Bus Siracusa to Rome: Compare prices and save money

Compare all timetables for the bus from Siracusa to Rome

Here is a selection of the cheapest bus trips from the schedule from Siracusa to Rome from various bus operators like FlixBus for the next days.

today

$60

tomorrow

Wednesday

$67

Thursday

Friday

$62

Saturday

Sunday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	18h 20m	5:20 PM	Siracusa	Corso Umberto Bus Station	11:40 AM	Rome	Anagnina Bus Station		Economy	$60	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 4/27/2026 5:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 4/28/2026 11:40:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 18h 20m
	FlixBus	13h 30m	5:20 PM	Siracusa	Corso Umberto Bus Station	6:50 AM	Rome	Tiburtina Bus Station		Economy	$63	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 4/27/2026 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/28/2026 6:50:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 13h 30m

Did you know that if you travel from Siracusa to Rome via Catania, you can save more than $17? You can find the corresponding connections below.
- Interbus
  
  13h 0m
  
  0
  
  6:45 PM
  
  Siracusa
  Scala Greca Bus Station
  
  7:47 PM
  
  Catania
  Piazza Borsellino Bus Stop
  
  0
  
  Basic
  
  $7
  
  A Bus from Interbus goes from Scala Greca Bus Station, Siracusa (Italy) at 4/28/2026 6:45:00 PM to Piazza Borsellino Bus Stop, Catania (Italy) arriving at 4/28/2026 7:47:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 1h 2m
- Itabus
  
  11h 30m
  
  0
  
  8:15 PM
  
  Catania
  Central Bus Station
  
  7:45 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $36
  
  A Bus from Itabus goes from Central Bus Station, Catania (Italy) at 4/28/2026 8:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/29/2026 7:45:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 30m
Travel Time is 0h 30m shorter, and you will save $17

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	13h 30m	5:20 PM	Siracusa	Corso Umberto Bus Station	6:50 AM	Rome	Tiburtina Bus Station		Economy	$67	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 4/29/2026 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/30/2026 6:50:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 13h 30m
	FlixBus	19h 10m	5:20 PM	Siracusa	Corso Umberto Bus Station	12:30 PM	Rome	Anagnina Bus Station		Economy	$71	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 4/29/2026 5:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 4/30/2026 12:30:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 10m

Did you know that if you travel from Siracusa to Rome via Catania, you can save more than $28? You can find the corresponding connections below.
- Interbus
  
  11h 30m
  
  0
  
  6:45 PM
  
  Siracusa
  Scala Greca Bus Station
  
  7:50 PM
  
  Catania
  Central Bus Station
  
  0
  
  Basic
  
  $7
  
  A Bus from Interbus goes from Scala Greca Bus Station, Siracusa (Italy) at 5/1/2026 6:45:00 PM to Central Bus Station, Catania (Italy) arriving at 5/1/2026 7:50:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 1h 5m
- Autoservizi Salemi
  
  10h 15m
  
  0
  
  8:00 PM
  
  Catania
  Central Bus Station
  
  6:15 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Basic
  
  $32
  
  A Bus from Autoservizi Salemi goes from Central Bus Station, Catania (Italy) at 5/1/2026 8:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 6:15:00 AM. 50 Basic ticket for $32 per person are available. Travel duration is 10h 15m
Travel Time is 2h 0m shorter, and you will save $28

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	18h 20m	5:20 PM	Siracusa	Corso Umberto Bus Station	11:40 AM	Rome	Anagnina Bus Station		Economy	$62	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 5/1/2026 5:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 5/2/2026 11:40:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 18h 20m
	FlixBus	13h 30m	5:20 PM	Siracusa	Corso Umberto Bus Station	6:50 AM	Rome	Tiburtina Bus Station		Economy	$64	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 5/1/2026 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 6:50:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 13h 30m

Did you know that if you travel from Siracusa to Rome via Catania, you can save more than $25? You can find the corresponding connections below.
- Interbus
  
  12h 47m
  
  0
  
  6:58 PM
  
  Siracusa
  Scala Greca Bus Station
  
  8:02 PM
  
  Catania
  Piazza Borsellino Bus Stop
  
  0
  
  Basic
  
  $7
  
  A Bus from Interbus goes from Scala Greca Bus Station, Siracusa (Italy) at 5/2/2026 6:58:00 PM to Piazza Borsellino Bus Stop, Catania (Italy) arriving at 5/2/2026 8:02:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 1h 4m
- Itabus
  
  11h 30m
  
  0
  
  8:15 PM
  
  Catania
  Central Bus Station
  
  7:45 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $29
  
  A Bus from Itabus goes from Central Bus Station, Catania (Italy) at 5/2/2026 8:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/3/2026 7:45:00 AM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 11h 30m
Travel Time is 0h 43m shorter, and you will save $25

Best Price Offer: The price for the cheapest bus from Siracusa to Rome is $46 on 5/16/2026. Flexible travelers save on ticket prices.

Facts about the bus from Siracusa to Rome

Compare all providers like FlixBus that travel 2 times every day by bus from Siracusa to Rome in one click! Book your bus ticket from Siracusa to Rome starting from $46!

Cheapest Bus	$46
Fastest Bus	13h 30m
Earliest Bus	5:20 PM
Latest Bus	5:20 PM
Daily Bus Routes	2 Ø
Distance	365.2 miles
Bus Companies	FlixBus

Cheapest bus connections from Siracusa to Rome

Every day, 2 buses from 1 bus companies leave Siracusa for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

$60

Tuesday 04/28

Wednesday 04/29

$67

Thursday 04/30

Friday 05/01

$62

Saturday 05/02

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$65

Saturday 05/09

$52

Sunday 05/10

Monday 05/11

$52

Tuesday 05/12

Wednesday 05/13

$48

Thursday 05/14

$50

Friday 05/15

Saturday 05/16

$46

Sunday 05/17

$64

Monday 05/18

$64

Tuesday 05/19

Wednesday 05/20

$78

Thursday 05/21

Friday 05/22

$63

Saturday 05/23

How to save money travelling from Siracusa to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Siracusa to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siracusa to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siracusa to Rome are also emptier.

All bus stations and stops in Siracusa and Rome

In the map below, you can see where to find all bus stations in Siracusa and Rome.

Corso Umberto Bus Station

Corso Umberto 196

Scala Greca Bus Station

Viale Scala Greca 246

Corso Gelone

Corso Gelone 50

Via Von Platen

Fontane Bianche

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Fori Imperiali Bus Stop

Service and Comfort on the bus from Siracusa to Rome

Want to know which seat classes are available on the buses from Siracusa to Rome? Or which bus companies serve the route Siracusa to Rome? Below you will find answers to your questions.

FAQs about the Siracusa to Rome bus

How much does a Siracusa Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $46 and takes 18h 20m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Siracusa to Rome?

This route is offered by 1 companies with a range of ticket prices between $46 and $71. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Siracusa to Rome each day?

Every day, the Siracusa to Rome bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Siracusa to Rome take?

The fastest bus from Siracusa to Rome is offered by FlixBus and takes 13h 30m. Bus tickets for this connection cost $63. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Siracusa to Rome?

The earliest bus arriving in Rome from Siracusa starts at 5:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Siracusa to Rome?

The latest bus trip departing from Siracusa for Rome starts at 5:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Siracusa Rome route?

When traveling by bus from Siracusa to Rome, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Siracusa and Rome?

You can check all the direct connections between Siracusa and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Siracusa to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Siracusa Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Siracusa Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siracusa to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Siracusa to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Siracusa and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Siracusa to Rome?

Prices and availability for 2 trips between Siracusa and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Siracusa to Rome

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Siracusa and to Rome

Here’s an overview of the most popular bus routes to Siracusa and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!