Bus St. Louis, MO to Cleveland: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Cleveland

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Cleveland from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$78

Saturday

$80

Sunday

$79

Monday

$79

Tuesday

$84

Wednesday

$78

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 15m	2:00 AM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$78	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/8/2026 2:00:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/8/2026 8:15:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 17h 15m
Greyhound US	18h 30m	8:45 AM	St. Louis, MO	Gateway Station	4:15 AM	Cleveland	Greyhound Bus Station	Economy	$78	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/8/2026 8:45:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/9/2026 4:15:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 18h 30m
Greyhound US	19h 35m	1:55 PM	St. Louis, MO	Gateway Station	10:30 AM	Cleveland	Greyhound Bus Station	Economy	$78	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/8/2026 1:55:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/9/2026 10:30:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 19h 35m
FlixBus	22h 50m	4:00 PM	St. Louis, MO	Gateway Station	3:50 PM	Cleveland	Greyhound Bus Station	Economy	$78	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/8/2026 4:00:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/9/2026 3:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 22h 50m
FlixBus	19h 45m	11:30 PM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$78	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/8/2026 11:30:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/9/2026 8:15:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 19h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 50m	4:00 PM	St. Louis, MO	Gateway Station	3:50 PM	Cleveland	Greyhound Bus Station	Economy	$80	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/9/2026 4:00:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/10/2026 3:50:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 22h 50m
Greyhound US	17h 15m	2:00 AM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$81	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/9/2026 2:00:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/9/2026 8:15:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 17h 15m
Greyhound US	18h 30m	8:45 AM	St. Louis, MO	Gateway Station	4:15 AM	Cleveland	Greyhound Bus Station	Economy	$81	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/9/2026 8:45:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/10/2026 4:15:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 18h 30m
FlixBus	19h 45m	11:30 PM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$81	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/9/2026 11:30:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/10/2026 8:15:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 19h 45m
FlixBus	21h 55m	4:00 PM	St. Louis, MO	Gateway Station	2:55 PM	Cleveland	Greyhound Bus Station	Economy	$89	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/9/2026 4:00:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/10/2026 2:55:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 21h 55m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 15m	2:00 AM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/10/2026 2:00:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/10/2026 8:15:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 15m
Greyhound US	18h 30m	8:45 AM	St. Louis, MO	Gateway Station	4:15 AM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/10/2026 8:45:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/11/2026 4:15:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 30m
Greyhound US	19h 35m	1:55 PM	St. Louis, MO	Gateway Station	10:30 AM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/10/2026 1:55:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/11/2026 10:30:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 19h 35m
FlixBus	19h 45m	11:30 PM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/10/2026 11:30:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/11/2026 8:15:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 19h 45m
FlixBus	22h 50m	4:00 PM	St. Louis, MO	Gateway Station	3:50 PM	Cleveland	Greyhound Bus Station	Economy	$80	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/10/2026 4:00:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/11/2026 3:50:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 22h 50m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 15m	2:00 AM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/11/2026 2:00:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/11/2026 8:15:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 15m
Greyhound US	18h 30m	8:45 AM	St. Louis, MO	Gateway Station	4:15 AM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/11/2026 8:45:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/12/2026 4:15:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 30m
Greyhound US	19h 35m	1:55 PM	St. Louis, MO	Gateway Station	10:30 AM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/11/2026 1:55:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/12/2026 10:30:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 19h 35m
FlixBus	22h 50m	4:00 PM	St. Louis, MO	Gateway Station	3:50 PM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/11/2026 4:00:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/12/2026 3:50:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 22h 50m
FlixBus	19h 45m	11:30 PM	St. Louis, MO	Gateway Station	8:15 PM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/11/2026 11:30:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/12/2026 8:15:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 19h 45m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 30m	11:30 PM	St. Louis, MO	Gateway Station	4:00 PM	Cleveland	Greyhound Bus Station	Economy	$84	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/12/2026 11:30:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/13/2026 4:00:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 15h 30m
Greyhound US	20h 5m	1:55 PM	St. Louis, MO	Gateway Station	11:00 AM	Cleveland	Greyhound Bus Station	Economy	$84	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/12/2026 1:55:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/13/2026 11:00:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 5m
FlixBus	15h 10m	10:00 AM	St. Louis, MO	Gateway Station	2:10 AM	Cleveland	Greyhound Bus Station	Economy	$85	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/12/2026 10:00:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/13/2026 2:10:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 15h 10m
FlixBus	21h 55m	4:00 PM	St. Louis, MO	Gateway Station	2:55 PM	Cleveland	Greyhound Bus Station	Economy	$85	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/12/2026 4:00:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/13/2026 2:55:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 21h 55m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 10m	10:00 AM	St. Louis, MO	Gateway Station	2:10 AM	Cleveland	Greyhound Bus Station	Economy	$78	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/13/2026 10:00:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/14/2026 2:10:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 15h 10m
FlixBus	15h 30m	11:30 PM	St. Louis, MO	Gateway Station	4:00 PM	Cleveland	Greyhound Bus Station	Economy	$78	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 5/13/2026 11:30:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/14/2026 4:00:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 15h 30m
Greyhound US	18h 30m	8:45 AM	St. Louis, MO	Gateway Station	4:15 AM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/13/2026 8:45:00 AM to Greyhound Bus Station, Cleveland (USA) arriving at 5/14/2026 4:15:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 30m
Greyhound US	19h 35m	1:55 PM	St. Louis, MO	Gateway Station	10:30 AM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/13/2026 1:55:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/14/2026 10:30:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 19h 35m
Greyhound US	20h 5m	1:55 PM	St. Louis, MO	Gateway Station	11:00 AM	Cleveland	Greyhound Bus Station	Economy	$79	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/13/2026 1:55:00 PM to Greyhound Bus Station, Cleveland (USA) arriving at 5/14/2026 11:00:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 20h 5m

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Cleveland is $66 on 5/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Cleveland

See here how frequent the connections between St. Louis, MO and Cleveland are, during different times and days of the week.

Sunday is the busiest day, with more than 9 daily buses from St. Louis, MO to Cleveland. Tuesday has instead the fewest connections, with only 4 daily coaches between St. Louis, MO and Cleveland.

The busiest time of the day is the Afternoon, with 20 buses from St. Louis, MO to Cleveland, while Night sees the fewest connections between St. Louis, MO and Cleveland, with 4 offers.

Facts about the bus from St. Louis, MO to Cleveland

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from St. Louis, MO to Cleveland in one click! Book your bus ticket from St. Louis, MO to Cleveland starting from $66!

Cheapest Bus	$66
Fastest Bus	16h 10m
Earliest Bus	2:00 AM
Latest Bus	11:30 PM
Daily Bus Routes	7 Ø
Distance	492.7 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from St. Louis, MO to Cleveland

Every day, 7 buses from 2 bus companies leave St. Louis, MO for Cleveland: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$78

Saturday 05/09

$80

Sunday 05/10

$79

Monday 05/11

$78

Tuesday 05/12

$84

Wednesday 05/13

$77

Thursday 05/14

$75

Friday 05/15

Saturday 05/16

$86

Sunday 05/17

$86

Monday 05/18

$75

Tuesday 05/19

$66

Wednesday 05/20

$69

Thursday 05/21

$75

Friday 05/22

Saturday 05/23

$89

Sunday 05/24

$93

Monday 05/25

$83

Tuesday 05/26

Wednesday 05/27

$80

Thursday 05/28

$82

Friday 05/29

$76

Saturday 05/30

The cheapest time to travel from St. Louis, MO to Cleveland

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Cleveland, for the next 30 days.

With a price starting from $66, Tuesday is the cheapest day for a bus from St. Louis, MO to Cleveland. Sunday instead is the most expensive day with prices starting from $79.

Night is the cheapest day time for bus tickets from St. Louis, MO to Cleveland, with $66. Morning is the most expensive time of the day with prices starting from $78.

How to save money travelling from St. Louis, MO to Cleveland

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Cleveland in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Cleveland, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Cleveland are also emptier.

All bus stations and stops in St. Louis, MO and Cleveland

In the map below, you can see where to find all bus stations in St. Louis, MO and Cleveland.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Lyndhurst

Cedar Rd 25149

Greyhound Bus Station

Chester Ave 1465

Stephanie Tubbs Jones Transit Center

E 22nd St 2115

Service and Comfort on the bus from St. Louis, MO to Cleveland

Want to know which seat classes are available on the buses from St. Louis, MO to Cleveland? Or which bus companies serve the route St. Louis, MO to Cleveland? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Cleveland bus

How much does a St. Louis, MO Cleveland bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $66 and takes 20h 35m to reach Cleveland. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Cleveland?

This route is offered by 2 companies with a range of ticket prices between $66 and $147. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Cleveland.

On average, how many connections are available from St. Louis, MO to Cleveland each day?

Every day, the St. Louis, MO to Cleveland bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Cleveland take?

The fastest bus from St. Louis, MO to Cleveland is offered by FlixBus and takes 16h 10m. Bus tickets for this connection cost $86. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Cleveland?

The earliest bus arriving in Cleveland from St. Louis, MO starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Cleveland?

The latest bus trip departing from St. Louis, MO for Cleveland starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Cleveland route?

When traveling by bus from St. Louis, MO to Cleveland, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Cleveland?

You can check all the direct connections between St. Louis, MO and Cleveland by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the St. Louis, MO to Cleveland bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Cleveland bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Cleveland bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Cleveland on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Cleveland?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between St. Louis, MO and Cleveland. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Cleveland?

Prices and availability for 7 trips between St. Louis, MO and Cleveland change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Cleveland

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Cleveland

Here’s an overview of the most popular bus routes to St. Louis, MO and to Cleveland. Simply click on the connection of your choice, and you will find all the details about your bus route!