Bus Milan to Frankfurt am Main: Compare prices and save money

Compare all timetables for the bus from Milan to Frankfurt am Main

Here is a selection of the cheapest bus trips from the schedule from Milan to Frankfurt am Main from various bus operators like FlixBus for the next days.

today

$52

tomorrow

$46

Sunday

$50

Monday

$41

Tuesday

$42

Wednesday

$41

Thursday

$46

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 15m	1:15 AM	Milan	Lampugnano Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$52	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 1:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/6/2026 1:30:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 12h 15m
FlixBus	9h 35m	8:25 PM	Milan	Lampugnano Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$52	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 8:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/7/2026 6:00:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 9h 35m
FlixBus	11h 15m	11:30 AM	Milan	Lampugnano Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$62	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 11:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/6/2026 10:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 15m
FlixBus	10h 50m	7:00 PM	Milan	Lampugnano Bus Station	5:50 AM	Frankfurt am Main	Central Station	Economy	$65	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/6/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/7/2026 5:50:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 50m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 15m	1:15 AM	Milan	Lampugnano Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$46	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/7/2026 1:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/7/2026 1:30:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 12h 15m
FlixBus	15h 0m	7:30 AM	Milan	San Donato Bus Station	10:30 PM	Frankfurt am Main	Central Station	Economy	$47	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/7/2026 7:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/7/2026 10:30:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 0m
FlixBus	15h 5m	3:10 PM	Milan	San Donato Bus Station	6:15 AM	Frankfurt am Main	Central Station	Economy	$47	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/7/2026 3:10:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/8/2026 6:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 5m
FlixBus	9h 35m	8:25 PM	Milan	Lampugnano Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$50	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/7/2026 8:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/8/2026 6:00:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 9h 35m
FlixBus	11h 15m	11:30 AM	Milan	Lampugnano Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$52	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/7/2026 11:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/7/2026 10:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 11h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 15m	1:15 AM	Milan	Lampugnano Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$50	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/8/2026 1:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/8/2026 1:30:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 12h 15m
FlixBus	9h 35m	8:25 PM	Milan	Lampugnano Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$52	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/8/2026 8:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/9/2026 6:00:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 9h 35m
FlixBus	10h 50m	7:00 PM	Milan	Lampugnano Bus Station	5:50 AM	Frankfurt am Main	Central Station	Economy	$71	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/8/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/9/2026 5:50:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 10h 50m
FlixBus	11h 15m	11:30 AM	Milan	Lampugnano Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$87	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/8/2026 11:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/8/2026 10:45:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 11h 15m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	9h 35m	8:25 PM	Milan	Lampugnano Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$41	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 8:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/10/2026 6:00:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 9h 35m
FlixBus	12h 15m	1:15 AM	Milan	Lampugnano Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$44	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 1:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/9/2026 1:30:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 12h 15m
FlixBus	10h 35m	7:20 AM	Milan	Lampugnano Bus Station	5:55 PM	Frankfurt am Main	Central Station	Economy	$46	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 7:20:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/9/2026 5:55:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 35m
FlixBus	11h 15m	11:30 AM	Milan	Lampugnano Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$46	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 11:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/9/2026 10:45:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 15m
FlixBus	10h 50m	7:00 PM	Milan	Lampugnano Bus Station	5:50 AM	Frankfurt am Main	Central Station	Economy	$48	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/9/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/10/2026 5:50:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 10h 50m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 15m	1:15 AM	Milan	Lampugnano Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$42	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/10/2026 1:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/10/2026 1:30:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 12h 15m
FlixBus	11h 15m	11:30 AM	Milan	Lampugnano Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$44	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/10/2026 11:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/10/2026 10:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 15m
FlixBus	10h 50m	7:00 PM	Milan	Lampugnano Bus Station	5:50 AM	Frankfurt am Main	Central Station	Economy	$45	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/10/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/11/2026 5:50:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 50m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	9h 35m	8:25 PM	Milan	Lampugnano Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$41	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/11/2026 8:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/12/2026 6:00:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 9h 35m
FlixBus	12h 15m	1:15 AM	Milan	Lampugnano Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$42	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/11/2026 1:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/11/2026 1:30:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 12h 15m
FlixBus	11h 15m	11:30 AM	Milan	Lampugnano Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$44	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/11/2026 11:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/11/2026 10:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 15m
FlixBus	10h 50m	7:00 PM	Milan	Lampugnano Bus Station	5:50 AM	Frankfurt am Main	Central Station	Economy	$48	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/11/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/12/2026 5:50:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 10h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 35m	7:20 AM	Milan	Lampugnano Bus Station	5:55 PM	Frankfurt am Main	Central Station	Economy	$46	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/12/2026 7:20:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/12/2026 5:55:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 35m
FlixBus	9h 35m	8:25 PM	Milan	Lampugnano Bus Station	6:00 AM	Frankfurt am Main	Central Station	Economy	$46	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/12/2026 8:25:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/13/2026 6:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 35m
FlixBus	12h 15m	1:15 AM	Milan	Lampugnano Bus Station	1:30 PM	Frankfurt am Main	Central Station	Economy	$48	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/12/2026 1:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/12/2026 1:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 12h 15m
FlixBus	11h 15m	11:30 AM	Milan	Lampugnano Bus Station	10:45 PM	Frankfurt am Main	Central Station	Economy	$51	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/12/2026 11:30:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 2/12/2026 10:45:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 15m
FlixBus	10h 50m	7:00 PM	Milan	Lampugnano Bus Station	5:50 AM	Frankfurt am Main	Central Station	Economy	$62	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/12/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 2/13/2026 5:50:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 10h 50m

Best Price Offer: The price for the cheapest bus from Milan to Frankfurt am Main is $38 on 2/26/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milan and Frankfurt am Main

See here how frequent the connections between Milan and Frankfurt am Main are, during different times and days of the week.

Saturday is the busiest day, with more than 7 daily buses from Milan to Frankfurt am Main. Tuesday has instead the fewest connections, with only 3 daily coaches between Milan and Frankfurt am Main.

The busiest time of the day is the Evening, with 13 buses from Milan to Frankfurt am Main, while Afternoon sees the fewest connections between Milan and Frankfurt am Main, with 1 offers.

Facts about the bus from Milan to Frankfurt am Main

Compare all providers like FlixBus that travel 4 times every day by bus from Milan to Frankfurt am Main in one click! Book your bus ticket from Milan to Frankfurt am Main starting from $38!

Cheapest Bus	$38
Fastest Bus	9h 35m
Earliest Bus	1:15 AM
Latest Bus	8:25 PM
Daily Bus Routes	4 Ø
Distance	321.9 miles
Bus Companies	FlixBus

Cheapest bus connections from Milan to Frankfurt am Main

Every day, 4 buses from 1 bus companies leave Milan for Frankfurt am Main: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

$52

Saturday 02/07

$46

Sunday 02/08

$50

Monday 02/09

$41

Tuesday 02/10

$42

Wednesday 02/11

$41

Thursday 02/12

$46

Friday 02/13

$106

Saturday 02/14

$52

Sunday 02/15

$54

Monday 02/16

$45

Tuesday 02/17

$45

Wednesday 02/18

$42

Thursday 02/19

$42

Friday 02/20

$46

Saturday 02/21

$41

Sunday 02/22

$45

Monday 02/23

$41

Tuesday 02/24

$39

Wednesday 02/25

$41

Thursday 02/26

$38

Friday 02/27

$39

Saturday 02/28

The cheapest time to travel from Milan to Frankfurt am Main

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Frankfurt am Main, for the next 30 days.

With a price starting from $38, Monday is the cheapest day for a bus from Milan to Frankfurt am Main. Sunday instead is the most expensive day with prices starting from $41.

Night is the cheapest day time for bus tickets from Milan to Frankfurt am Main, with $38. Afternoon is the most expensive time of the day with prices starting from $47.

How to save money travelling from Milan to Frankfurt am Main

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Frankfurt am Main in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Frankfurt am Main, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Frankfurt am Main are also emptier.

Beloved bus companies from Milan to Frankfurt am Main

These are the most booked bus companies between Milan to Frankfurt am Main from our users.

FlixBus from Milan to Frankfurt am Main

Here you will find the key facts about the FlixBus bus route Milan to Frankfurt am Main:

Cheapest Price	$41
Fastest Bus	9h 35m
Earliest Bus	1:15 AM
Last Bus	8:25 PM
Daily Connections	4 Ø
Found on	2/5/2026

All bus stations and stops in Milan and Frankfurt am Main

In the map below, you can see where to find all bus stations in Milan and Frankfurt am Main.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Karlsruher Straße 10

Stuttgarter Strasse Bus Stop

Stuttgarter Str.

Seilerstraße Bus Stop

Baseler Platz Bus Stop

Stresemannallee/Mörfelder Landstr. Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Frankfurt am Main? Compare all modes of transports from Milan to Frankfurt am Main.

Service and Comfort on the bus from Milan to Frankfurt am Main

Want to know which seat classes are available on the buses from Milan to Frankfurt am Main? Or which bus companies serve the route Milan to Frankfurt am Main? Below you will find answers to your questions.

FAQs about the Milan to Frankfurt am Main bus

How much does a Milan Frankfurt am Main bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $38 and takes 9h 35m to reach Frankfurt am Main. Compare offers to save money!

How much could I save by comparing buses from Milan to Frankfurt am Main?

This route is offered by 1 companies with a range of ticket prices between $38 and $87. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Frankfurt am Main.

On average, how many connections are available from Milan to Frankfurt am Main each day?

Every day, the Milan to Frankfurt am Main bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Frankfurt am Main take?

The fastest bus from Milan to Frankfurt am Main is offered by FlixBus and takes 9h 35m. Bus tickets for this connection cost $52. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Frankfurt am Main?

The earliest bus arriving in Frankfurt am Main from Milan starts at 1:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Frankfurt am Main?

The latest bus trip departing from Milan for Frankfurt am Main starts at 8:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Frankfurt am Main route?

When traveling by bus from Milan to Frankfurt am Main, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Frankfurt am Main?

You can check all the direct connections between Milan and Frankfurt am Main by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Milan to Frankfurt am Main bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Frankfurt am Main bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Frankfurt am Main bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Frankfurt am Main on your planned travel date.

How does CheckMyBus find the best bus deals from Milan to Frankfurt am Main?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Milan and Frankfurt am Main. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Frankfurt am Main?

Prices and availability for 4 trips between Milan and Frankfurt am Main change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Frankfurt am Main

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Frankfurt am Main

Here’s an overview of the most popular bus routes to Milan and to Frankfurt am Main. Simply click on the connection of your choice, and you will find all the details about your bus route!