Bus from Prague to Frankfurt am Main from $35

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Compare all timetables for the bus from Prague to Frankfurt am Main

Here is a selection of the cheapest bus trips from the schedule from Prague to Frankfurt am Main from various bus operators like FlixBus for the next days.

today
from $51
tomorrow
from $58
Monday
from $43
Tuesday
from $35
Wednesday
from $38
Thursday
from $35
Friday
from $45

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    7h 35m
    0
    9:10 AM
    Prague
    Na Knížecí Station
    4:45 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $51
  • FlixBus
    7h 55m
    0
    8:50 AM
    Prague
    ÚAN Florenc
    4:45 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $51
  • FlixBus
    9h 0m
    0
    12:30 PM
    Prague
    ÚAN Florenc
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $52
  • FlixBus
    8h 40m
    0
    12:50 PM
    Prague
    Hradčanská
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $52
  • FlixBus
    7h 45m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    6:00 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $53

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    7h 30m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $58
  • FlixBus
    7h 10m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $58
  • FlixBus
    7h 35m
    0
    4:15 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    8h 10m
    0
    9:50 PM
    Prague
    Na Knížecí Station
    6:00 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $64
  • FlixBus
    10h 0m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    8:15 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $64

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    7h 30m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $43
  • FlixBus
    7h 10m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $43
  • FlixBus
    7h 35m
    0
    4:15 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $45
  • FlixBus
    6h 55m
    0
    11:05 PM
    Prague
    ÚAN Florenc
    6:00 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $48
  • FlixBus
    8h 55m
    0
    7:05 PM
    Prague
    Wilsonova Bus Station
    4:00 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $50
  • Did you know that if you travel from Prague to Frankfurt am Main via Karlovy Vary, you can save more than $8? You can find the corresponding connections below.
    • FlixBus
      9h 10m
      0
      12:20 PM
      Prague
      Hradčanská
      2:00 PM
      Karlovy Vary
      Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 0h 35m
    • FlixBus
      6h 55m
      0
      2:35 PM
      Karlovy Vary
      Bus Station
      9:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $27
    Travel time is 2h 15m longer, but you will save $8

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    9h 0m
    0
    12:30 PM
    Prague
    ÚAN Florenc
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $35
  • FlixBus
    8h 40m
    0
    12:50 PM
    Prague
    Hradčanská
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $35
  • FlixBus
    8h 0m
    0
    10:55 AM
    Prague
    Na Knížecí Station
    6:55 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    8h 25m
    0
    10:30 AM
    Prague
    ÚAN Florenc
    6:55 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    7h 35m
    0
    9:10 AM
    Prague
    Na Knížecí Station
    4:45 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $38

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    7h 30m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    7h 10m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    7h 35m
    0
    9:10 AM
    Prague
    Na Knížecí Station
    4:45 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    7h 55m
    0
    8:50 AM
    Prague
    ÚAN Florenc
    4:45 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    7h 35m
    0
    4:15 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $38

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    9h 0m
    0
    12:30 PM
    Prague
    ÚAN Florenc
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $35
  • FlixBus
    8h 40m
    0
    12:50 PM
    Prague
    Hradčanská
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $35
  • FlixBus
    7h 30m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    7h 10m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    7h 35m
    0
    4:15 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $38

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    9h 0m
    0
    12:30 PM
    Prague
    ÚAN Florenc
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $45
  • FlixBus
    8h 40m
    0
    12:50 PM
    Prague
    Hradčanská
    9:30 PM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $45
  • FlixBus
    7h 30m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $46
  • FlixBus
    8h 55m
    0
    7:05 PM
    Prague
    Wilsonova Bus Station
    4:00 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $46
  • FlixBus
    7h 10m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    11:20 AM
    Frankfurt am Main
    Central Station
    0
    FlixBus
    Economy
    $46
  • Did you know that if you travel from Prague to Frankfurt am Main via Karlovy Vary, you can save more than $10? You can find the corresponding connections below.
    • FlixBus
      9h 10m
      0
      12:20 PM
      Prague
      Hradčanská
      2:00 PM
      Karlovy Vary
      Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 0h 35m
    • FlixBus
      6h 55m
      0
      2:35 PM
      Karlovy Vary
      Bus Station
      9:30 PM
      Frankfurt am Main
      Central Station
      0
      FlixBus
      Economy
      $27
    Travel time is 2h 0m longer, but you will save $10

Frequency of bus connections between Prague and Frankfurt am Main

See here how frequent the connections between Prague and Frankfurt am Main are, during different times and days of the week.
Sunday is the busiest day, with more than 20 daily buses from Prague to Frankfurt am Main. Friday has instead the fewest connections, with only 17 daily coaches between Prague and Frankfurt am Main.
The busiest time of the day is the Evening, with 42 buses from Prague to Frankfurt am Main, while Night sees the fewest connections between Prague and Frankfurt am Main, with 14 offers.

Facts about the bus from Prague to Frankfurt am Main

Compare all providers like FlixBus that travel 18 times every day by bus from Prague to Frankfurt am Main in one click! Book your bus ticket from Prague to Frankfurt am Main starting from $35!

Cheapest Bus $35
Fastest Bus 6h 55m
Earliest Bus 3:50 AM
Latest Bus 11:05 PM
Daily Bus Routes 18 Ø
Distance 255.2 miles
Bus Companies FlixBus

Cheapest bus connections from Prague to Frankfurt am Main

Every day, 18 buses from 1 bus companies leave Prague for Frankfurt am Main: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/12/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12
$51
Sunday 07/13
$58
Monday 07/14
$34
Tuesday 07/15
$33
Wednesday 07/16
$34
Thursday 07/17
$34
Friday 07/18
$45
Saturday 07/19
$33
Sunday 07/20
$45
Monday 07/21
$33
Tuesday 07/22
$36
Wednesday 07/23
$36
Thursday 07/24
$33
Friday 07/25
$39
Saturday 07/26
$34
Sunday 07/27
$39
Monday 07/28
$33
Tuesday 07/29
$30
Wednesday 07/30
$33
Thursday 07/31
$34
Friday 08/01
$34
Saturday 08/02

The cheapest time to travel from Prague to Frankfurt am Main

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Frankfurt am Main, for the next 30 days.
With a price starting from $35, Tuesday is the cheapest day for a bus from Prague to Frankfurt am Main. Sunday instead is the most expensive day with prices starting from $58.
Afternoon is the cheapest day time for bus tickets from Prague to Frankfurt am Main, with $35. Evening is the most expensive time of the day with prices starting from $40.

How to save money travelling from Prague to Frankfurt am Main

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Frankfurt am Main in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Frankfurt am Main, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Frankfurt am Main are also emptier.

Beloved bus companies from Prague to Frankfurt am Main

These are the most booked bus companies between Prague to Frankfurt am Main from our users.

FlixBus from Prague to Frankfurt am Main

FlixBus

Here you will find the key facts about the FlixBus bus route Prague to Frankfurt am Main:

Cheapest Price $35
Fastest Bus 6h 55m
Earliest Bus 3:50 AM
Last Bus 11:05 PM
Daily Connections 18 Ø
Found on 7/11/2025

All bus stations and stops in Prague and Frankfurt am Main

In the map below, you can see where to find all bus stations in Prague and Frankfurt am Main.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Frankfurt am Main? Compare all modes of transports from Prague to Frankfurt am Main.

Service and Comfort on the bus from Prague to Frankfurt am Main

Want to know which seat classes are available on the buses from Prague to Frankfurt am Main? Or which bus companies serve the route Prague to Frankfurt am Main? Below you will find answers to your questions.

FAQs about the Prague to Frankfurt am Main bus

How much does a Prague Frankfurt am Main bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $35 and takes 9h 0m to reach Frankfurt am Main. Compare offers to save money!

How much could I save by comparing buses from Prague to Frankfurt am Main?

This route is offered by 1 companies with a range of ticket prices between $35 and $128. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Frankfurt am Main.

On average, how many connections are available from Prague to Frankfurt am Main each day?

Every day, the Prague to Frankfurt am Main bus route is served by approximately 18 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Frankfurt am Main take?

The fastest bus from Prague to Frankfurt am Main is offered by FlixBus and takes 6h 55m. Bus tickets for this connection cost $58. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Frankfurt am Main?

The earliest bus arriving in Frankfurt am Main from Prague starts at 3:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Frankfurt am Main?

The latest bus trip departing from Prague for Frankfurt am Main starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Frankfurt am Main route?

When traveling by bus from Prague to Frankfurt am Main, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Frankfurt am Main?

You can check all the direct connections between Prague and Frankfurt am Main by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Prague to Frankfurt am Main bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Frankfurt am Main bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Frankfurt am Main bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Frankfurt am Main on your planned travel date.

Available seat classes which are offered on the bus route Prague to Frankfurt am Main

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Frankfurt am Main

Here’s an overview of the most popular bus routes to Prague and to Frankfurt am Main. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Pilsen - Prague Bus Pilsen - Prague
Bus London to Prague Bus London to Prague
Buses Salzburg to Prague Buses Salzburg to Prague
From Karlovy Vary to Prague bus From Karlovy Vary to Prague bus
Buses Rome - Frankfurt am Main Buses Rome - Frankfurt am Main
Buses Birmingham to Frankfurt am Main Buses Birmingham to Frankfurt am Main
Zagreb to Frankfurt am Main bus Zagreb to Frankfurt am Main bus
Bus to Frankfurt am Main from Istanbul Bus to Frankfurt am Main from Istanbul
Popular Airport Shuttles to Prague and to Frankfurt am Main
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