Bus Rome to Lucerne: Compare prices and save money

Compare all timetables for the bus from Rome to Lucerne

Here is a selection of the cheapest bus trips from the schedule from Rome to Lucerne from various bus operators like FlixBus for the next days.

today

$94

tomorrow

Sunday

Monday

$98

Tuesday

Wednesday

$64

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 40m	11:35 PM	Rome	Anagnina Bus Station	4:15 PM	Lucerne	Bus Station Inselipark	Economy	$94	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/5/2025 11:35:00 PM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/6/2025 4:15:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 40m
FlixBus	16h 25m	11:50 PM	Rome	Tiburtina Bus Station	4:15 PM	Lucerne	Bus Station Inselipark	Economy	$95	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/5/2025 11:50:00 PM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/6/2025 4:15:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 16h 25m
FlixBus	13h 5m	8:30 AM	Rome	Tiburtina Bus Station	9:35 PM	Lucerne	Bus Station Inselipark	Economy	$98	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/5/2025 8:30:00 AM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/5/2025 9:35:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 13h 5m
FlixBus	14h 35m	1:40 AM	Rome	Tiburtina Bus Station	4:15 PM	Lucerne	Bus Station Inselipark	Economy	$99	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/5/2025 1:40:00 AM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/5/2025 4:15:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 14h 35m
FlixBus	12h 50m	10:45 PM	Rome	Tiburtina Bus Station	11:35 AM	Lucerne	West	Economy	$103	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/5/2025 10:45:00 PM to West, Lucerne (Switzerland) arriving at 12/6/2025 11:35:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 12h 50m

Did you know that if you travel from Rome to Lucerne via Florence, you can save more than $25? You can find the corresponding connections below.
- FlixBus
  
  15h 35m
  
  0
  
  8:00 PM
  
  Rome
  Tiburtina Bus Station
  
  11:35 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/6/2025 8:00:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 12/6/2025 11:35:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 3h 35m
- FlixBus
  
  11h 55m
  
  0
  
  11:40 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  11:35 AM
  
  Lucerne
  West
  
  0
  
  Economy
  
  $59
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 12/6/2025 11:40:00 PM to West, Lucerne (Switzerland) arriving at 12/7/2025 11:35:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 11h 55m
Travel time is 2h 45m longer, but you will save $25

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 30m	10:40 AM	Rome	Tiburtina Bus Station	2:10 AM	Lucerne	Bus Station Inselipark	Economy	$98	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/8/2025 10:40:00 AM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/9/2025 2:10:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 15h 30m
FlixBus	14h 35m	1:40 AM	Rome	Tiburtina Bus Station	4:15 PM	Lucerne	Bus Station Inselipark	Economy	$100	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/8/2025 1:40:00 AM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/8/2025 4:15:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 14h 35m
FlixBus	15h 15m	1:05 PM	Rome	Anagnina Bus Station	4:20 AM	Lucerne	Bus Station Inselipark	Economy	$110	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/8/2025 1:05:00 PM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/9/2025 4:20:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 15h 15m
FlixBus	15h 25m	12:55 PM	Rome	Tiburtina Bus Station	4:20 AM	Lucerne	Bus Station Inselipark	Economy	$129	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/8/2025 12:55:00 PM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/9/2025 4:20:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 15h 25m

Did you know that if you travel from Rome to Lucerne via Florence, you can save more than $29? You can find the corresponding connections below.
- FlixBus
  
  15h 35m
  
  0
  
  8:00 PM
  
  Rome
  Tiburtina Bus Station
  
  11:35 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/6/2025 8:00:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 12/6/2025 11:35:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 3h 35m
- FlixBus
  
  11h 55m
  
  0
  
  11:40 PM
  
  Florence
  Piazzale Montelungo Bus Stop
  
  11:35 AM
  
  Lucerne
  West
  
  0
  
  Economy
  
  $59
  
  A Bus from FlixBus goes from Piazzale Montelungo Bus Stop, Florence (Italy) at 12/6/2025 11:40:00 PM to West, Lucerne (Switzerland) arriving at 12/7/2025 11:35:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 11h 55m
Travel time is 1h 0m longer, but you will save $29

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 50m	10:45 PM	Rome	Tiburtina Bus Station	11:35 AM	Lucerne	West	Economy	$64	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/10/2025 10:45:00 PM to West, Lucerne (Switzerland) arriving at 12/11/2025 11:35:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 50m
FlixBus	15h 15m	1:05 PM	Rome	Anagnina Bus Station	4:20 AM	Lucerne	Bus Station Inselipark	Economy	$65	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/10/2025 1:05:00 PM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/11/2025 4:20:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 15h 15m
FlixBus	16h 40m	11:35 PM	Rome	Anagnina Bus Station	4:15 PM	Lucerne	Bus Station Inselipark	Economy	$65	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/10/2025 11:35:00 PM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/11/2025 4:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 40m
FlixBus	18h 10m	5:25 PM	Rome	Anagnina Bus Station	11:35 AM	Lucerne	West	Economy	$65	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/10/2025 5:25:00 PM to West, Lucerne (Switzerland) arriving at 12/11/2025 11:35:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 18h 10m
FlixBus	16h 25m	11:50 PM	Rome	Tiburtina Bus Station	4:15 PM	Lucerne	Bus Station Inselipark	Economy	$69	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/10/2025 11:50:00 PM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/11/2025 4:15:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 16h 25m

Did you know that if you travel from Rome to Lucerne via Florence, you can save more than $9? You can find the corresponding connections below.
- FlixBus
  
  13h 20m
  
  0
  
  8:15 AM
  
  Rome
  Tiburtina Bus Station
  
  11:30 AM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $9
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/11/2025 8:15:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 12/11/2025 11:30:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 3h 15m
- FlixBus
  
  9h 40m
  
  0
  
  11:55 AM
  
  Florence
  Villa Costanza Bus Station
  
  9:35 PM
  
  Lucerne
  Bus Station Inselipark
  
  0
  
  Economy
  
  $45
  
  A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/11/2025 11:55:00 AM to Bus Station Inselipark, Lucerne (Switzerland) arriving at 12/11/2025 9:35:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 9h 40m
Travel time is 0h 30m longer, but you will save $9

Best Price Offer: The price for the cheapest bus from Rome to Lucerne is $56 on 12/2/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Rome and Lucerne

See here how frequent the connections between Rome and Lucerne are, during different times and days of the week.

Friday is the busiest day, with more than 8 daily buses from Rome to Lucerne. Monday has instead the fewest connections, with only 4 daily coaches between Rome and Lucerne.

The busiest time of the day is the Afternoon, with 8 buses from Rome to Lucerne, while Night sees the fewest connections between Rome and Lucerne, with 2 offers.

Facts about the bus from Rome to Lucerne

Compare all providers like FlixBus that travel 6 times every day by bus from Rome to Lucerne in one click! Book your bus ticket from Rome to Lucerne starting from $56!

Cheapest Bus	$56
Fastest Bus	12h 50m
Earliest Bus	1:40 AM
Latest Bus	11:50 PM
Daily Bus Routes	6 Ø
Distance	411.3 miles
Bus Companies	FlixBus

Cheapest bus connections from Rome to Lucerne

Every day, 6 buses from 1 bus companies leave Rome for Lucerne: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$94

Saturday 12/06

Sunday 12/07

Monday 12/08

$98

Tuesday 12/09

Wednesday 12/10

$64

Thursday 12/11

Friday 12/12

Saturday 12/13

$63

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$68

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Rome to Lucerne

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Lucerne, for the next 30 days.

With a price starting from $64, Wednesday is the cheapest day for a bus from Rome to Lucerne. Monday instead is the most expensive day with prices starting from $98.

Night is the cheapest day time for bus tickets from Rome to Lucerne, with $63. Morning is the most expensive time of the day with prices starting from $82.

How to save money travelling from Rome to Lucerne

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Lucerne in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Lucerne, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Lucerne are also emptier.

All bus stations and stops in Rome and Lucerne

In the map below, you can see where to find all bus stations in Rome and Lucerne.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Bus Station Inselipark

Europaplatz / Inseliquai 1

Central Bus Station

West

Autobahnraststätte West (Richtung Luzern) 1

Central Station

Eichhof Bus Stop

Service and Comfort on the bus from Rome to Lucerne

Want to know which seat classes are available on the buses from Rome to Lucerne? Or which bus companies serve the route Rome to Lucerne? Below you will find answers to your questions.

FAQs about the Rome to Lucerne bus

How much does a Rome Lucerne bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $56 and takes 12h 50m to reach Lucerne. Compare offers to save money!

How much could I save by comparing buses from Rome to Lucerne?

This route is offered by 1 companies with a range of ticket prices between $56 and $140. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lucerne.

On average, how many connections are available from Rome to Lucerne each day?

Every day, the Rome to Lucerne bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Lucerne take?

The fastest bus from Rome to Lucerne is offered by FlixBus and takes 12h 50m. Bus tickets for this connection cost $103. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Lucerne?

The earliest bus arriving in Lucerne from Rome starts at 1:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Lucerne?

The latest bus trip departing from Rome for Lucerne starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Lucerne route?

When traveling by bus from Rome to Lucerne, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Lucerne?

You can check all the direct connections between Rome and Lucerne by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Lucerne bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Lucerne bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Lucerne bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Lucerne on your planned travel date.

Available seat classes which are offered on the bus route Rome to Lucerne

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Lucerne

Here’s an overview of the most popular bus routes to Rome and to Lucerne. Simply click on the connection of your choice, and you will find all the details about your bus route!