Bus Gainesville, FL to Louisville, KY

Compare all timetables for the bus from Gainesville, FL to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from Gainesville, FL to Louisville, KY from various bus operators like FlixBus or Greyhound US for the next days.

today

$110

tomorrow

$115

Saturday

Sunday

$139

Monday

Tuesday

Wednesday

$115

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 20m	12:20 PM	Gainesville, FL	Rosa Parks Transfer station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$110	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/18/2025 12:20:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/19/2025 4:40:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 16h 20m
FlixBus	16h 45m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$110	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/18/2025 2:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/19/2025 7:25:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 16h 45m
FlixBus	16h 35m	5:00 PM	Gainesville, FL	Rosa Parks Transfer station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$110	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/18/2025 5:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/19/2025 9:35:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 16h 35m
Greyhound US	24h 40m	1:30 PM	Gainesville, FL	Greyhound Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$126	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/18/2025 1:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/19/2025 2:10:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 24h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 10m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	7:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$115	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/19/2025 1:10:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/19/2025 7:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 18h 10m
Greyhound US	20h 20m	8:20 AM	Gainesville, FL	Greyhound Bus Station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$115	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/19/2025 8:20:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/20/2025 4:40:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 20m
FlixBus	16h 20m	12:20 PM	Gainesville, FL	Rosa Parks Transfer station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$117	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/19/2025 12:20:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/20/2025 4:40:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 16h 20m
FlixBus	16h 45m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$123	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/19/2025 2:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/20/2025 7:25:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 16h 45m
Greyhound US	17h 30m	8:00 AM	Gainesville, FL	Greyhound Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$137	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/19/2025 8:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/20/2025 1:30:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 17h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 20m	12:20 PM	Gainesville, FL	Rosa Parks Transfer station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$139	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/21/2025 12:20:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 4:40:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 16h 20m
FlixBus	16h 45m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$139	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/21/2025 2:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 7:25:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 16h 45m
FlixBus	16h 35m	5:00 PM	Gainesville, FL	Rosa Parks Transfer station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$139	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/21/2025 5:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 9:35:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 16h 35m
Greyhound US	24h 40m	1:30 PM	Gainesville, FL	Greyhound Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$139	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/21/2025 1:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 2:10:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 24h 40m
Greyhound US	17h 30m	8:00 AM	Gainesville, FL	Greyhound Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$140	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/21/2025 8:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 1:30:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 17h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 10m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	7:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$115	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/24/2025 1:10:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/24/2025 7:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 18h 10m
Greyhound US	20h 20m	8:20 AM	Gainesville, FL	Greyhound Bus Station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$115	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/24/2025 8:20:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 4:40:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 20m
Greyhound US	24h 40m	1:30 PM	Gainesville, FL	Greyhound Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$115	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/24/2025 1:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 2:10:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 24h 40m
FlixBus	16h 20m	12:20 PM	Gainesville, FL	Rosa Parks Transfer station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$117	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/24/2025 12:20:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 4:40:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 16h 20m
FlixBus	16h 45m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$117	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/24/2025 2:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 7:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 16h 45m

Best Price Offer: The price for the cheapest bus from Gainesville, FL to Louisville, KY is $104 on 12/16/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Gainesville, FL and Louisville, KY

See here how frequent the connections between Gainesville, FL and Louisville, KY are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Gainesville, FL to Louisville, KY. Thursday has instead the fewest connections, with only 5 daily coaches between Gainesville, FL and Louisville, KY.

The busiest time of the day is the Afternoon, with 16 buses from Gainesville, FL to Louisville, KY, while Night sees the fewest connections between Gainesville, FL and Louisville, KY, with 3 offers.

Facts about the bus from Gainesville, FL to Louisville, KY

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from Gainesville, FL to Louisville, KY in one click! Book your bus ticket from Gainesville, FL to Louisville, KY starting from $104!

Cheapest Bus	$104
Fastest Bus	16h 20m
Earliest Bus	12:20 PM
Latest Bus	10:40 PM
Daily Bus Routes	7 Ø
Distance	626.7 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Gainesville, FL to Louisville, KY

Every day, 7 buses from 2 bus companies leave Gainesville, FL for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$110

Friday 12/19

$115

Saturday 12/20

Sunday 12/21

$139

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$115

Thursday 12/25

Friday 12/26

$128

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Gainesville, FL to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from Gainesville, FL to Louisville, KY, for the next 30 days.

With a price starting from $110, Thursday is the cheapest day for a bus from Gainesville, FL to Louisville, KY. Sunday instead is the most expensive day with prices starting from $139.

Afternoon is the cheapest day time for bus tickets from Gainesville, FL to Louisville, KY, with $110. Evening is the most expensive time of the day with prices starting from $117.

How to save money travelling from Gainesville, FL to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Gainesville, FL to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Gainesville, FL to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Gainesville, FL to Louisville, KY are also emptier.

All bus stations and stops in Gainesville, FL and Louisville, KY

In the map below, you can see where to find all bus stations in Gainesville, FL and Louisville, KY.

Greyhound Bus Station

Northeast 23rd Avenue 101

North Walmart Supercenter Bus Stop

Westgate Plaza Bus Stop

Central Bus Station

University of Florida (Commuter Lot)

Gale Lemerand Dr

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Service and Comfort on the bus from Gainesville, FL to Louisville, KY

Want to know which seat classes are available on the buses from Gainesville, FL to Louisville, KY? Or which bus companies serve the route Gainesville, FL to Louisville, KY? Below you will find answers to your questions.

FAQs about the Gainesville, FL to Louisville, KY bus

How much does a Gainesville, FL Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $104 and takes 16h 20m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from Gainesville, FL to Louisville, KY?

This route is offered by 2 companies with a range of ticket prices between $104 and $155. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from Gainesville, FL to Louisville, KY each day?

Every day, the Gainesville, FL to Louisville, KY bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Gainesville, FL to Louisville, KY take?

The fastest bus from Gainesville, FL to Louisville, KY is offered by FlixBus and takes 16h 20m. Bus tickets for this connection cost $110. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Gainesville, FL to Louisville, KY?

The earliest bus arriving in Louisville, KY from Gainesville, FL starts at 12:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Gainesville, FL to Louisville, KY?

The latest bus trip departing from Gainesville, FL for Louisville, KY starts at 10:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Gainesville, FL Louisville, KY route?

When traveling by bus from Gainesville, FL to Louisville, KY, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Gainesville, FL and Louisville, KY?

You can check all the direct connections between Gainesville, FL and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Gainesville, FL to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Gainesville, FL Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Gainesville, FL Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Gainesville, FL to Louisville, KY on your planned travel date.

How does CheckMyBus find the best bus deals from Gainesville, FL to Louisville, KY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Gainesville, FL and Louisville, KY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Gainesville, FL to Louisville, KY?

Prices and availability for 7 trips between Gainesville, FL and Louisville, KY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Gainesville, FL to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Gainesville, FL and to Louisville, KY

Here’s an overview of the most popular bus routes to Gainesville, FL and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!