Bus Detroit to San Diego - Compare all Companies

Compare all timetables for the bus from Detroit to San Diego

Here is a selection of the cheapest bus trips from the schedule from Detroit to San Diego from various bus operators like Greyhound US for the next days.

today

tomorrow

Sunday

Monday

$223

Tuesday

Wednesday

$221

Thursday

$221

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	66h 15m	11:25 PM	Detroit	Central Bus Station	2:40 PM	San Diego	San Ysidro Transit Center		Economy	$223	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/8/2025 11:25:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/11/2025 2:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 66h 15m
	Greyhound US	61h 25m	8:20 AM	Detroit	Central Bus Station	6:45 PM	San Diego	San Ysidro Transit Center		Economy	$241	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/8/2025 8:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/10/2025 6:45:00 PM. 50 Economy ticket for $241 per person are available. Travel duration is 61h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	66h 15m	11:25 PM	Detroit	Central Bus Station	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$221	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/10/2025 11:25:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/13/2025 2:40:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 66h 15m
Greyhound US	62h 40m	6:40 AM	Detroit	Central Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$234	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/10/2025 6:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/12/2025 6:20:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 62h 40m
Greyhound US	65h 45m	11:25 PM	Detroit	Central Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$294	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/10/2025 11:25:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 2:10:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 65h 45m
Greyhound US	65h 15m	11:25 PM	Detroit	Central Bus Station	1:40 PM	San Diego	La Jolla Village	Economy	$294	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/10/2025 11:25:00 PM to La Jolla Village, San Diego (USA) arriving at 12/13/2025 1:40:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 65h 15m
Greyhound US	73h 50m	11:25 PM	Detroit	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$298	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/10/2025 11:25:00 PM to Seaport Village, San Diego (USA) arriving at 12/13/2025 10:15:00 PM. 50 Economy ticket for $298 per person are available. Travel duration is 73h 50m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	66h 15m	11:25 PM	Detroit	Central Bus Station	2:40 PM	San Diego	San Ysidro Transit Center		Economy	$221	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/11/2025 11:25:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/14/2025 2:40:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 66h 15m
	Greyhound US	62h 40m	6:40 AM	Detroit	Central Bus Station	6:20 PM	San Diego	San Ysidro Transit Center		Economy	$226	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 12/11/2025 6:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/13/2025 6:20:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 62h 40m

Best Price Offer: The price for the cheapest bus from Detroit to San Diego is $221 on 12/10/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Detroit and San Diego

See here how frequent the connections between Detroit and San Diego are, during different times and days of the week.

Wednesday is the busiest day, with more than 11 daily buses from Detroit to San Diego. Monday has instead the fewest connections, with only 2 daily coaches between Detroit and San Diego.

The busiest time of the day is the Evening, with 8 buses from Detroit to San Diego, while Morning sees the fewest connections between Detroit and San Diego, with 7 offers.

Facts about the bus from Detroit to San Diego

Compare all providers like Greyhound US that travel 5 times every day by bus from Detroit to San Diego in one click! Book your bus ticket from Detroit to San Diego starting from $221!

Cheapest Bus	$221
Fastest Bus	58h 25m
Earliest Bus	8:20 AM
Latest Bus	11:25 PM
Daily Bus Routes	5 Ø
Distance	1,967.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Detroit to San Diego

Every day, 5 buses from 1 bus companies leave Detroit for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

Sunday 12/07

Monday 12/08

$223

Tuesday 12/09

Wednesday 12/10

$294

Thursday 12/11

$221

Friday 12/12

Saturday 12/13

$293

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$223

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Detroit to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Detroit to San Diego, for the next 30 days.

With a price starting from $221, Wednesday is the cheapest day for a bus from Detroit to San Diego. Monday instead is the most expensive day with prices starting from $223.

Evening is the cheapest day time for bus tickets from Detroit to San Diego, with $221. Morning is the most expensive time of the day with prices starting from $226.

How to save money travelling from Detroit to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Detroit to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Detroit to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Detroit to San Diego are also emptier.

All bus stations and stops in Detroit and San Diego

In the map below, you can see where to find all bus stations in Detroit and San Diego.

Central Bus Station

Howard St 1001

Amtrak

W Baltimore Ave 78

VA Medical Center Blue Deck

East Canfield Street (between John R. and Brush St.) 225

Park Avenue

Rosa Parks TC

Cass Ave 1310

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Detroit to San Diego

Want to know which seat classes are available on the buses from Detroit to San Diego? Or which bus companies serve the route Detroit to San Diego? Below you will find answers to your questions.

FAQs about the Detroit to San Diego bus

How much does a Detroit San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $221 and takes 63h 15m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Detroit to San Diego?

This route is offered by 1 companies with a range of ticket prices between $221 and $323. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Detroit to San Diego each day?

Every day, the Detroit to San Diego bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Detroit to San Diego take?

The fastest bus from Detroit to San Diego is offered by Greyhound US and takes 58h 25m. Bus tickets for this connection cost $241. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Detroit to San Diego?

The earliest bus arriving in San Diego from Detroit starts at 8:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Detroit to San Diego?

The latest bus trip departing from Detroit for San Diego starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Detroit San Diego route?

When traveling by bus from Detroit to San Diego, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Detroit and San Diego?

You can check all the direct connections between Detroit and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Detroit to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Detroit San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Detroit San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Detroit to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Detroit to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Detroit and to San Diego

Here’s an overview of the most popular bus routes to Detroit and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!