Bus Greenville, SC to Tampa - Compare all Companies

Compare all timetables for the bus from Greenville, SC to Tampa

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Tampa from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$127

Monday

Tuesday

Wednesday

$122

Thursday

Friday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 45m	7:45 PM	Greenville, SC	Woodruff Rd	11:30 AM	Tampa	Marion Street	Economy	$127	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/21/2025 7:45:00 PM to Marion Street, Tampa (USA) arriving at 12/22/2025 11:30:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 15h 45m
FlixBus	24h 25m	10:00 PM	Greenville, SC	Woodruff Rd	10:25 PM	Tampa	Marion Street	Economy	$127	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/21/2025 10:00:00 PM to Marion Street, Tampa (USA) arriving at 12/22/2025 10:25:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 24h 25m
FlixBus	16h 45m	7:45 PM	Greenville, SC	Woodruff Rd	12:30 PM	Tampa	USF	Economy	$127	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/21/2025 7:45:00 PM to USF, Tampa (USA) arriving at 12/22/2025 12:30:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 16h 45m
Greyhound US	18h 45m	2:45 PM	Greenville, SC	Woodruff Rd	9:30 AM	Tampa	USF	Economy	$127	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/21/2025 2:45:00 PM to USF, Tampa (USA) arriving at 12/22/2025 9:30:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 18h 45m
Greyhound US	19h 15m	2:45 PM	Greenville, SC	Woodruff Rd	10:00 AM	Tampa	Marion Street	Economy	$129	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/21/2025 2:45:00 PM to Marion Street, Tampa (USA) arriving at 12/22/2025 10:00:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 19h 15m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 40m	1:20 PM	Greenville, SC	Woodruff Rd	6:00 AM	Tampa	Marion Street	Economy	$122	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/24/2025 1:20:00 PM to Marion Street, Tampa (USA) arriving at 12/25/2025 6:00:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 16h 40m
Greyhound US	19h 15m	2:45 PM	Greenville, SC	Woodruff Rd	10:00 AM	Tampa	Marion Street	Economy	$122	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/24/2025 2:45:00 PM to Marion Street, Tampa (USA) arriving at 12/25/2025 10:00:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 19h 15m
Greyhound US	18h 45m	2:45 PM	Greenville, SC	Woodruff Rd	9:30 AM	Tampa	USF	Economy	$122	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/24/2025 2:45:00 PM to USF, Tampa (USA) arriving at 12/25/2025 9:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 18h 45m
FlixBus	24h 25m	10:00 PM	Greenville, SC	Woodruff Rd	10:25 PM	Tampa	Marion Street	Economy	$124	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/24/2025 10:00:00 PM to Marion Street, Tampa (USA) arriving at 12/25/2025 10:25:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 24h 25m
FlixBus	17h 15m	7:45 PM	Greenville, SC	Woodruff Rd	1:00 PM	Tampa	Marion Street	Economy	$140	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/24/2025 7:45:00 PM to Marion Street, Tampa (USA) arriving at 12/25/2025 1:00:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 17h 15m

Best Price Offer: The price for the cheapest bus from Greenville, SC to Tampa is $105 on 12/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Greenville, SC and Tampa

See here how frequent the connections between Greenville, SC and Tampa are, during different times and days of the week.

Sunday is the busiest day, with more than 12 daily buses from Greenville, SC to Tampa. Wednesday has instead the fewest connections, with only 6 daily coaches between Greenville, SC and Tampa.

The busiest time of the day is the Afternoon, with 9 buses from Greenville, SC to Tampa, while Afternoon sees the fewest connections between Greenville, SC and Tampa, with 9 offers.

Facts about the bus from Greenville, SC to Tampa

Compare all providers like FlixBus and Greyhound US that travel 9 times every day by bus from Greenville, SC to Tampa in one click! Book your bus ticket from Greenville, SC to Tampa starting from $105!

Cheapest Bus	$105
Fastest Bus	15h 45m
Earliest Bus	1:20 PM
Latest Bus	10:00 PM
Daily Bus Routes	9 Ø
Distance	476.7 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Tampa

Every day, 9 buses from 2 bus companies leave Greenville, SC for Tampa: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/20/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

$128

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$122

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

$124

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

$127

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Greenville, SC to Tampa

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Tampa, for the next 30 days.

With a price starting from $92, Sunday is the cheapest day for a bus from Greenville, SC to Tampa. Wednesday instead is the most expensive day with prices starting from $122.

Afternoon is the cheapest day time for bus tickets from Greenville, SC to Tampa, with $122. Evening is the most expensive time of the day with prices starting from $124.

How to save money travelling from Greenville, SC to Tampa

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Tampa in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Tampa, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Tampa are also emptier.

All bus stations and stops in Greenville, SC and Tampa

In the map below, you can see where to find all bus stations in Greenville, SC and Tampa.

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

Guadalajara Supermarket

White Horse Rd 2803

Greyhound Bus Station

Hendrix Dr 9

N Church St

Marion Street

N Marion St 1211

USF

USF Holly Drive 3755

Greyhound Bus Station

East Polk Street 602

Western Union

Tampa Gateway Blvd, I 4 Exit 10 11706

Port of Tampa Cruise Terminals

Channelside Dr. 1101

Service and Comfort on the bus from Greenville, SC to Tampa

Want to know which seat classes are available on the buses from Greenville, SC to Tampa? Or which bus companies serve the route Greenville, SC to Tampa? Below you will find answers to your questions.

FAQs about the Greenville, SC to Tampa bus

How much does a Greenville, SC Tampa bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $105 and takes 16h 40m to reach Tampa. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Tampa?

This route is offered by 2 companies with a range of ticket prices between $105 and $141. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Tampa.

On average, how many connections are available from Greenville, SC to Tampa each day?

Every day, the Greenville, SC to Tampa bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Tampa take?

The fastest bus from Greenville, SC to Tampa is offered by FlixBus and takes 15h 45m. Bus tickets for this connection cost $127. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Tampa?

The earliest bus arriving in Tampa from Greenville, SC starts at 1:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Tampa?

The latest bus trip departing from Greenville, SC for Tampa starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Tampa route?

When traveling by bus from Greenville, SC to Tampa, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Tampa?

You can check all the direct connections between Greenville, SC and Tampa by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Tampa bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Tampa bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Tampa bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Tampa on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Tampa?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Greenville, SC and Tampa. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Tampa?

Prices and availability for 9 trips between Greenville, SC and Tampa change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Tampa

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Tampa

Here’s an overview of the most popular bus routes to Greenville, SC and to Tampa. Simply click on the connection of your choice, and you will find all the details about your bus route!