Bus Greenville, SC to San Luis Potosí

Compare all timetables for the bus from Greenville, SC to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to San Luis Potosí from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$216

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Wednesday

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Friday

Saturday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	49h 0m	2:50 PM	Greenville, SC	Woodruff Rd	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$216	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 11/2/2026 2:50:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 11/4/2026 2:50:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 49h 0m
FlixBus	50h 15m	9:35 PM	Greenville, SC	Woodruff Rd	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 11/2/2026 9:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 11/4/2026 10:50:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 50h 15m
Greyhound US	45h 50m	8:20 PM	Greenville, SC	Woodruff Rd	5:10 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$226	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 11/2/2026 8:20:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 11/4/2026 5:10:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 45h 50m

Did you know that if you travel from Greenville, SC to San Luis Potosí via Monterrey, NL, you can save more than $39? You can find the corresponding connections below.
- FlixBus
  
  46h 10m
  
  0
  
  8:00 PM
  
  Greenville, SC
  Woodruff Rd
  
  7:45 AM
  
  Monterrey, NL
  Sendero Bus Station
  
  0
  
  Economy
  
  $151
  
  A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 11/2/2026 8:00:00 PM to Sendero Bus Station, Monterrey, NL (Mexico) arriving at 11/4/2026 7:45:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 36h 45m
- Flix Mexico
  
  8h 10m
  
  0
  
  9:00 AM
  
  Monterrey, NL
  Sendero Bus Station
  
  5:10 PM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Flix Mexico goes from Sendero Bus Station, Monterrey, NL (Mexico) at 11/4/2026 9:00:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 11/4/2026 5:10:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 8h 10m
Travel time is 1h 20m longer, but you will save $39

Best Price Offer: The price for the cheapest bus from Greenville, SC to San Luis Potosí is $216 on 11/2/2026. Flexible travelers save on ticket prices.

Facts about the bus from Greenville, SC to San Luis Potosí

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from Greenville, SC to San Luis Potosí in one click! Book your bus ticket from Greenville, SC to San Luis Potosí starting from $216!

Cheapest Bus	$216
Fastest Bus	44h 50m
Earliest Bus	2:50 PM
Latest Bus	9:35 PM
Daily Bus Routes	3 Ø
Distance	1,424.6 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Greenville, SC to San Luis Potosí

Every day, 3 buses from 2 bus companies leave Greenville, SC for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/01/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/01

Monday 11/02

$216

Tuesday 11/03

Wednesday 11/04

Thursday 11/05

Friday 11/06

Saturday 11/07

Sunday 11/08

Monday 11/09

Tuesday 11/10

Wednesday 11/11

Thursday 11/12

Friday 11/13

Saturday 11/14

Sunday 11/15

Monday 11/16

Tuesday 11/17

Wednesday 11/18

Thursday 11/19

Friday 11/20

Saturday 11/21

Sunday 11/22

Monday 11/23

Tuesday 11/24

Wednesday 11/25

Thursday 11/26

Friday 11/27

Saturday 11/28

How to save money travelling from Greenville, SC to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to San Luis Potosí are also emptier.

All bus stations and stops in Greenville, SC and San Luis Potosí

In the map below, you can see where to find all bus stations in Greenville, SC and San Luis Potosí.

N Church St

Woodruff Rd

Woodruff Rd 1116

McDonald's

Woodruff Rd 1111

Guadalajara Supermarket

White Horse Rd 2803

Greyhound Bus Station

Hendrix Dr 9

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Trojes del Horizonte

Service and Comfort on the bus from Greenville, SC to San Luis Potosí

Want to know which seat classes are available on the buses from Greenville, SC to San Luis Potosí? Or which bus companies serve the route Greenville, SC to San Luis Potosí? Below you will find answers to your questions.

FAQs about the Greenville, SC to San Luis Potosí bus

How much does a Greenville, SC San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $216 and takes 48h 0m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to San Luis Potosí?

This route is offered by 2 companies with a range of ticket prices between $216 and $226. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from Greenville, SC to San Luis Potosí each day?

Every day, the Greenville, SC to San Luis Potosí bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to San Luis Potosí take?

The fastest bus from Greenville, SC to San Luis Potosí is offered by Greyhound US and takes 44h 50m. Bus tickets for this connection cost $226. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from Greenville, SC starts at 2:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to San Luis Potosí?

The latest bus trip departing from Greenville, SC for San Luis Potosí starts at 9:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC San Luis Potosí route?

When traveling by bus from Greenville, SC to San Luis Potosí, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and San Luis Potosí?

You can check all the direct connections between Greenville, SC and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Greenville, SC to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to San Luis Potosí on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to San Luis Potosí?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Greenville, SC and San Luis Potosí. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to San Luis Potosí?

Prices and availability for 3 trips between Greenville, SC and San Luis Potosí change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to San Luis Potosí

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to San Luis Potosí

Here’s an overview of the most popular bus routes to Greenville, SC and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!