Bus St. Louis, MO to Mesa, AZ: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Mesa, AZ

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Mesa, AZ from various bus operators like Greyhound US for the next days.

today

tomorrow

from $176

Sunday

from $153

Monday

from $127

Tuesday

Wednesday

Thursday

from $200

Cheapest bus trips tomorrow

Prices are for one way and one person

Greyhound US

34h 35m

0

7:35 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$176

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 7:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/25/2025 6:10:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 34h 35m
Greyhound US

34h 35m

0

7:35 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$177

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 7:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/25/2025 6:10:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 34h 35m
Greyhound US

34h 5m

0

8:05 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$177

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 8:05:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/25/2025 6:10:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 34h 5m
Greyhound US

30h 5m

0

1:35 AM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$194

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 1:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/25/2025 7:40:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 30h 5m
Greyhound US

39h 10m

0

4:30 PM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$207

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/24/2025 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/26/2025 7:40:00 AM. 50 Economy ticket for $207 per person are available. Travel duration is 39h 10m

Cheapest bus trips Sunday

Prices are for one way and one person

Greyhound US

34h 35m

0

7:35 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$153

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 7:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/26/2025 6:10:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 34h 35m
Greyhound US

30h 5m

0

1:35 AM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$166

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 1:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/26/2025 7:40:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 30h 5m
Greyhound US

39h 10m

0

4:30 PM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$228

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/25/2025 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/27/2025 7:40:00 AM. 50 Economy ticket for $228 per person are available. Travel duration is 39h 10m

Cheapest bus trips Monday

Prices are for one way and one person

Greyhound US

39h 10m

0

4:30 PM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$127

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/28/2025 7:40:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 39h 10m
Greyhound US

34h 35m

0

7:35 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$128

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 7:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/27/2025 6:10:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 34h 35m
Greyhound US

34h 5m

0

8:05 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$128

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 8:05:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/27/2025 6:10:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 34h 5m
Greyhound US

30h 5m

0

1:35 AM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$162

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 1:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/27/2025 7:40:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 30h 5m

Cheapest bus trips Thursday

Prices are for one way and one person

Greyhound US

34h 35m

0

7:35 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$200

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/29/2025 7:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/30/2025 6:10:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 34h 35m
Greyhound US

34h 5m

0

8:05 AM

St. Louis, MO
Gateway Station

6:10 PM

Mesa, AZ
Greyhound

0

Economy

$200

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/29/2025 8:05:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/30/2025 6:10:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 34h 5m
Greyhound US

30h 5m

0

1:35 AM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$218

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/29/2025 1:35:00 AM to Greyhound, Mesa, AZ (USA) arriving at 5/30/2025 7:40:00 AM. 50 Economy ticket for $218 per person are available. Travel duration is 30h 5m
Greyhound US

39h 10m

0

4:30 PM

St. Louis, MO
Gateway Station

7:40 AM

Mesa, AZ
Greyhound

0

Economy

$235

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 5/29/2025 4:30:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/31/2025 7:40:00 AM. 50 Economy ticket for $235 per person are available. Travel duration is 39h 10m
Did you know that if you travel from St. Louis, MO to Mesa, AZ via El Paso, TX, you can save more than $21? You can find the corresponding connections below.
- Busbud
  
  42h 40m
  
  0
  
  8:05 AM
  
  St. Louis, MO
  Gateway Station
  
  10:30 AM
  
  El Paso, TX
  Bus Station
  
  0
  
  Economy
  
  $130
  
  A Bus from Busbud goes from Gateway Station, St. Louis, MO (USA) at 5/26/2025 8:05:00 AM to Bus Station, El Paso, TX (USA) arriving at 5/27/2025 10:30:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 26h 25m
- FlixBus
  
  9h 50m
  
  0
  
  4:55 PM
  
  El Paso, TX
  Bus Station
  
  2:45 AM
  
  Mesa, AZ
  Greyhound
  
  0
  
  Economy
  
  $48
  
  A Bus from FlixBus goes from Bus Station, El Paso, TX (USA) at 5/27/2025 4:55:00 PM to Greyhound, Mesa, AZ (USA) arriving at 5/28/2025 2:45:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 9h 50m
Travel time is 12h 35m longer, but you will save $21

Frequency of bus connections between St. Louis, MO and Mesa, AZ

See here how frequent the connections between St. Louis, MO and Mesa, AZ are, during different times and days of the week.

Saturday is the busiest day, with more than 7 daily buses from St. Louis, MO to Mesa, AZ. Sunday has instead the fewest connections, with only 3 daily coaches between St. Louis, MO and Mesa, AZ.

The busiest time of the day is the Morning, with 8 buses from St. Louis, MO to Mesa, AZ, while Afternoon sees the fewest connections between St. Louis, MO and Mesa, AZ, with 5 offers.

Facts about the bus from St. Louis, MO to Mesa, AZ

Compare all providers like Greyhound US that travel 4 times every day by bus from St. Louis, MO to Mesa, AZ in one click! Book your bus ticket from St. Louis, MO to Mesa, AZ starting from $127!

Cheapest Bus	$127
Fastest Bus	30h 5m
Earliest Bus	1:35 AM
Latest Bus	4:30 PM
Daily Bus Routes	4 Ø
Distance	1,258.1 miles
Bus Companies	Greyhound US

Cheapest bus connections from St. Louis, MO to Mesa, AZ

Every day, 4 buses from 1 bus companies leave St. Louis, MO for Mesa, AZ: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/23/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/18

Monday 05/19

Tuesday 05/20

Wednesday 05/21

Thursday 05/22

Friday 05/23

Saturday 05/24

$177

Sunday 05/25

$153

Monday 05/26

$127

Tuesday 05/27

Wednesday 05/28

Thursday 05/29

$200

Friday 05/30

$129

Saturday 05/31

$253

Sunday 06/01

Monday 06/02

Tuesday 06/03

Wednesday 06/04

Thursday 06/05

Friday 06/06

Saturday 06/07

Sunday 06/08

Monday 06/09

Tuesday 06/10

Wednesday 06/11

Thursday 06/12

Friday 06/13

Saturday 06/14

The cheapest time to travel from St. Louis, MO to Mesa, AZ

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Mesa, AZ, for the next 30 days.

With a price starting from $127, Monday is the cheapest day for a bus from St. Louis, MO to Mesa, AZ. Thursday instead is the most expensive day with prices starting from $200.

Afternoon is the cheapest day time for bus tickets from St. Louis, MO to Mesa, AZ, with $127. Night is the most expensive time of the day with prices starting from $162.

How to save money travelling from St. Louis, MO to Mesa, AZ

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Mesa, AZ in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Mesa, AZ, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Mesa, AZ are also emptier.

All bus stations and stops in St. Louis, MO and Mesa, AZ

In the map below, you can see where to find all bus stations in St. Louis, MO and Mesa, AZ.

Lindbergh @ Hackberry NB Bus Stop

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Gateway Station

S 15th St 430

Greyhound

S Country Club Dr 1423

Fry’s Fuel Center

W Main Street 1235

Service and Comfort on the bus from St. Louis, MO to Mesa, AZ

Want to know which seat classes are available on the buses from St. Louis, MO to Mesa, AZ? Or which bus companies serve the route St. Louis, MO to Mesa, AZ? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Mesa, AZ bus

How much does a St. Louis, MO Mesa, AZ bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $127 and takes 39h 10m to reach Mesa, AZ. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Mesa, AZ?

This route is offered by 1 companies with a range of ticket prices between $127 and $235. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mesa, AZ.

On average, how many connections are available from St. Louis, MO to Mesa, AZ each day?

Every day, the St. Louis, MO to Mesa, AZ bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Mesa, AZ take?

The fastest bus from St. Louis, MO to Mesa, AZ is offered by Greyhound US and takes 30h 5m. Bus tickets for this connection cost $216. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Mesa, AZ?

The earliest bus arriving in Mesa, AZ from St. Louis, MO starts at 1:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Mesa, AZ?

The latest bus trip departing from St. Louis, MO for Mesa, AZ starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Mesa, AZ route?

When traveling by bus from St. Louis, MO to Mesa, AZ, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Mesa, AZ?

You can check all the direct connections between St. Louis, MO and Mesa, AZ by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the St. Louis, MO to Mesa, AZ bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Mesa, AZ bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Mesa, AZ bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Mesa, AZ on your planned travel date.

Available seat classes which are offered on the bus route St. Louis, MO to Mesa, AZ

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Mesa, AZ

Here’s an overview of the most popular bus routes to St. Louis, MO and to Mesa, AZ. Simply click on the connection of your choice, and you will find all the details about your bus route!