Compare all timetables for the bus from Madrid to Santander
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 45m | 10:30 AM | Madrid | Avenida de América Bus Station | 4:15 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/7/2026 10:30:00 AM to Bus Station, Santander (Spain) arriving at 5/7/2026 4:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 1:00 PM | Madrid | Avenida de América Bus Station | 6:30 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/7/2026 1:00:00 PM to Bus Station, Santander (Spain) arriving at 5/7/2026 6:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 30m | 3:00 PM | Madrid | Avenida de América Bus Station | 8:30 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/7/2026 3:00:00 PM to Bus Station, Santander (Spain) arriving at 5/7/2026 8:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 30m | 6:30 PM | Madrid | Avenida de América Bus Station | 12:00 AM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/7/2026 6:30:00 PM to Bus Station, Santander (Spain) arriving at 5/8/2026 12:00:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 45m | 4:30 PM | Madrid | Avenida de América Bus Station | 10:15 PM | Santander | Bus Station | Economy | $64 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/7/2026 4:30:00 PM to Bus Station, Santander (Spain) arriving at 5/7/2026 10:15:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 5h 45m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station1:15 PMBurgosBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/9/2026 10:30:00 AM to Bus Station, Burgos (Spain) arriving at 5/9/2026 1:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 2h 45m
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ALSA2h 45m01:30 PMBurgosBus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Bus Station, Burgos (Spain) at 5/9/2026 1:30:00 PM to Bus Station, Santander (Spain) arriving at 5/9/2026 4:15:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 45m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 8:00 AM | Madrid | Avenida de América Bus Station | 1:50 PM | Santander | Bus Station | Economy | $46 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/8/2026 8:00:00 AM to Bus Station, Santander (Spain) arriving at 5/8/2026 1:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 10:30 AM | Madrid | Avenida de América Bus Station | 4:15 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/8/2026 10:30:00 AM to Bus Station, Santander (Spain) arriving at 5/8/2026 4:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 1:00 PM | Madrid | Avenida de América Bus Station | 6:30 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/8/2026 1:00:00 PM to Bus Station, Santander (Spain) arriving at 5/8/2026 6:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 45m | 4:30 PM | Madrid | Avenida de América Bus Station | 10:15 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/8/2026 4:30:00 PM to Bus Station, Santander (Spain) arriving at 5/8/2026 10:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 6:30 PM | Madrid | Avenida de América Bus Station | 12:00 AM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/8/2026 6:30:00 PM to Bus Station, Santander (Spain) arriving at 5/9/2026 12:00:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station1:15 PMBurgosBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/9/2026 10:30:00 AM to Bus Station, Burgos (Spain) arriving at 5/9/2026 1:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 2h 45m
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ALSA2h 45m01:30 PMBurgosBus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Bus Station, Burgos (Spain) at 5/9/2026 1:30:00 PM to Bus Station, Santander (Spain) arriving at 5/9/2026 4:15:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 45m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 8:00 AM | Madrid | Avenida de América Bus Station | 1:50 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/9/2026 8:00:00 AM to Bus Station, Santander (Spain) arriving at 5/9/2026 1:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 10:30 AM | Madrid | Avenida de América Bus Station | 4:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/9/2026 10:30:00 AM to Bus Station, Santander (Spain) arriving at 5/9/2026 4:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 45m | 4:30 PM | Madrid | Avenida de América Bus Station | 10:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/9/2026 4:30:00 PM to Bus Station, Santander (Spain) arriving at 5/9/2026 10:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| FlixBus | 16h 40m | 4:40 PM | Madrid | Sur Bus Station | 9:20 AM | Santander | Bus Station | Economy | $55 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 5/9/2026 4:40:00 PM to Bus Station, Santander (Spain) arriving at 5/10/2026 9:20:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 8:00 AM | Madrid | Avenida de América Bus Station | 1:50 PM | Santander | Bus Station | Economy | $46 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/10/2026 8:00:00 AM to Bus Station, Santander (Spain) arriving at 5/10/2026 1:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 10:30 AM | Madrid | Avenida de América Bus Station | 4:15 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/10/2026 10:30:00 AM to Bus Station, Santander (Spain) arriving at 5/10/2026 4:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 1:00 PM | Madrid | Avenida de América Bus Station | 6:30 PM | Santander | Bus Station | Economy | $48 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/10/2026 1:00:00 PM to Bus Station, Santander (Spain) arriving at 5/10/2026 6:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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| ALSA | 6h 0m | 12:30 AM | Madrid | Avenida de América Bus Station | 6:30 AM | Santander | Bus Station | Economy | $65 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/10/2026 12:30:00 AM to Bus Station, Santander (Spain) arriving at 5/10/2026 6:30:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 6h 0m
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| ALSA | 5h 30m | 3:00 PM | Madrid | Avenida de América Bus Station | 8:30 PM | Santander | Bus Station | Economy | $67 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/10/2026 3:00:00 PM to Bus Station, Santander (Spain) arriving at 5/10/2026 8:30:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 5h 30m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station1:15 PMBurgosBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/9/2026 10:30:00 AM to Bus Station, Burgos (Spain) arriving at 5/9/2026 1:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 2h 45m
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ALSA2h 45m01:30 PMBurgosBus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Bus Station, Burgos (Spain) at 5/9/2026 1:30:00 PM to Bus Station, Santander (Spain) arriving at 5/9/2026 4:15:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 45m
Waiting Time 0h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 45m | 10:30 AM | Madrid | Avenida de América Bus Station | 4:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/11/2026 10:30:00 AM to Bus Station, Santander (Spain) arriving at 5/11/2026 4:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 45m | 4:30 PM | Madrid | Avenida de América Bus Station | 10:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/11/2026 4:30:00 PM to Bus Station, Santander (Spain) arriving at 5/11/2026 10:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 50m | 8:00 AM | Madrid | Avenida de América Bus Station | 1:50 PM | Santander | Bus Station | Economy | $46 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/11/2026 8:00:00 AM to Bus Station, Santander (Spain) arriving at 5/11/2026 1:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 50m
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| FlixBus | 16h 40m | 4:40 PM | Madrid | Sur Bus Station | 9:20 AM | Santander | Bus Station | Economy | $53 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 5/11/2026 4:40:00 PM to Bus Station, Santander (Spain) arriving at 5/12/2026 9:20:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 45m | 10:30 AM | Madrid | Avenida de América Bus Station | 4:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/12/2026 10:30:00 AM to Bus Station, Santander (Spain) arriving at 5/12/2026 4:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 1:00 PM | Madrid | Avenida de América Bus Station | 6:30 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/12/2026 1:00:00 PM to Bus Station, Santander (Spain) arriving at 5/12/2026 6:30:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 45m | 4:30 PM | Madrid | Avenida de América Bus Station | 10:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/12/2026 4:30:00 PM to Bus Station, Santander (Spain) arriving at 5/12/2026 10:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 3:00 PM | Madrid | Avenida de América Bus Station | 8:30 PM | Santander | Bus Station | Economy | $45 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/12/2026 3:00:00 PM to Bus Station, Santander (Spain) arriving at 5/12/2026 8:30:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 50m | 8:00 AM | Madrid | Avenida de América Bus Station | 1:50 PM | Santander | Bus Station | Economy | $46 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/12/2026 8:00:00 AM to Bus Station, Santander (Spain) arriving at 5/12/2026 1:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 45m | 10:30 AM | Madrid | Avenida de América Bus Station | 4:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/13/2026 10:30:00 AM to Bus Station, Santander (Spain) arriving at 5/13/2026 4:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 1:00 PM | Madrid | Avenida de América Bus Station | 6:30 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/13/2026 1:00:00 PM to Bus Station, Santander (Spain) arriving at 5/13/2026 6:30:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 45m | 4:30 PM | Madrid | Avenida de América Bus Station | 10:15 PM | Santander | Bus Station | Economy | $43 |
A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 5/13/2026 4:30:00 PM to Bus Station, Santander (Spain) arriving at 5/13/2026 10:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 45m
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| FlixBus | 16h 40m | 4:40 PM | Madrid | Sur Bus Station | 9:20 AM | Santander | Bus Station | Economy | $51 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 5/13/2026 4:40:00 PM to Bus Station, Santander (Spain) arriving at 5/14/2026 9:20:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 16h 40m
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Best Price Offer: The price for the cheapest bus from Madrid to Santander is $39 on 5/20/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Madrid and Santander
Facts about the bus from Madrid to Santander
Compare all providers like ALSA and FlixBus that travel 16 times every day by bus from Madrid to Santander in one click! Book your bus ticket from Madrid to Santander starting from $39!
| Cheapest Bus | $39 |
| Fastest Bus | 5h 30m |
| Earliest Bus | 10:30 AM |
| Latest Bus | 6:30 PM |
| Daily Bus Routes | 16 Ø |
| Distance | 210.6 miles |
| Bus Companies | ALSA and FlixBus |
Cheapest bus connections from Madrid to Santander
Every day, 16 buses from 2 bus companies leave Madrid for Santander: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.
The cheapest time to travel from Madrid to Santander
How to save money travelling from Madrid to Santander
Book the ticket from Madrid to Santander in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Santander, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Santander are also emptier.Beloved bus companies from Madrid to Santander
ALSA from Madrid to Santander
Here you will find the key facts about the ALSA bus route Madrid to Santander:
| Cheapest Price | $43 |
| Fastest Bus | 5h 30m |
| Earliest Bus | 10:30 AM |
| Last Bus | 6:30 PM |
| Daily Connections | 15 Ø |
| Found on | 5/7/2026 |
All bus stations and stops in Madrid and Santander
In the map below, you can see where to find all bus stations in Madrid and Santander.
Service and Comfort on the bus from Madrid to Santander
FAQs about the Madrid to Santander bus
How much does a Madrid Santander bus trip cost?
How much could I save by comparing buses from Madrid to Santander?
On average, how many connections are available from Madrid to Santander each day?
How long does a bus journey from Madrid to Santander take?
What time is the first bus from Madrid to Santander?
What time is the last bus from Madrid to Santander?
Which bus companies operate the Madrid Santander route?
Is there a direct bus between Madrid and Santander?
What can I take with me on the Madrid to Santander bus route?
What equipment is available for the Madrid Santander bus route?
How does CheckMyBus find the best bus deals from Madrid to Santander?
How does CheckMyBus technology work for trips from Madrid to Santander?
Available seat classes which are offered on the bus route Madrid to Santander
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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