Bus St. Louis, MO to Mesa, AZ: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Mesa, AZ

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Mesa, AZ from various bus operators like Greyhound US for the next days.

today

$117

tomorrow

$118

Wednesday

$114

Thursday

$105

Friday

Saturday

$122

Sunday

$111

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	41h 10m	4:30 PM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$117	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/27/2026 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 4/29/2026 7:40:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 41h 10m
Greyhound US	32h 20m	1:20 AM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$118	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/27/2026 1:20:00 AM to Greyhound, Mesa, AZ (USA) arriving at 4/28/2026 7:40:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 32h 20m
Greyhound US	35h 30m	8:40 AM	St. Louis, MO	Gateway Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$118	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/27/2026 8:40:00 AM to Greyhound, Mesa, AZ (USA) arriving at 4/28/2026 6:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 35h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 20m	1:20 AM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$118	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/28/2026 1:20:00 AM to Greyhound, Mesa, AZ (USA) arriving at 4/29/2026 7:40:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 32h 20m
Greyhound US	35h 30m	8:40 AM	St. Louis, MO	Gateway Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$118	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/28/2026 8:40:00 AM to Greyhound, Mesa, AZ (USA) arriving at 4/29/2026 6:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 35h 30m
Greyhound US	41h 10m	4:30 PM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$120	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/28/2026 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 4/30/2026 7:40:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 41h 10m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 20m	1:20 AM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$114	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/29/2026 1:20:00 AM to Greyhound, Mesa, AZ (USA) arriving at 4/30/2026 7:40:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 32h 20m
Greyhound US	35h 30m	8:40 AM	St. Louis, MO	Gateway Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$114	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/29/2026 8:40:00 AM to Greyhound, Mesa, AZ (USA) arriving at 4/30/2026 6:10:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 35h 30m
Greyhound US	41h 10m	4:30 PM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$115	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/29/2026 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/1/2026 7:40:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 41h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 20m	1:20 AM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$105	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/30/2026 1:20:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/1/2026 7:40:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 32h 20m
Greyhound US	35h 30m	8:40 AM	St. Louis, MO	Gateway Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$105	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/30/2026 8:40:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/1/2026 6:10:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 35h 30m
Greyhound US	41h 10m	4:30 PM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$106	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/30/2026 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/2/2026 7:40:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 41h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 20m	1:20 AM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$122	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/2/2026 1:20:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/3/2026 7:40:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 32h 20m
Greyhound US	35h 30m	8:40 AM	St. Louis, MO	Gateway Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$122	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/2/2026 8:40:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/3/2026 6:10:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 35h 30m
Greyhound US	41h 10m	4:30 PM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$124	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/2/2026 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/4/2026 7:40:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 41h 10m

Did you know that if you travel from St. Louis, MO to Mesa, AZ via Phoenix, AZ, you can save more than $13? You can find the corresponding connections below.
- Greyhound US
  
  32h 20m
  
  0
  
  1:20 AM
  
  St. Louis, MO
  Gateway Station
  
  6:10 AM
  
  Phoenix, AZ
  Bus Station
  
  0
  
  Economy
  
  $106
  
  A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/28/2026 1:20:00 AM to Bus Station, Phoenix, AZ (USA) arriving at 4/29/2026 6:10:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 30h 50m
- Greyhound US
  
  0h 30m
  
  0
  
  7:10 AM
  
  Phoenix, AZ
  Bus Station
  
  7:40 AM
  
  Mesa, AZ
  Greyhound
  
  0
  
  Economy
  
  $3
  
  A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/29/2026 7:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 4/29/2026 7:40:00 AM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 30m
Travel time is 2h 0m longer, but you will save $13

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 20m	1:20 AM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$111	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/3/2026 1:20:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/4/2026 7:40:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 32h 20m
Greyhound US	35h 30m	8:40 AM	St. Louis, MO	Gateway Station	6:10 PM	Mesa, AZ	Greyhound	Economy	$111	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/3/2026 8:40:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/4/2026 6:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 35h 30m
Greyhound US	41h 10m	4:30 PM	St. Louis, MO	Gateway Station	7:40 AM	Mesa, AZ	Greyhound	Economy	$112	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/3/2026 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/5/2026 7:40:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 41h 10m

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Mesa, AZ is $105 on 4/30/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Mesa, AZ

See here how frequent the connections between St. Louis, MO and Mesa, AZ are, during different times and days of the week.

Tuesday is the busiest day, with more than 6 daily buses from St. Louis, MO to Mesa, AZ. Sunday has instead the fewest connections, with only 3 daily coaches between St. Louis, MO and Mesa, AZ.

The busiest time of the day is the Morning, with 9 buses from St. Louis, MO to Mesa, AZ, while Morning sees the fewest connections between St. Louis, MO and Mesa, AZ, with 9 offers.

Facts about the bus from St. Louis, MO to Mesa, AZ

Compare all providers like Greyhound US that travel 4 times every day by bus from St. Louis, MO to Mesa, AZ in one click! Book your bus ticket from St. Louis, MO to Mesa, AZ starting from $105!

Cheapest Bus	$105
Fastest Bus	30h 20m
Earliest Bus	1:20 AM
Latest Bus	4:30 PM
Daily Bus Routes	4 Ø
Distance	1,258.1 miles
Bus Companies	Greyhound US

Cheapest bus connections from St. Louis, MO to Mesa, AZ

Every day, 4 buses from 1 bus companies leave St. Louis, MO for Mesa, AZ: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

$117

Tuesday 04/28

$122

Wednesday 04/29

$118

Thursday 04/30

$109

Friday 05/01

Saturday 05/02

$122

Sunday 05/03

$111

Monday 05/04

$110

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$115

Saturday 05/09

$114

Sunday 05/10

$108

Monday 05/11

$109

Tuesday 05/12

Wednesday 05/13

$125

Thursday 05/14

$118

Friday 05/15

$113

Saturday 05/16

$117

Sunday 05/17

$105

Monday 05/18

Tuesday 05/19

$129

Wednesday 05/20

$122

Thursday 05/21

Friday 05/22

$115

Saturday 05/23

The cheapest time to travel from St. Louis, MO to Mesa, AZ

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Mesa, AZ, for the next 30 days.

With a price starting from $105, Sunday is the cheapest day for a bus from St. Louis, MO to Mesa, AZ. Tuesday instead is the most expensive day with prices starting from $118.

Morning is the cheapest day time for bus tickets from St. Louis, MO to Mesa, AZ, with $105. Afternoon is the most expensive time of the day with prices starting from $106.

How to save money travelling from St. Louis, MO to Mesa, AZ

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Mesa, AZ in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Mesa, AZ, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Mesa, AZ are also emptier.

All bus stations and stops in St. Louis, MO and Mesa, AZ

In the map below, you can see where to find all bus stations in St. Louis, MO and Mesa, AZ.

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Gateway Station

S 15th St 430

Fry’s Fuel Center

W Main Street 1235

Greyhound

S Country Club Dr 1423

Service and Comfort on the bus from St. Louis, MO to Mesa, AZ

Want to know which seat classes are available on the buses from St. Louis, MO to Mesa, AZ? Or which bus companies serve the route St. Louis, MO to Mesa, AZ? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Mesa, AZ bus

How much does a St. Louis, MO Mesa, AZ bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $105 and takes 30h 20m to reach Mesa, AZ. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Mesa, AZ?

This route is offered by 1 companies with a range of ticket prices between $105 and $124. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mesa, AZ.

On average, how many connections are available from St. Louis, MO to Mesa, AZ each day?

Every day, the St. Louis, MO to Mesa, AZ bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Mesa, AZ take?

The fastest bus from St. Louis, MO to Mesa, AZ is offered by Greyhound US and takes 30h 20m. Bus tickets for this connection cost $118. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Mesa, AZ?

The earliest bus arriving in Mesa, AZ from St. Louis, MO starts at 1:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Mesa, AZ?

The latest bus trip departing from St. Louis, MO for Mesa, AZ starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Mesa, AZ route?

When traveling by bus from St. Louis, MO to Mesa, AZ, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Mesa, AZ?

You can check all the direct connections between St. Louis, MO and Mesa, AZ by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the St. Louis, MO to Mesa, AZ bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Mesa, AZ bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Mesa, AZ bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Mesa, AZ on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Mesa, AZ?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between St. Louis, MO and Mesa, AZ. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Mesa, AZ?

Prices and availability for 4 trips between St. Louis, MO and Mesa, AZ change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Mesa, AZ

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Mesa, AZ

Here’s an overview of the most popular bus routes to St. Louis, MO and to Mesa, AZ. Simply click on the connection of your choice, and you will find all the details about your bus route!