Which bus from Greenville, SC to San Luis Potosí is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $221
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Compare all timetables for the bus from Greenville, SC to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to San Luis Potosí from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
$221
Saturday
$221
Sunday
Monday
$221
Tuesday
Wednesday
$221

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 45h 45m 7:45 PM Greenville, SC Woodruff Rd 4:30 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $221
Greyhound US 49h 5m 2:45 PM Greenville, SC Woodruff Rd 2:50 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $221
FlixBus 41h 40m 1:20 PM Greenville, SC Woodruff Rd 6:00 AM San Luis Potosí Soriana El Paseo Bus Station  Economy $226
FlixBus 49h 50m 10:00 PM Greenville, SC Woodruff Rd 10:50 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $250
  • Did you know that if you travel from Greenville, SC to San Luis Potosí via Monterrey, NL, you can save more than $28? You can find the corresponding connections below.
    • FlixBus
      45h 48m
      0
      1:20 PM
      Greenville, SC
      Woodruff Rd
      8:25 PM
      Monterrey, NL
      Sendero Bus Station
      0
      FlixBus
      Economy
      $162
      • Waiting Time 9h 35m
    • ClickBus MX
      4h 8m
      0
      6:00 AM
      Monterrey, NL
      Central Bus Station
      10:08 AM
      San Luis Potosí
      Av Constitución / Manual José Othón Bus Stop
      0
      ClickBus MX
      Economy
      $32
    Travel time is 5h 8m longer, but you will save $28

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 49h 5m 2:45 PM Greenville, SC Woodruff Rd 2:50 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $221
FlixBus 41h 40m 1:20 PM Greenville, SC Woodruff Rd 6:00 AM San Luis Potosí Soriana El Paseo Bus Station  Economy $222
FlixBus 45h 45m 7:45 PM Greenville, SC Woodruff Rd 4:30 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $224
FlixBus 49h 50m 10:00 PM Greenville, SC Woodruff Rd 10:50 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $238
  • Did you know that if you travel from Greenville, SC to San Luis Potosí via Monterrey, NL, you can save more than $28? You can find the corresponding connections below.
    • FlixBus
      45h 48m
      0
      1:20 PM
      Greenville, SC
      Woodruff Rd
      8:25 PM
      Monterrey, NL
      Sendero Bus Station
      0
      FlixBus
      Economy
      $162
      • Waiting Time 9h 35m
    • ClickBus MX
      4h 8m
      0
      6:00 AM
      Monterrey, NL
      Central Bus Station
      10:08 AM
      San Luis Potosí
      Av Constitución / Manual José Othón Bus Stop
      0
      ClickBus MX
      Economy
      $32
    Travel time is 5h 8m longer, but you will save $28

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 45h 45m 7:45 PM Greenville, SC Woodruff Rd 4:30 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $221
Greyhound US 49h 5m 2:45 PM Greenville, SC Woodruff Rd 2:50 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $230
FlixBus 49h 50m 10:00 PM Greenville, SC Woodruff Rd 10:50 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $231
  • Did you know that if you travel from Greenville, SC to San Luis Potosí via Monterrey, NL, you can save more than $28? You can find the corresponding connections below.
    • FlixBus
      38h 25m
      0
      1:20 PM
      Greenville, SC
      Woodruff Rd
      8:25 PM
      Monterrey, NL
      Sendero Bus Station
      0
      FlixBus
      Economy
      $162
      • Waiting Time 1h 35m
    • ClickBus MX
      4h 45m
      0
      10:00 PM
      Monterrey, NL
      Central Bus Station
      2:45 AM
      San Luis Potosí
      Av Constitución / Manual José Othón Bus Stop
      0
      ClickBus MX
      Economy
      $32
    Travel Time is 6h 20m shorter, and you will save $28

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 49h 5m 2:45 PM Greenville, SC Woodruff Rd 2:50 PM San Luis Potosí Soriana El Paseo Bus Station  Economy $221
FlixBus 41h 40m 1:20 PM Greenville, SC Woodruff Rd 6:00 AM San Luis Potosí Soriana El Paseo Bus Station  Economy $222
  • Did you know that if you travel from Greenville, SC to San Luis Potosí via Monterrey, NL, you can save more than $32? You can find the corresponding connections below.
    • FlixBus
      59h 10m
      0
      1:20 PM
      Greenville, SC
      Woodruff Rd
      8:25 PM
      Monterrey, NL
      Sendero Bus Station
      0
      FlixBus
      Economy
      $162
      • Waiting Time 20h 35m
    • Busbud
      6h 30m
      0
      5:00 PM
      Monterrey, NL
      Central Bus Station
      11:30 PM
      San Luis Potosí
      Central Bus Station
      0
      Busbud
      Premium Economy
      $28
    Travel time is 18h 30m longer, but you will save $32

Best Price Offer: The price for the cheapest bus from Greenville, SC to San Luis Potosí is $221 on 12/5/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Greenville, SC and San Luis Potosí

See here how frequent the connections between Greenville, SC and San Luis Potosí are, during different times and days of the week.
Friday is the busiest day, with more than 4 daily buses from Greenville, SC to San Luis Potosí. Wednesday has instead the fewest connections, with only 2 daily coaches between Greenville, SC and San Luis Potosí.
The busiest time of the day is the Afternoon, with 7 buses from Greenville, SC to San Luis Potosí, while Evening sees the fewest connections between Greenville, SC and San Luis Potosí, with 6 offers.

Facts about the bus from Greenville, SC to San Luis Potosí

Compare all providers like FlixBus and Greyhound US that travel 3 times every day by bus from Greenville, SC to San Luis Potosí in one click! Book your bus ticket from Greenville, SC to San Luis Potosí starting from $221!

Cheapest Bus $221
Fastest Bus 40h 40m
Earliest Bus 1:20 PM
Latest Bus 2:45 PM
Daily Bus Routes 3 Ø
Distance 1,424.6 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to San Luis Potosí

Every day, 3 buses from 2 bus companies leave Greenville, SC for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
Friday 12/05
$221
Saturday 12/06
$221
Sunday 12/07
Monday 12/08
$221
Tuesday 12/09
Wednesday 12/10
$221
Thursday 12/11
$221
Friday 12/12
Saturday 12/13
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27

The cheapest time to travel from Greenville, SC to San Luis Potosí

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to San Luis Potosí, for the next 30 days.
With a price starting from $221, Monday is the cheapest day for a bus from Greenville, SC to San Luis Potosí. Monday instead is the most expensive day with prices starting from $221.
Afternoon is the cheapest day time for bus tickets from Greenville, SC to San Luis Potosí, with $221. Afternoon is the most expensive time of the day with prices starting from $221.

How to save money travelling from Greenville, SC to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to San Luis Potosí are also emptier.

Beloved bus companies from Greenville, SC to San Luis Potosí

These are the most booked bus companies between Greenville, SC to San Luis Potosí from our users.

Greyhound US from Greenville, SC to San Luis Potosí

Greyhound US

Here you will find the key facts about the Greyhound US bus route Greenville, SC to San Luis Potosí:

Cheapest Price $221
Fastest Bus 48h 5m
Earliest Bus 2:45 PM
Last Bus 2:45 PM
Daily Connections 1 Ø
Found on 12/1/2025

All bus stations and stops in Greenville, SC and San Luis Potosí

In the map below, you can see where to find all bus stations in Greenville, SC and San Luis Potosí.

Service and Comfort on the bus from Greenville, SC to San Luis Potosí

Want to know which seat classes are available on the buses from Greenville, SC to San Luis Potosí? Or which bus companies serve the route Greenville, SC to San Luis Potosí? Below you will find answers to your questions.

FAQs about the Greenville, SC to San Luis Potosí bus

How much does a Greenville, SC San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $221 and takes 48h 5m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to San Luis Potosí?

This route is offered by 2 companies with a range of ticket prices between $221 and $250. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from Greenville, SC to San Luis Potosí each day?

Every day, the Greenville, SC to San Luis Potosí bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to San Luis Potosí take?

The fastest bus from Greenville, SC to San Luis Potosí is offered by FlixBus and takes 40h 40m. Bus tickets for this connection cost $226. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from Greenville, SC starts at 1:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to San Luis Potosí?

The latest bus trip departing from Greenville, SC for San Luis Potosí starts at 2:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC San Luis Potosí route?

When traveling by bus from Greenville, SC to San Luis Potosí, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and San Luis Potosí?

You can check all the direct connections between Greenville, SC and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to San Luis Potosí on your planned travel date.

Available seat classes which are offered on the bus route Greenville, SC to San Luis Potosí

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to San Luis Potosí

Here’s an overview of the most popular bus routes to Greenville, SC and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus Puerto Vallarta to San Luis Potosí Bus Puerto Vallarta to San Luis Potosí
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Popular Airport Shuttles to Greenville, SC and to San Luis Potosí
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