Bus Mesa, AZ to St. Louis, MO: Compare prices and save money

Compare all timetables for the bus from Mesa, AZ to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to St. Louis, MO from various bus operators like Greyhound US for the next days.

today

tomorrow

from $182

Sunday

Monday

Tuesday

from $117

Wednesday

Thursday

from $187

Cheapest bus trips tomorrow

Prices are for one way and one person

Greyhound US

38h 30m

0

7:40 AM

Mesa, AZ
Greyhound

10:10 PM

St. Louis, MO
Gateway Station

0

Economy

$182

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/24/2025 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 5/25/2025 10:10:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 38h 30m
Greyhound US

39h 0m

0

7:40 AM

Mesa, AZ
Greyhound

10:40 PM

St. Louis, MO
Gateway Station

0

Economy

$182

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/24/2025 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 5/25/2025 10:40:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 39h 0m
Greyhound US

34h 55m

0

8:10 PM

Mesa, AZ
Greyhound

7:05 AM

St. Louis, MO
Gateway Station

0

Economy

$183

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/24/2025 8:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 5/26/2025 7:05:00 AM. 50 Economy ticket for $183 per person are available. Travel duration is 34h 55m
Greyhound US

50h 0m

0

8:10 PM

Mesa, AZ
Greyhound

10:10 PM

St. Louis, MO
Gateway Station

0

Economy

$185

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/24/2025 8:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 5/26/2025 10:10:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 50h 0m

Cheapest bus trips Tuesday

Prices are for one way and one person

Greyhound US

34h 55m

0

8:10 PM

Mesa, AZ
Greyhound

7:05 AM

St. Louis, MO
Gateway Station

0

Economy

$117

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/27/2025 8:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 5/29/2025 7:05:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 34h 55m
Greyhound US

39h 0m

0

7:40 AM

Mesa, AZ
Greyhound

10:40 PM

St. Louis, MO
Gateway Station

0

Economy

$123

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/27/2025 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 5/28/2025 10:40:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 39h 0m
Greyhound US

38h 30m

0

7:40 AM

Mesa, AZ
Greyhound

10:10 PM

St. Louis, MO
Gateway Station

0

Economy

$123

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/27/2025 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 5/28/2025 10:10:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 38h 30m
Greyhound US

34h 55m

0

8:10 PM

Mesa, AZ
Greyhound

7:05 AM

St. Louis, MO
Gateway Station

0

Economy

$125

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/27/2025 8:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 5/29/2025 7:05:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 34h 55m
Greyhound US

39h 0m

0

7:40 AM

Mesa, AZ
Greyhound

10:40 PM

St. Louis, MO
Gateway Station

0

Economy

$127

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/27/2025 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 5/28/2025 10:40:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 39h 0m

Cheapest bus trips Thursday

Prices are for one way and one person

Greyhound US

34h 55m

0

8:10 PM

Mesa, AZ
Greyhound

7:05 AM

St. Louis, MO
Gateway Station

0

Economy

$187

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/29/2025 8:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 5/31/2025 7:05:00 AM. 50 Economy ticket for $187 per person are available. Travel duration is 34h 55m
Greyhound US

39h 0m

0

7:40 AM

Mesa, AZ
Greyhound

10:40 PM

St. Louis, MO
Gateway Station

0

Economy

$191

A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 5/29/2025 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 5/30/2025 10:40:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 39h 0m

Frequency of bus connections between Mesa, AZ and St. Louis, MO

See here how frequent the connections between Mesa, AZ and St. Louis, MO are, during different times and days of the week.

Tuesday is the busiest day, with more than 5 daily buses from Mesa, AZ to St. Louis, MO. Thursday has instead the fewest connections, with only 2 daily coaches between Mesa, AZ and St. Louis, MO.

The busiest time of the day is the Morning, with 6 buses from Mesa, AZ to St. Louis, MO, while Evening sees the fewest connections between Mesa, AZ and St. Louis, MO, with 5 offers.

Facts about the bus from Mesa, AZ to St. Louis, MO

Compare all providers like Greyhound US that travel 3 times every day by bus from Mesa, AZ to St. Louis, MO in one click! Book your bus ticket from Mesa, AZ to St. Louis, MO starting from $117!

Cheapest Bus	$117
Fastest Bus	34h 55m
Earliest Bus	7:40 AM
Latest Bus	8:10 PM
Daily Bus Routes	3 Ø
Distance	1,258.1 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mesa, AZ to St. Louis, MO

Every day, 3 buses from 1 bus companies leave Mesa, AZ for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/23/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/18

Monday 05/19

Tuesday 05/20

Wednesday 05/21

Thursday 05/22

Friday 05/23

Saturday 05/24

$182

Sunday 05/25

Monday 05/26

Tuesday 05/27

$117

Wednesday 05/28

Thursday 05/29

$187

Friday 05/30

$210

Saturday 05/31

$177

Sunday 06/01

Monday 06/02

Tuesday 06/03

Wednesday 06/04

Thursday 06/05

Friday 06/06

Saturday 06/07

Sunday 06/08

Monday 06/09

Tuesday 06/10

Wednesday 06/11

Thursday 06/12

Friday 06/13

Saturday 06/14

The cheapest time to travel from Mesa, AZ to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Mesa, AZ to St. Louis, MO, for the next 30 days.

With a price starting from $117, Tuesday is the cheapest day for a bus from Mesa, AZ to St. Louis, MO. Thursday instead is the most expensive day with prices starting from $187.

Evening is the cheapest day time for bus tickets from Mesa, AZ to St. Louis, MO, with $117. Morning is the most expensive time of the day with prices starting from $123.

How to save money travelling from Mesa, AZ to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to St. Louis, MO are also emptier.

Beloved bus companies from Mesa, AZ to St. Louis, MO

These are the most booked bus companies between Mesa, AZ to St. Louis, MO from our users.

Greyhound US from Mesa, AZ to St. Louis, MO

Here you will find the key facts about the Greyhound US bus route Mesa, AZ to St. Louis, MO:

Cheapest Price	$117
Fastest Bus	34h 55m
Earliest Bus	7:40 AM
Last Bus	8:10 PM
Daily Connections	3 Ø
Found on	5/20/2025

All bus stations and stops in Mesa, AZ and St. Louis, MO

In the map below, you can see where to find all bus stations in Mesa, AZ and St. Louis, MO.

Greyhound

S Country Club Dr 1423

Fry’s Fuel Center

W Main Street 1235

Lindbergh @ Hackberry NB Bus Stop

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Gateway Station

S 15th St 430

Service and Comfort on the bus from Mesa, AZ to St. Louis, MO

Want to know which seat classes are available on the buses from Mesa, AZ to St. Louis, MO? Or which bus companies serve the route Mesa, AZ to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Mesa, AZ to St. Louis, MO bus

How much does a Mesa, AZ St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $117 and takes 34h 55m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $117 and $191. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Mesa, AZ to St. Louis, MO each day?

Every day, the Mesa, AZ to St. Louis, MO bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to St. Louis, MO take?

The fastest bus from Mesa, AZ to St. Louis, MO is offered by Greyhound US and takes 34h 55m. Bus tickets for this connection cost $183. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Mesa, AZ starts at 7:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to St. Louis, MO?

The latest bus trip departing from Mesa, AZ for St. Louis, MO starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ St. Louis, MO route?

When traveling by bus from Mesa, AZ to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and St. Louis, MO?

You can check all the direct connections between Mesa, AZ and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Mesa, AZ to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to St. Louis, MO

Here’s an overview of the most popular bus routes to Mesa, AZ and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!