Bus Mexico City to Guanajuato: Compare prices and save money

Compare all timetables for the bus from Mexico City to Guanajuato

Here is a selection of the cheapest bus trips from the schedule from Mexico City to Guanajuato from various bus operators like ETN Autobuses or Primera Plus for the next days.

today

$54

tomorrow

$53

Saturday

$53

Sunday

$54

Monday

$53

Tuesday

$53

Wednesday

$53

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	4h 45m	6:20 AM	Mexico City	Norte Bus Station	11:05 AM	Guanajuato	Central Bus Station	Economy	$54	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/4/2025 6:20:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/4/2025 11:05:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	8:10 AM	Mexico City	Norte Bus Station	12:55 PM	Guanajuato	Central Bus Station	Economy	$54	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/4/2025 8:10:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/4/2025 12:55:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	10:00 AM	Mexico City	Norte Bus Station	2:45 PM	Guanajuato	Central Bus Station	Economy	$54	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/4/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/4/2025 2:45:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 4h 45m
ETN Autobuses	6h 0m	6:30 AM	Mexico City	Norte Bus Station	12:30 PM	Guanajuato	Central Bus Station	Basic	$76	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/4/2025 6:30:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/4/2025 12:30:00 PM. 50 Basic ticket for $76 per person are available. Travel duration is 6h 0m
ETN Autobuses	5h 20m	9:00 AM	Mexico City	Norte Bus Station	2:20 PM	Guanajuato	Central Bus Station	Basic	$76	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/4/2025 9:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/4/2025 2:20:00 PM. 50 Basic ticket for $76 per person are available. Travel duration is 5h 20m

Did you know that if you travel from Mexico City to Guanajuato via Irapuato, you can save more than $25? You can find the corresponding connections below.
- Busbud
  
  5h 20m
  
  0
  
  5:30 AM
  
  Mexico City
  José Guadalupe López Velarde Bus Stop
  
  9:45 AM
  
  Irapuato
  Hospital Militar Regional Bus Stop
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Busbud goes from José Guadalupe López Velarde Bus Stop, Mexico City (Mexico) at 12/6/2025 5:30:00 AM to Hospital Militar Regional Bus Stop, Irapuato (Mexico) arriving at 12/6/2025 9:45:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 15m
- Primera Plus
  
  0h 50m
  
  0
  
  10:00 AM
  
  Irapuato
  Central Bus Station
  
  10:50 AM
  
  Guanajuato
  Central Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Primera Plus goes from Central Bus Station, Irapuato (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 10:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 50m
Travel time is 0h 35m longer, but you will save $25

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	4h 45m	6:20 AM	Mexico City	Norte Bus Station	11:05 AM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/5/2025 6:20:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/5/2025 11:05:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	8:10 AM	Mexico City	Norte Bus Station	12:55 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/5/2025 8:10:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/5/2025 12:55:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	10:00 AM	Mexico City	Norte Bus Station	2:45 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/5/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/5/2025 2:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
ETN Autobuses	6h 0m	6:30 AM	Mexico City	Norte Bus Station	12:30 PM	Guanajuato	Central Bus Station	Basic	$74	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/5/2025 6:30:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/5/2025 12:30:00 PM. 50 Basic ticket for $74 per person are available. Travel duration is 6h 0m
ETN Autobuses	5h 20m	9:00 AM	Mexico City	Norte Bus Station	2:20 PM	Guanajuato	Central Bus Station	Basic	$74	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/5/2025 9:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/5/2025 2:20:00 PM. 50 Basic ticket for $74 per person are available. Travel duration is 5h 20m

Did you know that if you travel from Mexico City to Guanajuato via Irapuato, you can save more than $24? You can find the corresponding connections below.
- Busbud
  
  5h 20m
  
  0
  
  5:30 AM
  
  Mexico City
  José Guadalupe López Velarde Bus Stop
  
  9:45 AM
  
  Irapuato
  Hospital Militar Regional Bus Stop
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Busbud goes from José Guadalupe López Velarde Bus Stop, Mexico City (Mexico) at 12/6/2025 5:30:00 AM to Hospital Militar Regional Bus Stop, Irapuato (Mexico) arriving at 12/6/2025 9:45:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 15m
- Primera Plus
  
  0h 50m
  
  0
  
  10:00 AM
  
  Irapuato
  Central Bus Station
  
  10:50 AM
  
  Guanajuato
  Central Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Primera Plus goes from Central Bus Station, Irapuato (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 10:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 50m
Travel time is 0h 35m longer, but you will save $24

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	4h 45m	6:20 AM	Mexico City	Norte Bus Station	11:05 AM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/6/2025 6:20:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 11:05:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	8:10 AM	Mexico City	Norte Bus Station	12:55 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/6/2025 8:10:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 12:55:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	10:00 AM	Mexico City	Norte Bus Station	2:45 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 2:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
ETN Autobuses	6h 0m	6:30 AM	Mexico City	Norte Bus Station	12:30 PM	Guanajuato	Central Bus Station	Basic	$74	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/6/2025 6:30:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 12:30:00 PM. 50 Basic ticket for $74 per person are available. Travel duration is 6h 0m
ETN Autobuses	5h 20m	9:00 AM	Mexico City	Norte Bus Station	2:20 PM	Guanajuato	Central Bus Station	Basic	$74	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/6/2025 9:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 2:20:00 PM. 50 Basic ticket for $74 per person are available. Travel duration is 5h 20m

Did you know that if you travel from Mexico City to Guanajuato via Irapuato, you can save more than $24? You can find the corresponding connections below.
- Busbud
  
  5h 20m
  
  0
  
  5:30 AM
  
  Mexico City
  José Guadalupe López Velarde Bus Stop
  
  9:45 AM
  
  Irapuato
  Hospital Militar Regional Bus Stop
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Busbud goes from José Guadalupe López Velarde Bus Stop, Mexico City (Mexico) at 12/6/2025 5:30:00 AM to Hospital Militar Regional Bus Stop, Irapuato (Mexico) arriving at 12/6/2025 9:45:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 15m
- Primera Plus
  
  0h 50m
  
  0
  
  10:00 AM
  
  Irapuato
  Central Bus Station
  
  10:50 AM
  
  Guanajuato
  Central Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Primera Plus goes from Central Bus Station, Irapuato (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 10:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 50m
Travel time is 0h 35m longer, but you will save $24

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	4h 45m	6:20 AM	Mexico City	Norte Bus Station	11:05 AM	Guanajuato	Central Bus Station	Economy	$54	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/7/2025 6:20:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/7/2025 11:05:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	8:10 AM	Mexico City	Norte Bus Station	12:55 PM	Guanajuato	Central Bus Station	Economy	$54	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/7/2025 8:10:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/7/2025 12:55:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	10:00 AM	Mexico City	Norte Bus Station	2:45 PM	Guanajuato	Central Bus Station	Economy	$54	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/7/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/7/2025 2:45:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 4h 45m
ETN Autobuses	6h 0m	6:30 AM	Mexico City	Norte Bus Station	12:30 PM	Guanajuato	Central Bus Station	Basic	$76	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/7/2025 6:30:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/7/2025 12:30:00 PM. 50 Basic ticket for $76 per person are available. Travel duration is 6h 0m
ETN Autobuses	5h 20m	9:00 AM	Mexico City	Norte Bus Station	2:20 PM	Guanajuato	Central Bus Station	Basic	$76	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/7/2025 9:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/7/2025 2:20:00 PM. 50 Basic ticket for $76 per person are available. Travel duration is 5h 20m

Did you know that if you travel from Mexico City to Guanajuato via Irapuato, you can save more than $25? You can find the corresponding connections below.
- Busbud
  
  5h 20m
  
  0
  
  5:30 AM
  
  Mexico City
  José Guadalupe López Velarde Bus Stop
  
  9:45 AM
  
  Irapuato
  Hospital Militar Regional Bus Stop
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Busbud goes from José Guadalupe López Velarde Bus Stop, Mexico City (Mexico) at 12/6/2025 5:30:00 AM to Hospital Militar Regional Bus Stop, Irapuato (Mexico) arriving at 12/6/2025 9:45:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 15m
- Primera Plus
  
  0h 50m
  
  0
  
  10:00 AM
  
  Irapuato
  Central Bus Station
  
  10:50 AM
  
  Guanajuato
  Central Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Primera Plus goes from Central Bus Station, Irapuato (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 10:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 50m
Travel time is 0h 35m longer, but you will save $25

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	4h 45m	6:20 AM	Mexico City	Norte Bus Station	11:05 AM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/8/2025 6:20:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/8/2025 11:05:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	8:10 AM	Mexico City	Norte Bus Station	12:55 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/8/2025 8:10:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/8/2025 12:55:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	10:00 AM	Mexico City	Norte Bus Station	2:45 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/8/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/8/2025 2:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
ETN Autobuses	6h 0m	6:30 AM	Mexico City	Norte Bus Station	12:30 PM	Guanajuato	Central Bus Station	Basic	$76	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/8/2025 6:30:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/8/2025 12:30:00 PM. 50 Basic ticket for $76 per person are available. Travel duration is 6h 0m
ETN Autobuses	5h 20m	9:00 AM	Mexico City	Norte Bus Station	2:20 PM	Guanajuato	Central Bus Station	Basic	$76	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/8/2025 9:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/8/2025 2:20:00 PM. 50 Basic ticket for $76 per person are available. Travel duration is 5h 20m

Did you know that if you travel from Mexico City to Guanajuato via Irapuato, you can save more than $24? You can find the corresponding connections below.
- Busbud
  
  5h 20m
  
  0
  
  5:30 AM
  
  Mexico City
  José Guadalupe López Velarde Bus Stop
  
  9:45 AM
  
  Irapuato
  Hospital Militar Regional Bus Stop
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Busbud goes from José Guadalupe López Velarde Bus Stop, Mexico City (Mexico) at 12/6/2025 5:30:00 AM to Hospital Militar Regional Bus Stop, Irapuato (Mexico) arriving at 12/6/2025 9:45:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 15m
- Primera Plus
  
  0h 50m
  
  0
  
  10:00 AM
  
  Irapuato
  Central Bus Station
  
  10:50 AM
  
  Guanajuato
  Central Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Primera Plus goes from Central Bus Station, Irapuato (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 10:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 50m
Travel time is 0h 35m longer, but you will save $24

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	4h 45m	6:20 AM	Mexico City	Norte Bus Station	11:05 AM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/9/2025 6:20:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/9/2025 11:05:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	8:10 AM	Mexico City	Norte Bus Station	12:55 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/9/2025 8:10:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/9/2025 12:55:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	10:00 AM	Mexico City	Norte Bus Station	2:45 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/9/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/9/2025 2:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
ETN Autobuses	6h 0m	6:30 AM	Mexico City	Norte Bus Station	12:30 PM	Guanajuato	Central Bus Station	Basic	$74	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/9/2025 6:30:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/9/2025 12:30:00 PM. 50 Basic ticket for $74 per person are available. Travel duration is 6h 0m
ETN Autobuses	5h 20m	9:00 AM	Mexico City	Norte Bus Station	2:20 PM	Guanajuato	Central Bus Station	Basic	$74	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/9/2025 9:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/9/2025 2:20:00 PM. 50 Basic ticket for $74 per person are available. Travel duration is 5h 20m

Did you know that if you travel from Mexico City to Guanajuato via Irapuato, you can save more than $24? You can find the corresponding connections below.
- Busbud
  
  5h 20m
  
  0
  
  5:30 AM
  
  Mexico City
  José Guadalupe López Velarde Bus Stop
  
  9:45 AM
  
  Irapuato
  Hospital Militar Regional Bus Stop
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Busbud goes from José Guadalupe López Velarde Bus Stop, Mexico City (Mexico) at 12/6/2025 5:30:00 AM to Hospital Militar Regional Bus Stop, Irapuato (Mexico) arriving at 12/6/2025 9:45:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 15m
- Primera Plus
  
  0h 50m
  
  0
  
  10:00 AM
  
  Irapuato
  Central Bus Station
  
  10:50 AM
  
  Guanajuato
  Central Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Primera Plus goes from Central Bus Station, Irapuato (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 10:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 50m
Travel time is 0h 35m longer, but you will save $24

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	4h 45m	6:20 AM	Mexico City	Norte Bus Station	11:05 AM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/10/2025 6:20:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/10/2025 11:05:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	8:10 AM	Mexico City	Norte Bus Station	12:55 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/10/2025 8:10:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/10/2025 12:55:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
Primera Plus	4h 45m	10:00 AM	Mexico City	Norte Bus Station	2:45 PM	Guanajuato	Central Bus Station	Economy	$53	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 12/10/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/10/2025 2:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 45m
ETN Autobuses	6h 0m	6:30 AM	Mexico City	Norte Bus Station	12:30 PM	Guanajuato	Central Bus Station	Premium Economy	$75	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/10/2025 6:30:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/10/2025 12:30:00 PM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 6h 0m
ETN Autobuses	5h 20m	9:00 AM	Mexico City	Norte Bus Station	2:20 PM	Guanajuato	Central Bus Station	Premium Economy	$75	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 12/10/2025 9:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/10/2025 2:20:00 PM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 5h 20m

Did you know that if you travel from Mexico City to Guanajuato via Irapuato, you can save more than $24? You can find the corresponding connections below.
- Busbud
  
  5h 20m
  
  0
  
  5:30 AM
  
  Mexico City
  José Guadalupe López Velarde Bus Stop
  
  9:45 AM
  
  Irapuato
  Hospital Militar Regional Bus Stop
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Busbud goes from José Guadalupe López Velarde Bus Stop, Mexico City (Mexico) at 12/6/2025 5:30:00 AM to Hospital Militar Regional Bus Stop, Irapuato (Mexico) arriving at 12/6/2025 9:45:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 15m
- Primera Plus
  
  0h 50m
  
  0
  
  10:00 AM
  
  Irapuato
  Central Bus Station
  
  10:50 AM
  
  Guanajuato
  Central Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Primera Plus goes from Central Bus Station, Irapuato (Mexico) at 12/6/2025 10:00:00 AM to Central Bus Station, Guanajuato (Mexico) arriving at 12/6/2025 10:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 50m
Travel time is 0h 35m longer, but you will save $24

Best Price Offer: The price for the cheapest bus from Mexico City to Guanajuato is $53 on 12/5/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Mexico City and Guanajuato

See here how frequent the connections between Mexico City and Guanajuato are, during different times and days of the week.

Sunday is the busiest day, with more than 18 daily buses from Mexico City to Guanajuato. Sunday has instead the fewest connections, with only 18 daily coaches between Mexico City and Guanajuato.

The busiest time of the day is the Morning, with 70 buses from Mexico City to Guanajuato, while Afternoon sees the fewest connections between Mexico City and Guanajuato, with 28 offers.

Facts about the bus from Mexico City to Guanajuato

Compare all providers like ETN Autobuses and Primera Plus that travel 18 times every day by bus from Mexico City to Guanajuato in one click! Book your bus ticket from Mexico City to Guanajuato starting from $53!

Cheapest Bus	$53
Fastest Bus	4h 45m
Earliest Bus	6:20 AM
Latest Bus	11:50 PM
Daily Bus Routes	18 Ø
Distance	176.1 miles
Bus Companies	ETN Autobuses and Primera Plus

Cheapest bus connections from Mexico City to Guanajuato

Every day, 18 buses from 2 bus companies leave Mexico City for Guanajuato: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

$54

Friday 12/05

$75

Saturday 12/06

$53

Sunday 12/07

$76

Monday 12/08

$76

Tuesday 12/09

$53

Wednesday 12/10

$76

Thursday 12/11

$53

Friday 12/12

$54

Saturday 12/13

$74

Sunday 12/14

$74

Monday 12/15

$75

Tuesday 12/16

$75

Wednesday 12/17

$74

Thursday 12/18

$75

Friday 12/19

$75

Saturday 12/20

$57

Sunday 12/21

$75

Monday 12/22

$75

Tuesday 12/23

$57

Wednesday 12/24

$56

Thursday 12/25

$53

Friday 12/26

$75

Saturday 12/27

The cheapest time to travel from Mexico City to Guanajuato

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to Guanajuato, for the next 30 days.

With a price starting from $53, Monday is the cheapest day for a bus from Mexico City to Guanajuato. Sunday instead is the most expensive day with prices starting from $53.

Morning is the cheapest day time for bus tickets from Mexico City to Guanajuato, with $53. Morning is the most expensive time of the day with prices starting from $53.

How to save money travelling from Mexico City to Guanajuato

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to Guanajuato in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to Guanajuato, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to Guanajuato are also emptier.

Beloved bus companies from Mexico City to Guanajuato

These are the most booked bus companies between Mexico City to Guanajuato from our users.

Primera Plus from Mexico City to Guanajuato

Here you will find the key facts about the Primera Plus bus route Mexico City to Guanajuato:

Cheapest Price	$53
Fastest Bus	4h 45m
Earliest Bus	6:20 AM
Last Bus	11:50 PM
Daily Connections	8 Ø
Found on	12/4/2025

ETN Autobuses from Mexico City to Guanajuato

Here you will find the key facts about the ETN Autobuses bus route Mexico City to Guanajuato:

Cheapest Price	$74
Fastest Bus	4h 50m
Earliest Bus	6:30 AM
Last Bus	11:45 PM
Daily Connections	10 Ø
Found on	12/4/2025

All bus stations and stops in Mexico City and Guanajuato

In the map below, you can see where to find all bus stations in Mexico City and Guanajuato.

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Terminal Antas Tla

Emiliano Zapata 97

Eje Central Bus Stop

Avenida Lázaro Cárdenas & Calle Poniente 112 Avenida Lázaro Cárdenas & Calle Poniente 112

Central Bus Station

Carretera De Cuota 450

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mexico City to Guanajuato? Compare all modes of transports from Mexico City to Guanajuato.

Service and Comfort on the bus from Mexico City to Guanajuato

Want to know which seat classes are available on the buses from Mexico City to Guanajuato? Or which bus companies serve the route Mexico City to Guanajuato? Below you will find answers to your questions.

FAQs about the Mexico City to Guanajuato bus

How much does a Mexico City Guanajuato bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $53 and takes 4h 45m to reach Guanajuato. Compare offers to save money!

How much could I save by comparing buses from Mexico City to Guanajuato?

This route is offered by 2 companies with a range of ticket prices between $53 and $77. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Guanajuato.

On average, how many connections are available from Mexico City to Guanajuato each day?

Every day, the Mexico City to Guanajuato bus route is served by approximately 18 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to Guanajuato take?

The fastest bus from Mexico City to Guanajuato is offered by Primera Plus and takes 4h 45m. Bus tickets for this connection cost $54. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to Guanajuato?

The earliest bus arriving in Guanajuato from Mexico City starts at 6:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to Guanajuato?

The latest bus trip departing from Mexico City for Guanajuato starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City Guanajuato route?

When traveling by bus from Mexico City to Guanajuato, passengers can travel with ETN Autobuses and Primera Plus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and Guanajuato?

You can check all the direct connections between Mexico City and Guanajuato by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ETN Autobuses and Primera Plus.

What can I take with me on the Mexico City to Guanajuato bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City Guanajuato bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City Guanajuato bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to Guanajuato on your planned travel date.

Available seat classes which are offered on the bus route Mexico City to Guanajuato

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Mexico City and to Guanajuato

Here’s an overview of the most popular bus routes to Mexico City and to Guanajuato. Simply click on the connection of your choice, and you will find all the details about your bus route!