Bus Greenville, SC to Cincinnati: Compare prices and save money

Compare all timetables for the bus from Greenville, SC to Cincinnati

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Cincinnati from various bus operators like FlixBus or Greyhound US for the next days.

today

$78

tomorrow

Saturday

$89

Sunday

$86

Monday

$86

Tuesday

Wednesday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	12h 40m	2:45 PM	Greenville, SC	Woodruff Rd	3:25 AM	Cincinnati	E Galbraith Rd		Economy	$78	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/4/2026 2:45:00 PM to E Galbraith Rd, Cincinnati (USA) arriving at 6/5/2026 3:25:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 40m	2:45 PM	Greenville, SC	Woodruff Rd	3:25 AM	Cincinnati	Greyhound Bus Station	Economy	$89	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/6/2026 2:45:00 PM to Greyhound Bus Station, Cincinnati (USA) arriving at 6/7/2026 3:25:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 12h 40m
FlixBus	24h 0m	1:20 PM	Greenville, SC	Woodruff Rd	1:20 PM	Cincinnati	University of Cincinnati	Economy	$90	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/6/2026 1:20:00 PM to University of Cincinnati, Cincinnati (USA) arriving at 6/7/2026 1:20:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 24h 0m
FlixBus	21h 35m	7:40 PM	Greenville, SC	Woodruff Rd	5:15 PM	Cincinnati	Greyhound Bus Station	Economy	$93	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/6/2026 7:40:00 PM to Greyhound Bus Station, Cincinnati (USA) arriving at 6/7/2026 5:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 21h 35m

Did you know that if you travel from Greenville, SC to Cincinnati via Lexington, KY, you can save more than $11? You can find the corresponding connections below.
- Greyhound US
  
  12h 40m
  
  0
  
  2:45 PM
  
  Greenville, SC
  Woodruff Rd
  
  1:45 AM
  
  Lexington, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $64
  
  A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/8/2026 2:45:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/9/2026 1:45:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 11h 0m
- Greyhound US
  
  1h 30m
  
  0
  
  1:55 AM
  
  Lexington, KY
  Greyhound Bus Station
  
  3:25 AM
  
  Cincinnati
  E Galbraith Rd
  
  0
  
  Economy
  
  $14
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Lexington, KY (USA) at 6/9/2026 1:55:00 AM to E Galbraith Rd, Cincinnati (USA) arriving at 6/9/2026 3:25:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 1h 30m
Travel time is the same as the direct connection, but you will save $11

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 0m	1:20 PM	Greenville, SC	Woodruff Rd	1:20 PM	Cincinnati	University of Cincinnati	Economy	$86	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/7/2026 1:20:00 PM to University of Cincinnati, Cincinnati (USA) arriving at 6/8/2026 1:20:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 24h 0m
FlixBus	21h 35m	7:40 PM	Greenville, SC	Woodruff Rd	5:15 PM	Cincinnati	E Galbraith Rd	Economy	$86	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/7/2026 7:40:00 PM to E Galbraith Rd, Cincinnati (USA) arriving at 6/8/2026 5:15:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 21h 35m
Greyhound US	12h 40m	2:45 PM	Greenville, SC	Woodruff Rd	3:25 AM	Cincinnati	E Galbraith Rd	Economy	$92	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/7/2026 2:45:00 PM to E Galbraith Rd, Cincinnati (USA) arriving at 6/8/2026 3:25:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 12h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 0m	1:20 PM	Greenville, SC	Woodruff Rd	1:20 PM	Cincinnati	University of Cincinnati	Economy	$86	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/8/2026 1:20:00 PM to University of Cincinnati, Cincinnati (USA) arriving at 6/9/2026 1:20:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 24h 0m
Greyhound US	12h 40m	2:45 PM	Greenville, SC	Woodruff Rd	3:25 AM	Cincinnati	E Galbraith Rd	Economy	$86	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/8/2026 2:45:00 PM to E Galbraith Rd, Cincinnati (USA) arriving at 6/9/2026 3:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 12h 40m
FlixBus	21h 35m	7:40 PM	Greenville, SC	Woodruff Rd	5:15 PM	Cincinnati	E Galbraith Rd	Economy	$89	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/8/2026 7:40:00 PM to E Galbraith Rd, Cincinnati (USA) arriving at 6/9/2026 5:15:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 21h 35m

Did you know that if you travel from Greenville, SC to Cincinnati via Lexington, KY, you can save more than $15? You can find the corresponding connections below.
- Greyhound US
  
  12h 40m
  
  0
  
  2:45 PM
  
  Greenville, SC
  Woodruff Rd
  
  1:45 AM
  
  Lexington, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $57
  
  A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/10/2026 2:45:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/11/2026 1:45:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 11h 0m
- Greyhound US
  
  1h 30m
  
  0
  
  1:55 AM
  
  Lexington, KY
  Greyhound Bus Station
  
  3:25 AM
  
  Cincinnati
  E Galbraith Rd
  
  0
  
  Economy
  
  $14
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Lexington, KY (USA) at 6/11/2026 1:55:00 AM to E Galbraith Rd, Cincinnati (USA) arriving at 6/11/2026 3:25:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 1h 30m
Travel time is the same as the direct connection, but you will save $15

Best Price Offer: The price for the cheapest bus from Greenville, SC to Cincinnati is $78 on 6/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Greenville, SC and Cincinnati

See here how frequent the connections between Greenville, SC and Cincinnati are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Greenville, SC to Cincinnati. Thursday has instead the fewest connections, with only 2 daily coaches between Greenville, SC and Cincinnati.

The busiest time of the day is the Afternoon, with 12 buses from Greenville, SC to Cincinnati, while Evening sees the fewest connections between Greenville, SC and Cincinnati, with 5 offers.

Facts about the bus from Greenville, SC to Cincinnati

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Greenville, SC to Cincinnati in one click! Book your bus ticket from Greenville, SC to Cincinnati starting from $78!

Cheapest Bus	$78
Fastest Bus	12h 40m
Earliest Bus	2:45 PM
Latest Bus	7:40 PM
Daily Bus Routes	4 Ø
Distance	316.4 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Cincinnati

Every day, 4 buses from 2 bus companies leave Greenville, SC for Cincinnati: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/31

Monday 06/01

Tuesday 06/02

Wednesday 06/03

Thursday 06/04

$78

Friday 06/05

Saturday 06/06

$89

Sunday 06/07

$86

Monday 06/08

$86

Tuesday 06/09

Wednesday 06/10

Thursday 06/11

Friday 06/12

$93

Saturday 06/13

Sunday 06/14

$92

Monday 06/15

Tuesday 06/16

$80

Wednesday 06/17

Thursday 06/18

$85

Friday 06/19

$82

Saturday 06/20

$88

Sunday 06/21

Monday 06/22

Tuesday 06/23

$87

Wednesday 06/24

Thursday 06/25

$84

Friday 06/26

Saturday 06/27

The cheapest time to travel from Greenville, SC to Cincinnati

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Cincinnati, for the next 30 days.

With a price starting from $78, Thursday is the cheapest day for a bus from Greenville, SC to Cincinnati. Saturday instead is the most expensive day with prices starting from $88.

Afternoon is the cheapest day time for bus tickets from Greenville, SC to Cincinnati, with $78. Evening is the most expensive time of the day with prices starting from $86.

How to save money travelling from Greenville, SC to Cincinnati

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Cincinnati in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Cincinnati, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Cincinnati are also emptier.

All bus stations and stops in Greenville, SC and Cincinnati

In the map below, you can see where to find all bus stations in Greenville, SC and Cincinnati.

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

N Church St

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

University of Cincinnati

Commons Way 2815

Greyhound Bus Station

Gilbert Ave 1005

E Galbraith Rd

Downtown

E Court St 419

Bus Stop

Service and Comfort on the bus from Greenville, SC to Cincinnati

Want to know which seat classes are available on the buses from Greenville, SC to Cincinnati? Or which bus companies serve the route Greenville, SC to Cincinnati? Below you will find answers to your questions.

FAQs about the Greenville, SC to Cincinnati bus

How much does a Greenville, SC Cincinnati bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $78 and takes 12h 40m to reach Cincinnati. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Cincinnati?

This route is offered by 2 companies with a range of ticket prices between $78 and $96. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Cincinnati.

On average, how many connections are available from Greenville, SC to Cincinnati each day?

Every day, the Greenville, SC to Cincinnati bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Cincinnati take?

The fastest bus from Greenville, SC to Cincinnati is offered by Greyhound US and takes 12h 40m. Bus tickets for this connection cost $82. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Cincinnati?

The earliest bus arriving in Cincinnati from Greenville, SC starts at 2:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Cincinnati?

The latest bus trip departing from Greenville, SC for Cincinnati starts at 7:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Cincinnati route?

When traveling by bus from Greenville, SC to Cincinnati, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Cincinnati?

You can check all the direct connections between Greenville, SC and Cincinnati by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Cincinnati bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Cincinnati bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Cincinnati bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Cincinnati on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Cincinnati?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Greenville, SC and Cincinnati. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Cincinnati?

Prices and availability for 4 trips between Greenville, SC and Cincinnati change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Cincinnati

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Cincinnati

Here’s an overview of the most popular bus routes to Greenville, SC and to Cincinnati. Simply click on the connection of your choice, and you will find all the details about your bus route!