Which bus from Indianapolis to San Diego is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $189
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Compare all timetables for the bus from Indianapolis to San Diego

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to San Diego from various bus operators like FlixBus or Greyhound US for the next days.

today
$315
tomorrow
Monday
Tuesday
$315
Wednesday
Thursday
Friday
$329

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 57h 5m 8:35 AM Indianapolis Washington / Delaware 2:40 PM San Diego San Ysidro Transit Center  Economy $315
Greyhound US 54h 15m 11:25 AM Indianapolis Central Bus Station 2:40 PM San Diego San Ysidro Transit Center  Economy $316
FlixBus 63h 50m 11:30 PM Indianapolis Washington / Delaware 12:20 PM San Diego San Ysidro Transit Center  Economy $320
FlixBus 59h 50m 9:30 AM Indianapolis Washington / Delaware 6:20 PM San Diego San Ysidro Transit Center  Economy $359
Greyhound US 49h 15m 8:05 PM Indianapolis Central Bus Station 6:20 PM San Diego San Ysidro Transit Center  Economy $365

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 56h 35m 8:35 AM Indianapolis Washington / Delaware 2:10 PM San Diego Old Town Transit Center  Economy $315
FlixBus 56h 5m 8:35 AM Indianapolis Washington / Delaware 1:40 PM San Diego La Jolla Village  Economy $315
FlixBus 64h 40m 8:35 AM Indianapolis Washington / Delaware 10:15 PM San Diego Seaport Village  Economy $316
Greyhound US 53h 45m 11:25 AM Indianapolis Central Bus Station 2:10 PM San Diego Old Town Transit Center  Economy $316
Greyhound US 53h 15m 11:25 AM Indianapolis Central Bus Station 1:40 PM San Diego La Jolla Village  Economy $317
  • Did you know that if you travel from Indianapolis to San Diego via Kansas City, you can save more than $48? You can find the corresponding connections below.
    • Busbud
      68h 35m
      0
      8:05 PM
      Indianapolis
      Central Bus Station
      6:00 AM
      Kansas City
      Greyhound Bus Station
      0
      Busbud
      Economy
      $71
      • Waiting Time 16h 20m
    • FlixBus
      41h 20m
      0
      10:20 PM
      Kansas City
      Greyhound Bus Station
      1:40 PM
      San Diego
      La Jolla Village
      0
      FlixBus
      Economy
      $196
    Travel time is 18h 20m longer, but you will save $48

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 56h 35m 8:35 AM Indianapolis Washington / Delaware 2:10 PM San Diego Old Town Transit Center  Economy $329
FlixBus 56h 5m 8:35 AM Indianapolis Washington / Delaware 1:40 PM San Diego La Jolla Village  Economy $329
Greyhound US 53h 15m 11:25 AM Indianapolis Central Bus Station 1:40 PM San Diego La Jolla Village  Economy $346
Greyhound US 53h 45m 11:25 AM Indianapolis Central Bus Station 2:10 PM San Diego Old Town Transit Center  Economy $349
Greyhound US 73h 0m 8:10 PM Indianapolis Central Bus Station 6:10 PM San Diego Old Town Transit Center  Economy $372
  • Did you know that if you travel from Indianapolis to San Diego via Kansas City, you can save more than $62? You can find the corresponding connections below.
    • Busbud
      68h 35m
      0
      8:05 PM
      Indianapolis
      Central Bus Station
      6:00 AM
      Kansas City
      Greyhound Bus Station
      0
      Busbud
      Economy
      $71
      • Waiting Time 16h 20m
    • FlixBus
      41h 20m
      0
      10:20 PM
      Kansas City
      Greyhound Bus Station
      1:40 PM
      San Diego
      La Jolla Village
      0
      FlixBus
      Economy
      $196
    Travel time is 18h 20m longer, but you will save $62

Best Price Offer: The price for the cheapest bus from Indianapolis to San Diego is $189 on 12/10/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Indianapolis and San Diego

See here how frequent the connections between Indianapolis and San Diego are, during different times and days of the week.
Friday is the busiest day, with more than 18 daily buses from Indianapolis to San Diego. Saturday has instead the fewest connections, with only 5 daily coaches between Indianapolis and San Diego.
The busiest time of the day is the Evening, with 22 buses from Indianapolis to San Diego, while Afternoon sees the fewest connections between Indianapolis and San Diego, with 4 offers.

Facts about the bus from Indianapolis to San Diego

Compare all providers like FlixBus and Greyhound US that travel 13 times every day by bus from Indianapolis to San Diego in one click! Book your bus ticket from Indianapolis to San Diego starting from $189!

Cheapest Bus $189
Fastest Bus 45h 30m
Earliest Bus 8:35 AM
Latest Bus 11:30 PM
Daily Bus Routes 13 Ø
Distance 1,785.2 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Indianapolis to San Diego

Every day, 13 buses from 2 bus companies leave Indianapolis for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/13/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/07
Monday 12/08
Tuesday 12/09
Wednesday 12/10
Thursday 12/11
Friday 12/12
Saturday 12/13
$315
Sunday 12/14
Monday 12/15
Tuesday 12/16
$315
Wednesday 12/17
Thursday 12/18
Friday 12/19
$329
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27
Sunday 12/28
Monday 12/29
Tuesday 12/30
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03

The cheapest time to travel from Indianapolis to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Indianapolis to San Diego, for the next 30 days.
With a price starting from $315, Saturday is the cheapest day for a bus from Indianapolis to San Diego. Friday instead is the most expensive day with prices starting from $329.
Morning is the cheapest day time for bus tickets from Indianapolis to San Diego, with $315. Afternoon is the most expensive time of the day with prices starting from $431.

How to save money travelling from Indianapolis to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to San Diego are also emptier.

All bus stations and stops in Indianapolis and San Diego

In the map below, you can see where to find all bus stations in Indianapolis and San Diego.

Service and Comfort on the bus from Indianapolis to San Diego

Want to know which seat classes are available on the buses from Indianapolis to San Diego? Or which bus companies serve the route Indianapolis to San Diego? Below you will find answers to your questions.

FAQs about the Indianapolis to San Diego bus

How much does a Indianapolis San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $189 and takes 54h 5m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to San Diego?

This route is offered by 2 companies with a range of ticket prices between $189 and $471. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Indianapolis to San Diego each day?

Every day, the Indianapolis to San Diego bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to San Diego take?

The fastest bus from Indianapolis to San Diego is offered by Greyhound US and takes 45h 30m. Bus tickets for this connection cost $356. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to San Diego?

The earliest bus arriving in San Diego from Indianapolis starts at 8:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to San Diego?

The latest bus trip departing from Indianapolis for San Diego starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis San Diego route?

When traveling by bus from Indianapolis to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and San Diego?

You can check all the direct connections between Indianapolis and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Indianapolis to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 13 daily trips between Indianapolis and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to San Diego?

Prices and availability for 13 trips between Indianapolis and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to San Diego

Here’s an overview of the most popular bus routes to Indianapolis and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Dallas to Indianapolis bus From Dallas to Indianapolis bus
Buses Boston, MA to Indianapolis Buses Boston, MA to Indianapolis
Bus from Philadelphia to Indianapolis Bus from Philadelphia to Indianapolis
Bus Knoxville, TN - Indianapolis Bus Knoxville, TN - Indianapolis
From New York to San Diego bus From New York to San Diego bus
Bus from Dallas to San Diego Bus from Dallas to San Diego
Buses to San Diego from Fresno, CA Buses to San Diego from Fresno, CA
Bus Los Angeles - San Diego Bus Los Angeles - San Diego
Popular Airport Shuttles to Indianapolis and to San Diego
CheckMyBus › Buses in USA › Bus to Indianapolis › Bus to San Diego

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