Bus from Pittsburgh to Greenville, SC from $80

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Compare all timetables for the bus from Pittsburgh to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Pittsburgh to Greenville, SC from various bus operators like Greyhound US or FlixBus for the next days.

today
tomorrow
$116
Wednesday
Thursday
Friday
Saturday
$98
Sunday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 26h 20m 8:30 AM Pittsburgh Grant Street Transportation Center 10:50 AM Greenville, SC Woodruff Rd  Economy $116
Greyhound US 17h 35m 9:00 PM Pittsburgh Grant Street Transportation Center 2:35 PM Greenville, SC Woodruff Rd  Economy $117
Greyhound US 29h 30m 1:35 AM Pittsburgh Grant Street Transportation Center 7:05 AM Greenville, SC Woodruff Rd  Economy $119

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 17h 55m 1:30 AM Pittsburgh Grant Street Transportation Center 7:25 PM Greenville, SC Woodruff Rd  Economy $98
Greyhound US 17h 35m 9:00 PM Pittsburgh Grant Street Transportation Center 2:35 PM Greenville, SC Woodruff Rd  Economy $98
Greyhound US 29h 30m 1:35 AM Pittsburgh Grant Street Transportation Center 7:05 AM Greenville, SC Woodruff Rd  Economy $99
FlixBus 20h 50m 11:45 AM Pittsburgh Grant Street Transportation Center 8:35 AM Greenville, SC Woodruff Rd  Economy $99

Best Price Offer: The price for the cheapest bus from Pittsburgh to Greenville, SC is $80 on 2/7/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Pittsburgh and Greenville, SC

See here how frequent the connections between Pittsburgh and Greenville, SC are, during different times and days of the week.
Saturday is the busiest day, with more than 8 daily buses from Pittsburgh to Greenville, SC. Tuesday has instead the fewest connections, with only 3 daily coaches between Pittsburgh and Greenville, SC.
The busiest time of the day is the Night, with 5 buses from Pittsburgh to Greenville, SC, while Morning sees the fewest connections between Pittsburgh and Greenville, SC, with 3 offers.

Facts about the bus from Pittsburgh to Greenville, SC

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from Pittsburgh to Greenville, SC in one click! Book your bus ticket from Pittsburgh to Greenville, SC starting from $80!

Cheapest Bus $80
Fastest Bus 17h 35m
Earliest Bus 1:35 AM
Latest Bus 9:00 PM
Daily Bus Routes 5 Ø
Distance 408.1 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Pittsburgh to Greenville, SC

Every day, 5 buses from 2 bus companies leave Pittsburgh for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 01/18
Monday 01/19
Tuesday 01/20
$116
Wednesday 01/21
Thursday 01/22
Friday 01/23
Saturday 01/24
$113
Sunday 01/25
Monday 01/26
Tuesday 01/27
Wednesday 01/28
Thursday 01/29
Friday 01/30
Saturday 01/31
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$80
Sunday 02/08
Monday 02/09
Tuesday 02/10
Wednesday 02/11
Thursday 02/12
Friday 02/13
Saturday 02/14

The cheapest time to travel from Pittsburgh to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Pittsburgh to Greenville, SC, for the next 30 days.
With a price starting from $80, Saturday is the cheapest day for a bus from Pittsburgh to Greenville, SC. Tuesday instead is the most expensive day with prices starting from $116.
Night is the cheapest day time for bus tickets from Pittsburgh to Greenville, SC, with $80. Morning is the most expensive time of the day with prices starting from $99.

How to save money travelling from Pittsburgh to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pittsburgh to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pittsburgh to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Pittsburgh to Greenville, SC are also emptier.

Beloved bus companies from Pittsburgh to Greenville, SC

These are the most booked bus companies between Pittsburgh to Greenville, SC from our users.

Greyhound US from Pittsburgh to Greenville, SC

Greyhound US

Here you will find the key facts about the Greyhound US bus route Pittsburgh to Greenville, SC:

Cheapest Price $98
Fastest Bus 17h 35m
Earliest Bus 1:35 AM
Last Bus 9:00 PM
Daily Connections 4 Ø
Found on 1/16/2026

All bus stations and stops in Pittsburgh and Greenville, SC

In the map below, you can see where to find all bus stations in Pittsburgh and Greenville, SC.

Service and Comfort on the bus from Pittsburgh to Greenville, SC

Want to know which seat classes are available on the buses from Pittsburgh to Greenville, SC? Or which bus companies serve the route Pittsburgh to Greenville, SC? Below you will find answers to your questions.

FAQs about the Pittsburgh to Greenville, SC bus

How much does a Pittsburgh Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $80 and takes 17h 55m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Pittsburgh to Greenville, SC?

This route is offered by 2 companies with a range of ticket prices between $80 and $119. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Pittsburgh to Greenville, SC each day?

Every day, the Pittsburgh to Greenville, SC bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Pittsburgh to Greenville, SC take?

The fastest bus from Pittsburgh to Greenville, SC is offered by Greyhound US and takes 17h 35m. Bus tickets for this connection cost $117. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Pittsburgh to Greenville, SC?

The earliest bus arriving in Greenville, SC from Pittsburgh starts at 1:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Pittsburgh to Greenville, SC?

The latest bus trip departing from Pittsburgh for Greenville, SC starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Pittsburgh Greenville, SC route?

When traveling by bus from Pittsburgh to Greenville, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Pittsburgh and Greenville, SC?

You can check all the direct connections between Pittsburgh and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Pittsburgh to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Pittsburgh Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Pittsburgh Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pittsburgh to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Pittsburgh to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Pittsburgh and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Pittsburgh to Greenville, SC?

Prices and availability for 5 trips between Pittsburgh and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Pittsburgh to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pittsburgh and to Greenville, SC

Here’s an overview of the most popular bus routes to Pittsburgh and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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