Bus Silver Spring, MD to Greenville, SC: Compare prices and save money

Compare all timetables for the bus from Silver Spring, MD to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Silver Spring, MD to Greenville, SC from various bus operators like Greyhound US for the next days.

today

tomorrow

$85

Friday

Saturday

Sunday

$119

Monday

Tuesday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	12h 25m	2:10 AM	Silver Spring, MD	Bus Stop	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$85	A Bus from Greyhound US goes from Bus Stop, Silver Spring, MD (USA) at 12/18/2025 2:10:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/18/2025 2:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 12h 25m
	Greyhound US	13h 30m	7:05 PM	Silver Spring, MD	Bus Stop	8:35 AM	Greenville, SC	Woodruff Rd		Economy	$90	A Bus from Greyhound US goes from Bus Stop, Silver Spring, MD (USA) at 12/18/2025 7:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/19/2025 8:35:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 13h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 25m	2:10 AM	Silver Spring, MD	Bus Stop	2:35 PM	Greenville, SC	Woodruff Rd	Economy	$119	A Bus from Greyhound US goes from Bus Stop, Silver Spring, MD (USA) at 12/21/2025 2:10:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/21/2025 2:35:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 12h 25m
Greyhound US	12h 30m	8:05 PM	Silver Spring, MD	Bus Stop	8:35 AM	Greenville, SC	Woodruff Rd	Economy	$138	A Bus from Greyhound US goes from Bus Stop, Silver Spring, MD (USA) at 12/21/2025 8:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/22/2025 8:35:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 12h 30m
Greyhound US	12h 15m	7:25 AM	Silver Spring, MD	Bus Stop	7:40 PM	Greenville, SC	Woodruff Rd	Economy	$141	A Bus from Greyhound US goes from Bus Stop, Silver Spring, MD (USA) at 12/21/2025 7:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/21/2025 7:40:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 12h 15m

Did you know that if you travel from Silver Spring, MD to Greenville, SC via Washington, DC, you can save more than $33? You will find the corresponding connections below.
- Save more than 28%
  
  10h 55m
  
  Silver Spring, MD
  
  6 mi
  
  3:40 AM
  
  Washington, DC
  Union Station
  
  2:35 PM
  
  Greenville, SC
  Woodruff Rd
  
  0 mi
  
  Economy
  
  $86
  
  A Bus from goes from Union Station, Washington, DC (USA) at 12/21/2025 3:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/21/2025 2:35:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 10h 55m
Did you know that if you travel from Silver Spring, MD to Greenville, SC via Washington, DC, you can save more than $41? You can find the corresponding connections below.
- FlixBus
  
  12h 25m
  
  0
  
  2:10 AM
  
  Silver Spring, MD
  Bus Stop
  
  2:55 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $7
  
  A Bus from FlixBus goes from Bus Stop, Silver Spring, MD (USA) at 12/18/2025 2:10:00 AM to Union Station, Washington, DC (USA) arriving at 12/18/2025 2:55:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 45m
- Busbud
  
  10h 55m
  
  0
  
  3:40 AM
  
  Washington, DC
  Union Station
  
  2:35 PM
  
  Greenville, SC
  Woodruff Rd
  
  0
  
  Economy
  
  $71
  
  A Bus from Busbud goes from Union Station, Washington, DC (USA) at 12/18/2025 3:40:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/18/2025 2:35:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 10h 55m
Travel time is 0h 10m longer, but you will save $41

Best Price Offer: The price for the cheapest bus from Silver Spring, MD to Greenville, SC is $64 on 1/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Silver Spring, MD and Greenville, SC

See here how frequent the connections between Silver Spring, MD and Greenville, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 3 daily buses from Silver Spring, MD to Greenville, SC. Thursday has instead the fewest connections, with only 2 daily coaches between Silver Spring, MD and Greenville, SC.

The busiest time of the day is the Evening, with 2 buses from Silver Spring, MD to Greenville, SC, while Morning sees the fewest connections between Silver Spring, MD and Greenville, SC, with 1 offers.

Facts about the bus from Silver Spring, MD to Greenville, SC

Compare all providers like Greyhound US that travel 2 times every day by bus from Silver Spring, MD to Greenville, SC in one click! Book your bus ticket from Silver Spring, MD to Greenville, SC starting from $64!

Cheapest Bus	$64
Fastest Bus	12h 15m
Earliest Bus	2:10 AM
Latest Bus	8:05 PM
Daily Bus Routes	2 Ø
Distance	411.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Silver Spring, MD to Greenville, SC

Every day, 2 buses from 1 bus companies leave Silver Spring, MD for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$85

Friday 12/19

Saturday 12/20

Sunday 12/21

$119

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$104

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

$94

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

$97

Friday 01/02

Saturday 01/03

$89

Sunday 01/04

Monday 01/05

Tuesday 01/06

$65

Wednesday 01/07

Thursday 01/08

$64

Friday 01/09

Saturday 01/10

The cheapest time to travel from Silver Spring, MD to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Silver Spring, MD to Greenville, SC, for the next 30 days.

With a price starting from $64, Thursday is the cheapest day for a bus from Silver Spring, MD to Greenville, SC. Sunday instead is the most expensive day with prices starting from $119.

Night is the cheapest day time for bus tickets from Silver Spring, MD to Greenville, SC, with $55. Morning is the most expensive time of the day with prices starting from $140.

How to save money travelling from Silver Spring, MD to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Silver Spring, MD to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Silver Spring, MD to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Silver Spring, MD to Greenville, SC are also emptier.

All bus stations and stops in Silver Spring, MD and Greenville, SC

In the map below, you can see where to find all bus stations in Silver Spring, MD and Greenville, SC.

Bus Stop

Fenton St 8100

Central Bus Station

Colesville Rd 8400

McDonald's

Woodruff Rd 1111

Guadalajara Supermarket

White Horse Rd 2803

Greyhound Bus Station

Hendrix Dr 9

N Church St

Woodruff Rd

Woodruff Rd 1116

Service and Comfort on the bus from Silver Spring, MD to Greenville, SC

Want to know which seat classes are available on the buses from Silver Spring, MD to Greenville, SC? Or which bus companies serve the route Silver Spring, MD to Greenville, SC? Below you will find answers to your questions.

FAQs about the Silver Spring, MD to Greenville, SC bus

How much does a Silver Spring, MD Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $64 and takes 12h 25m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Silver Spring, MD to Greenville, SC?

This route is offered by 1 companies with a range of ticket prices between $64 and $141. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Silver Spring, MD to Greenville, SC each day?

Every day, the Silver Spring, MD to Greenville, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Silver Spring, MD to Greenville, SC take?

The fastest bus from Silver Spring, MD to Greenville, SC is offered by Greyhound US and takes 12h 15m. Bus tickets for this connection cost $141. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Silver Spring, MD to Greenville, SC?

The earliest bus arriving in Greenville, SC from Silver Spring, MD starts at 2:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Silver Spring, MD to Greenville, SC?

The latest bus trip departing from Silver Spring, MD for Greenville, SC starts at 8:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Silver Spring, MD Greenville, SC route?

When traveling by bus from Silver Spring, MD to Greenville, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Silver Spring, MD and Greenville, SC?

You can check all the direct connections between Silver Spring, MD and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Silver Spring, MD to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Silver Spring, MD Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Silver Spring, MD Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Silver Spring, MD to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Silver Spring, MD to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Silver Spring, MD and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Silver Spring, MD to Greenville, SC?

Prices and availability for 2 trips between Silver Spring, MD and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Silver Spring, MD to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Silver Spring, MD and to Greenville, SC

Here’s an overview of the most popular bus routes to Silver Spring, MD and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!