Bus Columbus, OH to San Diego - Compare all Companies

Compare all timetables for the bus from Columbus, OH to San Diego

Here is a selection of the cheapest bus trips from the schedule from Columbus, OH to San Diego from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$255

Saturday

$221

Sunday

Monday

$221

Tuesday

Wednesday

$310

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	67h 5m	10:05 PM	Columbus, OH	E Main St & S Lazelle St	2:10 PM	San Diego	Old Town Transit Center	Economy	$255	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/5/2025 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 2:10:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 67h 5m
Greyhound US	66h 35m	10:05 PM	Columbus, OH	E Main St & S Lazelle St	1:40 PM	San Diego	La Jolla Village	Economy	$255	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/5/2025 10:05:00 PM to La Jolla Village, San Diego (USA) arriving at 12/8/2025 1:40:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 66h 35m
FlixBus	65h 10m	11:30 PM	Columbus, OH	ABM Public Parking	1:40 PM	San Diego	La Jolla Village	Economy	$264	A Bus from FlixBus goes from ABM Public Parking, Columbus, OH (USA) at 12/5/2025 11:30:00 PM to La Jolla Village, San Diego (USA) arriving at 12/8/2025 1:40:00 PM. 50 Economy ticket for $264 per person are available. Travel duration is 65h 10m
Greyhound US	60h 20m	4:50 AM	Columbus, OH	E Main St & S Lazelle St	2:10 PM	San Diego	Old Town Transit Center	Economy	$268	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/5/2025 4:50:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $268 per person are available. Travel duration is 60h 20m
FlixBus	65h 40m	11:30 PM	Columbus, OH	ABM Public Parking	2:10 PM	San Diego	Old Town Transit Center	Economy	$270	A Bus from FlixBus goes from ABM Public Parking, Columbus, OH (USA) at 12/5/2025 11:30:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 2:10:00 PM. 50 Economy ticket for $270 per person are available. Travel duration is 65h 40m

Did you know that if you travel from Columbus, OH to San Diego via St. Louis, MO, you can save more than $52? You can find the corresponding connections below.
- FlixBus
  
  63h 55m
  
  0
  
  4:50 AM
  
  Columbus, OH
  E Main St & S Lazelle St
  
  3:20 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $50
  
  A Bus from FlixBus goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/6/2025 4:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/6/2025 3:20:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 11h 30m
- FlixBus
  
  51h 45m
  
  0
  
  4:00 PM
  
  St. Louis, MO
  Gateway Station
  
  5:45 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $153
  
  A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 5:45:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 51h 45m
Travel time is 6h 35m longer, but you will save $52

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	60h 50m	4:50 AM	Columbus, OH	E Main St & S Lazelle St	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$221	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/6/2025 4:50:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/8/2025 2:40:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 60h 50m
Greyhound US	54h 50m	2:30 PM	Columbus, OH	E Main St & S Lazelle St	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$273	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/6/2025 2:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/8/2025 6:20:00 PM. 50 Economy ticket for $273 per person are available. Travel duration is 54h 50m
FlixBus	59h 35m	9:45 AM	Columbus, OH	ABM Public Parking	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$276	A Bus from FlixBus goes from ABM Public Parking, Columbus, OH (USA) at 12/6/2025 9:45:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/8/2025 6:20:00 PM. 50 Economy ticket for $276 per person are available. Travel duration is 59h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	67h 35m	10:05 PM	Columbus, OH	E Main St & S Lazelle St	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$221	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/8/2025 10:05:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/11/2025 2:40:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 67h 35m
Greyhound US	55h 15m	2:30 PM	Columbus, OH	E Main St & S Lazelle St	6:45 PM	San Diego	San Ysidro Transit Center	Economy	$241	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/8/2025 2:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/10/2025 6:45:00 PM. 50 Economy ticket for $241 per person are available. Travel duration is 55h 15m
FlixBus	60h 0m	9:45 AM	Columbus, OH	ABM Public Parking	6:45 PM	San Diego	San Ysidro Transit Center	Economy	$242	A Bus from FlixBus goes from ABM Public Parking, Columbus, OH (USA) at 12/8/2025 9:45:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/10/2025 6:45:00 PM. 50 Economy ticket for $242 per person are available. Travel duration is 60h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	59h 50m	4:50 AM	Columbus, OH	E Main St & S Lazelle St	1:40 PM	San Diego	La Jolla Village	Economy	$310	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/10/2025 4:50:00 AM to La Jolla Village, San Diego (USA) arriving at 12/12/2025 1:40:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 59h 50m
FlixBus	65h 10m	11:30 PM	Columbus, OH	ABM Public Parking	1:40 PM	San Diego	La Jolla Village	Economy	$310	A Bus from FlixBus goes from ABM Public Parking, Columbus, OH (USA) at 12/10/2025 11:30:00 PM to La Jolla Village, San Diego (USA) arriving at 12/13/2025 1:40:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 65h 10m
Greyhound US	67h 5m	10:05 PM	Columbus, OH	E Main St & S Lazelle St	2:10 PM	San Diego	Old Town Transit Center	Economy	$311	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/10/2025 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 2:10:00 PM. 50 Economy ticket for $311 per person are available. Travel duration is 67h 5m
Greyhound US	66h 35m	10:05 PM	Columbus, OH	E Main St & S Lazelle St	1:40 PM	San Diego	La Jolla Village	Economy	$311	A Bus from Greyhound US goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/10/2025 10:05:00 PM to La Jolla Village, San Diego (USA) arriving at 12/13/2025 1:40:00 PM. 50 Economy ticket for $311 per person are available. Travel duration is 66h 35m
FlixBus	73h 45m	11:30 PM	Columbus, OH	ABM Public Parking	10:15 PM	San Diego	Seaport Village	Economy	$312	A Bus from FlixBus goes from ABM Public Parking, Columbus, OH (USA) at 12/10/2025 11:30:00 PM to Seaport Village, San Diego (USA) arriving at 12/13/2025 10:15:00 PM. 50 Economy ticket for $312 per person are available. Travel duration is 73h 45m

Did you know that if you travel from Columbus, OH to San Diego via St. Louis, MO, you can save more than $107? You can find the corresponding connections below.
- FlixBus
  
  63h 55m
  
  0
  
  4:50 AM
  
  Columbus, OH
  E Main St & S Lazelle St
  
  3:20 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $50
  
  A Bus from FlixBus goes from E Main St & S Lazelle St, Columbus, OH (USA) at 12/6/2025 4:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/6/2025 3:20:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 11h 30m
- FlixBus
  
  51h 45m
  
  0
  
  4:00 PM
  
  St. Louis, MO
  Gateway Station
  
  5:45 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $153
  
  A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/6/2025 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 5:45:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 51h 45m
Travel time is 7h 5m longer, but you will save $107

Best Price Offer: The price for the cheapest bus from Columbus, OH to San Diego is $221 on 12/3/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Columbus, OH and San Diego

See here how frequent the connections between Columbus, OH and San Diego are, during different times and days of the week.

Wednesday is the busiest day, with more than 15 daily buses from Columbus, OH to San Diego. Monday has instead the fewest connections, with only 3 daily coaches between Columbus, OH and San Diego.

The busiest time of the day is the Evening, with 11 buses from Columbus, OH to San Diego, while Night sees the fewest connections between Columbus, OH and San Diego, with 5 offers.

Facts about the bus from Columbus, OH to San Diego

Compare all providers like Greyhound US and FlixBus that travel 9 times every day by bus from Columbus, OH to San Diego in one click! Book your bus ticket from Columbus, OH to San Diego starting from $221!

Cheapest Bus	$221
Fastest Bus	51h 5m
Earliest Bus	4:50 AM
Latest Bus	11:30 PM
Daily Bus Routes	9 Ø
Distance	1,953.2 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Columbus, OH to San Diego

Every day, 9 buses from 2 bus companies leave Columbus, OH for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$255

Saturday 12/06

$221

Sunday 12/07

Monday 12/08

$221

Tuesday 12/09

Wednesday 12/10

$310

Thursday 12/11

$221

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Columbus, OH to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Columbus, OH to San Diego, for the next 30 days.

With a price starting from $221, Monday is the cheapest day for a bus from Columbus, OH to San Diego. Wednesday instead is the most expensive day with prices starting from $310.

Evening is the cheapest day time for bus tickets from Columbus, OH to San Diego, with $221. Morning is the most expensive time of the day with prices starting from $242.

How to save money travelling from Columbus, OH to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Columbus, OH to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Columbus, OH to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Columbus, OH to San Diego are also emptier.

All bus stations and stops in Columbus, OH and San Diego

In the map below, you can see where to find all bus stations in Columbus, OH and San Diego.

Greyhound Bus Station

E Town St 111

University

N High St 1739

N Wilson

ABM Public Parking

E Rich Street 100

E Main St & S Lazelle St

E Main St 139

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Columbus, OH to San Diego

Want to know which seat classes are available on the buses from Columbus, OH to San Diego? Or which bus companies serve the route Columbus, OH to San Diego? Below you will find answers to your questions.

FAQs about the Columbus, OH to San Diego bus

How much does a Columbus, OH San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $221 and takes 64h 35m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Columbus, OH to San Diego?

This route is offered by 2 companies with a range of ticket prices between $221 and $327. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Columbus, OH to San Diego each day?

Every day, the Columbus, OH to San Diego bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Columbus, OH to San Diego take?

The fastest bus from Columbus, OH to San Diego is offered by Greyhound US and takes 51h 5m. Bus tickets for this connection cost $279. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Columbus, OH to San Diego?

The earliest bus arriving in San Diego from Columbus, OH starts at 4:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Columbus, OH to San Diego?

The latest bus trip departing from Columbus, OH for San Diego starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Columbus, OH San Diego route?

When traveling by bus from Columbus, OH to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Columbus, OH and San Diego?

You can check all the direct connections between Columbus, OH and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Columbus, OH to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Columbus, OH San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Columbus, OH San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Columbus, OH to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Columbus, OH to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Columbus, OH and to San Diego

Here’s an overview of the most popular bus routes to Columbus, OH and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!