Bus Cincinnati to Greenville, SC - Compare all Companies

Compare all timetables for the bus from Cincinnati to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Cincinnati to Greenville, SC from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Saturday

$86

Sunday

$83

Monday

$80

Tuesday

$85

Wednesday

$82

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 15m	12:55 AM	Cincinnati	E Galbraith Rd	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$86	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/9/2026 12:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/9/2026 4:10:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 15h 15m
Greyhound US	20h 35m	10:25 AM	Cincinnati	Downtown	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$86	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 5/9/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/10/2026 7:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 35m
FlixBus	21h 50m	2:10 PM	Cincinnati	Downtown	12:00 PM	Greenville, SC	Woodruff Rd	Economy	$86	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 5/9/2026 2:10:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/10/2026 12:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 21h 50m
FlixBus	21h 0m	3:00 PM	Cincinnati	University of Cincinnati	12:00 PM	Greenville, SC	Woodruff Rd	Economy	$86	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 5/9/2026 3:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/10/2026 12:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 21h 0m
Greyhound US	17h 5m	1:55 PM	Cincinnati	E Galbraith Rd	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$87	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/9/2026 1:55:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/10/2026 7:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 5m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 15m	12:55 AM	Cincinnati	E Galbraith Rd	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$83	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/10/2026 12:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/10/2026 4:10:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 15m
Greyhound US	21h 5m	5:30 PM	Cincinnati	E Galbraith Rd	2:35 PM	Greenville, SC	Woodruff Rd	Economy	$83	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/10/2026 5:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/11/2026 2:35:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 21h 5m
Greyhound US	20h 35m	10:25 AM	Cincinnati	Downtown	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$83	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 5/10/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/11/2026 7:00:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 20h 35m
FlixBus	20h 40m	2:00 PM	Cincinnati	Downtown	10:40 AM	Greenville, SC	Woodruff Rd	Economy	$84	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 5/10/2026 2:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/11/2026 10:40:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 40m
FlixBus	21h 0m	1:40 PM	Cincinnati	University of Cincinnati	10:40 AM	Greenville, SC	Woodruff Rd	Economy	$84	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 5/10/2026 1:40:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/11/2026 10:40:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 21h 0m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 5m	1:55 PM	Cincinnati	E Galbraith Rd	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$80	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/11/2026 1:55:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/12/2026 7:00:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 17h 5m
Greyhound US	15h 15m	12:55 AM	Cincinnati	E Galbraith Rd	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$81	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/11/2026 12:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/11/2026 4:10:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 15h 15m
Greyhound US	20h 35m	10:25 AM	Cincinnati	Downtown	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$81	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 5/11/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/12/2026 7:00:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 20h 35m
FlixBus	26h 0m	2:10 PM	Cincinnati	Downtown	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$81	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 5/11/2026 2:10:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/12/2026 4:10:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 26h 0m
FlixBus	25h 10m	3:00 PM	Cincinnati	University of Cincinnati	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$81	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 5/11/2026 3:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/12/2026 4:10:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 25h 10m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 5m	5:30 PM	Cincinnati	E Galbraith Rd	2:35 PM	Greenville, SC	Woodruff Rd	Economy	$85	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/12/2026 5:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/13/2026 2:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 21h 5m
Greyhound US	15h 15m	12:55 AM	Cincinnati	E Galbraith Rd	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$86	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/12/2026 12:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/12/2026 4:10:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 15h 15m
Greyhound US	20h 35m	10:25 AM	Cincinnati	Downtown	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$86	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 5/12/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/13/2026 7:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 35m
Greyhound US	17h 5m	1:55 PM	Cincinnati	E Galbraith Rd	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$87	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 5/12/2026 1:55:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/13/2026 7:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 5m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 5m	1:55 PM	Cincinnati	Greyhound Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$82	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 5/13/2026 1:55:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/14/2026 7:00:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 17h 5m
Greyhound US	21h 5m	5:30 PM	Cincinnati	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd	Economy	$82	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 5/13/2026 5:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/14/2026 2:35:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 21h 5m
Greyhound US	15h 15m	12:55 AM	Cincinnati	Greyhound Bus Station	4:10 PM	Greenville, SC	Woodruff Rd	Economy	$83	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 5/13/2026 12:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/13/2026 4:10:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 15m
Greyhound US	20h 35m	10:25 AM	Cincinnati	Downtown	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$83	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 5/13/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 5/14/2026 7:00:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 20h 35m

Best Price Offer: The price for the cheapest bus from Cincinnati to Greenville, SC is $74 on 5/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Cincinnati and Greenville, SC

See here how frequent the connections between Cincinnati and Greenville, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 16 daily buses from Cincinnati to Greenville, SC. Wednesday has instead the fewest connections, with only 4 daily coaches between Cincinnati and Greenville, SC.

The busiest time of the day is the Afternoon, with 30 buses from Cincinnati to Greenville, SC, while Morning sees the fewest connections between Cincinnati and Greenville, SC, with 7 offers.

Facts about the bus from Cincinnati to Greenville, SC

Compare all providers like Greyhound US and FlixBus that travel 8 times every day by bus from Cincinnati to Greenville, SC in one click! Book your bus ticket from Cincinnati to Greenville, SC starting from $74!

Cheapest Bus	$74
Fastest Bus	15h 15m
Earliest Bus	12:55 AM
Latest Bus	5:30 PM
Daily Bus Routes	8 Ø
Distance	316.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Cincinnati to Greenville, SC

Every day, 8 buses from 2 bus companies leave Cincinnati for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

$86

Sunday 05/10

$83

Monday 05/11

$80

Tuesday 05/12

$97

Wednesday 05/13

$82

Thursday 05/14

$74

Friday 05/15

$97

Saturday 05/16

$86

Sunday 05/17

$111

Monday 05/18

$78

Tuesday 05/19

$88

Wednesday 05/20

$91

Thursday 05/21

$96

Friday 05/22

$97

Saturday 05/23

$99

Sunday 05/24

$98

Monday 05/25

$96

Tuesday 05/26

Wednesday 05/27

$97

Thursday 05/28

$97

Friday 05/29

$97

Saturday 05/30

The cheapest time to travel from Cincinnati to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Cincinnati to Greenville, SC, for the next 30 days.

With a price starting from $78, Monday is the cheapest day for a bus from Cincinnati to Greenville, SC. Saturday instead is the most expensive day with prices starting from $86.

Night is the cheapest day time for bus tickets from Cincinnati to Greenville, SC, with $74. Morning is the most expensive time of the day with prices starting from $81.

How to save money travelling from Cincinnati to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cincinnati to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cincinnati to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cincinnati to Greenville, SC are also emptier.

All bus stations and stops in Cincinnati and Greenville, SC

In the map below, you can see where to find all bus stations in Cincinnati and Greenville, SC.

University of Cincinnati

Commons Way 2815

Greyhound Bus Station

Gilbert Ave 1005

E Galbraith Rd

Downtown

E Court St 419

Bus Stop

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

N Church St

Service and Comfort on the bus from Cincinnati to Greenville, SC

Want to know which seat classes are available on the buses from Cincinnati to Greenville, SC? Or which bus companies serve the route Cincinnati to Greenville, SC? Below you will find answers to your questions.

FAQs about the Cincinnati to Greenville, SC bus

How much does a Cincinnati Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 17h 5m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Cincinnati to Greenville, SC?

This route is offered by 2 companies with a range of ticket prices between $74 and $91. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Cincinnati to Greenville, SC each day?

Every day, the Cincinnati to Greenville, SC bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cincinnati to Greenville, SC take?

The fastest bus from Cincinnati to Greenville, SC is offered by Greyhound US and takes 15h 15m. Bus tickets for this connection cost $86. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cincinnati to Greenville, SC?

The earliest bus arriving in Greenville, SC from Cincinnati starts at 12:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cincinnati to Greenville, SC?

The latest bus trip departing from Cincinnati for Greenville, SC starts at 5:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cincinnati Greenville, SC route?

When traveling by bus from Cincinnati to Greenville, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cincinnati and Greenville, SC?

You can check all the direct connections between Cincinnati and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Cincinnati to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cincinnati Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cincinnati Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cincinnati to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Cincinnati to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between Cincinnati and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Cincinnati to Greenville, SC?

Prices and availability for 8 trips between Cincinnati and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Cincinnati to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cincinnati and to Greenville, SC

Here’s an overview of the most popular bus routes to Cincinnati and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!