, AZ (USA) at 4/24/2026 6:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/26/2026 4:10:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 55h 10m
FlixBus	76h 30m	8:40 AM	Tucson, AZ	University of Arizona	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$177	A Bus from FlixBus goes from University of Arizona, Tucson, AZ (USA) at 4/24/2026 8:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/27/2026 4:10:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 76h 30m
FlixBus	76h 50m	8:20 AM	Tucson, AZ	East Tucson	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$177	A Bus from FlixBus goes from East Tucson, Tucson, AZ (USA) at 4/24/2026 8:20:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/27/2026 4:10:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 76h 50m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 5m	9:55 AM	Tucson, AZ	Greyhound Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$181	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/25/2026 9:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/27/2026 7:00:00 AM. 50 Economy ticket for $181 per person are available. Travel duration is 42h 5m
FlixBus	55h 10m	6:00 AM	Tucson, AZ	University of Arizona	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$183	A Bus from FlixBus goes from University of Arizona, Tucson, AZ (USA) at 4/25/2026 6:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 4/27/2026 4:10:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 55h 10m
Greyhound US	46h 30m	8:25 PM	Tucson, AZ	Greyhound Bus Station	9:55 PM	Greenville, SC	Woodruff Rd	Economy	$193	A Bus from Greyhound US goes from Greyhound Bus Station, Tucson, AZ (USA) at 4/25/2026 8:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 4/27/2026 9:55:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 46h 30m

Best Price Offer: The price for the cheapest bus from Tucson, AZ to Greenville, SC is $128 on 4/21/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Tucson, AZ and Greenville, SC

See here how frequent the connections between Tucson, AZ and Greenville, SC are, during different times and days of the week.

Wednesday is the busiest day, with more than 6 daily buses from Tucson, AZ to Greenville, SC. Thursday has instead the fewest connections, with only 3 daily coaches between Tucson, AZ and Greenville, SC.

The busiest time of the day is the Morning, with 15 buses from Tucson, AZ to Greenville, SC, while Evening sees the fewest connections between Tucson, AZ and Greenville, SC, with 7 offers.

Facts about the bus from Tucson, AZ to Greenville, SC

Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from Tucson, AZ to Greenville, SC in one click! Book your bus ticket from Tucson, AZ to Greenville, SC starting from $128!

Cheapest Bus	$128
Fastest Bus	45h 5m
Earliest Bus	9:55 AM
Latest Bus	8:25 PM
Daily Bus Routes	4 Ø
Distance	1,648.2 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Tucson, AZ to Greenville, SC

Every day, 4 buses from 2 bus companies leave Tucson, AZ for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$171

Tuesday 04/21

$128

Wednesday 04/22

$198

Thursday 04/23

$179

Friday 04/24

$171

Saturday 04/25

$181

Sunday 04/26

$128

Monday 04/27

$163

Tuesday 04/28

$189

Wednesday 04/29

$173

Thursday 04/30

$128

Friday 05/01

$160

Saturday 05/02

$160

Sunday 05/03

$154

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$174

Saturday 05/09

$172

Sunday 05/10

$167

Monday 05/11

$154

Tuesday 05/12

Wednesday 05/13

$183

Thursday 05/14

$171

Friday 05/15

$174

Saturday 05/16

The cheapest time to travel from Tucson, AZ to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Tucson, AZ to Greenville, SC, for the next 30 days.

With a price starting from $128, Thursday is the cheapest day for a bus from Tucson, AZ to Greenville, SC. Wednesday instead is the most expensive day with prices starting from $173.

Morning is the cheapest day time for bus tickets from Tucson, AZ to Greenville, SC, with $167. Morning is the most expensive time of the day with prices starting from $167.

How to save money travelling from Tucson, AZ to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tucson, AZ to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tucson, AZ to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tucson, AZ to Greenville, SC are also emptier.

All bus stations and stops in Tucson, AZ and Greenville, SC

In the map below, you can see where to find all bus stations in Tucson, AZ and Greenville, SC.

Greyhound Bus Station

E 12th St 801

East Tucson

University of Arizona

6th Av/Pennington (NE) Bus Station

6th Av/Pennington (NE) 6th Av/Pennington (NE)

Roy Laos Transit Center

W Irvington Rd 205

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

N Church St

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

Service and Comfort on the bus from Tucson, AZ to Greenville, SC

Want to know which seat classes are available on the buses from Tucson, AZ to Greenville, SC? Or which bus companies serve the route Tucson, AZ to Greenville, SC? Below you will find answers to your questions.

FAQs about the Tucson, AZ to Greenville, SC bus

How much does a Tucson, AZ Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $128 and takes 45h 5m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Tucson, AZ to Greenville, SC?

This route is offered by 2 companies with a range of ticket prices between $128 and $205. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Tucson, AZ to Greenville, SC each day?

Every day, the Tucson, AZ to Greenville, SC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tucson, AZ to Greenville, SC take?

The fastest bus from Tucson, AZ to Greenville, SC is offered by Greyhound US and takes 45h 5m. Bus tickets for this connection cost $167. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tucson, AZ to Greenville, SC?

The earliest bus arriving in Greenville, SC from Tucson, AZ starts at 9:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tucson, AZ to Greenville, SC?

The latest bus trip departing from Tucson, AZ for Greenville, SC starts at 8:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tucson, AZ Greenville, SC route?

When traveling by bus from Tucson, AZ to Greenville, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tucson, AZ and Greenville, SC?

You can check all the direct connections between Tucson, AZ and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Tucson, AZ to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tucson, AZ Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tucson, AZ Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tucson, AZ to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Tucson, AZ to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Tucson, AZ and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tucson, AZ to Greenville, SC?

Prices and availability for 4 trips between Tucson, AZ and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tucson, AZ to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tucson, AZ and to Greenville, SC

Here’s an overview of the most popular bus routes to Tucson, AZ and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!