Compare all timetables for the bus from Madrid to Santander
Cheapest bus trips today
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ALSA5h 50m08:00 AMMadridAvenida de América Bus Station1:50 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/22/2025 8:00:00 AM to Bus Station, Santander (Spain) arriving at 6/22/2025 1:50:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 50m
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ALSA5h 30m06:30 PMMadridAvenida de América Bus Station12:00 AMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/22/2025 6:30:00 PM to Bus Station, Santander (Spain) arriving at 6/23/2025 12:00:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 30m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/22/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/22/2025 4:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 45m
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ALSA5h 45m04:30 PMMadridAvenida de América Bus Station10:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/22/2025 4:30:00 PM to Bus Station, Santander (Spain) arriving at 6/22/2025 10:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 45m
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ALSA5h 30m011:30 PMMadridAvenida de América Bus Station5:00 AMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/22/2025 11:30:00 PM to Bus Station, Santander (Spain) arriving at 6/23/2025 5:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
Cheapest bus trips tomorrow
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ALSA5h 50m08:00 AMMadridAvenida de Aragon1:50 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 6/23/2025 8:00:00 AM to Bus Station, Santander (Spain) arriving at 6/23/2025 1:50:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30 AMMadridAvenida de Aragon4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 6/23/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/23/2025 4:15:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 45m
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ALSA5h 45m04:30 PMMadridAvenida de Aragon10:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 6/23/2025 4:30:00 PM to Bus Station, Santander (Spain) arriving at 6/23/2025 10:15:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m04:40 PMMadridSur Bus Station9:20 AMSantanderBus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 6/23/2025 4:40:00 PM to Bus Station, Santander (Spain) arriving at 6/24/2025 9:20:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 16h 40m
Cheapest bus trips Tuesday
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ALSA5h 50m08:00 AMMadridAvenida de América Bus Station1:50 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/24/2025 8:00:00 AM to Bus Station, Santander (Spain) arriving at 6/24/2025 1:50:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/24/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/24/2025 4:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 45m
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ALSA5h 30m01:00 PMMadridAvenida de América Bus Station6:30 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/24/2025 1:00:00 PM to Bus Station, Santander (Spain) arriving at 6/24/2025 6:30:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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FlixBus16h 40m04:40 PMMadridSur Bus Station9:20 AMSantanderBus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 6/24/2025 4:40:00 PM to Bus Station, Santander (Spain) arriving at 6/25/2025 9:20:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 16h 40m
Cheapest bus trips Wednesday
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ALSA5h 50m08:00 AMMadridAvenida de América Bus Station1:50 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/25/2025 8:00:00 AM to Bus Station, Santander (Spain) arriving at 6/25/2025 1:50:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/25/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/25/2025 4:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 45m
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ALSA5h 50m08:00 AMMadridAvenida de Aragon1:50 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 6/25/2025 8:00:00 AM to Bus Station, Santander (Spain) arriving at 6/25/2025 1:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30 AMMadridAvenida de Aragon4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 6/25/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/25/2025 4:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 45m
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ALSA5h 30m01:00 PMMadridAvenida de América Bus Station6:30 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/25/2025 1:00:00 PM to Bus Station, Santander (Spain) arriving at 6/25/2025 6:30:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
Cheapest bus trips Thursday
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ALSA8h 0m01:15 PMMadridIntercambiador de Moncloa9:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Intercambiador de Moncloa, Madrid (Spain) at 6/26/2025 1:15:00 PM to Bus Station, Santander (Spain) arriving at 6/26/2025 9:15:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 0m
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ALSA5h 50m08:00 AMMadridAvenida de América Bus Station1:50 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/26/2025 8:00:00 AM to Bus Station, Santander (Spain) arriving at 6/26/2025 1:50:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/26/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/26/2025 4:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m04:40 PMMadridSur Bus Station9:20 AMSantanderBus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 6/26/2025 4:40:00 PM to Bus Station, Santander (Spain) arriving at 6/27/2025 9:20:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 16h 40m
Cheapest bus trips Friday
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ALSA8h 0m01:15 PMMadridIntercambiador de Moncloa9:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Intercambiador de Moncloa, Madrid (Spain) at 6/27/2025 1:15:00 PM to Bus Station, Santander (Spain) arriving at 6/27/2025 9:15:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 0m
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ALSA5h 50m08:00 AMMadridAvenida de América Bus Station1:50 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/27/2025 8:00:00 AM to Bus Station, Santander (Spain) arriving at 6/27/2025 1:50:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/27/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/27/2025 4:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m04:40 PMMadridSur Bus Station9:20 AMSantanderBus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 6/27/2025 4:40:00 PM to Bus Station, Santander (Spain) arriving at 6/28/2025 9:20:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 16h 40m
Cheapest bus trips Saturday
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ALSA8h 0m01:15 PMMadridIntercambiador de Moncloa9:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Intercambiador de Moncloa, Madrid (Spain) at 6/28/2025 1:15:00 PM to Bus Station, Santander (Spain) arriving at 6/28/2025 9:15:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 0m
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ALSA5h 45m010:30 AMMadridAvenida de América Bus Station4:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/28/2025 10:30:00 AM to Bus Station, Santander (Spain) arriving at 6/28/2025 4:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 45m
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ALSA5h 45m04:30 PMMadridAvenida de América Bus Station10:15 PMSantanderBus Station0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 6/28/2025 4:30:00 PM to Bus Station, Santander (Spain) arriving at 6/28/2025 10:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m04:40 PMMadridSur Bus Station9:20 AMSantanderBus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 6/28/2025 4:40:00 PM to Bus Station, Santander (Spain) arriving at 6/29/2025 9:20:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 16h 40m
Frequency of bus connections between Madrid and Santander
Facts about the bus from Madrid to Santander
Compare all providers like ALSA and FlixBus that travel 18 times every day by bus from Madrid to Santander in one click! Book your bus ticket from Madrid to Santander starting from $31!
Cheapest Bus | $31 |
Fastest Bus | 5h 30m |
Earliest Bus | 12:30 AM |
Latest Bus | 6:30 PM |
Daily Bus Routes | 18 Ø |
Distance | 210.6 miles |
Bus Companies | ALSA and FlixBus |
Cheapest bus connections from Madrid to Santander
Every day, 18 buses from 2 bus companies leave Madrid for Santander: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2025 and for the following days.
The cheapest time to travel from Madrid to Santander
How to save money travelling from Madrid to Santander
Book the ticket from Madrid to Santander in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Santander, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Santander are also emptier.All bus stations and stops in Madrid and Santander
In the map below, you can see where to find all bus stations in Madrid and Santander.
Compare the bus with other modes of transport
Service and Comfort on the bus from Madrid to Santander
FAQs about the Madrid to Santander bus
How much does a Madrid Santander bus trip cost?
How much could I save by comparing buses from Madrid to Santander?
On average, how many connections are available from Madrid to Santander each day?
How long does a bus journey from Madrid to Santander take?
What time is the first bus from Madrid to Santander?
What time is the last bus from Madrid to Santander?
Which bus companies operate the Madrid Santander route?
Is there a direct bus between Madrid and Santander?
What can I take with me on the Madrid to Santander bus route?
What equipment is available for the Madrid Santander bus route?
Available seat classes which are offered on the bus route Madrid to Santander
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Madrid and to Santander
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