Bus Greenville, SC to San Antonio, TX

Compare all timetables for the bus from Greenville, SC to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to San Antonio, TX from various bus operators like FlixBus or Greyhound US for the next days.

today

$141

tomorrow

Thursday

Friday

Saturday

Sunday

Monday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 35m	2:45 PM	Greenville, SC	Woodruff Rd	3:20 PM	San Antonio, TX	Bus Station	Economy	$141	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/16/2025 2:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/17/2025 3:20:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 25h 35m
FlixBus	44h 35m	10:00 PM	Greenville, SC	Woodruff Rd	5:35 PM	San Antonio, TX	Bus Station	Economy	$144	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/16/2025 10:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/18/2025 5:35:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 44h 35m
FlixBus	37h 45m	4:15 PM	Greenville, SC	Woodruff Rd	5:00 AM	San Antonio, TX	Bus Station	Economy	$180	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/16/2025 4:15:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/18/2025 5:00:00 AM. 50 Economy ticket for $180 per person are available. Travel duration is 37h 45m

Best Price Offer: The price for the cheapest bus from Greenville, SC to San Antonio, TX is $129 on 12/15/2025. Flexible travelers save on ticket prices.

Facts about the bus from Greenville, SC to San Antonio, TX

Compare all providers like FlixBus and Greyhound US that travel 3 times every day by bus from Greenville, SC to San Antonio, TX in one click! Book your bus ticket from Greenville, SC to San Antonio, TX starting from $129!

Cheapest Bus	$129
Fastest Bus	24h 35m
Earliest Bus	2:45 PM
Latest Bus	10:00 PM
Daily Bus Routes	3 Ø
Distance	1,012.1 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to San Antonio, TX

Every day, 3 buses from 2 bus companies leave Greenville, SC for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

$141

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$167

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

How to save money travelling from Greenville, SC to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to San Antonio, TX are also emptier.

All bus stations and stops in Greenville, SC and San Antonio, TX

In the map below, you can see where to find all bus stations in Greenville, SC and San Antonio, TX.

McDonald's

Woodruff Rd 1111

Guadalajara Supermarket

White Horse Rd 2803

Greyhound Bus Station

Hendrix Dr 9

N Church St

Woodruff Rd

Woodruff Rd 1116

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

Service and Comfort on the bus from Greenville, SC to San Antonio, TX

Want to know which seat classes are available on the buses from Greenville, SC to San Antonio, TX? Or which bus companies serve the route Greenville, SC to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Greenville, SC to San Antonio, TX bus

How much does a Greenville, SC San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $129 and takes 24h 35m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $129 and $180. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Greenville, SC to San Antonio, TX each day?

Every day, the Greenville, SC to San Antonio, TX bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to San Antonio, TX take?

The fastest bus from Greenville, SC to San Antonio, TX is offered by Greyhound US and takes 24h 35m. Bus tickets for this connection cost $141. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Greenville, SC starts at 2:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to San Antonio, TX?

The latest bus trip departing from Greenville, SC for San Antonio, TX starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC San Antonio, TX route?

When traveling by bus from Greenville, SC to San Antonio, TX, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and San Antonio, TX?

You can check all the direct connections between Greenville, SC and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Greenville, SC and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to San Antonio, TX?

Prices and availability for 3 trips between Greenville, SC and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to San Antonio, TX

Here’s an overview of the most popular bus routes to Greenville, SC and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!