Which bus from Greenville, SC to Santiago de Queretaro is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $217
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Compare all timetables for the bus from Greenville, SC to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Santiago de Queretaro from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
Monday
Tuesday
Wednesday
$219
Thursday
Friday
$218

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 46h 45m 1:20 PM Greenville, SC Woodruff Rd 10:05 AM Santiago de Queretaro Prol Zaragoza Y City Club Las Plazas Bus Stop  Economy $219
Greyhound US 48h 20m 8:20 PM Greenville, SC Woodruff Rd 6:40 PM Santiago de Queretaro Prol Zaragoza Y City Club Las Plazas Bus Stop  Economy $227
FlixBus 62h 30m 9:35 PM Greenville, SC Woodruff Rd 10:05 AM Santiago de Queretaro Prol Zaragoza Y City Club Las Plazas Bus Stop  Economy $228
  • Did you know that if you travel from Greenville, SC to Santiago de Queretaro via Atlanta, GA, you can save more than $65? You can find the corresponding connections below.
    • FlixBus
      64h 5m
      0
      8:00 PM
      Greenville, SC
      Woodruff Rd
      10:40 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $18
      • Waiting Time 18h 0m
    • Greyhound US
      43h 25m
      0
      4:40 PM
      Atlanta, GA
      Garnett Transit Station
      10:05 AM
      Santiago de Queretaro
      Centro Comercial Galeria
      0
      Greyhound US
      Economy
      $136
    Travel time is 19h 20m longer, but you will save $65

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 48h 20m 8:20 PM Greenville, SC Woodruff Rd 6:40 PM Santiago de Queretaro Prol Zaragoza Y City Club Las Plazas Bus Stop  Economy $218
FlixBus 46h 45m 1:20 PM Greenville, SC Woodruff Rd 10:05 AM Santiago de Queretaro Prol Zaragoza Y City Club Las Plazas Bus Stop  Economy $219
FlixBus 54h 35m 9:35 PM Greenville, SC Woodruff Rd 2:10 AM Santiago de Queretaro Prol Zaragoza Y City Club Las Plazas Bus Stop  Economy $231
  • Did you know that if you travel from Greenville, SC to Santiago de Queretaro via Atlanta, GA, you can save more than $69? You can find the corresponding connections below.
    • Greyhound US
      55h 50m
      0
      8:20 PM
      Greenville, SC
      Woodruff Rd
      11:30 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 7h 25m
    • Greyhound US
      45h 15m
      0
      6:55 AM
      Atlanta, GA
      Garnett Transit Station
      2:10 AM
      Santiago de Queretaro
      Centro Comercial Galeria
      0
      Greyhound US
      Economy
      $128
    Travel time is 11h 5m longer, but you will save $69

Best Price Offer: The price for the cheapest bus from Greenville, SC to Santiago de Queretaro is $217 on 10/9/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Greenville, SC and Santiago de Queretaro

See here how frequent the connections between Greenville, SC and Santiago de Queretaro are, during different times and days of the week.
Friday is the busiest day, with more than 6 daily buses from Greenville, SC to Santiago de Queretaro. Wednesday has instead the fewest connections, with only 3 daily coaches between Greenville, SC and Santiago de Queretaro.
The busiest time of the day is the Evening, with 6 buses from Greenville, SC to Santiago de Queretaro, while Afternoon sees the fewest connections between Greenville, SC and Santiago de Queretaro, with 3 offers.

Facts about the bus from Greenville, SC to Santiago de Queretaro

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Greenville, SC to Santiago de Queretaro in one click! Book your bus ticket from Greenville, SC to Santiago de Queretaro starting from $217!

Cheapest Bus $217
Fastest Bus 44h 45m
Earliest Bus 1:20 PM
Latest Bus 9:35 PM
Daily Bus Routes 4 Ø
Distance 1,472.3 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Santiago de Queretaro

Every day, 4 buses from 2 bus companies leave Greenville, SC for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/19/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 09/13
Monday 09/14
Tuesday 09/15
Wednesday 09/16
Thursday 09/17
Friday 09/18
Saturday 09/19
Sunday 09/20
Monday 09/21
Tuesday 09/22
Wednesday 09/23
$219
Thursday 09/24
Friday 09/25
$222
Saturday 09/26
$219
Sunday 09/27
Monday 09/28
Tuesday 09/29
Wednesday 09/30
$219
Thursday 10/01
Friday 10/02
Saturday 10/03
Sunday 10/04
Monday 10/05
Tuesday 10/06
$227
Wednesday 10/07
$219
Thursday 10/08
$223
Friday 10/09
$217
Saturday 10/10

The cheapest time to travel from Greenville, SC to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Santiago de Queretaro, for the next 30 days.
With a price starting from $217, Friday is the cheapest day for a bus from Greenville, SC to Santiago de Queretaro. Wednesday instead is the most expensive day with prices starting from $219.
Evening is the cheapest day time for bus tickets from Greenville, SC to Santiago de Queretaro, with $218. Afternoon is the most expensive time of the day with prices starting from $219.

How to save money travelling from Greenville, SC to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Santiago de Queretaro are also emptier.

Beloved bus companies from Greenville, SC to Santiago de Queretaro

These are the most booked bus companies between Greenville, SC to Santiago de Queretaro from our users.

FlixBus from Greenville, SC to Santiago de Queretaro

FlixBus

Here you will find the key facts about the FlixBus bus route Greenville, SC to Santiago de Queretaro:

Cheapest Price $219
Fastest Bus 44h 45m
Earliest Bus 1:20 PM
Last Bus 9:35 PM
Daily Connections 3 Ø
Found on 8/26/2026

All bus stations and stops in Greenville, SC and Santiago de Queretaro

In the map below, you can see where to find all bus stations in Greenville, SC and Santiago de Queretaro.

Service and Comfort on the bus from Greenville, SC to Santiago de Queretaro

Want to know which seat classes are available on the buses from Greenville, SC to Santiago de Queretaro? Or which bus companies serve the route Greenville, SC to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the Greenville, SC to Santiago de Queretaro bus

How much does a Greenville, SC Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $217 and takes 46h 20m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Santiago de Queretaro?

This route is offered by 2 companies with a range of ticket prices between $217 and $235. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from Greenville, SC to Santiago de Queretaro each day?

Every day, the Greenville, SC to Santiago de Queretaro bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Santiago de Queretaro take?

The fastest bus from Greenville, SC to Santiago de Queretaro is offered by FlixBus and takes 44h 45m. Bus tickets for this connection cost $219. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from Greenville, SC starts at 1:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Santiago de Queretaro?

The latest bus trip departing from Greenville, SC for Santiago de Queretaro starts at 9:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Santiago de Queretaro route?

When traveling by bus from Greenville, SC to Santiago de Queretaro, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Santiago de Queretaro?

You can check all the direct connections between Greenville, SC and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Santiago de Queretaro on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Santiago de Queretaro?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Greenville, SC and Santiago de Queretaro. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Santiago de Queretaro?

Prices and availability for 4 trips between Greenville, SC and Santiago de Queretaro change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Santiago de Queretaro

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to Greenville, SC and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Greenville, SC and to Santiago de Queretaro
CheckMyBus › Buses in USA › Bus to Greenville, SC › Bus to Santiago de Queretaro

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