Bus Louisville, KY to Gainesville, FL: Compare prices and save money

Compare all timetables for the bus from Louisville, KY to Gainesville, FL

Here is a selection of the cheapest bus trips from the schedule from Louisville, KY to Gainesville, FL from various bus operators like Greyhound US or FlixBus for the next days.

today

$104

tomorrow

Tuesday

Wednesday

Thursday

Friday

$93

Saturday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	20h 15m	7:25 AM	Louisville, KY	Greyhound Bus Station	3:40 AM	Gainesville, FL	Rosa Parks Transfer station	Economy	$104	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 3/22/2026 7:25:00 AM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/23/2026 3:40:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 20h 15m
Greyhound US	15h 35m	2:05 PM	Louisville, KY	Greyhound Bus Station	5:40 AM	Gainesville, FL	Rosa Parks Transfer station	Economy	$104	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 3/22/2026 2:05:00 PM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/23/2026 5:40:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 15h 35m
Greyhound US	20h 10m	6:15 PM	Louisville, KY	Greyhound Bus Station	2:25 PM	Gainesville, FL	Rosa Parks Transfer station	Economy	$104	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 3/22/2026 6:15:00 PM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/23/2026 2:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 20h 10m
FlixBus	15h 10m	10:05 PM	Louisville, KY	Greyhound Bus Station	1:15 PM	Gainesville, FL	Greyhound Bus Station	Economy	$104	A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 3/22/2026 10:05:00 PM to Greyhound Bus Station, Gainesville, FL (USA) arriving at 3/23/2026 1:15:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 15h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 10m	10:05 PM	Louisville, KY	Greyhound Bus Station	1:15 PM	Gainesville, FL	North Walmart Supercenter Bus Stop	Economy	$93	A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 3/27/2026 10:05:00 PM to North Walmart Supercenter Bus Stop, Gainesville, FL (USA) arriving at 3/28/2026 1:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 15h 10m
Greyhound US	20h 15m	7:25 AM	Louisville, KY	Greyhound Bus Station	3:40 AM	Gainesville, FL	Rosa Parks Transfer station	Economy	$93	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 3/27/2026 7:25:00 AM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/28/2026 3:40:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 20h 15m
FlixBus	16h 25m	1:35 AM	Louisville, KY	Greyhound Bus Station	6:00 PM	Gainesville, FL	Rosa Parks Transfer station	Economy	$94	A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 3/27/2026 1:35:00 AM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/27/2026 6:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 25m
Greyhound US	17h 40m	3:35 AM	Louisville, KY	Greyhound Bus Station	9:15 PM	Gainesville, FL	Rosa Parks Transfer station	Economy	$94	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 3/27/2026 3:35:00 AM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/27/2026 9:15:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 17h 40m
Greyhound US	19h 5m	10:55 PM	Louisville, KY	Greyhound Bus Station	6:00 PM	Gainesville, FL	Rosa Parks Transfer station	Economy	$94	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 3/27/2026 10:55:00 PM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/28/2026 6:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 19h 5m

Did you know that if you travel from Louisville, KY to Gainesville, FL via Atlanta, GA, you can save more than $14? You can find the corresponding connections below.
- Greyhound US
  
  15h 45m
  
  0
  
  1:55 PM
  
  Louisville, KY
  Greyhound Bus Station
  
  11:15 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $43
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 3/28/2026 1:55:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 3/28/2026 11:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 9h 20m
- FlixBus
  
  5h 35m
  
  0
  
  12:05 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  5:40 AM
  
  Gainesville, FL
  Rosa Parks Transfer station
  
  0
  
  Economy
  
  $36
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 3/29/2026 12:05:00 AM to Rosa Parks Transfer station, Gainesville, FL (USA) arriving at 3/29/2026 5:40:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 5h 35m
Travel time is 0h 35m longer, but you will save $14

Best Price Offer: The price for the cheapest bus from Louisville, KY to Gainesville, FL is $82 on 4/17/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Louisville, KY and Gainesville, FL

See here how frequent the connections between Louisville, KY and Gainesville, FL are, during different times and days of the week.

Friday is the busiest day, with more than 18 daily buses from Louisville, KY to Gainesville, FL. Sunday has instead the fewest connections, with only 6 daily coaches between Louisville, KY and Gainesville, FL.

The busiest time of the day is the Evening, with 12 buses from Louisville, KY to Gainesville, FL, while Morning sees the fewest connections between Louisville, KY and Gainesville, FL, with 3 offers.

Facts about the bus from Louisville, KY to Gainesville, FL

Compare all providers like Greyhound US and FlixBus that travel 12 times every day by bus from Louisville, KY to Gainesville, FL in one click! Book your bus ticket from Louisville, KY to Gainesville, FL starting from $82!

Cheapest Bus	$82
Fastest Bus	15h 10m
Earliest Bus	7:25 AM
Latest Bus	10:55 PM
Daily Bus Routes	12 Ø
Distance	626.7 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Louisville, KY to Gainesville, FL

Every day, 12 buses from 2 bus companies leave Louisville, KY for Gainesville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

$104

Monday 03/23

Tuesday 03/24

Wednesday 03/25

Thursday 03/26

Friday 03/27

$97

Saturday 03/28

Sunday 03/29

$103

Monday 03/30

Tuesday 03/31

Wednesday 04/01

Thursday 04/02

Friday 04/03

Saturday 04/04

Sunday 04/05

$96

Monday 04/06

$93

Tuesday 04/07

$100

Wednesday 04/08

$94

Thursday 04/09

Friday 04/10

Saturday 04/11

$92

Sunday 04/12

Monday 04/13

$88

Tuesday 04/14

$95

Wednesday 04/15

Thursday 04/16

Friday 04/17

$82

Saturday 04/18

The cheapest time to travel from Louisville, KY to Gainesville, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Louisville, KY to Gainesville, FL, for the next 30 days.

With a price starting from $82, Friday is the cheapest day for a bus from Louisville, KY to Gainesville, FL. Sunday instead is the most expensive day with prices starting from $96.

Night is the cheapest day time for bus tickets from Louisville, KY to Gainesville, FL, with $82. Afternoon is the most expensive time of the day with prices starting from $104.

How to save money travelling from Louisville, KY to Gainesville, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Louisville, KY to Gainesville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to Gainesville, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to Gainesville, FL are also emptier.

All bus stations and stops in Louisville, KY and Gainesville, FL

In the map below, you can see where to find all bus stations in Louisville, KY and Gainesville, FL.

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Rosa Parks Transfer station

SE 3rd St 700

Greyhound Bus Station

Northeast 23rd Avenue 101

Central Bus Station

Westgate Plaza Bus Stop

University of Florida (Commuter Lot)

Gale Lemerand Dr

Service and Comfort on the bus from Louisville, KY to Gainesville, FL

Want to know which seat classes are available on the buses from Louisville, KY to Gainesville, FL? Or which bus companies serve the route Louisville, KY to Gainesville, FL? Below you will find answers to your questions.

FAQs about the Louisville, KY to Gainesville, FL bus

How much does a Louisville, KY Gainesville, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $82 and takes 20h 15m to reach Gainesville, FL. Compare offers to save money!

How much could I save by comparing buses from Louisville, KY to Gainesville, FL?

This route is offered by 2 companies with a range of ticket prices between $82 and $119. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Gainesville, FL.

On average, how many connections are available from Louisville, KY to Gainesville, FL each day?

Every day, the Louisville, KY to Gainesville, FL bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Louisville, KY to Gainesville, FL take?

The fastest bus from Louisville, KY to Gainesville, FL is offered by FlixBus and takes 15h 10m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Louisville, KY to Gainesville, FL?

The earliest bus arriving in Gainesville, FL from Louisville, KY starts at 7:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Louisville, KY to Gainesville, FL?

The latest bus trip departing from Louisville, KY for Gainesville, FL starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Louisville, KY Gainesville, FL route?

When traveling by bus from Louisville, KY to Gainesville, FL, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Louisville, KY and Gainesville, FL?

You can check all the direct connections between Louisville, KY and Gainesville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Louisville, KY to Gainesville, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Louisville, KY Gainesville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Louisville, KY Gainesville, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Louisville, KY to Gainesville, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Louisville, KY to Gainesville, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between Louisville, KY and Gainesville, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Louisville, KY to Gainesville, FL?

Prices and availability for 12 trips between Louisville, KY and Gainesville, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Louisville, KY to Gainesville, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Louisville, KY and to Gainesville, FL

Here’s an overview of the most popular bus routes to Louisville, KY and to Gainesville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!