Which bus from Mesa, AZ to St. Louis, MO is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $141
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Compare all timetables for the bus from Mesa, AZ to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to St. Louis, MO from various bus operators like Greyhound US for the next days.

today
tomorrow
$158
Sunday
Monday
$141
Tuesday
Wednesday
Thursday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 42h 0m 3:50 AM Mesa, AZ Greyhound 10:50 PM St. Louis, MO Gateway Station  Economy $158
Greyhound US 33h 0m 9:10 PM Mesa, AZ Greyhound 7:10 AM St. Louis, MO Gateway Station  Economy $159
Greyhound US 37h 20m 8:40 AM Mesa, AZ Greyhound 11:00 PM St. Louis, MO Gateway Station  Economy $189

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 33h 0m 9:10 PM Mesa, AZ Greyhound 7:10 AM St. Louis, MO Gateway Station  Economy $141
Greyhound US 42h 0m 3:50 AM Mesa, AZ Greyhound 10:50 PM St. Louis, MO Gateway Station  Economy $142
Greyhound US 37h 20m 8:40 AM Mesa, AZ Greyhound 11:00 PM St. Louis, MO Gateway Station  Economy $163

Best Price Offer: The price for the cheapest bus from Mesa, AZ to St. Louis, MO is $141 on 12/8/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Mesa, AZ and St. Louis, MO

See here how frequent the connections between Mesa, AZ and St. Louis, MO are, during different times and days of the week.
Monday is the busiest day, with more than 3 daily buses from Mesa, AZ to St. Louis, MO. Monday has instead the fewest connections, with only 3 daily coaches between Mesa, AZ and St. Louis, MO.
The busiest time of the day is the Morning, with 2 buses from Mesa, AZ to St. Louis, MO, while Morning sees the fewest connections between Mesa, AZ and St. Louis, MO, with 2 offers.

Facts about the bus from Mesa, AZ to St. Louis, MO

Compare all providers like Greyhound US that travel 3 times every day by bus from Mesa, AZ to St. Louis, MO in one click! Book your bus ticket from Mesa, AZ to St. Louis, MO starting from $141!

Cheapest Bus $141
Fastest Bus 34h 0m
Earliest Bus 3:50 AM
Latest Bus 9:10 PM
Daily Bus Routes 3 Ø
Distance 1,258.1 miles
Bus Companies Greyhound US

Cheapest bus connections from Mesa, AZ to St. Louis, MO

Every day, 3 buses from 1 bus companies leave Mesa, AZ for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
Friday 12/05
Saturday 12/06
$158
Sunday 12/07
Monday 12/08
$141
Tuesday 12/09
Wednesday 12/10
Thursday 12/11
Friday 12/12
Saturday 12/13
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27

The cheapest time to travel from Mesa, AZ to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Mesa, AZ to St. Louis, MO, for the next 30 days.
With a price starting from $141, Monday is the cheapest day for a bus from Mesa, AZ to St. Louis, MO. Saturday instead is the most expensive day with prices starting from $158.
Evening is the cheapest day time for bus tickets from Mesa, AZ to St. Louis, MO, with $141. Morning is the most expensive time of the day with prices starting from $163.

How to save money travelling from Mesa, AZ to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to St. Louis, MO are also emptier.

Beloved bus companies from Mesa, AZ to St. Louis, MO

These are the most booked bus companies between Mesa, AZ to St. Louis, MO from our users.

All bus stations and stops in Mesa, AZ and St. Louis, MO

In the map below, you can see where to find all bus stations in Mesa, AZ and St. Louis, MO.

Service and Comfort on the bus from Mesa, AZ to St. Louis, MO

Want to know which seat classes are available on the buses from Mesa, AZ to St. Louis, MO? Or which bus companies serve the route Mesa, AZ to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Mesa, AZ to St. Louis, MO bus

How much does a Mesa, AZ St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $141 and takes 34h 0m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $141 and $189. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Mesa, AZ to St. Louis, MO each day?

Every day, the Mesa, AZ to St. Louis, MO bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to St. Louis, MO take?

The fastest bus from Mesa, AZ to St. Louis, MO is offered by Greyhound US and takes 34h 0m. Bus tickets for this connection cost $159. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Mesa, AZ starts at 3:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to St. Louis, MO?

The latest bus trip departing from Mesa, AZ for St. Louis, MO starts at 9:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ St. Louis, MO route?

When traveling by bus from Mesa, AZ to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and St. Louis, MO?

You can check all the direct connections between Mesa, AZ and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Mesa, AZ to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to St. Louis, MO

Here’s an overview of the most popular bus routes to Mesa, AZ and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!

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