Bus Mesa, AZ to Columbia, MO: Compare prices and save money

Compare all timetables for the bus from Mesa, AZ to Columbia, MO

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to Columbia, MO from various bus operators like Greyhound US for the next days.

today

tomorrow

$223

Wednesday

Thursday

Friday

Saturday

$223

Sunday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	36h 20m	9:10 PM	Mesa, AZ	Greyhound	10:30 AM	Columbia, MO	Red Thread		Economy	$223	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 1/20/2026 9:10:00 PM to Red Thread, Columbia, MO (USA) arriving at 1/22/2026 10:30:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 36h 20m
	Greyhound US	36h 30m	9:10 PM	Mesa, AZ	Greyhound	10:40 AM	Columbia, MO	Bus Stop		Economy	$225	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 1/20/2026 9:10:00 PM to Bus Stop, Columbia, MO (USA) arriving at 1/22/2026 10:40:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 36h 30m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	36h 20m	9:10 PM	Mesa, AZ	Greyhound	10:30 AM	Columbia, MO	Red Thread		Economy	$223	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 1/24/2026 9:10:00 PM to Red Thread, Columbia, MO (USA) arriving at 1/26/2026 10:30:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 36h 20m
	Greyhound US	36h 30m	9:10 PM	Mesa, AZ	Greyhound	10:40 AM	Columbia, MO	Bus Stop		Economy	$225	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 1/24/2026 9:10:00 PM to Bus Stop, Columbia, MO (USA) arriving at 1/26/2026 10:40:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 36h 30m

Did you know that if you travel from Mesa, AZ to Columbia, MO via St. Louis, MO, you can save more than $48? You can find the corresponding connections below.
- Busbud
  
  52h 50m
  
  0
  
  8:40 AM
  
  Mesa, AZ
  Greyhound
  
  10:45 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $149
  
  A Bus from Busbud goes from Greyhound, Mesa, AZ (USA) at 1/22/2026 8:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/23/2026 10:45:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 37h 5m
- FlixBus
  
  2h 35m
  
  0
  
  11:55 AM
  
  St. Louis, MO
  Gateway Station
  
  2:30 PM
  
  Columbia, MO
  Bus Stop
  
  0
  
  Economy
  
  $25
  
  A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 1/24/2026 11:55:00 AM to Bus Stop, Columbia, MO (USA) arriving at 1/24/2026 2:30:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 35m
Travel time is 15h 30m longer, but you will save $48

Best Price Offer: The price for the cheapest bus from Mesa, AZ to Columbia, MO is $223 on 1/20/2026. Flexible travelers save on ticket prices.

Facts about the bus from Mesa, AZ to Columbia, MO

Compare all providers like Greyhound US that travel 2 times every day by bus from Mesa, AZ to Columbia, MO in one click! Book your bus ticket from Mesa, AZ to Columbia, MO starting from $223!

Cheapest Bus	$223
Fastest Bus	37h 20m
Earliest Bus	9:10 PM
Latest Bus	9:10 PM
Daily Bus Routes	2 Ø
Distance	1,150.7 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mesa, AZ to Columbia, MO

Every day, 2 buses from 1 bus companies leave Mesa, AZ for Columbia, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

Tuesday 01/20

$223

Wednesday 01/21

Thursday 01/22

Friday 01/23

Saturday 01/24

$223

Sunday 01/25

Monday 01/26

Tuesday 01/27

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

How to save money travelling from Mesa, AZ to Columbia, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to Columbia, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to Columbia, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to Columbia, MO are also emptier.

All bus stations and stops in Mesa, AZ and Columbia, MO

In the map below, you can see where to find all bus stations in Mesa, AZ and Columbia, MO.

Greyhound

S Country Club Dr 1423

Fry’s Fuel Center

W Main Street 1235

Bus Stop

N 10th St 198

Red Thread

Highway 40 W 6401

University

Fellows Pl 1301-1349

Service and Comfort on the bus from Mesa, AZ to Columbia, MO

Want to know which seat classes are available on the buses from Mesa, AZ to Columbia, MO? Or which bus companies serve the route Mesa, AZ to Columbia, MO? Below you will find answers to your questions.

FAQs about the Mesa, AZ to Columbia, MO bus

How much does a Mesa, AZ Columbia, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $223 and takes 37h 20m to reach Columbia, MO. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to Columbia, MO?

This route is offered by 1 companies with a range of ticket prices between $223 and $225. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Columbia, MO.

On average, how many connections are available from Mesa, AZ to Columbia, MO each day?

Every day, the Mesa, AZ to Columbia, MO bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to Columbia, MO take?

The fastest bus from Mesa, AZ to Columbia, MO is offered by Greyhound US and takes 37h 20m. Bus tickets for this connection cost $223. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to Columbia, MO?

The earliest bus arriving in Columbia, MO from Mesa, AZ starts at 9:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to Columbia, MO?

The latest bus trip departing from Mesa, AZ for Columbia, MO starts at 9:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ Columbia, MO route?

When traveling by bus from Mesa, AZ to Columbia, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and Columbia, MO?

You can check all the direct connections between Mesa, AZ and Columbia, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to Columbia, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ Columbia, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ Columbia, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to Columbia, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Mesa, AZ to Columbia, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Mesa, AZ and Columbia, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mesa, AZ to Columbia, MO?

Prices and availability for 2 trips between Mesa, AZ and Columbia, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mesa, AZ to Columbia, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to Columbia, MO

Here’s an overview of the most popular bus routes to Mesa, AZ and to Columbia, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!